SHR2554 Clinical Study of Chidamide in the Treatment of T-cell Lymphoma
NCT06122389 · ClinicalTrials.gov ↗ · Relapsed/Refractory PTCLT With at Least One Line of Prior Systemic Therapy
|
Phase 3 |
Recruiting |
Jiangsu HengRui Medicine Co., Ltd |
China |
|
A Study of Tucidinostat in Combination With Sintilimab and Bevacizumab in MSS/pMMR Colorectal Cancer Patients
|
Phase 3 |
Recruiting |
Chipscreen Biosciences, Ltd |
China |
A Phase 3 Multinational Study of Golidocitinib Versus Investigator's Choice in r/r PTCL (JACKPOT19)
NCT07234162 · ClinicalTrials.gov ↗ · Peripheral T-cell Lymphoma
|
Phase 3 |
Recruiting |
Dizal Pharmaceuticals |
China, Taiwan |
Chidamide for Maintenance Treatment of HBV-infected Diffuse DLBCL in Patients Initially Treated With R-CHOP
NCT07493109 · ClinicalTrials.gov ↗ · Diffuse Large B-Cell Lymphoma (DLBCL)
|
Phase 3 |
Recruiting |
Ou Bai, MD/PHD |
China |
Venetoclax-Azacitidine in Combination With Chidamide and CAG in Fit Older Patients With Acute Myeloid Leukaemia
NCT07514936 · ClinicalTrials.gov ↗ · Newly Diagnosed Acute Myeloid Leukemia (AML), Elderly Patients
|
Phase 3 |
Recruiting |
Chinese PLA General Hospital |
China |
Ruxolitinib and Chidamide Intensified Bu/CY Conditioning Regimen
NCT05088226 · ClinicalTrials.gov ↗ · Peripheral Blood Stem Cell Transplantation
|
Phase 2 |
Recruiting |
Chinese PLA General Hospital |
China |
Venetoclax and Azacitidine Combined With Chidamide (VAC) for the Treatment of Newly Diagnosed Acute Monocytic Leukemia
NCT05566054 · ClinicalTrials.gov ↗ · Acute Monocytic Leukemia, Newly Diagnosed
|
Phase 2 |
Recruiting |
The First Affiliated Hospital of Soochow University |
China |
Chidamide in Patients With Relapsed or Refractory Peripheral T-cell Lymphoma (R/R PTCL)
NCT05833724 · ClinicalTrials.gov ↗ · Relapsed or Refractory Peripheral T-cell Lymphoma
|
Phase 2 |
Recruiting |
Great Novel Therapeutics Biotech & Medicals Corporation |
Taiwan |
|
Treatment of Chidamide and Venetoclax for Retinoic Acid and Arsenic Resistant Acute Promyelocytic Leukemia
|
Phase 2 |
Recruiting |
Shanghai Jiao Tong University School of Medicine |
China |
Chidamide in Combination With Azacitidine, Liposomal Mitoxantrone, and Prednisone (CAMP Regimen) for the Treatment of Previously Untreated Nodal TFH Cell Lymphoma
NCT05958719 · Peripheral T Cell Lymphoma, Epigenetic Repression
|
Phase 2 |
Recruiting |
Institute of Hematology & Blood Diseases Hospital, China |
China |
Chidamide/Everolimus for PIK3CA Wild-type/Mutant HR+/HER2- Advanced Breast Cancer
NCT05983107 · ClinicalTrials.gov ↗ · HR+/HER2- Advanced Breast Cancer, Targeted Therapy
|
Phase 2 |
Recruiting |
Cancer Institute and Hospital, Chinese Academy of Medical Sciences |
China |
Clinical Study of Venetoclax Combined With CACAG Regimen in the Treatment of Relapsed/Refractory Acute Myeloid Leukemia
NCT06084819 · ClinicalTrials.gov ↗ · Relapsed/Refractory Acute Myeloid Leukemia
|
Phase 2 |
Recruiting |
Chinese PLA General Hospital |
China |
Chidamide and Duvalisibon for the Treatment of Refractory/Relapsed Peripheral T-cell Lymphoma
NCT06151106 · ClinicalTrials.gov ↗ · Peripheral T Cell Lymphoma, Relapsed Peripheral T-Cell Lymphoma, Refractory T-Cell Lymphoma
|
Phase 2 |
Recruiting |
The First Affiliated Hospital of Xiamen University |
China |
Chidamide Combined With Linperlisibon for the Treatment of Refractory/Relapsed Follicular Lymphoma
NCT06158386 · ClinicalTrials.gov ↗ · Follicular Lymphoma, Refractory B-Cell Lymphoma, Relapsed Non-Hodgkin Lymphoma
|
Phase 2 |
Recruiting |
The First Affiliated Hospital of Xiamen University |
China |
VAC Regimen for AML Patients Who Failed to Response to VA Regimen
NCT06220162 · ClinicalTrials.gov ↗ · Acute Myeloid Leukemia
|
Phase 2 |
Recruiting |
The First Affiliated Hospital of Soochow University |
China |
Chidamide Decitabine Plus Anti-PD-1 Antibody for Patients With R/R cHL Who Are Transplant-ineligible or Refused Transplant.
