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Compound · clinical trials

Pembrolizumab/Vibostolimab clinical trials

Also listed in trial records as Pembrolizumab/Vibostolimab Co, MK-7684A, Coformulated vibostolimab/pembrolizumab
Source: ClinicalTrials.gov, U.S. National Library of Medicine — the 3 trials in our UK, USA, France, Spain, Italy, Netherlands, Canada, South Korea, Germany, Poland, Turkey, Australia, Israel, Ireland, China, Austria, Portugal, Mexico, Japan, Belgium, Denmark and Taiwan registers that name Pembrolizumab/Vibostolimab as an intervention. Synced 28 Sep 2026
3Current trials
0Recruiting now
1Lead sponsor
22Country registers
Maintained by Sreepriya Prasannan
MSc Digital Transformation of Life Sciences (Innopharma Education / Griffith College); MSc & BSc Botany HSE Spark Ignite 2026 โ€” Top 14 finalist
Compiled from ClinicalTrials.gov registry records ยท Last verified ยท Editorial standards
At a glance

Pembrolizumab/Vibostolimab is named as an intervention in 3 current clinical trials in our UK, USA, France, Spain, Italy, Netherlands, Canada, South Korea, Germany, Poland, Turkey, Australia, Israel, Ireland, China, Austria, Portugal, Mexico, Japan, Belgium, Denmark and Taiwan registers. None are recruiting at the moment. The most common phase is Phase 3. The lead sponsor is Merck Sharp & Dohme LLC. The most-studied condition is Small Cell Lung Carcinoma.

Trials by status

  • Active, closed3100%

Trials by phase

  • Phase 3133%
  • Phase 2133%
  • Phase 1/2133%
01

Clinical trials of Pembrolizumab/Vibostolimab

3 trials
StudyPhaseStatusLead sponsorRegisters
Pembrolizumab/Vibostolimab (MK-7684A) or Atezolizumab in Combination With Chemotherapy in First Line Treatment of Extensive-Stage Small Cell Lung Cancer (MK-7684A-008/KEYVIBE-008)
NCT05224141 · Small Cell Lung Carcinoma
Phase 3 Active, closed Merck Sharp & Dohme LLC Ireland, UK, USA, China, Germany, France, Spain, Italy, Netherlands, Poland, Austria, Portugal, Turkey, Canada, Mexico, Japan, South Korea, Australia, Israel
Evaluation of Co-formulated Pembrolizumab/Quavonlimab (MK-1308A) Versus Other Treatments in Participants With Microsatellite Instability-High (MSI-H) or Mismatch Repair Deficient (dMMR) Stage IV Colorectal Cancer (CRC) (MK-1308A-008/KEYSTEP-008).
NCT04895722 · ClinicalTrials.gov ↗ · Colorectal Cancer
Phase 2 Active, closed Merck Sharp & Dohme LLC UK, USA, Germany, France, Spain, Italy, Netherlands, Belgium, Denmark, Poland, Turkey, Canada, South Korea
A Study of Efficacy and Safety of Pembrolizumab Plus Enfortumab Vedotin (EV) +/- Investigational Agents in First-Line Metastatic Urothelial Carcinoma (mUC) (MK-3475-04B/KEYMAKER-U04)
NCT05845814 · ClinicalTrials.gov ↗ · Metastatic Urothelial Carcinoma, Urothelial Neoplasms
Phase 1/2 Active, closed Merck Sharp & Dohme LLC UK, USA, France, Spain, Italy, Netherlands, Canada, South Korea, Taiwan, Australia, Israel

Registers list studies that are recruiting, about to open, active but closed to enrolment, or enrolling by invitation. The UK and USA registers cover industry-sponsored studies only. Trial titles and statuses are copied from the registry as published.

02

Conditions studied with Pembrolizumab/Vibostolimab

4 conditions
Small Cell Lung Carcinoma1Colorectal Cancer1Metastatic Urothelial Carcinoma1Urothelial Neoplasms1
03

Sponsors

lead sponsor per trial
Lead sponsorTrials
Merck Sharp & Dohme LLC3
04

By country register

RegisterTrialsRecruiting
Clinical trials in UK30
Clinical trials in USA30
Clinical trials in France30
Clinical trials in Spain30
Clinical trials in Italy30
Clinical trials in Netherlands30
Clinical trials in Canada30
Clinical trials in South Korea30
Clinical trials in Germany20
Clinical trials in Poland20
Clinical trials in Turkey20
Clinical trials in Australia20
Clinical trials in Israel20
Clinical trials in Ireland10
Clinical trials in China10
Clinical trials in Austria10
Clinical trials in Portugal10
Clinical trials in Mexico10
Clinical trials in Japan10
Clinical trials in Belgium10
Clinical trials in Denmark10
Clinical trials in Taiwan10

A trial with sites in more than one country appears in each of those registers.

05

Related compounds

06

Questions about Pembrolizumab/Vibostolimab trials

How many clinical trials are testing Pembrolizumab/Vibostolimab?

3 current trials in our UK, USA, France, Spain, Italy, Netherlands, Canada, South Korea, Germany, Poland, Turkey, Australia, Israel, Ireland, China, Austria, Portugal, Mexico, Japan, Belgium, Denmark and Taiwan registers name Pembrolizumab/Vibostolimab (also registered as MK-7684A) as a drug or biological intervention, as of the registry sync on 28 September 2026. Completed and withdrawn studies are not counted.

Are Pembrolizumab/Vibostolimab trials recruiting patients?

Not at the moment. None of the 3 trials in our registers is recruiting; they are active but closed to enrolment, not yet open, or enrolling by invitation. Only the study team can confirm whether a patient is eligible.

Who sponsors Pembrolizumab/Vibostolimab clinical trials?

The lead sponsor is Merck Sharp & Dohme LLC. The number in brackets is how many trials each organisation leads.

Are there Pembrolizumab/Vibostolimab clinical trials in Ireland?

Yes. 1 trial in our Ireland register (ClinicalTrials.gov). Some may be the same study registered in both. See the Irish clinical trials register for sites and contacts.

Where does this information come from?

Every trial, status, phase and sponsor on this page is copied from public ClinicalTrials.gov records by a daily sync. Nothing here describes how Pembrolizumab/Vibostolimab works or whether it is effective, and it is not medical advice.

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How this page is built

Everything on this page is copied from public ClinicalTrials.gov registry records โ€” it is not written from memory, and nothing here describes how Pembrolizumab/Vibostolimab works or whether it is effective. Each trial links to its own record so you can check it yourself.

This page is built automatically: a daily sync job reads the registry records behind our country trial registers, collects every trial that lists Pembrolizumab/Vibostolimab (or a registered synonym) as a drug or biological intervention, and tabulates the registry fields directly. Placebos and generic comparators are excluded. There is no AI drafting and no per-compound editorial pass, and the page has not been clinically reviewed. The “last verified” date above is the timestamp of that sync, not a review date. Our general editorial approach is described in our editorial standards and corrections policy. The ClinicalTrials.gov data on this page was last retrieved on 28 Sep 2026.

Please verify before you rely on this. This page is general information for life-science and pharmaceutical professionals. It is not medical advice, and it has not been reviewed by a clinician โ€” our editorial team holds life-science qualifications, not clinical ones. It is not exhaustive and may not reflect the most recent label change. Always check the official prescribing information (US Prescribing Information or EU SmPC) and speak to your doctor or pharmacist before acting on anything here. Drugs in the same class are not automatically interchangeable, and approvals, brand names and indications differ between the US, the EU/Ireland (EMA/HPRA) and other regions. Spotted an error? Tell us โ€” we correct promptly and log it.