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Compound · clinical trials

Liposome-encapsulated Daunorubicin-Cytarabine clinical trials

Also listed in trial records as CPX 351, CPX351, Vyxeos
Source: ClinicalTrials.gov, U.S. National Library of Medicine — the 5 trials in our Israel, Canada, Mexico, Germany, Austria and Australia registers that name Liposome-encapsulated Daunorubicin-Cytarabine as an intervention. Synced 28 Sep 2026
5Current trials
2Recruiting now
5Lead sponsors
6Country registers
Maintained by Sreepriya Prasannan
MSc Digital Transformation of Life Sciences (Innopharma Education / Griffith College); MSc & BSc Botany HSE Spark Ignite 2026 โ€” Top 14 finalist
Compiled from ClinicalTrials.gov registry records ยท Last verified ยท Editorial standards
At a glance

Liposome-encapsulated Daunorubicin-Cytarabine is named as an intervention in 5 current clinical trials in our Israel, Canada, Mexico, Germany, Austria and Australia registers. 2 are recruiting patients now. The most common phase is Phase 2. The sponsor with the most trials is University of Ulm (1). The most-studied condition is Acute Myeloid Leukemia.

Trials by status

  • Recruiting240%
  • Active, closed360%

Trials by phase

  • Phase 2360%
  • Phase 3240%
01

Clinical trials of Liposome-encapsulated Daunorubicin-Cytarabine

5 trials
StudyPhaseStatusLead sponsorRegisters
A Study to Compare Standard Chemotherapy to Therapy With CPX-351 and/or Gilteritinib for Patients With Newly Diagnosed AML With or Without FLT3 Mutations
NCT04293562 · ClinicalTrials.gov ↗ · Acute Myeloid Leukemia
Phase 3 Recruiting Children's Oncology Group Canada, Mexico, Australia, Israel
Testing New Therapies for Patients With Acute Myeloid Leukemia Who Are Newly Diagnosed and Have Not Yet Started Treatment (A MyeloMATCH Treatment Trial)
NCT05554406 · ClinicalTrials.gov ↗ · Acute Myeloid Leukemia, Acute Myeloid Leukemia Arising From Previous Myelodysplastic/Myeloproliferative Neoplasm, Acute Myeloid Leukemia Post Cytotoxic Therapy
Phase 2 Recruiting National Cancer Institute (NCI) Canada, Mexico, Israel
Study of Standard Intensive Chemotherapy Versus Intensive Chemotherapy With CPX-351 in Adult Patients With Newly Diagnosed AML and Intermediate- or Adverse Genetics
NCT03897127 · ClinicalTrials.gov ↗ · Acute Myeloid Leukemia
Phase 3 Active, closed University of Ulm Germany, Austria
Venetoclax + Azacitidine vs. Induction Chemotherapy in AML
NCT04801797 · ClinicalTrials.gov ↗ · Acute Myeloid Leukemia
Phase 2 Active, closed Massachusetts General Hospital Israel
Vyxeos for Induction of Low- or Intermediate-risk.
NCT05599360 · ClinicalTrials.gov ↗ · Leukemia, Myeloid, Acute
Phase 2 Active, closed Shaare Zedek Medical Center Israel

Registers list studies that are recruiting, about to open, active but closed to enrolment, or enrolling by invitation. The UK and USA registers cover industry-sponsored studies only. Trial titles and statuses are copied from the registry as published.

02

Conditions studied with Liposome-encapsulated Daunorubicin-Cytarabine

5 conditions
Acute Myeloid Leukemia4Acute Myeloid Leukemia Arising From Previous Myelodysplastic/Myeloproliferative Neoplasm1Acute Myeloid Leukemia Post Cytotoxic Therapy1Acute Myeloid Leukemia, Myelodysplasia-Related1Leukemia, Myeloid, Acute1
03

Sponsors

lead sponsor per trial
Lead sponsorTrials
University of Ulm1
Children's Oncology Group1
National Cancer Institute (NCI)1
Shaare Zedek Medical Center1
Massachusetts General Hospital1
04

By country register

RegisterTrialsRecruiting
Clinical trials in Israel42
Clinical trials in Canada22
Clinical trials in Mexico22
Clinical trials in Germany10
Clinical trials in Austria10
Clinical trials in Australia11

A trial with sites in more than one country appears in each of those registers.

05

Related compounds

06

Questions about Liposome-encapsulated Daunorubicin-Cytarabine trials

How many clinical trials are testing Liposome-encapsulated Daunorubicin-Cytarabine?

5 current trials in our Israel, Canada, Mexico, Germany, Austria and Australia registers name Liposome-encapsulated Daunorubicin-Cytarabine (also registered as CPX 351) as a drug or biological intervention, as of the registry sync on 28 September 2026. Completed and withdrawn studies are not counted.

Are Liposome-encapsulated Daunorubicin-Cytarabine trials recruiting patients?

Yes. 2 of the 5 trials are recruiting: 2 with sites in Israel, 2 with sites in Canada, 2 with sites in Mexico and 1 with sites in Australia. Eligibility and site contacts are on each trial's record. Only the study team can confirm whether a patient is eligible.

Who sponsors Liposome-encapsulated Daunorubicin-Cytarabine clinical trials?

University of Ulm (1), Children's Oncology Group (1), National Cancer Institute (NCI) (1) and Shaare Zedek Medical Center (1), among 5 lead sponsors in total. The number in brackets is how many trials each organisation leads.

Where does this information come from?

Every trial, status, phase and sponsor on this page is copied from public ClinicalTrials.gov records by a daily sync. Nothing here describes how Liposome-encapsulated Daunorubicin-Cytarabine works or whether it is effective, and it is not medical advice.

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How this page is built

Everything on this page is copied from public ClinicalTrials.gov registry records โ€” it is not written from memory, and nothing here describes how Liposome-encapsulated Daunorubicin-Cytarabine works or whether it is effective. Each trial links to its own record so you can check it yourself.

This page is built automatically: a daily sync job reads the registry records behind our country trial registers, collects every trial that lists Liposome-encapsulated Daunorubicin-Cytarabine (or a registered synonym) as a drug or biological intervention, and tabulates the registry fields directly. Placebos and generic comparators are excluded. There is no AI drafting and no per-compound editorial pass, and the page has not been clinically reviewed. The “last verified” date above is the timestamp of that sync, not a review date. Our general editorial approach is described in our editorial standards and corrections policy. The ClinicalTrials.gov data on this page was last retrieved on 28 Sep 2026.

Please verify before you rely on this. This page is general information for life-science and pharmaceutical professionals. It is not medical advice, and it has not been reviewed by a clinician โ€” our editorial team holds life-science qualifications, not clinical ones. It is not exhaustive and may not reflect the most recent label change. Always check the official prescribing information (US Prescribing Information or EU SmPC) and speak to your doctor or pharmacist before acting on anything here. Drugs in the same class are not automatically interchangeable, and approvals, brand names and indications differ between the US, the EU/Ireland (EMA/HPRA) and other regions. Spotted an error? Tell us โ€” we correct promptly and log it.