NCT06393361 · Ineligible Or Refused Transplant Patients With Classical Hodgkin Lymphoma
|
Phase 2 |
Recruiting |
Chinese PLA General Hospital |
China |
Randomized Study of ABC-14 Regimen Compared With "3+7" Standard Induction Therapy or AB-14 for ND AML
NCT06451861 · ClinicalTrials.gov ↗ · Acute Myeloid Leukemia
|
Phase 2 |
Recruiting |
Guangdong Provincial People's Hospital |
China |
Glofitamab Combination With Chidamide in Patients With Recurrent/Refractory DLBCL
NCT06570447 · ClinicalTrials.gov ↗ · Diffuse Large B-Cell Lymphoma-Recurrent, Diffuse Large B-Cell Lymphoma-Refractory
|
Phase 2 |
Recruiting |
Tianjin Medical University Cancer Institute and Hospital |
China |
Safety and Efficacy of Fruquintinib Plus Chidamide and Sintilimab in the Third and Later Line Treatment of MSS/pMMR Metastatic Colorectal Cancer
NCT06685276 · ClinicalTrials.gov ↗ · Colorectal Cancer Metastatic
|
Phase 2 |
Recruiting |
Dai, Guanghai |
China |
HDAC Inhibitor Combination With Chemoimmunotherapy in the Neoadjuvant Treatment of pMMR Locally Advanced Colon Cancer
NCT06709885 · ClinicalTrials.gov ↗ · Colon Adenocarcinoma
|
Phase 2 |
Recruiting |
Daping Hospital and the Research Institute of Surgery of the Third Military Medical University |
China |
Precision Medicine Trial Based on Molecular Matching Therapy for Patients With Standard Treatment Exhaustion
NCT06739395 · ClinicalTrials.gov ↗ · Solid Tumor, Precision Medicine
|
Phase 2 |
Recruiting |
Tianjin Medical University Second Hospital |
China |
Clinical Study of HiR+X Therapy for Newly Diagnosed Elderly Patients With DLBCL Intolerant to Chemotherapy
NCT06758037 · ClinicalTrials.gov ↗ · DLBCL, Diffuse Large B-Cell Lymphoma
|
Phase 2 |
Recruiting |
First Affiliated Hospital of Ningbo University |
China |
Chidamide Plus R-CHOP in Newly Diagnosed Double-Expressor Diffuse Large B-Cell Lymphoma With Other Molecular Subtypes
NCT06891157 · ClinicalTrials.gov ↗ · Chidamide, R-CHOP Chemotherapy, DLBCL - Diffuse Large B Cell Lymphoma
|
Phase 2 |
Recruiting |
The First Affiliated Hospital with Nanjing Medical University |
China |
A Multicenter RCT of "3+7" vs Venetoclax + CACAG in Newly Diagnosed Mid/High-Risk AML Patients
NCT06928376 · ClinicalTrials.gov ↗ · Acute Myeloid Leukemia, First Line Therapy
|
Phase 2 |
Recruiting |
Chinese PLA General Hospital |
China |
QL1706 Plus Chidamide, AG as First-line Treatment for Metastatic Pancreatic Cancer
NCT06951997 · ClinicalTrials.gov ↗ · Metastatic Pancreatic Cancer
|
Phase 2 |
Recruiting |
Tianjin Medical University Cancer Institute and Hospital |
China |
A Clinical Study on the Efficacy and Safety of Fruquintinib in Combination With PD-1 Monoclonal Antibody and Chidamide in Refractory MSS Metastatic Colorectal Cancer
NCT06979908 · ClinicalTrials.gov ↗ · Metastatic Colorectal Cancer
|
Phase 2 |
Recruiting |
