Ireland
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Priya Life Science Compound trial record
Compound · clinical trials

MK-4830 clinical trials

Source: ClinicalTrials.gov, U.S. National Library of Medicine — the 4 trials in our USA, Italy, South Korea, Spain, Poland, Canada, Germany, Turkey, Switzerland, Taiwan, Israel, UK, France, Netherlands, Belgium, Denmark, China, Norway, Brazil, Japan, Singapore, Austria and Australia registers that name MK-4830 as an intervention. Synced 9 Nov 2026
4Current trials
2Recruiting now
1Lead sponsor
23Country registers
At a glance

MK-4830 is named as an intervention in 4 current clinical trials in our USA, Italy, South Korea, Spain, Poland, Canada, Germany, Turkey, Switzerland, Taiwan, Israel, UK, France, Netherlands, Belgium, Denmark, China, Norway, Brazil, Japan, Singapore, Austria and Australia registers. 2 are recruiting patients now. The most common phase is Phase 1/2. The lead sponsor is Merck Sharp & Dohme LLC. The most-studied condition is Colorectal Cancer.

Patient leaflets for MK-4830

The package leaflet is the official guide for patients that comes with every medicine. These links go to the regulators that publish it.

  • UK
    United Kingdom: Search MHRA Products
    Patient information leaflets and SmPCs for UK-licensed products.
  • US
    United States: Search DailyMed
    FDA-approved labels, including patient and medication guides.

Leaflets differ between brands and countries; always read the one that comes with your own medicine. This is regulatory information, not medical advice.

Trials by status

  • Recruiting250%
  • Active, closed250%

Trials by phase

  • Phase 1/2375%
  • Phase 2125%
01

Clinical trials of MK-4830

4 trials
StudyPhaseStatusLead sponsorRegisters
KEYMAKER-U01 Substudy 01A: Efficacy and Safety Study of Pembrolizumab (MK-3475) With or Without Chemotherapy When Used With Investigational Agents in Treatment-naïve Participants With Stage IV Non-small Cell Lung Cancer (NSCLC) (MK-3475-01A/KEYMAKER-U01A)
NCT04165070 · Carcinoma, Non-Small-Cell Lung
Phase 1/2 Recruiting Merck Sharp & Dohme LLC USA, Spain, Italy, Poland, Canada, South Korea, Taiwan, Israel
A Study to Evaluate Investigational Agents With or Without Pembrolizumab (MK-3475) in Participants With Advanced Esophageal Cancer Previously Exposed to Programmed Cell Death 1 Protein (PD-1)/ Programmed Cell Death Ligand 1 (PD-L1) Treatment (MK-3475-06B)
NCT05319730 · Esophageal Squamous Cell Carcinoma
Phase 1/2 Recruiting Merck Sharp & Dohme LLC USA, China, Germany, Italy, Switzerland, Norway, Turkey, Brazil, Japan, South Korea, Taiwan, Singapore
Evaluation of Co-formulated Pembrolizumab/Quavonlimab (MK-1308A) Versus Other Treatments in Participants With Microsatellite Instability-High (MSI-H) or Mismatch Repair Deficient (dMMR) Stage IV Colorectal Cancer (CRC) (MK-1308A-008/KEYSTEP-008).
NCT04895722 · Colorectal Cancer
Phase 2 Active, closed Merck Sharp & Dohme LLC UK, USA, Germany, France, Spain, Italy, Netherlands, Belgium, Denmark, Poland, Turkey, Canada, South Korea
Safety and Efficacy Study of Investigational Agents as Monotherapy or in Combination With Pembrolizumab (MK-3475) for the Treatment of Extensive-Stage Small Cell Lung Cancer (ES-SCLC) in Need of Second-Line Therapy (MK-3475-B98/KEYNOTE-B98)
NCT04938817 · Small Cell Lung Carcinoma
Phase 1/2 Active, closed Merck Sharp & Dohme LLC USA, Spain, Italy, Poland, Switzerland, Austria, Canada, South Korea, Australia, Israel

Registers list studies that are recruiting, about to open, active but closed to enrolment, or enrolling by invitation. The UK and USA registers cover industry-sponsored studies only. Trial titles and statuses are copied from the registry as published.

02

Conditions studied with MK-4830

4 conditions
05

Related compounds

06

Questions about MK-4830 trials

How many clinical trials are testing MK-4830?

4 current trials in our USA, Italy, South Korea, Spain, Poland, Canada, Germany, Turkey, Switzerland, Taiwan, Israel, UK, France, Netherlands, Belgium, Denmark, China, Norway, Brazil, Japan, Singapore, Austria and Australia registers name MK-4830 as a drug or biological intervention, as of the registry sync on 9 November 2026. Completed and withdrawn studies are not counted.

Are MK-4830 trials recruiting patients?

Yes. 2 of the 4 trials are recruiting: 2 with sites in USA, 2 with sites in Italy, 2 with sites in South Korea, 1 with sites in Spain, 1 with sites in Poland, 1 with sites in Canada, 1 with sites in Germany, 1 with sites in Turkey, 1 with sites in Switzerland, 2 with sites in Taiwan, 1 with sites in Israel, 1 with sites in China, 1 with sites in Norway, 1 with sites in Brazil, 1 with sites in Japan and 1 with sites in Singapore. Eligibility and site contacts are on each trial's record. Only the study team can confirm whether a patient is eligible.

Who sponsors MK-4830 clinical trials?

The lead sponsor is Merck Sharp & Dohme LLC. The number in brackets is how many trials each organisation leads.

Where does this information come from?

Every trial, status, phase and sponsor on this page is copied from public ClinicalTrials.gov records by a daily sync. Nothing here describes how MK-4830 works or whether it is effective, and it is not medical advice.

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How this page is built

Everything on this page is copied from public ClinicalTrials.gov registry records — it is not written from memory, and nothing here describes how MK-4830 works or whether it is effective. Each trial links to its own record so you can check it yourself.

This page is built automatically: a daily sync job reads the registry records behind our country trial registers, collects every trial that lists MK-4830 (or a registered synonym) as a drug or biological intervention, and tabulates the registry fields directly. Placebos and generic comparators are excluded. There is no AI drafting and no per-compound editorial pass, and the page has not been clinically reviewed. The “last verified” date above is the timestamp of that sync, not a review date. Our general editorial approach is described in our editorial standards and corrections policy. The ClinicalTrials.gov data on this page was last retrieved on 9 Nov 2026. How every register is built: methodology · fixes we have made: corrections log.

Please verify before you rely on this. This page is general information for life-science and pharmaceutical professionals. It is not medical advice, and it has not been reviewed by a clinician — our editorial team holds life-science qualifications, not clinical ones. It is not exhaustive and may not reflect the most recent label change. Always check the official prescribing information (US Prescribing Information or EU SmPC) and speak to your doctor or pharmacist before acting on anything here. Drugs in the same class are not automatically interchangeable, and approvals, brand names and indications differ between the US, the EU/Ireland (EMA/HPRA) and other regions. Spotted an error? Tell us — we correct promptly and log it.