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Compound · clinical trials

Ravulizumab clinical trials

Source: ClinicalTrials.gov, U.S. National Library of Medicine — the 9 trials in our USA, China, UK and India registers that name Ravulizumab as an intervention. Synced 25 Sep 2026
9Current trials
5Recruiting now
2Lead sponsors
4Country registers
Maintained by Sreepriya Prasannan
MSc Digital Transformation of Life Sciences (Innopharma Education / Griffith College); MSc & BSc Botany HSE Spark Ignite 2026 โ€” Top 14 finalist
Compiled from ClinicalTrials.gov registry records ยท Last verified ยท Editorial standards
At a glance

Ravulizumab is named as an intervention in 9 current clinical trials in our USA, China, UK and India registers. 5 are recruiting patients now. The most common phase is Phase 3. The sponsor with the most trials is Alexion Pharmaceuticals, Inc (8). The most-studied condition is Generalized Myasthenia Gravis.

Ravulizumab also has an approved-drug profile on this site (FDA label data): Ultomiris (Ravulizumab) →

Trials by status

  • Recruiting556%
  • Active, closed444%

Trials by phase

  • Phase 3778%
  • Phase 2/3111%
  • Phase 4111%
01

Clinical trials of Ravulizumab

9 trials
StudyPhaseStatusLead sponsorRegisters
A Study to Investigate OCS Tapering in Adult Participants With Generalized Myasthenia Gravis Treated With Ravulizumab
NCT07221838 · ClinicalTrials.gov ↗ · Generalized Myasthenia Gravis, gMG
Phase 4 Recruiting Alexion Pharmaceuticals, Inc. USA
Double-blind, Randomized, Placebo-controlled, Multicenter Study to Evaluate the Efficacy and Safety of Ravulizumab Administered Intravenously in Adult Participants at High Risk of Delayed Graft Function After Kidney Transplantation
NCT06830798 · ClinicalTrials.gov ↗ · Delayed Graft Function, DGF, Kidney Transplant
Phase 3 Recruiting Alexion Pharmaceuticals, Inc. UK, USA, China
Study of Ravulizumab in Pediatric Participants With Primary IgAN
NCT07024563 · ClinicalTrials.gov ↗ · IgAN, IgAVN, Immunoglobulin A Nephropathy
Phase 3 Recruiting Alexion Pharmaceuticals, Inc. USA, China
Efficacy, Safety, Pharmacokinetics, Pharmacodynamics, and Immunogenicity Study of Ravulizumab in Chinese Adults With Neuromyelitis Optica Spectrum Disorder (NMOSD)
NCT07557420 · ClinicalTrials.gov ↗ · NMOSD, Neuromyelitis Optica Spectrum Disorder
Phase 3 Recruiting Alexion Pharmaceuticals, Inc. China
Efficacy and Safety of Ravulizumab in Chinese Adults Participants With Generalized Myasthenia Gravis (gMG)
NCT07596784 · ClinicalTrials.gov ↗ · Generalized Myasthenia Gravis, gMG
Phase 3 Recruiting Alexion Pharmaceuticals, Inc. China
A Study to Evaluate How Safe Pozelimab + Cemdisiran Combination Therapy is and How Well it Works in Adult Patients With Paroxysmal Nocturnal Hemoglobinuria (PNH) Who Have Not Recently Received or Have Not Received Complement Inhibitor Treatment
NCT05133531 · ClinicalTrials.gov ↗ · Paroxysmal Nocturnal Hemoglobinuria
Phase 3 Active, closed Regeneron Pharmaceuticals UK, USA, India, China
Evaluation of PK, PD, Efficacy, Safety, and Immunogenicity of IV Ravulizumab in Pediatric Participants With Generalized Myasthenia Gravis
NCT05644561 · ClinicalTrials.gov ↗ · Generalized Myasthenia Gravis, gMG
Phase 3 Active, closed Alexion Pharmaceuticals, Inc. USA
Study of Ravulizumab in Immunoglobulin A Nephropathy (IgAN)
NCT06291376 · ClinicalTrials.gov ↗ · Immunoglobulin A Nephropathy, IgAN
Phase 3 Active, closed Alexion Pharmaceuticals, Inc. UK, USA, China
Efficacy and Safety Study of Ravulizumab IV in Pediatric Participants With NMOSD
NCT05346354 · ClinicalTrials.gov ↗ · Neuromyelitis Optica Spectrum Disorder
Phase 2/3 Active, closed Alexion Pharmaceuticals, Inc. USA