The First Hospital of Jilin University |
China |
Venetoclax Combined With Azacitidine, Chidamide, Vindesine, and Dexamethasone in Newly Diagnosed ETP-ALL Like Patients
NCT07159620 · ClinicalTrials.gov ↗ · Adult T-cell Leukemia/Lymphoma
|
Phase 2 |
Recruiting |
The First Affiliated Hospital of Soochow University |
China |
Post-transplantation Maintenance Therapy With Cidabenamide in Patients With Intermediate/High-risk AML
NCT07304232 · ClinicalTrials.gov ↗ · Allogeneic Hematopoietic Cell Transplantation (HCT), AML (Acute Myeloid Leukemia)
|
Phase 2 |
Recruiting |
Institute of Hematology & Blood Diseases Hospital, China |
China |
Phase II Study of Chidamide-Dinutuximab Beta-Irinotecan-Temozolomide for Refractory/Relapsed Neuroblastoma in Children
NCT07318831 · ClinicalTrials.gov ↗ · Neuroblastoma (NB), Neuroblastoma in Children
|
Phase 2 |
Recruiting |
Tianjin Medical University Cancer Institute and Hospital |
China |
PD-1 Antibody-based Therapy With Concurrent RT for Early-stage NKTCL
NCT07380984 · ClinicalTrials.gov ↗ · Natural Killer/T-cell Lymphoma
|
Phase 2 |
Recruiting |
Ruijin Hospital |
China |
CRP Regimen in Treating Elderly Patients With Previously Untreated Double-Positive DLBCL
NCT07397832 · ClinicalTrials.gov ↗ · Diffuse Large B-Cell Lymphoma (DLBCL)
|
Phase 2 |
Recruiting |
Tianjin Medical University Cancer Institute and Hospital |
China |
A Study of Chidamide Combined With Ivonescimab in the Treatment of Advanced Non-Small Cell Lung Cancer (NSCLC) With Acquired Resistance to Immunotherapy and High Yes-associated Protein (YAP) Expression
NCT07412262 · ClinicalTrials.gov ↗ · Non-Small Cell Lung Cancer
|
Phase 2 |
Recruiting |
Guangdong Association of Clinical Trials |
China |
Chidamide Combination With R-mini CHOP Followed by Chidamide+CD20 Maintenance in Elderly Newly Diagnosed MYC/BCL2+ DLBCL
NCT07493148 · ClinicalTrials.gov ↗ · Diffuse Large B-Cell Lymphoma (DLBCL)
|
Phase 2 |
Recruiting |
Ou Bai, MD/PHD |
China |
Chidamide Maintenance for MRD-Positive Double-Expressor DLBCL in First Complete Remission
NCT07507318 · ClinicalTrials.gov ↗ · Diffuse Large B-Cell Lymphoma
|
Phase 2 |
Recruiting |
Rong Tao |
China |
Efficacy and Safety of Chidamide+Sintilimab+Bev as Second-Line Therapy in Advanced Extrapulmonary Neuroendocrine Carcinoma
NCT07518602 · ClinicalTrials.gov ↗ · Extrapulmonary Neuroendocrine Carcinoma (EP-NEC)
|
Phase 2 |
Recruiting |
Sun Yat-sen University |
China |
Chidamide, Lenalidomide, and Rituximab in Newly Diagnosed Elderly/unFit DE-DLBCL
NCT07884708 · ClinicalTrials.gov ↗ · Double Expressor DLBCL, ELDERLY PEOPLE, Unfit, New-diagnosis DLBCL
|
Phase 2 |
Recruiting |
The First Affiliated Hospital with Nanjing Medical University |
China |
|
Comparation of Chidamide Plus VRD (Bortezomib, Lenalidomide, Dexamethasone) With VRD Regimen for Primary High-Risk Multiple Myeloma Patients
