EYLEA (aflibercept) clinical trials
EYLEA (aflibercept) is named as an intervention in 3 current clinical trials in our USA, UK, Germany, France, Spain, Italy, Portugal, Japan, South Korea, Singapore, Australia, Israel, Canada and Mexico registers. 2 are recruiting patients now. The most common phase is Phase 3. The sponsor with the most trials is 4D Molecular Therapeutics (2). The most-studied condition is Neovascular Age-Related Macular Degeneration (nAMD).
Patient leaflets for EYLEA (aflibercept)
The package leaflet is the official guide for patients that comes with every medicine. These links go to the regulators that publish it.
- UKUnited Kingdom: Search MHRA ProductsPatient information leaflets and SmPCs for UK-licensed products.
- USUnited States: Search DailyMedFDA-approved labels, including patient and medication guides.
Leaflets differ between brands and countries; always read the one that comes with your own medicine. This is regulatory information, not medical advice.
Trials by status
Trials by phase
Clinical trials of EYLEA (aflibercept)
3 trials| Study | Phase | Status | Lead sponsor | Registers |
|---|---|---|---|---|
|
Single Intravitreal (IVT) Injection of 4D-150 in Patients With Macular Neovascularization Secondary to Age-Related Macular Degeneration
NCT07064759 · Neovascular Age-Related Macular Degeneration (nAMD)
|
Phase 3 | Recruiting | 4D Molecular Therapeutics | UK, USA, Germany, France, Spain, Italy, Portugal, Japan, South Korea, Singapore, Australia, Israel |
|
Safety and Efficacy of AIV007 Periocular Injection in Patients With Neovascular Age-Related Macular Degeneration
NCT07557121 · ClinicalTrials.gov ↗ · Neovascular (Wet) Age-Related Macular Degeneration
|
Phase 2 | Recruiting | AiViva BioPharma, Inc | USA |
|
4D-150 in Patients With Macular Neovascularization Secondary to Age-Related Macular Degeneration
NCT06864988 · Macular Neovascularization Secondary to Age-Related Macular Degeneration
|
Phase 3 | Active, closed | 4D Molecular Therapeutics | USA, Canada, Mexico |
Registers list studies that are recruiting, about to open, active but closed to enrolment, or enrolling by invitation. The UK and USA registers cover industry-sponsored studies only. Trial titles and statuses are copied from the registry as published.
Conditions studied with EYLEA (aflibercept)
3 conditionsSponsors
lead sponsor per trial| Lead sponsor | Trials |
|---|---|
| 4D Molecular Therapeutics | 2 |
| AiViva BioPharma, Inc | 1 |
By country register
A trial with sites in more than one country appears in each of those registers.
Related compounds
Questions about EYLEA (aflibercept) trials
How many clinical trials are testing EYLEA (aflibercept)?
3 current trials in our USA, UK, Germany, France, Spain, Italy, Portugal, Japan, South Korea, Singapore, Australia, Israel, Canada and Mexico registers name EYLEA (aflibercept) as a drug or biological intervention, as of the registry sync on 10 November 2026. Completed and withdrawn studies are not counted.
Are EYLEA (aflibercept) trials recruiting patients?
Yes. 2 of the 3 trials are recruiting: 2 with sites in USA, 1 with sites in UK, 1 with sites in Germany, 1 with sites in France, 1 with sites in Spain, 1 with sites in Italy, 1 with sites in Portugal, 1 with sites in Japan, 1 with sites in South Korea, 1 with sites in Singapore, 1 with sites in Australia and 1 with sites in Israel. Eligibility and site contacts are on each trial's record. Only the study team can confirm whether a patient is eligible.
Who sponsors EYLEA (aflibercept) clinical trials?
4D Molecular Therapeutics (2) and AiViva BioPharma, Inc (1). The number in brackets is how many trials each organisation leads.
Where does this information come from?
Every trial, status, phase and sponsor on this page is copied from public ClinicalTrials.gov records by a daily sync. Nothing here describes how EYLEA (aflibercept) works or whether it is effective, and it is not medical advice.
How this page is built
Everything on this page is copied from public ClinicalTrials.gov registry records — it is not written from memory, and nothing here describes how EYLEA (aflibercept) works or whether it is effective. Each trial links to its own record so you can check it yourself.
- ClinicalTrials.gov (U.S. National Library of Medicine) ↗ Trial IDs, titles, intervention names and synonyms, phase, overall status, lead sponsor and conditions for every trial on this page
This page is built automatically: a daily sync job reads the registry records behind our country trial registers, collects every trial that lists EYLEA (aflibercept) (or a registered synonym) as a drug or biological intervention, and tabulates the registry fields directly. Placebos and generic comparators are excluded. There is no AI drafting and no per-compound editorial pass, and the page has not been clinically reviewed. The “last verified” date above is the timestamp of that sync, not a review date. Our general editorial approach is described in our editorial standards and corrections policy. The ClinicalTrials.gov data on this page was last retrieved on 10 Nov 2026. How every register is built: methodology · fixes we have made: corrections log.