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Priya Life Science Compound trial record
Compound · clinical trials

Eylea clinical trials

Source: ClinicalTrials.gov, U.S. National Library of Medicine — the 18 trials in our USA, UK, Spain, Canada, Germany, France, Italy, Switzerland, Mexico, Australia, Japan, Poland, Israel, Czechia, Portugal, Brazil, China and Sweden registers that name Eylea as an intervention. Synced 9 Nov 2026
18Current trials
9Recruiting now
14Lead sponsors
18Country registers
At a glance

Eylea is named as an intervention in 18 current clinical trials in our USA, UK, Spain, Canada, Germany, France, Italy, Switzerland, Mexico, Australia, Japan, Poland, Israel, Czechia, Portugal, Brazil, China and Sweden registers. 9 are recruiting patients now. The most common phase is Phase 3. The sponsor with the most trials is AbbVie (2). The most-studied condition is Diabetic Retinopathy.

Patient leaflets for Eylea

The package leaflet is the official guide for patients that comes with every medicine. These links go to the regulators that publish it.

  • UK
    United Kingdom: Search MHRA Products
    Patient information leaflets and SmPCs for UK-licensed products.
  • US
    United States: Search DailyMed
    FDA-approved labels, including patient and medication guides.

Leaflets differ between brands and countries; always read the one that comes with your own medicine. This is regulatory information, not medical advice.

Trials by status

  • Recruiting950%
  • Not yet open16%
  • Active, closed844%

Trials by phase

  • Phase 3633%
  • Phase 2317%
  • Phase 2/3211%
  • Observational211%
  • Phase 1211%
  • Phase 416%
  • Phase 1/216%
  • Not applicable16%
01

Clinical trials of Eylea

18 trials
StudyPhaseStatusLead sponsorRegisters
A Clinical Trial of MK-8748 Compared to Aflibercept in Participants With Diabetic Macular Edema (MK-8748-004)
NCT07705555 · Diabetic Retinopathy, Macular Edema
Phase 3 Recruiting Merck Sharp & Dohme LLC UK, USA, Australia
A Clinical Trial of MK-8748 Compared to Aflibercept in Participants With Diabetic Macular Edema (MK-8748-005)
NCT07705607 · Diabetic Retinopathy, Macular Edema
Phase 3 Recruiting Merck Sharp & Dohme LLC USA
A Study to Evaluate the Efficacy and Safety of Tabirafusp Tedromer Compared to Aflibercept in Participants With DME - ALTO
NCT07734844 · Diabetic Macular Edema (DME)
Phase 3 Recruiting Kodiak Sciences Inc USA
A Clinical Trial of EYE201/MK-8748 in People With Macular Degeneration (MK-8748-002)
NCT07440225 · Macular Degeneration, Age-Related Macular Degeneration, Choroidal Neovascularization
Phase 2/3 Recruiting EyeBiotech Ltd UK, USA, Germany, Spain, Poland, Switzerland, Mexico, Australia, Israel
A Clinical Trial of EYE201/MK-8748 in People With Macular Degeneration (MK-8748-003)
NCT07496567 · Macular Degeneration, Age-Related Macular Degeneration, Choroidal Neovascularization
Phase 2/3 Recruiting EyeBiotech Ltd USA, France, Spain, Italy, Czechia, Portugal, Brazil
Multicenter, Phase I/II Study to Evaluate the Safety, Tolerability, PK and Efficacy of SCT520FF in Patients With nAMD
NCT06672536 · ClinicalTrials.gov ↗ · nAMD
Phase 1/2 Recruiting Sinocelltech Ltd China
Study to Evaluate the Safety of CG-P5 Peptide Eye Drops in Patients Diagnosed With Age-related Wet Macular Degeneration
NCT06132035 · Age-related Wet Macular Degeneration
Phase 1 Recruiting Caregen Co. Ltd USA
An Observational Study to Collect Data on How Aflibercept (Eylea) Given Using a Paediatric Dosing Device is Used in Preterm Babies With Retinopathy of Prematurity in the United Kingdom (UK)
NCT06315556 · Retinopathy of Prematurity, Preterm Infants
Observational Recruiting Bayer UK
EarLy Treatment Response in nEoVascular Macular Degeneration With Eylea 8mg: ELEV8 A Prospective Observational Open Label Study Investigating the Fluid Dynamics During Early Response to Aflibercept 8mg in Patients With Exudative Age-related Macular Degeneration (AMD).
NCT07434713 · ClinicalTrials.gov ↗ · Age-Related Macular Degeneration (AMD)
Observational Recruiting Insel Gruppe AG, University Hospital Bern Switzerland
A Phase 3 Clinical Trial to Compare RBS-001 to Eylea® in Subjects With Neovascular Age-Related Macular Degeneration
NCT06470373 · ClinicalTrials.gov ↗ · Neovascular Age-related Macular Degeneration (nAMD)
Phase 3 Not yet open Rophibio, Inc USA
A Study of Intravitreal ILUVIEN® Implant as Baseline Therapy in Patients With Early Diabetic Macular Edema (DME)
NCT04469595 · Diabetic Macular Edema
Phase 4 Active, closed Alimera Sciences USA
Pivotal 2 Study of RGX-314 Gene Therapy in Participants With nAMD
NCT05407636 · AMD, nAMD, Wet Age-related Macular Degeneration
Phase 3 Active, closed AbbVie UK, USA, Germany, France, Spain, Italy, Canada, Japan
A Study to Evaluate the Efficacy and Safety of Tarcocimab Tedromer and Tabirafusp Tedromer Compared to Aflibercept in Participants With Neovascular (Wet) Age-related Macular Degeneration (wAMD) - DAYBREAK
NCT06556368 · Wet Age-related Macular Degeneration
Phase 3 Active, closed Kodiak Sciences Inc USA
The Sahlgrenska Anti-VEGF Study
NCT04101877 · ClinicalTrials.gov ↗ · Neovascular Age-related Macular Degeneration
Phase 2 Active, closed Vastra Gotaland Region Sweden
Long-Term Follow-Up Study of RGX-314 Administered in the Suprachoroidal Space for Participants With and Without Diabetic Retinopathy
NCT05296447 · Diabetic Retinopathy, DR
Phase 2 Active, closed AbbVie USA, Mexico
4D-150 in Patients With Diabetic Macular Edema
NCT05930561 · Diabetic Macular Edema, Diabetic Retinopathy
Phase 2 Active, closed 4D Molecular Therapeutics USA
Testing the PD-1 Antibody, MK3475, Given With Ziv-aflibercept in Patients With Advanced Cancer
NCT02298959 · ClinicalTrials.gov ↗ · Clinical Stage IV Cutaneous Melanoma AJCC v8, Metastatic Colorectal Carcinoma, Metastatic Malignant Solid Neoplasm
Phase 1 Active, closed National Cancer Institute (NCI) Canada
Mean Visual Acuity Changes Following Five Injections of Aflibercept
NCT02645266 · ClinicalTrials.gov ↗ · Diabetic Macular Edema
Not applicable Active, closed McMaster University Canada

