M9140 is named as a drug or biological intervention in 3 clinical trials in our USA and China trial registers, none of which are currently recruiting. Lead sponsors include EMD Serono Research & Development Institute, Inc. (2) and Merck Healthcare KGaA, Darmstadt, Germany, an affiliate of Merck KGaA, Darmstadt, Germany (1). Registered phases: Phase 1 and Phase 1/2. Conditions studied include Solid Tumors; Colorectal Cancer; Gastric Cancer.
| NCT ID | Study | Phase | Status |
|---|---|---|---|
| NCT06710132 | Study of Anti-CEACAM5 ADC M9140 in Participants With Advanced Solid Tumors (PROCEADE PanTumor) Solid Tumors, Gastric Cancer, Non-Small Cell Lung Cancer (NSCLC) |
Phase 1/2 | Active, closed |
| NCT05464030 | Anti-CEACAM5 ADC M9140 in Advanced Solid Tumors (PROCEADE-CRC-01) (ClinicalTrials.gov ↗) Colorectal Cancer |
Phase 1 | Active, closed |
| NCT06806046 | Anti-CEACAM5 ADC Precemtabart Tocentecan (M9140) in Chinese Participants With Solid Tumors (ClinicalTrials.gov ↗) Solid Tumors, Colorectal Cancer |
Phase 1 | Active, closed |
Registers list studies that are recruiting, about to open, active but closed to enrolment, or enrolling by invitation. The UK and USA registers cover industry-sponsored studies only. Trial titles and statuses are copied from the registry as published.
| Condition (as registered) | Trials |
|---|---|
| Solid Tumors | 2 |
| Colorectal Cancer | 2 |
| Gastric Cancer | 1 |
| Non-Small Cell Lung Cancer (NSCLC) | 1 |
| Pancreatic Cancer | 1 |
| Lead sponsor | Trials |
|---|---|
| EMD Serono Research & Development Institute, Inc. | 2 |
| Merck Healthcare KGaA, Darmstadt, Germany, an affiliate of Merck KGaA, Darmstadt, Germany | 1 |
| Register | M9140 trials |
|---|---|
| Clinical trials in USA | 2 |
| Clinical trials in China | 2 |
A trial with sites in more than one country appears in each of those registers.
Everything on this page is copied from public ClinicalTrials.gov registry records — it is not written from memory, and nothing here describes how M9140 works or whether it is effective. Each trial links to its own record so you can check it yourself.
This page is built automatically: a daily sync job reads the registry records behind our country trial registers, collects every trial that lists M9140 (or a registered synonym) as a drug or biological intervention, and tabulates the registry fields directly. Placebos and generic comparators are excluded. There is no AI drafting and no per-compound editorial pass, and the page has not been clinically reviewed. The “last verified” date above is the timestamp of that sync, not a review date. Our general editorial approach is described in our editorial standards and corrections policy. The ClinicalTrials.gov data on this page was last retrieved on 24 Sep 2026.