|
Phase 1/2 |
Recruiting |
The First Affiliated Hospital of Soochow University |
China |
Single Arm Study of Post-transplant Azacitidine and Chidamide for Prevention of Acute Myelogenous Leukemia Relapse
NCT05270200 · ClinicalTrials.gov ↗ · Leukemia, Myeloid, Acute
|
Phase 1/2 |
Recruiting |
Zhujiang Hospital |
China |
Genotype-guided Treatment in Newly Diagnosed PTCL
NCT05675813 · ClinicalTrials.gov ↗ · Peripheral T Cell Lymphoma
|
Phase 1/2 |
Recruiting |
Ruijin Hospital |
China |
Chidamide Prevents Recurrence of High-risk AML After Allo-HSCT
NCT05682755 · ClinicalTrials.gov ↗ · Leukemia, Myeloid, Acute
|
Phase 1/2 |
Recruiting |
Sichuan University |
China |
Golidocitinib Combined With Mitoxantrone Hydrochloride Liposome or Chidamide in the Treatment of Relapsed or Refractory Peripheral T-cell Lymphoma
NCT07093710 · ClinicalTrials.gov ↗ · Peripheral T Cell Lymphoma
|
Phase 1/2 |
Recruiting |
Sun Yat-sen University |
China |
Golidocitinib and Chidamide for Cutaneous T-Cell Lymphoma
NCT07754890 · ClinicalTrials.gov ↗ · Cutaneous T-cell Lymphoma (CTCL)
|
Phase 1/2 |
Recruiting |
Peking Union Medical College Hospital |
China |
Re-radiotherapy Combined With Chidamide for the Treatment of Recurrent Head and Neck Squamous Cell Carcinoma After Radiotherapy
NCT07545967 · ClinicalTrials.gov ↗ · Head and Neck Squamous Cell Carcinoma HNSCC
|
Phase 1 |
Recruiting |
West China Hospital |
China |
|
A Retrospective Clinical Study on the First-line Maintenance Treatment of PTCL With Chidamide.
|
Observational |
Recruiting |
The First Affiliated Hospital with Nanjing Medical University |
China |
Chidamide, Venetoclax, and Azacitidine for Newly Diagnosed Acute Myeloid Leukemia
NCT06386302 · ClinicalTrials.gov ↗ · AML, Acute Myeloid Leukemia
|
Not applicable |
Recruiting |
Institute of Hematology & Blood Diseases Hospital, China |
China |
Chidamide Combined With Brentuximab Vedotin Regimen for CD30+ PTCL Patients
NCT07074457 · ClinicalTrials.gov ↗ · CD30+ Peripheral T-cell Lymphoma
|
Not applicable |
Recruiting |
The First Affiliated Hospital of Soochow University |
China |
An Open-label, Single-arm, Multicenter Phase II Clinical Study of Azacitidine, Chidamide Combined With PD-1 Monoclonal Antibody in the Treatment of Refractory/Relapsed Peripheral T-cell Lymphoma.
NCT07598578 · ClinicalTrials.gov ↗ · Peripheral T-Cell Lymphoma Refractory
|
Early Phase 1 |
Recruiting |
Second Affiliated Hospital of Soochow University |
China |
Exploration of Dalpiciclib Plus HDACi in HR+/HER2- Advanced Breast Cancer After Failure of CDK4/6 Inhibitor
NCT06556862 · ClinicalTrials.gov ↗ · HR+/HER2- Advanced Breast Cancer
|
Phase 2 |
Not yet open |
Beijing 302 Hospital |
China |
Chidamide+Decitabine Plus Anti-PD-1 Antibody for Patients With R/R cHL Who Are Transplant-ineligible or Refused Transplant.
