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Priya Life Science Compound trial record
Compound · clinical trials

Navlimetostat clinical trials

Also listed in trial records as BMS-986504, MRTX1719, [14C]Navlimetostat, MRTX-1719
Source: ClinicalTrials.gov, U.S. National Library of Medicine — the 10 trials in our USA, China, Spain, Japan, Germany, France, Italy, UK, Netherlands, Belgium, Sweden, Poland, Canada, South Korea, Australia, Ireland, India, Denmark, Austria, Czechia, Turkey, Brazil, Mexico, Taiwan, Israel, Norway, Switzerland and Singapore registers that name Navlimetostat as an intervention. Synced 10 Nov 2026
10Current trials
9Recruiting now
1Lead sponsor
28Country registers
At a glance

Navlimetostat is named as an intervention in 10 current clinical trials in our USA, China, Spain, Japan, Germany, France, Italy, UK, Netherlands, Belgium, Sweden, Poland, Canada, South Korea, Australia, Ireland, India, Denmark, Austria, Czechia, Turkey, Brazil, Mexico, Taiwan, Israel, Norway, Switzerland and Singapore registers. 9 are recruiting patients now. The most common phase is Phase 1. The lead sponsor is Bristol-Myers Squibb. The most-studied condition is Pancreatic Ductal Adenocarcinoma.

Patient leaflets for Navlimetostat

The package leaflet is the official guide for patients that comes with every medicine. These links go to the regulators that publish it.

  • UK
    United Kingdom: Search MHRA Products
    Patient information leaflets and SmPCs for UK-licensed products.
  • US
    United States: Search DailyMed
    FDA-approved labels, including patient and medication guides.

Leaflets differ between brands and countries; always read the one that comes with your own medicine. This is regulatory information, not medical advice.

Trials by status

  • Recruiting990%
  • Active, closed110%

Trials by phase

  • Phase 1660%
  • Phase 2/3220%
  • Phase 2220%
01

Clinical trials of Navlimetostat

10 trials
StudyPhaseStatusLead sponsorRegisters
A Study to Compare the Combination of Navlimetostat (BMS-986504) With Pembrolizumab and Chemotherapy Versus Placebo Plus Pembrolizumab and Chemotherapy in First-line Metastatic Non-small Cell Lung Cancer Participants With Homozygous MTAP Deletion
NCT07063745 · Metastatic Non-small Cell Lung Cancer With MTAP Deletion
Phase 2/3 Recruiting Bristol-Myers Squibb UK, USA, India, China, Germany, France, Spain, Italy, Netherlands, Belgium, Sweden, Denmark, Poland, Austria, Czechia, Norway, Turkey, Brazil, Mexico, Japan, South Korea, Taiwan, Australia, Israel
A Study of Navlimetostat (BMS-986504) Alone or in Combination With Izalontamab Brengitecan in Participants With Pre-treated Advanced or Metastatic Non-small Cell Lung Cancer (NSCLC) With Homozygous MTAP Deletion or MTAP Loss (MountainTAP-9)
NCT06855771 · Carcinoma, Non-Small-Cell Lung
Phase 2 Recruiting Bristol-Myers Squibb UK, USA, China, Germany, France, Spain, Italy, Sweden, Poland, Japan, Australia
A Study of Navlimetostat (BMS-986504) Monotherapy and in Combination With Other Agents in Participants With Advanced and/or Metastatic Solid Tumors With Homozygous MTAP Deletion (MountainTAP-5)
NCT07492680 · Solid Tumors
Phase 2 Recruiting Bristol-Myers Squibb Ireland, USA, China, Germany, France, Spain, Italy, Belgium, Norway, Canada, Japan, South Korea
Phase 1 Study of MRTX1719 in Solid Tumors With MTAP Deletion
NCT05245500 · Mesothelioma, Non Small Cell Lung Cancer, Malignant Peripheral Nerve Sheath Tumors
Phase 1 Recruiting Bristol-Myers Squibb USA
A Study to Evaluate the Mass Balance, Metabolism, Elimination, and Drug Levels of [14C]-BMS-986504 (MRTX1719) in Participants With Advanced Solid Tumors With Homozygous Methylthioadenosine Phosphorylase Deletion
NCT06672523 · ClinicalTrials.gov ↗ · Advanced Solid Tumors With Homozygous MTAP Deletion
Phase 1 Recruiting Bristol-Myers Squibb Spain
A Study to Assess Safety, Tolerability and Drug Levels of Navlimetostat (BMS-986504) in Participants With Advanced Solid Tumors
NCT07077434 · ClinicalTrials.gov ↗ · Advanced Solid Tumors
Phase 1 Recruiting Bristol-Myers Squibb China, Japan
A Phase 1 Study of Navlimetostat Tablet Formulations
NCT07544628 · ClinicalTrials.gov ↗ · Healthy Participants
Phase 1 Recruiting Bristol-Myers Squibb USA
A Study to Evaluate the Metabolism, the Routes and Extent of Elimination, and Drug Levels of [14C]Navlimetostat (BMS-986504) in Healthy Female Participants
NCT07777133 · Healthy Female Participants
Phase 1 Recruiting Bristol-Myers Squibb USA, Netherlands
A Study of Navlimetostat (BMS-986504) Drug Interactions and Food Effect in Healthy Participants
NCT07800897 · ClinicalTrials.gov ↗ · Healthy Female Adults
Phase 1 Recruiting Bristol-Myers Squibb Canada
A Study Comparing Navlimetostat (BMS-986504) in Combination With Nab-paclitaxel and Gemcitabine Versus Placebo in Combination With Nab-paclitaxel and Gemcitabine in Participants With Untreated Metastatic Pancreatic Ductal Adenocarcinoma With Homozygous MTAP Deletion (MountainTAP-30)
NCT07076121 · Pancreatic Ductal Adenocarcinoma
Phase 2/3 Active, closed Bristol-Myers Squibb Ireland, UK, USA, India, China, Germany, France, Spain, Italy, Netherlands, Belgium, Sweden, Denmark, Poland, Switzerland, Austria, Czechia, Turkey, Canada, Brazil, Mexico, Japan, South Korea, Taiwan, Singapore, Australia, Israel

