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Priya Life Science Compound trial record
Compound · clinical trials

Avonex clinical trials

Also listed in trial records as Interferon beta-1a, IFN-β1a, BG9418, Interferon beta type 1a, Rebif
Source: ClinicalTrials.gov, U.S. National Library of Medicine — the 6 trials in our Germany, Spain, Australia, France, Italy, USA, Ireland, Netherlands, Belgium, Switzerland, Czechia, Portugal, Canada, Israel, UK, Turkey, India, Japan, Poland, Austria, Brazil, Mexico and Sweden registers that name Avonex as an intervention. Synced 11 Nov 2026
6Current trials
3Recruiting now
5Lead sponsors
23Country registers
At a glance

Avonex is named as an intervention in 6 current clinical trials in our Germany, Spain, Australia, France, Italy, USA, Ireland, Netherlands, Belgium, Switzerland, Czechia, Portugal, Canada, Israel, UK, Turkey, India, Japan, Poland, Austria, Brazil, Mexico and Sweden registers. 3 are recruiting patients now. The most common phase is Phase 3. The sponsor with the most trials is Biogen (2). The most-studied condition is Multiple Sclerosis.

Where Avonex is approved

All regulators →

Of the three regulators tracked here, the first to approve Avonex was the US, on 17 May 1996. It is approved in 3 of the 3 regulators tracked here.

USUnited States (FDA)
17 May 1996
Avonex
BLA103628 on Drugs@FDA
First original NDA/BLA approval
EUEuropean Union (EMA)
13 Mar 1997
Avonex
EMA product page
First centralised authorisation
CACanada (Health Canada)
5 Feb 1998
Rebif
Notice of Compliance 2996
First new-drug NOC

From the regulators' own registers: FDA Drugs@FDA, the EMA medicines list and Health Canada's Notice of Compliance database. Dates are the first listed approval of a product containing only this substance; combination products and nationally authorised EU medicines are not counted.

What health systems spend on Avonex

All medicines →
ENNHS England
Not dispensed in the community in England in the last 12 months under this name
Net ingredient cost, community prescriptions
USUS Medicaid
$61.6m
6,775 prescriptions in 2025 · Avonex, Rebif, Rebif Rebidose
-20% on 2024
Amount Medicaid reimbursed, before rebates

From NHSBSA Prescription Cost Analysis (Open Government Licence v3.0) and CMS State Drug Utilization Data. Both are gross amounts: neither system publishes its discounts or rebates per drug. Products combining several substances are not counted here.

NICE appraisals of Avonex

All NICE appraisals →

NICE, which decides whether the NHS in England should fund new medicines, has published 1 technology appraisal of Avonex. 1 is current, and 1 of it recommends it for at least some patients.

AppraisalNICE recommendationPublishedStatus
Beta interferons and glatiramer acetate for treating multiple sclerosis
NICE TA527
Recommended Not recommended27 Jun 2018Current

NICE decisions apply to the NHS in England. In Ireland the HSE decides on reimbursement, advised by the National Centre for Pharmacoeconomics. Titles, categories and dates link to the guidance on nice.org.uk. © NICE 2026 technology appraisal guidance. Available from www.nice.org.uk/guidance. All rights reserved. Subject to Notice of rights. NICE guidance is prepared for the National Health Service in England. All NICE guidance is subject to regular review and may be updated or withdrawn. NICE accepts no responsibility for the use of its content in this product/publication.

Patient leaflets for Avonex

The package leaflet is the official guide for patients that comes with every medicine. These links go to the regulators that publish it.

  • EU
    European Union: Avonex, Rebif
    EMA product information: package leaflet and summary of product characteristics in every EU language.
  • UK
    United Kingdom: Search MHRA Products
    Patient information leaflets and SmPCs for UK-licensed products.
  • US
    United States: Search DailyMed
    FDA-approved labels, including patient and medication guides.

Leaflets differ between brands and countries; always read the one that comes with your own medicine. This is regulatory information, not medical advice.

