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Trackers› Clinical trials› Multiple Sclerosis
Clinical trial register · France

Multiple Sclerosis Trials in France, 2026

Every study on the ClinicalTrials.gov registry that lists a site in France and is open, about to open, active-but-closed, or enrolling by invitation. Filter it, cite it, and take it away as a file.

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Source: ClinicalTrials.gov, U.S. National Library of Medicine. Complete coverage — all 9714 matching records held by the registry are in this view. Synced 11 Nov 2026, 03:18 UTC
9714
Studies in scope
all four open statuses
6038
Recruiting now
open to new participants
1027
Lead sponsors
across recruiting studies
Top sites
Lille 16 Bordeaux 12 Clermont-Ferrand 12 Paris 10 Caen 9
Narrow the registerReset
Recruitment status
Phase
Lead sponsor
Hoffmann-La Roche5 Assistance Publique Hopitaux De Marseille5 Nantes University Hospital3 University Hospital, Lille3 University Hospital, Bordeaux3 Assistance Publique - Hôpitaux de Paris3 Centre Hospitalier Universitaire de Nice3 Sanofi3 Rennes University Hospital3 Fondation Ophtalmologique Adolphe de Rothschild2 Central Hospital, Nancy, France2 Centre Hospitalier Universitaire de Nīmes2 University Hospital, Toulouse2 University Hospital, Clermont-Ferrand2 EDMUS Foundation2 Centre Hospitalier de Gonesse2 University Hospital, Strasbourg, France2 Institut National de la Santé Et de la Recherche Médicale, France2 ÖSSUR France1 Immunic AG1 Poitiers University Hospital1 University Hospital, Caen1 Centre Hospitalier Universitaire de Liege1 Ad scientiam1 University Hospital, Montpellier1 Otto Bock France SNC1 Juno Therapeutics, Inc., a Bristol-Myers Squibb Company1 SYSNAV1 Lille Catholic University1 Novartis Pharmaceuticals1 University Hospital, Grenoble1
Site location
Lille16 Bordeaux12 Clermont-Ferrand12 Paris10 Caen9 Nice9 Créteil8 Nancy7 Marseille7 Lyon6 Grenoble6 Dijon6 Nantes5 Besançon5 Gonesse5 Brest4 Bron4 Rouen4 Strasbourg4 Rennes4 Nîmes3 Lomme3 Montpellier3 Toulouse3 Bayonne2 La Tronche2 Amiens2 Limoges2 Poissy2 Calais2 Colmar2 Hérouville-Saint-Clair1 La Membrolle-sur-Choisille1 Amiens Cedex11 Orsay1 Poitiers1 Libourne1 Clamart1 Berck1 Gaillac-Toulza1 Garches1 Cergy-Pontoise1 Arras1 Lens1 Le Kremlin-Bicêtre1 Haguenau1 Metz1 Mulhouse1 Reims1 Angers1 Chartres1 Saint-Herblain1 Ars-Laquenexy1
All 53 locations
Target enrolment
to

