Ireland
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Priya Life Science Compound trial record
Compound · clinical trials

Elironrasib clinical trials

Also listed in trial records as RMC-6291
Source: ClinicalTrials.gov, U.S. National Library of Medicine — the 4 trials in our USA, France, Spain, Italy, Germany, Netherlands, Czechia, South Korea, Taiwan, Australia, Denmark, Austria, Poland and Singapore registers that name Elironrasib as an intervention. Synced 9 Nov 2026
4Current trials
3Recruiting now
1Lead sponsor
14Country registers
At a glance

Elironrasib is named as an intervention in 4 current clinical trials in our USA, France, Spain, Italy, Germany, Netherlands, Czechia, South Korea, Taiwan, Australia, Denmark, Austria, Poland and Singapore registers. 3 are recruiting patients now. The most common phase is Phase 1/2. The lead sponsor is Revolution Medicines, Inc. The most-studied condition is Non-Small Cell Lung Cancer (NSCLC). The EU clinical trials register (CTIS) separately lists 1 authorised or ongoing trial, 1 with a site in Ireland.

Patient leaflets for Elironrasib

The package leaflet is the official guide for patients that comes with every medicine. These links go to the regulators that publish it.

  • UK
    United Kingdom: Search MHRA Products
    Patient information leaflets and SmPCs for UK-licensed products.
  • US
    United States: Search DailyMed
    FDA-approved labels, including patient and medication guides.

Leaflets differ between brands and countries; always read the one that comes with your own medicine. This is regulatory information, not medical advice.

Trials by status

  • Recruiting375%
  • Active, closed125%

Trials by phase

  • Phase 1/2375%
  • Phase 1125%
01

Clinical trials of Elironrasib

4 trials
StudyPhaseStatusLead sponsorRegisters
Study of Elironrasib and Daraxonrasib as Monotherapies and Combination Therapy in Participants With Advanced KRAS G12C Mutant Solid Tumors
NCT06128551 · Non-Small Cell Lung Cancer (NSCLC), Colorectal Cancer, Pancreatic Ductal Adenocarcinoma
Phase 1/2 Recruiting Revolution Medicines, Inc USA, Germany, France, Spain, Italy, Netherlands
Study of RAS(ON) Inhibitors in Patients With Advanced RAS-mutated NSCLC
NCT06162221 · Non-Small Cell Lung Cancer, NSCLC, KRAS, NRAS, HRAS-mutated NSCLC, KRAS G12C-mutated Solid Tumors, Lung Cancer
Phase 1/2 Recruiting Revolution Medicines, Inc USA, Germany, France, Spain, Italy, Netherlands, Denmark, Austria, Czechia, South Korea, Taiwan, Australia
Study of RAS(ON) Inhibitors in Combination With Ivonescimab in Patients With Solid Tumors
NCT07397338 · Advanced Solid Tumors, Metastatic Solid Tumors, Non-small Cell Lung Cancer (NSCLC)
Phase 1/2 Recruiting Revolution Medicines, Inc USA
Dose Escalation and Dose Expansion Study of RMC-6291 Monotherapy in Subjects With Advanced KRASG12C Mutant Solid Tumors
NCT05462717 · Non-Small Cell Lung Cancer (NSCLC), Colorectal Cancer (CRC), Pancreatic Ductal Adenocarcinoma
Phase 1 Active, closed Revolution Medicines, Inc USA, France, Spain, Italy, Poland, Czechia, South Korea, Taiwan, Singapore, Australia

Registers list studies that are recruiting, about to open, active but closed to enrolment, or enrolling by invitation. The UK and USA registers cover industry-sponsored studies only. Trial titles and statuses are copied from the registry as published.

02

Elironrasib in the EU trials register (CTIS)

1 trial · 1 in Ireland

Authorised or ongoing trials in the EU Clinical Trials Information System that list a product containing Elironrasib. Many trials are registered in both CTIS and ClinicalTrials.gov, so these are shown separately rather than added to the count above. Trials with a site in Ireland are listed first.

