Aspirin clinical trials
Aspirin is named as an intervention in 99 current clinical trials in our China, France, Canada, South Korea, Denmark, Netherlands, Israel, India, Germany, Spain, Italy, Belgium, Switzerland, Japan, Poland, Sweden, Mexico, Egypt, Ireland, Portugal, Australia, Norway, Czechia, USA, Austria and Brazil registers. 67 are recruiting patients now. The most common phase is Phase 3. The sponsor with the most trials is Asan Medical Center (3). The most-studied condition is Coronary Artery Disease.
Where Aspirin is approved
All regulators →Of the three regulators tracked here, the first to approve Aspirin was the US, on 25 Jun 1965.
From the regulators' own registers: FDA Drugs@FDA, the EMA medicines list and Health Canada's Notice of Compliance database. Dates are the first listed approval of a product containing only this substance; combination products and nationally authorised EU medicines are not counted.
Aspirin patents and exclusivity
Expiry tracker →Protections still running for marketed products containing Aspirin, as listed by the regulators. Expired patents and exclusivities, and discontinued products, are not shown.
- 4 listed patents; the last listed expires 29 Sep 2032 (US 9226892).
Reproduced from the FDA Orange Book and Purple Book (checked 8 Nov 2026) and the European Commission's Union Register of medicinal products (CC BY 4.0; the EU expiry date is calculated exactly as the Commission's register displays it). Listed patents and dates are as submitted to or published by the regulator and may not reflect litigation, invalidation, settlements, lapsed fees or later extensions. This is not legal advice or a freedom-to-operate opinion, and it does not say when a generic or biosimilar will launch.
What health systems spend on Aspirin
All medicines →From NHSBSA Prescription Cost Analysis (Open Government Licence v3.0) and CMS State Drug Utilization Data. Both are gross amounts: neither system publishes its discounts or rebates per drug. Products combining several substances are not counted here.
How Aspirin works
All drug targets →- Cyclooxygenase inhibitor InhibitorTarget: Cyclooxygenase✓ In ChEMBL and the Guide to Pharmacology
- COVID-19Phase 3
- COVID-19–associated multisystem inflammatory syndrome in childrenPhase 3
- FatiguePhase 3
- HIV infectious diseasePhase 3
- Kawasaki diseasePhase 3
- Nasal congestionPhase 3
- Nasal polyposisPhase 3
- Orthomyxoviridae infectious diseasePhase 3
- ST Elevation Myocardial InfarctionPhase 3
- Visual lossPhase 3
Mechanisms and diseases from ChEMBL via the Open Targets Platform (release 26.09), ChEMBL record CHEMBL25, CC BY-SA 3.0. Targets checked against the IUPHAR/BPS Guide to PHARMACOLOGY (2026.3.1), ligand 4139, CC BY-SA 4.0. Trial phases are not approvals: approved uses are shown from the regulators' own records where we hold them.
Patient leaflets for Aspirin
The package leaflet is the official guide for patients that comes with every medicine. These links go to the regulators that publish it.
- IEIreland: 1 product on the HPRA listEach product record links to the HPRA, which publishes the leaflet and SmPC.
- UKUnited Kingdom: Search MHRA ProductsPatient information leaflets and SmPCs for UK-licensed products.
- USUnited States: Search DailyMedFDA-approved labels, including patient and medication guides.
Leaflets differ between brands and countries; always read the one that comes with your own medicine. This is regulatory information, not medical advice.
Reference identifiers for Aspirin
- ChEMBL
- CHEMBL25
- DrugBank
- DB00945
- PubChem CID
- 2244
- CAS number
- 50-78-2
- FDA UNII
- R16CO5Y76E
- Wikidata
- Q18216
- Wikipedia
- Aspirin
Codes that identify this medicine in other databases, from Wikidata (CC0), matched by its ChEMBL ID. The ATC code is the WHO classification of what the medicine is used for.
Trials by status
Trials by phase
Clinical trials of Aspirin
99 trialsRegisters list studies that are recruiting, about to open, active but closed to enrolment, or enrolling by invitation. The UK and USA registers cover industry-sponsored studies only. Trial titles and statuses are copied from the registry as published.
Aspirin across our data
Ireland · EU · USThe same active substance in our other registers, matched by its exact name. Each entry links to the register record it comes from.
Licensed in Ireland (HPRA)
1 single-substance product containing Aspirin on the HPRA medicines list.
- Aspirin 300mg Effervescent tabletsBayer Limited · PA1410/037/001 · Not marketed
Supply shortages
No entry for Aspirin in the EMA, FDA or German BfArM shortage lists we track.
