Alpelisib is named as a drug or biological intervention in 12 clinical trials in our USA, UK, China, Ireland and India trial registers, 4 of which are recruiting. Lead sponsors include Novartis Pharmaceuticals (6), Hoffmann-La Roche (1) and Stemline Therapeutics, Inc. (1). Registered phases: Phase 2, Phase 3, Phase 1, Phase 1/2 and Phase 2/3. Conditions studied include Breast Cancer; PIK3CA-related Overgrowth Spectrum (PROS); Metastatic Breast Cancer.
Registers list studies that are recruiting, about to open, active but closed to enrolment, or enrolling by invitation. The UK and USA registers cover industry-sponsored studies only. Trial titles and statuses are copied from the registry as published.
| Condition (as registered) | Trials |
|---|---|
| Breast Cancer | 6 |
| PIK3CA-related Overgrowth Spectrum (PROS) | 3 |
| Metastatic Breast Cancer | 3 |
| Lymphatic Malformations | 1 |
| Advanced Breast Cancer | 1 |
| Endometrial Cancer | 1 |
| Advanced HER2+Breast Cancer | 1 |
| ER-positive Breast Cancer | 1 |
| HER2-negative Breast Cancer | 1 |
| Salivary Gland Carcinoma | 1 |
| Precision Therapy | 1 |
| Lead sponsor | Trials |
|---|---|
| Novartis Pharmaceuticals | 6 |
| Hoffmann-La Roche | 1 |
| Stemline Therapeutics, Inc. | 1 |
| Celcuity Inc | 1 |
| Eli Lilly and Company | 1 |
| Olema Pharmaceuticals, Inc. | 1 |
| Peking Union Medical College | 1 |
| Register | Alpelisib trials |
|---|---|
| Clinical trials in USA | 10 |
| Clinical trials in UK | 6 |
| Clinical trials in China | 6 |
| Clinical trials in Ireland | 2 |
| Clinical trials in India | 1 |
A trial with sites in more than one country appears in each of those registers.
Everything on this page is copied from public ClinicalTrials.gov registry records — it is not written from memory, and nothing here describes how Alpelisib works or whether it is effective. Each trial links to its own record so you can check it yourself.
This page is built automatically: a daily sync job reads the registry records behind our country trial registers, collects every trial that lists Alpelisib (or a registered synonym) as a drug or biological intervention, and tabulates the registry fields directly. Placebos and generic comparators are excluded. There is no AI drafting and no per-compound editorial pass, and the page has not been clinically reviewed. The “last verified” date above is the timestamp of that sync, not a review date. Our general editorial approach is described in our editorial standards and corrections policy. The ClinicalTrials.gov data on this page was last retrieved on 24 Sep 2026.