Trials by status

  • Recruiting350%
  • Active, closed350%

Trials by phase

  • Phase 3350%
  • Observational233%
  • Phase 2117%
01

Clinical trials of Avonex

6 trials
StudyPhaseStatusLead sponsorRegisters
Randomized, Embedded, Multifactorial Adaptive Platform Trial for Community- Acquired Pneumonia
NCT02735707 · Respiratory Tract Diseases, Influenza (Pandemic), Influenza
Phase 3 Recruiting UMC Utrecht Ireland, India, Germany, France, Spain, Italy, Netherlands, Belgium, Switzerland, Czechia, Portugal, Canada, Japan, Australia, Israel
Nivolumab in Children and Adults With Nasopharyngeal Carcinoma
NCT06019130 · ClinicalTrials.gov ↗ · Nasopharyngeal Carcinoma, Nasopharyngeal Cancer, Nasopharyngeal Neoplasms
Phase 2 Recruiting German Society for Pediatric Oncology and Hematology GPOH gGmbH Germany
Pregnancy Exposure Registry for Vumerity (Diroximel Fumarate)
NCT05658497 · Multiple Sclerosis
Observational Recruiting Biogen Ireland, UK, USA, Germany, Spain, Switzerland, Australia
Safety and Efficacy of Fingolimod in Pediatric Patients With Multiple Sclerosis
NCT01892722 · Multiple Sclerosis
Phase 3 Active, closed Novartis Pharmaceuticals UK, USA, Germany, France, Spain, Italy, Netherlands, Poland, Austria, Turkey, Canada, Brazil, Mexico, Australia
A Study to Evaluate the Safety, Tolerability, and Efficacy of BIIB017 (Peginterferon Beta-1a) in Pediatric Participants for the Treatment of Relapsing-Remitting Multiple Sclerosis
NCT03958877 · Multiple Sclerosis, Relapsing-Remitting
Phase 3 Active, closed Biogen USA, Germany, France, Spain, Italy, Belgium, Czechia, Portugal, Turkey, Australia, Israel
An Observational Study to Learn About the Interferon-beta Exposure of Pregnant Women During the Second and Third Trimester in Finland and Sweden
NCT06053749 · ClinicalTrials.gov ↗ · Multiple Sclerosis (MS)
Observational Active, closed Bayer Sweden

Registers list studies that are recruiting, about to open, active but closed to enrolment, or enrolling by invitation. The UK and USA registers cover industry-sponsored studies only. Trial titles and statuses are copied from the registry as published.

02

Conditions studied with Avonex

11 conditions
Multiple Sclerosis2Respiratory Tract Diseases1Influenza (Pandemic)1Influenza1Community Acquired Pneumonia1Nasopharyngeal Carcinoma1Nasopharyngeal Cancer1Nasopharyngeal Neoplasms1Nasopharynx Cancer1Multiple Sclerosis, Relapsing-Remitting1Multiple Sclerosis (MS)1
05

Related compounds

06

Questions about Avonex trials

How many clinical trials are testing Avonex?

6 current trials in our Germany, Spain, Australia, France, Italy, USA, Ireland, Netherlands, Belgium, Switzerland, Czechia, Portugal, Canada, Israel, UK, Turkey, India, Japan, Poland, Austria, Brazil, Mexico and Sweden registers name Avonex (also registered as Interferon beta-1a) as a drug or biological intervention, as of the registry sync on 11 November 2026. Completed and withdrawn studies are not counted.

Are Avonex trials recruiting patients?

Yes. 3 of the 6 trials are recruiting: 3 with sites in Germany, 2 with sites in Spain, 2 with sites in Australia, 1 with sites in France, 1 with sites in Italy, 1 with sites in USA, 2 with sites in Ireland, 1 with sites in Netherlands, 1 with sites in Belgium, 2 with sites in Switzerland, 1 with sites in Czechia, 1 with sites in Portugal, 1 with sites in Canada, 1 with sites in Israel, 1 with sites in UK, 1 with sites in India and 1 with sites in Japan. Eligibility and site contacts are on each trial's record. Only the study team can confirm whether a patient is eligible.

Who sponsors Avonex clinical trials?

Biogen (2), UMC Utrecht (1), Novartis Pharmaceuticals (1) and German Society for Pediatric Oncology and Hematology GPOH gGmbH (1), among 5 lead sponsors in total. The number in brackets is how many trials each organisation leads.

Are there Avonex clinical trials in Ireland?

Yes. 2 trials in our Ireland register (ClinicalTrials.gov). Some may be the same study registered in both. See the Irish clinical trials register for sites and contacts.

Where does this information come from?

Every trial, status, phase and sponsor on this page is copied from public ClinicalTrials.gov records by a daily sync. Nothing here describes how Avonex works or whether it is effective, and it is not medical advice.

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How this page is built

Everything on this page is copied from public ClinicalTrials.gov registry records — it is not written from memory, and nothing here describes how Avonex works or whether it is effective. Each trial links to its own record so you can check it yourself.

This page is built automatically: a daily sync job reads the registry records behind our country trial registers, collects every trial that lists Avonex (or a registered synonym) as a drug or biological intervention, and tabulates the registry fields directly. Placebos and generic comparators are excluded. There is no AI drafting and no per-compound editorial pass, and the page has not been clinically reviewed. The “last verified” date above is the timestamp of that sync, not a review date. Our general editorial approach is described in our editorial standards and corrections policy. The ClinicalTrials.gov data on this page was last retrieved on 11 Nov 2026. How every register is built: methodology · fixes we have made: corrections log.

Please verify before you rely on this. This page is general information for life-science and pharmaceutical professionals. It is not medical advice, and it has not been reviewed by a clinician — our editorial team holds life-science qualifications, not clinical ones. It is not exhaustive and may not reflect the most recent label change. Always check the official prescribing information (US Prescribing Information or EU SmPC) and speak to your doctor or pharmacist before acting on anything here. Drugs in the same class are not automatically interchangeable, and approvals, brand names and indications differ between the US, the EU/Ireland (EMA/HPRA) and other regions. Spotted an error? Tell us — we correct promptly and log it.