Conditions studied with Aspirin
142 conditionsAll 142 conditions
| Condition (as registered) | Trials |
|---|---|
| Coronary Artery Disease | 8 |
| Ischemic Stroke | 7 |
| Atrial Fibrillation | 6 |
| Cerebral Infarction | 5 |
| Percutaneous Coronary Intervention | 5 |
| Cardiovascular Diseases | 5 |
| Acute Coronary Syndrome | 4 |
| Stroke | 4 |
| Aspirin | 3 |
| Acute Ischemic Stroke | 3 |
| Stroke, Ischemic | 3 |
| Pre-Eclampsia | 3 |
| Colorectal Cancer | 2 |
| Venous Thromboembolism | 2 |
| Multiple Myeloma | 2 |
| Kawasaki Disease | 2 |
| Preeclampsia | 2 |
| Chronic Coronary Syndrome | 2 |
| Acute Myocardial Infarction (AMI) | 2 |
| Percutaneous Coronary Intervention (PCI) | 2 |
| Peripheral Arterial Disease | 2 |
| Pregnancy Related | 2 |
| Atherosclerosis | 2 |
| NSTEMI - Non-ST Segment Elevation Myocardial Infarction (MI) | 2 |
| Ischemic Heart Disease | 2 |
| Cancer | 1 |
| Breast Cancer | 1 |
| Prostate Cancer | 1 |
| Respiratory Tract Diseases | 1 |
| Influenza (Pandemic) | 1 |
| Influenza | 1 |
| Community Acquired Pneumonia | 1 |
| Postpartum Period | 1 |
| Low Molecular Weight Heparin | 1 |
| Drug-drug Interaction | 1 |
| Intracerebral Haemorrhage | 1 |
| Tuberculous Meningitis | 1 |
| Pneumonia | 1 |
| In-stent Restenosis | 1 |
| Venous Thromboembolism (VTE) | 1 |
| Mitral Valve Repair Surgery | 1 |
| Aneurysmal Subarachnoid Hemorrhage (aSAH) | 1 |
| Delayed Cerebral Ischemia | 1 |
| Transient Ischemic Attack | 1 |
| Stroke, Acute | 1 |
| Moyomoya Disease | 1 |
| Aortic Regurgitation Disease | 1 |
| Immune Thrombocytopenia | 1 |
| CKD (Chronic Kidney Disease) Stage 5D | 1 |
| Acute Coronary Syndromes | 1 |
| Small Vessel Cerebrovascular Disease | 1 |
| White Matter Hyperintensity | 1 |
| Coronary Artery Aneurysm | 1 |
| Antiplatelet Drugs | 1 |
| Diabetic Angiopathies | 1 |
| Arterial Occlusive Diseases | 1 |
| Deep Vein Thrombosis | 1 |
| Iliac Vein Thrombosis | 1 |
| Iliac Vein Obstruction | 1 |
| Iliac Vein Stenosis | 1 |
| Cerebral Microbleeds | 1 |
| Connective Tissue Diseases | 1 |
| Protein S Deficiency | 1 |
| Interventional Cardiology | 1 |
| Thrombolysis | 1 |
| Chronic Coronary Disease | 1 |
| Large-Artery Atherosclerosis (Embolus/Thrombosis) | 1 |
| Covert Brain Infarction | 1 |
| Atrial Fibrillation (AF) | 1 |
| Oral Anticoagulation | 1 |
| P2Y12 Inhibitor | 1 |
| Sudden Sensorineural Hearing Loss | 1 |
| Metastatic Colorectal Cancer | 1 |
| Diabete Type 2 | 1 |
| Chronic Hypertension Complicating Pregnancy | 1 |
| Intrauterine Growth Restriction | 1 |
| ART | 1 |
| Atrial Appendage | 1 |
| Anticoagulants | 1 |
| Polycythemia Vera | 1 |
| Essential Thrombocythemia | 1 |
| Prefibrotic/Early Primary Myelofibrosis | 1 |
| JAK2 V617F | 1 |
| Transcatheter Aortic Valve Replacement | 1 |
| Type 2 Diabetes | 1 |
| Colon Cancer | 1 |
| Adjuvant Therapy | 1 |
| ST Elevation Myocardial Infarction | 1 |
| HIV-1 Infection | 1 |
| Heart Failure | 1 |
| Type 1 Diabetes | 1 |
| Kidney Failure | 1 |
| Drug Effect | 1 |
| Stable Coronary Artery Disease CAD | 1 |
| Antithrombotic Therapy | 1 |
| Percutaneous Coronary Interventions | 1 |
| Cardiovascular Prevention | 1 |
| Barrett Esophagus | 1 |
| Esophageal Adenocarcinoma | 1 |
| NSTEMI - Non-ST Segment Elevation MI | 1 |
| STEMI (ST Elevation MI) | 1 |
| Myocardial Infarction | 1 |
| Hip Fractures | 1 |
| Antiphospholipid Syndrome | 1 |
| Arterial Thrombosis | 1 |
| Intracranial Atherosclerosis | 1 |
| Cardiac Allograft Vasculopathy | 1 |
| Heart Transplant | 1 |
| Staphylococcus Aureus Endocarditis | 1 |
| Staphylococcus Aureus Septicemia | 1 |
| Staphylococcus Aureus Bloodstream Infection | 1 |
| Venous Thormboembolism | 1 |
| Vascular Surgery Patient with PAD / Carotid Stenosis | 1 |
| Intracerebral Hemorrhage | 1 |
| Coronary Artery Ectasia | 1 |
| Acute Coronary Syndromes (ACS) | 1 |
| STEMI - ST Elevation Myocardial Infarction | 1 |
| Hypertensive Disorders of Pregnancy | 1 |
| Gestational Hypertension | 1 |
| Intracranial Arteriosclerosis | 1 |
| Antiplatelet Agents | 1 |
| Perioperative Care | 1 |
| Stable Angina Pectoris | 1 |
| Valve Replacement Surgery | 1 |
| Healthy Adult Male | 1 |
| Gastric Cancer | 1 |
| Type 2 Diabetes Mellitus (T2DM) | 1 |
| Acute Coronary Syndrome (ACS) Undergoing Percutaneous Coronary Intervention (PCI) | 1 |
| High Bleeding Risk | 1 |
| Stenosis Artery | 1 |
| Sarcoma | 1 |
| Soft Tissue Sarcoma | 1 |
| Bone Sarcoma | 1 |
| Bone Metastases | 1 |
| Inflammatory Response | 1 |
| Inflammation | 1 |
| Sleep | 1 |
| Sleep Restriction | 1 |
| Lynch Syndrome I (Site-specific Colonic Cancer) | 1 |
| Periodontal Disease | 1 |
| Periodontitis (Stage 3) | 1 |
| Smoking Behaviors | 1 |
Sponsors
lead sponsor per trial+ 66 more sponsors in the trial list above.