Multiple Sclerosis trials in France

62 of 9714 studies
Download
Status
Study
Lead sponsor
Phase
Enrol
Sites in France
Start
Not yet open
Neurogenetics and Multi-omics of Neuroinflammatory Diseases in Multiplex Families to Improve Patients Health
NCT07902479Multiple Sclerosis, Neuromyelitis Optica Spectrum Disorder, MOG Antibody-Associated Disease, Demyelinating Autoimmune Diseases, CNS
Institut National de la Santé Et de la Recherche Médicale, France
Not applicable
500
Bron, Nantes, Nice, Paris, Rennes
2026-11
Not yet open
University Hospital, Toulouse
Phase 4
160
Besançon, Bordeaux, Caen, Clermont-Ferrand, Créteil, Dijon, Grenoble, Libourne
2026-10-20
Recruiting
University Hospital, Lille
Observational
115
Lille
2026-10-12
Not yet open
University Hospital, Strasbourg, France
Not applicable
136
Colmar, Dijon, Haguenau, Metz, Mulhouse, Nancy, Reims, Strasbourg
2026-09-01
Recruiting
University Hospital, Caen
Observational
150
Caen, Lille, Rouen
2026-06-10
Not yet open
Internuclear Ophthalmoplegia and Multiple Sclerosis: a Multicenter Retrospective Study
NCT07560995Multiple Sclerosis, Internuclear Ophthalmoplegia
University Hospital, Strasbourg, France
Observational
200
Strasbourg
2026-05
Recruiting
Otto Bock France SNC
Not applicable
77
Berck, Créteil, Dijon, Gaillac-Toulza, Garches, Lomme, Lyon, Nice
2026-03-30
Recruiting
Assistance Publique - Hôpitaux de Paris
Observational
57
Paris
2026-03-18
Recruiting
SYSNAV
Observational
30
Lille
2026-03-16
Recruiting
University Hospital, Grenoble
Not applicable
160
Grenoble
2026-01-28
Recruiting
Assistance Publique - Hôpitaux de Paris
Not applicable
41
Lyon, Paris, Rennes, Toulouse
2025-12-16
Not yet open
Assistance Publique Hopitaux De Marseille
Not applicable
272
Montpellier
2025-12-01
Active, closed
Hoffmann-La Roche
Phase 2
193
Nantes, Nîmes
2025-11-13
Recruiting
ÖSSUR France
Not applicable
34
Hérouville-Saint-Clair, La Membrolle-sur-Choisille
2025-10-13
Recruiting
Central Hospital, Nancy, France
Observational
100
Ars-Laquenexy, Nancy
2025-09-01
Recruiting
Predictive Value of the Optic Nerve Involvement in Clinically Isolated Syndrome
NCT06455332Clinically Isolated Syndrome, Multiple Sclerosis
University Hospital, Lille
Not applicable
200
Lille
2025-07-17
Not yet open
Screening for Cognitive Disorders in Multiple Sclerosis
NCT07030036Multiple Sclerosis, Cognitive Dysfunction, Neuropsychological Tests, Quality of Life
Centre Hospitalier de Gonesse
Observational
60
Gonesse
2025-07-15
Not yet open
Centre Hospitalier de Gonesse
Observational
10
Gonesse
2025-06-15
Recruiting
The Role of Cytokines and Regulatory T Lymphocytes in Migraine Pathophysiology.
NCT06426316Migraine Disorders, Pain, Autoimmune Diseases, Multiple Sclerosis
DrugBlood test
University Hospital, Clermont-Ferrand
Not applicable
396
Clermont-Ferrand
2025-06-02
Recruiting
Integrating Metabolism, Connectivity, and Mesoscale Imaging at Ultra-high Field to Decipher Mechanisms of Resilience and Neurodegeneration in Neurological Diseases and Healthy Aging
NCT07202494Multiple Sclerosis, Neuromyelitis Optica Spectrum Disorders, Myelin Oligodendrocyte Glycoprotein Antibody-Associated Disease (MOGAD), Alzheimer Disease
Assistance Publique Hopitaux De Marseille
Observational
700
Marseille
2025-05-19
Recruiting
Interest of a Musical Intervention on Stress Induced During Botulinum Toxin Injections in Spasticity (MUSIBOT)
NCT06920524Stroke, Multiple Sclerosis, Spinal Cord Injury, Head Trauma Injury
University Hospital, Clermont-Ferrand
Not applicable
80
Clermont-Ferrand
2025-04-25
Recruiting
Rennes University Hospital
Phase 1
10
Créteil, Rennes
2025-03-06
Recruiting
Hoffmann-La Roche
Phase 3
500
Amiens Cedex1, Bayonne, Besançon, Bordeaux, Brest, Bron, Caen, Clermont-Ferrand
2024-12-13
Recruiting
Fondation Ophtalmologique Adolphe de Rothschild
Observational
196
Paris
2024-07-31
Active, closed
Juno Therapeutics, Inc., a Bristol-Myers Squibb Company
Phase 1
120
Lille, Paris
2024-03-28
Not yet open
Ifenprodil as a ReMyelinating repurpOsed Drug in Multiple Sclerosis
NCT06330077Multiple Sclerosis, Remitting Relapsing Multiple Sclerosis
Assistance Publique - Hôpitaux de Paris
Phase 2
60
Bron, Paris
2024-03
Active, closed
Sanofi
Phase 3
943
Créteil, Gonesse, La Tronche, Lille, Nancy, Nice, Orsay, Paris
2023-12-27
Active, closed
Sanofi
Phase 3
1,655
Calais, Colmar, La Tronche, Lille, Nice, Saint-Herblain
2023-12-13
Recruiting