NCT06563778 · ClinicalTrials.gov ↗ · Ineligible Or Refused Transplant Patients With Classical Hodgkin Lymphoma
|
Phase 2 |
Not yet open |
Chinese PLA General Hospital |
China |
A Prospective, Randomized, Open, Phase II Clinical Study of Chidamide in Combination with Camrelizumab and Apatinib for Advanced Esophageal Cancer
NCT06745193 · ClinicalTrials.gov ↗ · Advanced Esophageal Carcinoma
|
Phase 2 |
Not yet open |
Peking University |
China |
Chidamide Monotherapy for Intermediate-to-High-Risk Myelodysplastic Syndromes
NCT07616336 · ClinicalTrials.gov ↗ · Myelodysplastic Syndromes
|
Phase 2 |
Not yet open |
Zhongshan Hospital (Xiamen), Fudan University |
China |
The Efficacy of CAPCT in Patients With PTCL
NCT07746245 · ClinicalTrials.gov ↗ · Peripheral T-Cell Lymphoma
|
Phase 2 |
Not yet open |
The First Affiliated Hospital with Nanjing Medical University |
China |
|
Chidamide Combined With Benmelstobart, Nab-paclitaxel, and SBRT as Second-Line Treatment for Advanced BTC
|
Phase 2 |
Not yet open |
The Affiliated Nanjing Drum Tower Hospital of Nanjing University Medical School |
China |
Prophylactic Strategies for Mitigating Central Nervous System Relapse in Diffuse Large B-Cell Lymphoma
NCT07917624 · ClinicalTrials.gov ↗ · Diffuse Large B-Cell Lymphoma (DLBCL)
|
Phase 2 |
Not yet open |
Cancer Institute and Hospital, Chinese Academy of Medical Sciences |
China |
A Safety and Efficacy Trial of Chidamide Combined With NKG2D CAR-NK Cell Therapy for Reducing the HIV Viral Reservoir
NCT07577986 · ClinicalTrials.gov ↗ · HIV (Human Immunodeficiency Virus)
|
Phase 1/2 |
Not yet open |
First Affiliated Hospital of Zhejiang University |
China |
Lisaftoclax Plus Chidamide and Rituximab in Relapsed or Refractory Diffuse Large B-cell Lymphoma
NCT07601607 · ClinicalTrials.gov ↗ · Relapsed or Refractory Diffuse Large B-Cell Lymphoma (R/R DLBCL)
|
Phase 1/2 |
Not yet open |
Sun Yat-sen University |
China |
AC-CHOP Versus CHOP in Patients With Previously Untreated PTCL-TFH
NCT05678933 · ClinicalTrials.gov ↗ · Peripheral T-cell Lymphoma Targeted Therapy
|
Phase 3 |
By invitation |
Tianjin Medical University Cancer Institute and Hospital |
China |
|
Evaluating the Efficacy of Chidamide in the Treatment of Initial Unresectable Metastatic Colorectal Cancer With High Expression of SULF1
|
Phase 2/3 |
By invitation |
Sir Run Run Shaw Hospital |
China |
Clinical Study of Mitoxantrone Hydrochloride Liposome Injection vs. Chidamide in Patients With Relapsed/Refractory PTCL
NCT04668690 · ClinicalTrials.gov ↗ · Peripheral T Cell Lymphoma
|
Phase 3 |
Active, closed |
CSPC ZhongQi Pharmaceutical Technology Co., Ltd |
China |
Study Comparing Investigational Drug HBI-8000 + Nivolumab vs. Placebo + Nivolumab in Patients With Advanced Melanoma
NCT04674683 · Unresectable or Metastatic Melanoma, Progressive Brain Metastasis
|
Phase 3 |
Active, closed |
HUYABIO International, LLC |
UK, USA, Germany, France, Spain, Italy, Belgium, Austria, Czechia, Brazil, Japan, South Korea, Singapore, Australia |
A Clinical Study Assessing the Efficacy of Chidamide for CD30-positive Peripheral T-cell Lymphoma (PTCL).
NCT06550336 · ClinicalTrials.gov ↗ · Peripheral T Cell Lymphoma
|
Phase 2 |
Active, closed |
The First Hospital of Jilin University |
China |
|
Efficacy and Safety of Chidamide in CBF Leukemia
|
Phase 1/2 |
Active, closed |
Institute of Hematology & Blood Diseases Hospital, China |
China |