By country register
A trial with sites in more than one country appears in each of those registers.
Related compounds
Questions about Aspirin trials
How many clinical trials are testing Aspirin?
99 current trials in our China, France, Canada, South Korea, Denmark, Netherlands, Israel, India, Germany, Spain, Italy, Belgium, Switzerland, Japan, Poland, Sweden, Mexico, Egypt, Ireland, Portugal, Australia, Norway, Czechia, USA, Austria and Brazil registers name Aspirin (also registered as Early, 2h) as a drug or biological intervention, as of the registry sync on 11 November 2026. Completed and withdrawn studies are not counted.
Are Aspirin trials recruiting patients?
Yes. 67 of the 99 trials are recruiting: 23 with sites in China, 11 with sites in France, 11 with sites in Canada, 8 with sites in South Korea, 6 with sites in Denmark, 4 with sites in Netherlands, 2 with sites in Israel, 3 with sites in India, 4 with sites in Germany, 3 with sites in Spain, 4 with sites in Italy, 4 with sites in Belgium, 3 with sites in Switzerland, 4 with sites in Japan, 4 with sites in Poland, 3 with sites in Sweden, 3 with sites in Mexico, 4 with sites in Egypt, 2 with sites in Ireland, 3 with sites in Portugal, 2 with sites in Australia, 1 with sites in Norway, 1 with sites in Czechia, 1 with sites in USA, 1 with sites in Austria and 1 with sites in Brazil. Eligibility and site contacts are on each trial's record. Only the study team can confirm whether a patient is eligible.
Who sponsors Aspirin clinical trials?
Asan Medical Center (3), Kafrelsheikh University (3), University of Calgary (2) and Fu Wai Hospital, Beijing, China (2), among 81 lead sponsors in total. The number in brackets is how many trials each organisation leads.
Are there Aspirin clinical trials in Ireland?
Yes. 3 trials in our Ireland register (ClinicalTrials.gov). Some may be the same study registered in both. See the Irish clinical trials register for sites and contacts.
Is Aspirin licensed in Ireland?
Yes. The HPRA medicines list includes 1 single-substance product containing Aspirin, for example Aspirin 300mg Effervescent tablets (Bayer Limited). A licence does not mean a product is currently marketed or reimbursed; see each product's record.
Is there a Aspirin shortage?
Not in the lists we track: Aspirin has no entry in the EMA, FDA or German BfArM shortage registers as of their latest sync.
Where does this information come from?
Every trial, status, phase and sponsor on this page is copied from public ClinicalTrials.gov records by a daily sync. Nothing here describes how Aspirin works or whether it is effective, and it is not medical advice.
How this page is built
Everything on this page is copied from public ClinicalTrials.gov registry records — it is not written from memory, and nothing here describes how Aspirin works or whether it is effective. Each trial links to its own record so you can check it yourself.
- ClinicalTrials.gov (U.S. National Library of Medicine) ↗ Trial IDs, titles, intervention names and synonyms, phase, overall status, lead sponsor and conditions for every trial on this page
This page is built automatically: a daily sync job reads the registry records behind our country trial registers, collects every trial that lists Aspirin (or a registered synonym) as a drug or biological intervention, and tabulates the registry fields directly. Placebos and generic comparators are excluded. There is no AI drafting and no per-compound editorial pass, and the page has not been clinically reviewed. The “last verified” date above is the timestamp of that sync, not a review date. Our general editorial approach is described in our editorial standards and corrections policy. The ClinicalTrials.gov data on this page was last retrieved on 11 Nov 2026. How every register is built: methodology · fixes we have made: corrections log.