University Hospital, Toulouse
Observational
400
Toulouse
2023-12-04
Recruiting
University Hospital, Bordeaux
Not applicable
160
Bordeaux
2023-12-04
Active, closed
Fondation Ophtalmologique Adolphe de Rothschild
Phase 3
244
Créteil, Gonesse, Grenoble, Limoges, Lyon, Nice, Paris, Poissy
2023-11-09
Active, closed
Ad scientiam
Not applicable
336
Lille, Lomme, Marseille, Nice, Rouen
2023-09-22
Recruiting
University Hospital, Montpellier
Not applicable
400
Montpellier
2023-09-11
Recruiting
University Hospital, Bordeaux
Not applicable
60
Bordeaux
2023-08-02
Recruiting
Assistance Publique Hopitaux De Marseille
Not applicable
50
Marseille
2023-06-16
Recruiting
RItuximab Versus Ocrelizumab in Relapsing-remitting Multiple Sclerosis.
NCT05758831Multiple Sclerosis, Relapsing-remitting Multiple Sclerosis
Rennes University Hospital
Phase 3
386
Lyon, Brest, Caen, Cergy-Pontoise, Clermont-Ferrand, Gonesse, Lille, Limoges
2023-06-01
Recruiting
MRI Biomarkers Predictive of Disability Progression in Patients With Multiple Sclerosis
NCT05491031Multiple Sclerosis, Magnetic Resonance Spectroscopy
Poitiers University Hospital
Not applicable
50
Poitiers
2023-04-25
Recruiting
Diagnostic Value of eVOG
NCT05776511Multiple Sclerosis, Radiologically Isolated Syndrome, White Matter Lesions
Centre Hospitalier Universitaire de Nice
Not applicable
150
Nice
2023-04-07
Recruiting
Nantes University Hospital
Observational
100
Nantes
2023-04-03
Active, closed
OFSEP Very High Definition Cohort
NCT05622643Multiple Sclerosis
EDMUS Foundation
Observational
300
Lyon, Nancy, Nîmes, Rennes, Strasbourg
2023-01-19
Active, closed
Hoffmann-La Roche
Phase 3
1,300
Caen, Nancy, Bordeaux, Bron, Clermont-Ferrand, Lille, Nice, Poissy
2022-05-03
Recruiting
RIS International Cohort
NCT05388331Multiple Sclerosis, Radiologically Isolated Syndrome
Centre Hospitalier Universitaire de Nice
Observational
1,000
Nice
2022-04-15
Active, closed
Centre Hospitalier Universitaire de Nice
Phase 3
72
Amiens, Bayonne, Bordeaux, Caen, Clermont-Ferrand, Lille, Lyon, Marseille
2022-03-08
Recruiting
Nantes University Hospital
Not applicable
130
Nantes
2022-01-24
Recruiting
Transcutaneous Tibial Neuro-stimulation to Improve Voiding Dysfunction in Multiple Sclerosis.
NCT04573673Multiple Sclerosis, Lower Urinary Tract Symptoms
University Hospital, Lille
Not applicable
68
Lille
2021-12-01
Active, closed
Immunic AG
Phase 3
1,121
2021-11-18
Recruiting
Lille Catholic University
Not applicable
150
Arras, Lens, Lille, Lomme, Rouen
2021-10-08
Recruiting
Pathogenicity of B and CD4 T Cell Subsets in Multiple Sclerosis
NCT04798651Multiple Sclerosis, Clinically Isolated Syndrome
DrugBlood sample
University Hospital, Bordeaux
Not applicable
150
Bordeaux
2021-09-30
Active, closed
Sanofi
Phase 2
129
Calais
2021-06-07
Active, closed
Centre Hospitalier Universitaire de Liege
Not applicable
80
Clamart, Paris
2021-03-09
Recruiting
Nantes University Hospital
Phase 1
7
Nantes
2021-01-26
Active, closed
Hoffmann-La Roche
Phase 3
769
Besançon, Brest, Caen, Clermont-Ferrand, Lille, Nancy, Strasbourg
2020-12-03
Active, closed
Hoffmann-La Roche
Phase 3
864
Bordeaux, Clermont-Ferrand, Lille, Rouen
2020-11-26
Active, closed
Centre Hospitalier Universitaire de Nīmes
Observational
200
Nîmes
2019-06-25
Active, closed
Centre Hospitalier Universitaire de Nīmes
Observational
1,150
Amiens, Besançon, Bordeaux, Caen, Clermont-Ferrand, Créteil, Dijon, Grenoble
2019-05-22
Active, closed
Rennes University Hospital
Phase 3
250
Angers, Bordeaux, Brest, Chartres, Clermont-Ferrand, Créteil, Dijon, Grenoble
2019-01-24
Active, closed
Assistance Publique Hopitaux De Marseille
Not applicable
32
Marseille
2018-12-20
Active, closed
OFSEP High Definition Cohort
NCT03603457Multiple Sclerosis
EDMUS Foundation
Observational
2,842
Besançon, Bordeaux, Caen, Clermont-Ferrand, Créteil, Dijon, Grenoble, Lille
2018-07-10
Active, closed
Institut National de la Santé Et de la Recherche Médicale, France
Observational
120
Paris
2018-02-06
Active, closed
Assistance Publique Hopitaux De Marseille
Not applicable
70
Marseille
2017-10-02
Active, closed
Novartis Pharmaceuticals
Phase 3
240
Bordeaux, Le Kremlin-Bicêtre, Marseille, Montpellier, Toulouse
2013-07-26
Recruiting
Lorraine Registry of Multiple Sclerosis
NCT02883335Multiple Sclerosis
Central Hospital, Nancy, France
Observational
6,000
Nancy
2003-05
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Cite this view