Registers list studies that are recruiting, about to open, active but closed to enrolment, or enrolling by invitation. The UK and USA registers cover industry-sponsored studies only. Trial titles and statuses are copied from the registry as published.

02

Conditions studied with Eylea

23 conditions
Diabetic Retinopathy3Diabetic Macular Edema3nAMD2Wet Age-related Macular Degeneration2Macular Degeneration2Age-Related Macular Degeneration2Choroidal Neovascularization2Wet Macular Degeneration2Macular Edema2AMD1wAMD1Retinopathy of Prematurity1
All 23 conditions
Condition (as registered)Trials
Diabetic Retinopathy3
Diabetic Macular Edema3
nAMD2
Wet Age-related Macular Degeneration2
Macular Degeneration2
Age-Related Macular Degeneration2
Choroidal Neovascularization2
Wet Macular Degeneration2
Macular Edema2
AMD1
wAMD1
Retinopathy of Prematurity1
Preterm Infants1
Neovascular Age-related Macular Degeneration (nAMD)1
Age-related Wet Macular Degeneration1
Diabetic Retinopathy, DR1
Diabetic Macular Edema (DME)1
Neovascular Age-related Macular Degeneration1
Age-Related Macular Degeneration (AMD)1
Clinical Stage IV Cutaneous Melanoma AJCC v81
Metastatic Colorectal Carcinoma1
Metastatic Malignant Solid Neoplasm1
Metastatic Melanoma1
05

Related compounds

06

Questions about Eylea trials

How many clinical trials are testing Eylea?

18 current trials in our USA, UK, Spain, Canada, Germany, France, Italy, Switzerland, Mexico, Australia, Japan, Poland, Israel, Czechia, Portugal, Brazil, China and Sweden registers name Eylea as a drug or biological intervention, as of the registry sync on 9 November 2026. Completed and withdrawn studies are not counted.

Are Eylea trials recruiting patients?

Yes. 9 of the 18 trials are recruiting: 6 with sites in USA, 3 with sites in UK, 2 with sites in Spain, 1 with sites in Germany, 1 with sites in France, 1 with sites in Italy, 2 with sites in Switzerland, 1 with sites in Mexico, 2 with sites in Australia, 1 with sites in Poland, 1 with sites in Israel, 1 with sites in Czechia, 1 with sites in Portugal, 1 with sites in Brazil and 1 with sites in China. Eligibility and site contacts are on each trial's record. Only the study team can confirm whether a patient is eligible.

Who sponsors Eylea clinical trials?

AbbVie (2), EyeBiotech Ltd (2), Merck Sharp & Dohme LLC (2) and Kodiak Sciences Inc (2), among 14 lead sponsors in total. The number in brackets is how many trials each organisation leads.

Where does this information come from?

Every trial, status, phase and sponsor on this page is copied from public ClinicalTrials.gov records by a daily sync. Nothing here describes how Eylea works or whether it is effective, and it is not medical advice.

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How this page is built

Everything on this page is copied from public ClinicalTrials.gov registry records — it is not written from memory, and nothing here describes how Eylea works or whether it is effective. Each trial links to its own record so you can check it yourself.

This page is built automatically: a daily sync job reads the registry records behind our country trial registers, collects every trial that lists Eylea (or a registered synonym) as a drug or biological intervention, and tabulates the registry fields directly. Placebos and generic comparators are excluded. There is no AI drafting and no per-compound editorial pass, and the page has not been clinically reviewed. The “last verified” date above is the timestamp of that sync, not a review date. Our general editorial approach is described in our editorial standards and corrections policy. The ClinicalTrials.gov data on this page was last retrieved on 9 Nov 2026. How every register is built: methodology · fixes we have made: corrections log.

Please verify before you rely on this. This page is general information for life-science and pharmaceutical professionals. It is not medical advice, and it has not been reviewed by a clinician — our editorial team holds life-science qualifications, not clinical ones. It is not exhaustive and may not reflect the most recent label change. Always check the official prescribing information (US Prescribing Information or EU SmPC) and speak to your doctor or pharmacist before acting on anything here. Drugs in the same class are not automatically interchangeable, and approvals, brand names and indications differ between the US, the EU/Ireland (EMA/HPRA) and other regions. Spotted an error? Tell us — we correct promptly and log it.