Ireland
--:--IST
Latest
Astellas Expands Its 330 Million Euro Tralee Biopharma Facility with a Second Aseptic Filling Line to Double Drug-Product Capacity Xeolas Pharmaceuticals Opens 158,000 Sq Ft State-of-the-Art Baldoyle Facility to Scale Specialty Medicine Manufacturing Priya Life Science Partners with Fleming for the 9th Annual Corporate Compliance & Transparency in Life Sciences Summit in Zurich Ireland Has the Capital and the Lessons: Digital Project Management Is How They Become Delivery Dunbar Pharma Brings First Plant-Derived Dronabinol API to UK Market Through IPS Pharma Leveraging Priya Life Science as a Data Tracker: The Ultimate Use Case & Career Guide Astellas Expands Its 330 Million Euro Tralee Biopharma Facility with a Second Aseptic Filling Line to Double Drug-Product Capacity Xeolas Pharmaceuticals Opens 158,000 Sq Ft State-of-the-Art Baldoyle Facility to Scale Specialty Medicine Manufacturing Priya Life Science Partners with Fleming for the 9th Annual Corporate Compliance & Transparency in Life Sciences Summit in Zurich Ireland Has the Capital and the Lessons: Digital Project Management Is How They Become Delivery Dunbar Pharma Brings First Plant-Derived Dronabinol API to UK Market Through IPS Pharma Leveraging Priya Life Science as a Data Tracker: The Ultimate Use Case & Career Guide
Clinical Trials in Portugal / NCT07638358
Recruiting Phase EARLY_PHASE1

Assessment of the Impact of Neobone® (Biphasic Calcium Phosphate) on Bone Volume in Alveolar Ridge Preservation After Tooth Extraction

NCT07638358 · tracked via the Priya Life Science Portugal tracker
Sponsor
Egas Moniz - Cooperativa de Ensino Superior, CRL
Phase
Phase EARLY_PHASE1
Started
2025-12-01
Last updated
2026-06-11

Condition(s) studied

Tooth Extraction Site HealingAlveolar Ridge Preservation

Investigational drug(s) / intervention(s)

Neobone® (Biphasic Calcium Phosphate)

Neobone® (Biphasic Calcium Phosphate): After tooth extraction the socket will be grafted with Neobone® (Biphasic Calcium Phosphate)

Study summary

The goal of this randomized clinical trial is to assess whether BCP (Biphasic Calcium Phosphate) improves alveolar ridge preservation (ARP) in patients who need tooth extraction. The main question it aims to answer is whether using BCP for alveolar ridge preservation has a positive effect on bone volume compared with natural healing.

The main questions it aims to answer are:

Does BCP improve ridge preservation compared with natural healing?

Researchers will compare BCP grafted sockets to natural healing sockets to see if BCP better preserves ridge volume.

Participants will:

Have a tooth indicated for extraction.

Be assigned to either BCP or natural healing.

Undergo CBCT (Cone Beam Computed Tomography) and intra-oral scanning after extraction and after six months of healing to measure horizontal and vertical resorption and bone density.

Eligibility

Sex
ALL
Min age
18 Years
Max age
—
Healthy volunteers
Accepted
Inclusion Criteria: * 18 years or older * Acceptance of informed consent * Type 1 or 2 extraction sockets (Elian et al. 2007) Exclusion Criteria: * Presence of active infection or severe inflammation in the intervention zone * Relevant medical history that contraindicates implant surgery * Patients with poor oral hygiene (full-mouth plaque score and full-mouth bleeding score \>15%) and lack of motivation * Uncontrolled diabetes (reported levels of glycated haemoglobin exceeding 7%) * Uncontrolled and /or untreated periodontal disease * Heavy smokers (more than 10 cigarettes per day) * Immunosuppression

Primary outcome measure(s)

Trial sites (1)

FacilityCityRegionStatus
Clinica Dentária Egas Moniz Caparica Monte Da Caparica Recruiting

More Egas Moniz - Cooperativa de Ensino Superior, CRL trials in Portugal

Comparing Vascular Responses to Resistance Exercise with and Without Blood Flow Restriction in Young and Older Adults Recruiting
Effects of Transcranial Electrical Stimulation in Chronic Stress Starting soon
tDCS for Social Media Addiction Recruiting
Assessment of the Impact of Neocement Inject P® (Beta-Tricalcium Phosphate) on Bone Volume in Alveolar Ridge Preservation After Tooth Extraction Recruiting
The Effect of Different Focus of Attention Instructions on Resistance Training and Its Transfer to Gait Parameters in Older Adults Recruiting

Other trials for the same condition

Assessment of the Impact of Neocement Inject P® (Beta-Tricalcium Phosphate) on Bone Volume in Alveolar Ridge Preservation After Tooth Extraction Recruiting
Official registry record

This page summarises publicly available registry data for informational purposes — not medical advice. Eligibility is determined by each study team; patients should discuss participation with their clinician.

View NCT07638358 on ClinicalTrials.gov ↗ ← All trials in Portugal