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Compound · clinical trials

Efgartigimod

Source: ClinicalTrials.gov, U.S. National Library of Medicine — the 10 trials in our USA, UK, China and Ireland registers that name Efgartigimod as an intervention. Synced 24 Sep 2026
10Trials tracked
8Recruiting now
2Lead sponsors
4Country registers
Maintained by Sreepriya Prasannan
MSc Digital Transformation of Life Sciences (Innopharma Education / Griffith College); MSc & BSc Botany HSE Spark Ignite 2026 โ€” Top 14 finalist
Compiled from ClinicalTrials.gov registry records ยท Last verified ยท Editorial standards

Efgartigimod is named as a drug or biological intervention in 10 clinical trials in our USA, UK, China and Ireland trial registers, 8 of which are recruiting. Lead sponsors include argenx (9) and Janssen Research & Development, LLC (1). Registered phases: Phase 3, Phase 2/3, Observational and Phase 2. Conditions studied include Myasthenia Gravis; Generalized Myasthenia Gravis; gMG.

01

Clinical trials of Efgartigimod

10 trials
NCT IDStudyPhaseStatusLead sponsorRegister
NCT06544499 A Study to Assess the Efficacy and Safety of Efgartigimod IV in Adult Participants With Primary Immune Thrombocytopenia (ClinicalTrials.gov ↗)
Primary Immune Thrombocytopenia (ITP)
Phase 3 Recruiting argenx Ireland, UK, USA, China
NCT07217587 Comparative Efficacy of Nipocalimab and Efgartigimod in Participants With Generalized Myasthenia Gravis
Myasthenia Gravis
Phase 3 Recruiting Janssen Research & Development, LLC USA
NCT04833894 Evaluating the Pharmacokinetics, Pharmacodynamics, and Safety of Efgartigimod Administered Intravenously in Children With Generalized Myasthenia Gravis
Generalized Myasthenia Gravis
Phase 2/3 Recruiting argenx UK, USA
NCT07194850 A Study of Efgartigimod IV in Participants From 12 Years to Less Than 18 Years of Age With Chronic Immune Thrombocytopenia (ITP) (ClinicalTrials.gov ↗)
Immune Thrombocytopenia (ITP), ITP - Immune Thrombocytopenia, ITP
Phase 2/3 Recruiting argenx UK
NCT07284420 ADAPT Forward 1 - ISA1 - a Study to Evaluate Empasiprubart IV as add-on Therapy to Efgartigimod IV in Participants With AChR-Ab Seropositive Generalized Myasthenia Gravis With a Partial Clinical Response to Efgartigimod (ClinicalTrials.gov ↗)
AChR-Ab Seropositive Generalized Myasthenia Gravis, Myasthenia Gravis, MG
Phase 2 Recruiting argenx USA
NCT06298565 A Non-interventional, Post-authorisation Safety Study of Patients Treated With Efgartigimod Alfa
Myasthenia Gravis
Observational Recruiting argenx USA
NCT06299748 A Worldwide Pregnancy Safety Study to Assess Maternal, Fetal, and Infant Outcomes Following Exposure to Efgartigimod During Pregnancy and/or Breastfeeding. (ClinicalTrials.gov ↗)
Myasthenia Gravis, CIDP - Chronic Inflammatory Demyelinating Polyneuropathy
Observational Recruiting argenx USA
NCT07294170 ADAPT Forward - Master Protocol of a Platform Study to Evaluate the Safety and Efficacy of Multiple Regimens in Participants With Myasthenia Gravis (ClinicalTrials.gov ↗)
Myasthenia Gravis, MG, gMG
Observational Recruiting argenx USA
NCT05374590 Evaluating Long-term Safety of Efgartigimod Administered Intravenously and Efgartigimod PH20 Administered Subcutaneously in Children With Generalized Myasthenia Gravis (ClinicalTrials.gov ↗)
Generalized Myasthenia Gravis, gMG
Phase 2/3 By invitation argenx UK, USA
NCT06298552 A Phase 3 Study to Evaluate the Efficacy and Safety of Efgartigimod IV in Patients With Acetylcholine Receptor Binding Antibody Seronegative Generalized Myasthenia Gravis (ClinicalTrials.gov ↗)
Generalized Myasthenia Gravis, gMG, Myasthenia Gravis, Generalized
Phase 3 Active, closed argenx UK, USA, China

Registers list studies that are recruiting, about to open, active but closed to enrolment, or enrolling by invitation. The UK and USA registers cover industry-sponsored studies only. Trial titles and statuses are copied from the registry as published.

02

Conditions studied

12 conditions
Condition (as registered)Trials
Myasthenia Gravis6
Generalized Myasthenia Gravis4
gMG4
MG2
Primary Immune Thrombocytopenia (ITP)1
Immune Thrombocytopenia (ITP)1
ITP - Immune Thrombocytopenia1
ITP1
Immune Thrombocytopenic Purpura1
Myasthenia Gravis, Generalized1
CIDP - Chronic Inflammatory Demyelinating Polyneuropathy1
AChR-Ab Seropositive Generalized Myasthenia Gravis1
03

Sponsors

lead sponsor per trial
Lead sponsorTrials
argenx9
Janssen Research & Development, LLC1
04

Trials by country register

A trial with sites in more than one country appears in each of those registers.

How this page is built

Everything on this page is copied from public ClinicalTrials.gov registry records โ€” it is not written from memory, and nothing here describes how Efgartigimod works or whether it is effective. Each trial links to its own record so you can check it yourself.

This page is built automatically: a daily sync job reads the registry records behind our country trial registers, collects every trial that lists Efgartigimod (or a registered synonym) as a drug or biological intervention, and tabulates the registry fields directly. Placebos and generic comparators are excluded. There is no AI drafting and no per-compound editorial pass, and the page has not been clinically reviewed. The “last verified” date above is the timestamp of that sync, not a review date. Our general editorial approach is described in our editorial standards and corrections policy. The ClinicalTrials.gov data on this page was last retrieved on 24 Sep 2026.

Please verify before you rely on this. This page is general information for life-science and pharmaceutical professionals. It is not medical advice, and it has not been reviewed by a clinician โ€” our editorial team holds life-science qualifications, not clinical ones. It is not exhaustive and may not reflect the most recent label change. Always check the official prescribing information (US Prescribing Information or EU SmPC) and speak to your doctor or pharmacist before acting on anything here. Drugs in the same class are not automatically interchangeable, and approvals, brand names and indications differ between the US, the EU/Ireland (EMA/HPRA) and other regions. Spotted an error? Tell us โ€” we correct promptly and log it.