Efgartigimod IV or Efgartigimod PH20 SC: Intravenous infusion of Efgartigimod or Subcutaneous injection of Efgartigimod PH20 SC
The purpose of this trial is to evaluate the long-term safety of efgartigimod IV and efgartigimod PH20 SC administered to participants with gMG in the antecedent studies, ARGX-113-2006 and ARGX-113-2207, respectively.
Participants will receive efgartigimod IV or efgartigimod PH20 SC, using the dose administered in the antecedent studies. Participants who have not reached the age of 18 can remain in the study until efgartigimod becomes commercially available in the respective country or available through another continued access program for gMG. Participants who have reached the age of 18 can remain in the study for a maximum of 2 years, until efgartigimod becomes commercially available in the respective country or available through another continued access program for gMG, whichever comes first.
| Facility | City | Region | Status |
|---|---|---|---|
| Ann and Robert H Lurie Children's Hospital of Chicago - Main Hospital | Chicago | Illinois | |
| Atrium Health Neurology Specialty Care | Charlotte | North Carolina | |
| University of Virginia (UVA) Health - Developmental Pediatrics Clinic | Charlottesville | Virginia | |
| Universitair Ziekenhuis Antwerpen | Edegem | Belgium | |
| UZ Gent | Ghent | Belgium | |
| Childrens Hospital of Eastern Ontario | Ottawa | Canada | |
| AP-HM- Hôpital de La Timone | Marseille | France | |
| Universitätsklinikum Essen | Essen | Germany | |
| Hadassah Medical Center- Ein Kerem | Jerusalem | Israel | |
| Leids Universitair Medisch Centrum | Leiden | Netherlands | |
| Uniwersyteckie Centrum Kliniczne w Gdansku | Gdansk | Poland | |
| Wielospecjalistyczna Poradnia Lekarska Synapsis | Katowice | Poland | |
| Centralny Szpital Kliniczny - Uniwersyteckie Centrum Kliniczne WUM | Warsaw | Poland | |
| Hospital Universitari i Politecnic La Fe de Valencia | Valencia | Spain | |
| Great Ormand Street Hospital for Children NHS Foundation Trust - Great Ormond Street Hospital - Pediatric Neurology | London | United Kingdom | |
| Oxford University Hospitals NHS Foundation Trust - John Radcliffe Hospital Children's Hospital | Oxford | United Kingdom |
This page summarises publicly available registry data for informational purposes — not medical advice. Eligibility is determined by each study team; patients should discuss participation with their clinician.
View NCT05374590 on ClinicalTrials.gov ↗ ← All trials in the UK