StudyPhaseStatusSponsorCountries
A Phase 1/2 Open-Label, Multicenter Study of RAS(ON) inhibitors in Combination with Ivonescimab with or without Other Anti-Cancer Agents in Patients with Solid Tumors
2025-524623-50-00 · Neoplasms
Phase 1 Ongoing Revolution Medicines Inc Ireland + 8 more
03

Conditions studied with Elironrasib

13 conditions
All 13 conditions
Condition (as registered)Trials
Non-Small Cell Lung Cancer (NSCLC)2
Pancreatic Ductal Adenocarcinoma2
Advanced Solid Tumors1
Metastatic Solid Tumors1
Non-small Cell Lung Cancer (NSCLC)1
NSCLC1
Colorectal Cancer1
Non-Small Cell Lung Cancer, NSCLC1
KRAS, NRAS, HRAS-mutated NSCLC1
KRAS G12C-mutated Solid Tumors, Lung Cancer1
Lung Cancer Stage IV, Advanced Solid Tumor, Cancer1
Colorectal Cancer (CRC)1
Advanced Solid Tumor1
04

Sponsors

lead sponsor per trial
Lead sponsorTrials
Revolution Medicines, Inc4
05

By country register

RegisterTrialsRecruiting
Clinical trials in USA43
Clinical trials in France32
Clinical trials in Spain32
Clinical trials in Italy32
Clinical trials in Germany22
Clinical trials in Netherlands22
Clinical trials in Czechia21
Clinical trials in South Korea21
Clinical trials in Taiwan21
Clinical trials in Australia21
Clinical trials in Denmark11
Clinical trials in Austria11
Clinical trials in Poland10
Clinical trials in Singapore10
EU register (CTIS)1—

A trial with sites in more than one country appears in each of those registers. CTIS does not publish a recruiting flag; its trials may also appear in the registers above.

06

Related compounds

07

Questions about Elironrasib trials

How many clinical trials are testing Elironrasib?

4 current trials in our USA, France, Spain, Italy, Germany, Netherlands, Czechia, South Korea, Taiwan, Australia, Denmark, Austria, Poland and Singapore registers name Elironrasib (also registered as RMC-6291) as a drug or biological intervention, as of the registry sync on 9 November 2026. Completed and withdrawn studies are not counted.

Are Elironrasib trials recruiting patients?

Yes. 3 of the 4 trials are recruiting: 3 with sites in USA, 2 with sites in France, 2 with sites in Spain, 2 with sites in Italy, 2 with sites in Germany, 2 with sites in Netherlands, 1 with sites in Czechia, 1 with sites in South Korea, 1 with sites in Taiwan, 1 with sites in Australia, 1 with sites in Denmark and 1 with sites in Austria. Eligibility and site contacts are on each trial's record. Only the study team can confirm whether a patient is eligible.

Who sponsors Elironrasib clinical trials?

The lead sponsor is Revolution Medicines, Inc. The number in brackets is how many trials each organisation leads.

Are there Elironrasib clinical trials in Ireland?

Yes. 1 trial in the EU register (CTIS) list a site in Ireland. Some may be the same study registered in both. See the Irish clinical trials register for sites and contacts.

Where does this information come from?

Every trial, status, phase and sponsor on this page is copied from public ClinicalTrials.gov records by a daily sync. Nothing here describes how Elironrasib works or whether it is effective, and it is not medical advice.

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How this page is built

Everything on this page is copied from public ClinicalTrials.gov registry records — it is not written from memory, and nothing here describes how Elironrasib works or whether it is effective. Each trial links to its own record so you can check it yourself.

This page is built automatically: a daily sync job reads the registry records behind our country trial registers, collects every trial that lists Elironrasib (or a registered synonym) as a drug or biological intervention, and tabulates the registry fields directly. Placebos and generic comparators are excluded. There is no AI drafting and no per-compound editorial pass, and the page has not been clinically reviewed. The “last verified” date above is the timestamp of that sync, not a review date. Our general editorial approach is described in our editorial standards and corrections policy. The ClinicalTrials.gov data on this page was last retrieved on 9 Nov 2026. How every register is built: methodology · fixes we have made: corrections log.

Please verify before you rely on this. This page is general information for life-science and pharmaceutical professionals. It is not medical advice, and it has not been reviewed by a clinician — our editorial team holds life-science qualifications, not clinical ones. It is not exhaustive and may not reflect the most recent label change. Always check the official prescribing information (US Prescribing Information or EU SmPC) and speak to your doctor or pharmacist before acting on anything here. Drugs in the same class are not automatically interchangeable, and approvals, brand names and indications differ between the US, the EU/Ireland (EMA/HPRA) and other regions. Spotted an error? Tell us — we correct promptly and log it.