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Compound · clinical trials

ATRA clinical trials

Source: ClinicalTrials.gov, U.S. National Library of Medicine — the 5 trials in our China and USA registers that name ATRA as an intervention. Synced 25 Sep 2026
5Current trials
2Recruiting now
5Lead sponsors
2Country registers
Maintained by Sreepriya Prasannan
MSc Digital Transformation of Life Sciences (Innopharma Education / Griffith College); MSc & BSc Botany HSE Spark Ignite 2026 โ€” Top 14 finalist
Compiled from ClinicalTrials.gov registry records ยท Last verified ยท Editorial standards
At a glance

ATRA is named as an intervention in 5 current clinical trials in our China and USA registers. 2 are recruiting patients now. The most common phase is Not applicable. The sponsor with the most trials is Quetzal Therapeutics (1). The most-studied condition is Acute Promyelocytic Leukemia (APL).

Trials by status

  • Recruiting240%
  • Not yet open240%
  • By invitation120%

Trials by phase

  • Not applicable240%
  • Phase 3120%
  • Phase 2120%
  • Phase 1/2120%
01

Clinical trials of ATRA

5 trials
StudyPhaseStatusLead sponsorRegisters
Pivotal Open-label Phase 3 Clinical Study of QTX-2101 in Adult Patients With Acute Promyelocytic Leukemia
NCT07504458 · Acute Promyelocytic Leukemia (APL), Acute Promyelocytic Leukaemia, Acute Promyelocytic Leukemia With PML-RARA
Phase 3 Recruiting Quetzal Therapeutics USA
A Study on the Efficacy and Safety of Oral All-trans Retinoic Acid Combined With Toripalimab in TNBC.
NCT06371274 · ClinicalTrials.gov ↗ · Triple-negative Breast Cancer
Not applicable Recruiting First Affiliated Hospital of Zhejiang University China
A Clinical Study on the Efficacy and Safety of All-trans Retinoic Acid Combined With VAC Regimen in the Treatment of Intermediate-to-high-risk Rhabdomyosarcoma
NCT07355855 · ClinicalTrials.gov ↗ · Rhabdomyosarcoma
Phase 2 Not yet open Fudan University China
Study of Tretinoin Capsules in Combination With Azacitidine and Venetoclax in Treatment Naรฏve Participants With Acute Myeloid Leukemia
NCT06841952 · ClinicalTrials.gov ↗ · AML, Adult
Not applicable Not yet open The First Affiliated Hospital of Soochow University China
Efficacy and Safety of ATO Plus ATRA in Nucleophosmin-1 Mutated Acute Myeloid Leukemia
NCT03031249 · ClinicalTrials.gov ↗ · AML
Phase 1/2 By invitation Institute of Hematology & Blood Diseases Hospital, China China

Registers list studies that are recruiting, about to open, active but closed to enrolment, or enrolling by invitation. The UK and USA registers cover industry-sponsored studies only. Trial titles and statuses are copied from the registry as published.

02

Conditions studied with ATRA

8 conditions
Acute Promyelocytic Leukemia (APL)1Acute Promyelocytic Leukaemia1Acute Promyelocytic Leukemia With PML-RARA1Acute Promyelocytic Leukemia With t(15;17)(q24.1;q21.2); PML-RARA1Triple-negative Breast Cancer1Rhabdomyosarcoma1AML, Adult1AML1
03

Sponsors

lead sponsor per trial
Lead sponsorTrials
Quetzal Therapeutics1
First Affiliated Hospital of Zhejiang University1
Fudan University1
The First Affiliated Hospital of Soochow University1
Institute of Hematology & Blood Diseases Hospital, China1
04

By country register

RegisterTrialsRecruiting
Clinical trials in China41
Clinical trials in USA11

A trial with sites in more than one country appears in each of those registers.

05

Related compounds

06

Questions about ATRA trials

How many clinical trials are testing ATRA?

5 current trials in our China and USA registers name ATRA as a drug or biological intervention, as of the registry sync on 25 September 2026. Completed and withdrawn studies are not counted.

Are ATRA trials recruiting patients?

Yes. 2 of the 5 trials are recruiting: 1 with sites in China and 1 with sites in USA. Eligibility and site contacts are on each trial's record. Only the study team can confirm whether a patient is eligible.

Who sponsors ATRA clinical trials?

Quetzal Therapeutics (1), First Affiliated Hospital of Zhejiang University (1), Fudan University (1) and The First Affiliated Hospital of Soochow University (1), among 5 lead sponsors in total. The number in brackets is how many trials each organisation leads.

Where does this information come from?

Every trial, status, phase and sponsor on this page is copied from public ClinicalTrials.gov records by a daily sync. Nothing here describes how ATRA works or whether it is effective, and it is not medical advice.

How this page is built

Everything on this page is copied from public ClinicalTrials.gov registry records โ€” it is not written from memory, and nothing here describes how ATRA works or whether it is effective. Each trial links to its own record so you can check it yourself.

This page is built automatically: a daily sync job reads the registry records behind our country trial registers, collects every trial that lists ATRA (or a registered synonym) as a drug or biological intervention, and tabulates the registry fields directly. Placebos and generic comparators are excluded. There is no AI drafting and no per-compound editorial pass, and the page has not been clinically reviewed. The “last verified” date above is the timestamp of that sync, not a review date. Our general editorial approach is described in our editorial standards and corrections policy. The ClinicalTrials.gov data on this page was last retrieved on 25 Sep 2026.

Please verify before you rely on this. This page is general information for life-science and pharmaceutical professionals. It is not medical advice, and it has not been reviewed by a clinician โ€” our editorial team holds life-science qualifications, not clinical ones. It is not exhaustive and may not reflect the most recent label change. Always check the official prescribing information (US Prescribing Information or EU SmPC) and speak to your doctor or pharmacist before acting on anything here. Drugs in the same class are not automatically interchangeable, and approvals, brand names and indications differ between the US, the EU/Ireland (EMA/HPRA) and other regions. Spotted an error? Tell us โ€” we correct promptly and log it.