Registers list studies that are recruiting, about to open, active but closed to enrolment, or enrolling by invitation. The UK and USA registers cover industry-sponsored studies only. Trial titles and statuses are copied from the registry as published.

02

Conditions studied with Navlimetostat

13 conditions
Pancreatic Ductal Adenocarcinoma1Solid Tumors1Carcinoma, Non-Small-Cell Lung1Healthy Female Participants1Healthy Participants1Healthy Female Adults1Metastatic Non-small Cell Lung Cancer With MTAP Deletion1Advanced Solid Tumors1Advanced Solid Tumors With Homozygous MTAP Deletion1Mesothelioma1Non Small Cell Lung Cancer1Malignant Peripheral Nerve Sheath Tumors1
All 13 conditions
Condition (as registered)Trials
Pancreatic Ductal Adenocarcinoma1
Solid Tumors1
Carcinoma, Non-Small-Cell Lung1
Healthy Female Participants1
Healthy Participants1
Healthy Female Adults1
Metastatic Non-small Cell Lung Cancer With MTAP Deletion1
Advanced Solid Tumors1
Advanced Solid Tumors With Homozygous MTAP Deletion1
Mesothelioma1
Non Small Cell Lung Cancer1
Malignant Peripheral Nerve Sheath Tumors1
Solid Tumor1
05

Related compounds

06

Questions about Navlimetostat trials

How many clinical trials are testing Navlimetostat?

10 current trials in our USA, China, Spain, Japan, Germany, France, Italy, UK, Netherlands, Belgium, Sweden, Poland, Canada, South Korea, Australia, Ireland, India, Denmark, Austria, Czechia, Turkey, Brazil, Mexico, Taiwan, Israel, Norway, Switzerland and Singapore registers name Navlimetostat (also registered as BMS-986504) as a drug or biological intervention, as of the registry sync on 10 November 2026. Completed and withdrawn studies are not counted.

Are Navlimetostat trials recruiting patients?

Yes. 9 of the 10 trials are recruiting: 6 with sites in USA, 4 with sites in China, 4 with sites in Spain, 4 with sites in Japan, 3 with sites in Germany, 3 with sites in France, 3 with sites in Italy, 2 with sites in UK, 2 with sites in Netherlands, 2 with sites in Belgium, 2 with sites in Sweden, 2 with sites in Poland, 2 with sites in Canada, 2 with sites in South Korea, 2 with sites in Australia, 1 with sites in Ireland, 1 with sites in India, 1 with sites in Denmark, 1 with sites in Austria, 1 with sites in Czechia, 1 with sites in Turkey, 1 with sites in Brazil, 1 with sites in Mexico, 1 with sites in Taiwan, 1 with sites in Israel and 2 with sites in Norway. Eligibility and site contacts are on each trial's record. Only the study team can confirm whether a patient is eligible.

Who sponsors Navlimetostat clinical trials?

The lead sponsor is Bristol-Myers Squibb. The number in brackets is how many trials each organisation leads.

Are there Navlimetostat clinical trials in Ireland?

Yes. 2 trials in our Ireland register (ClinicalTrials.gov). Some may be the same study registered in both. See the Irish clinical trials register for sites and contacts.

Where does this information come from?

Every trial, status, phase and sponsor on this page is copied from public ClinicalTrials.gov records by a daily sync. Nothing here describes how Navlimetostat works or whether it is effective, and it is not medical advice.

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How this page is built

Everything on this page is copied from public ClinicalTrials.gov registry records — it is not written from memory, and nothing here describes how Navlimetostat works or whether it is effective. Each trial links to its own record so you can check it yourself.

This page is built automatically: a daily sync job reads the registry records behind our country trial registers, collects every trial that lists Navlimetostat (or a registered synonym) as a drug or biological intervention, and tabulates the registry fields directly. Placebos and generic comparators are excluded. There is no AI drafting and no per-compound editorial pass, and the page has not been clinically reviewed. The “last verified” date above is the timestamp of that sync, not a review date. Our general editorial approach is described in our editorial standards and corrections policy. The ClinicalTrials.gov data on this page was last retrieved on 10 Nov 2026. How every register is built: methodology · fixes we have made: corrections log.

Please verify before you rely on this. This page is general information for life-science and pharmaceutical professionals. It is not medical advice, and it has not been reviewed by a clinician — our editorial team holds life-science qualifications, not clinical ones. It is not exhaustive and may not reflect the most recent label change. Always check the official prescribing information (US Prescribing Information or EU SmPC) and speak to your doctor or pharmacist before acting on anything here. Drugs in the same class are not automatically interchangeable, and approvals, brand names and indications differ between the US, the EU/Ireland (EMA/HPRA) and other regions. Spotted an error? Tell us — we correct promptly and log it.