Priya Life Science (2026). Clinical trial register: studies with a French investigative site, filtered. Derived from ClinicalTrials.gov. Retrieved 12 November 2026. https://priyalifescience.com/clinical-trials-france/condition/multiple-sclerosis

Query this register directly
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About this register

This register is built from ClinicalTrials.gov, the trial registry run by the U.S. National Library of Medicine. It includes every study on the registry that lists at least one investigative site in France and is recruiting, not yet recruiting, active but no longer recruiting, or enrolling by invitation: 9,714 studies in total at the last sync on 11 Nov 2026, 03:18 UTC. The full list can be downloaded as CSV or queried as JSON through the register API.

This page shows the 62 of those studies listing the condition Multiple Sclerosis.

How many Multiple Sclerosis trials are recruiting in France?

32 of the 62 studies on this page are recruiting new participants as of the 11 Nov 2026, 03:18 UTC sync. A further 8 have not yet opened recruitment, 22 are active but closed to new participants, and 0 are enrolling by invitation only. Eligibility for any study is decided by its study team.

Summary by phase

Studies by phase (Multiple Sclerosis), 62 studies
PhaseStudiesRecruitingShare
Not applicable241738.7%
Observational191130.6%
Phase 312219.4%
Phase 1324.8%
Phase 2304.8%
Phase 4101.6%

Most active sponsors

Lead sponsors with the most studies (Multiple Sclerosis)
Lead sponsorStudiesRecruiting
Assistance Publique Hopitaux De Marseille52
Hoffmann-La Roche51
Assistance Publique - Hôpitaux de Paris32
Centre Hospitalier Universitaire de Nice32
Nantes University Hospital33
Rennes University Hospital32
Sanofi30
University Hospital, Bordeaux33
University Hospital, Lille33
Central Hospital, Nancy, France22
Listing here is informational and not medical advice; eligibility is determined by each study team. See also the Ireland, UK, EU, USA and China registers.