Registers list studies that are recruiting, about to open, active but closed to enrolment, or enrolling by invitation. The UK and USA registers cover industry-sponsored studies only. Trial titles and statuses are copied from the registry as published.

02

Conditions studied with Ravulizumab

12 conditions
Generalized Myasthenia Gravis3gMG3Immunoglobulin A Nephropathy2IgAN2Neuromyelitis Optica Spectrum Disorder2Paroxysmal Nocturnal Hemoglobinuria1Delayed Graft Function1DGF1Kidney Transplant1IgAVN1Immunoglobulin A Vasculitis Associated Nephritis1NMOSD1
03

Sponsors

lead sponsor per trial
Lead sponsorTrials
Alexion Pharmaceuticals, Inc.8
Regeneron Pharmaceuticals1
04

By country register

RegisterTrialsRecruiting
Clinical trials in USA73
Clinical trials in China64
Clinical trials in UK31
Clinical trials in India10

A trial with sites in more than one country appears in each of those registers.

05

Related compounds

06

Questions about Ravulizumab trials

How many clinical trials are testing Ravulizumab?

9 current trials in our USA, China, UK and India registers name Ravulizumab as a drug or biological intervention, as of the registry sync on 25 September 2026. Completed and withdrawn studies are not counted.

Are Ravulizumab trials recruiting patients?

Yes. 5 of the 9 trials are recruiting: 3 with sites in USA, 4 with sites in China and 1 with sites in UK. Eligibility and site contacts are on each trial's record. Only the study team can confirm whether a patient is eligible.

Who sponsors Ravulizumab clinical trials?

Alexion Pharmaceuticals, Inc (8) and Regeneron Pharmaceuticals (1). The number in brackets is how many trials each organisation leads.

Where does this information come from?

Every trial, status, phase and sponsor on this page is copied from public ClinicalTrials.gov records by a daily sync. Nothing here describes how Ravulizumab works or whether it is effective, and it is not medical advice.

How this page is built

Everything on this page is copied from public ClinicalTrials.gov registry records โ€” it is not written from memory, and nothing here describes how Ravulizumab works or whether it is effective. Each trial links to its own record so you can check it yourself.

This page is built automatically: a daily sync job reads the registry records behind our country trial registers, collects every trial that lists Ravulizumab (or a registered synonym) as a drug or biological intervention, and tabulates the registry fields directly. Placebos and generic comparators are excluded. There is no AI drafting and no per-compound editorial pass, and the page has not been clinically reviewed. The “last verified” date above is the timestamp of that sync, not a review date. Our general editorial approach is described in our editorial standards and corrections policy. The ClinicalTrials.gov data on this page was last retrieved on 25 Sep 2026.

Please verify before you rely on this. This page is general information for life-science and pharmaceutical professionals. It is not medical advice, and it has not been reviewed by a clinician โ€” our editorial team holds life-science qualifications, not clinical ones. It is not exhaustive and may not reflect the most recent label change. Always check the official prescribing information (US Prescribing Information or EU SmPC) and speak to your doctor or pharmacist before acting on anything here. Drugs in the same class are not automatically interchangeable, and approvals, brand names and indications differ between the US, the EU/Ireland (EMA/HPRA) and other regions. Spotted an error? Tell us โ€” we correct promptly and log it.