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Compound · clinical trials

Folinic acid

Source: ClinicalTrials.gov, U.S. National Library of Medicine — the 6 trials in our USA, China and UK registers that name Folinic acid as an intervention. Synced 24 Sep 2026
6Trials tracked
2Recruiting now
4Lead sponsors
3Country registers
Maintained by Sreepriya Prasannan
MSc Digital Transformation of Life Sciences (Innopharma Education / Griffith College); MSc & BSc Botany HSE Spark Ignite 2026 โ€” Top 14 finalist
Compiled from ClinicalTrials.gov registry records ยท Last verified ยท Editorial standards

Folinic acid is named as a drug or biological intervention in 6 clinical trials in our USA, China and UK trial registers, 2 of which are recruiting. Lead sponsors include Astellas Pharma Global Development, Inc. (3), AbbVie (1) and EMD Serono Research & Development Institute, Inc. (1). Registered phases: Phase 2, Phase 3 and Phase 1. Conditions studied include Locally Advanced Unresectable Gastroesophageal Junction (GEJ) Adenocarcinoma or Cancer; Locally Advanced Unresectable Gastric Adenocarcinoma or Cancer; Metastatic Gastric Adenocarcinoma or Cancer.

01

Clinical trials of Folinic acid

6 trials
NCT IDStudyPhaseStatusLead sponsorRegister
NCT07673887 A Study of ASP2138 Together With Chemotherapy and Pembrolizumab in Adults With Gastric Cancer (ClinicalTrials.gov ↗)
Gastric Adenocarcinoma, Gastroesophageal Junction (GEJ) Adenocarcinoma
Phase 3 Recruiting Astellas Pharma Global Development, Inc. USA
NCT05628038 The Combination of Hypofractionated Radiotherapy and Immunotherapy in Locally Recurrent Rectal Cancer (ClinicalTrials.gov ↗)
Recurrent Rectal Cancer
Phase 2 Recruiting Fudan University China
NCT03504397 A Study to Compare Zolbetuximab (IMAB362) and Chemotherapy With Placebo and Chemotherapy in Adults With Gastric Cancer. (ClinicalTrials.gov ↗)
Locally Advanced Unresectable Gastroesophageal Junction (GEJ) Adenocarcinoma or Cancer, Locally Advanced Unresectable Gastric Adenocarcinoma or Cancer, Metastatic Gastric Adenocarcinoma or Cancer
Phase 3 Active, closed Astellas Pharma Global Development, Inc. UK, USA, China
NCT03505320 A Study of Zolbetuximab (IMAB362) in Adults With Gastric Cancer
Pharmacokinetics of Zolbetuximab, Gastric Cancer, Gastro-esophageal Junction (GEJ) Cancer
Phase 2 Active, closed Astellas Pharma Global Development, Inc. USA
NCT06107413 Study to Assess Adverse Events and Change in Disease Activity in Previously Treated Adult Participants Receiving Intravenous (IV) ABBV-400 With Unresectable Metastatic Colorectal Cancer in Combination With IV Fluorouracil, Folinic Acid, and Bevacizumab (ClinicalTrials.gov ↗)
Unresectable Metastatic Colorectal Cancer
Phase 2 Active, closed AbbVie USA
NCT05464030 Anti-CEACAM5 ADC M9140 in Advanced Solid Tumors (PROCEADE-CRC-01) (ClinicalTrials.gov ↗)
Colorectal Cancer
Phase 1 Active, closed EMD Serono Research & Development Institute, Inc. USA

Registers list studies that are recruiting, about to open, active but closed to enrolment, or enrolling by invitation. The UK and USA registers cover industry-sponsored studies only. Trial titles and statuses are copied from the registry as published.

02

Conditions studied

13 conditions
Condition (as registered)Trials
Locally Advanced Unresectable Gastroesophageal Junction (GEJ) Adenocarcinoma or Cancer1
Locally Advanced Unresectable Gastric Adenocarcinoma or Cancer1
Metastatic Gastric Adenocarcinoma or Cancer1
Metastatic Gastroesophageal Junction (GEJ) Adenocarcinoma1
Pharmacokinetics of Zolbetuximab1
Gastric Cancer1
Gastro-esophageal Junction (GEJ) Cancer1
Pharmacokinetics of Oxaliplatin1
Unresectable Metastatic Colorectal Cancer1
Colorectal Cancer1
Gastric Adenocarcinoma1
Gastroesophageal Junction (GEJ) Adenocarcinoma1
Recurrent Rectal Cancer1
03

Sponsors

lead sponsor per trial
Lead sponsorTrials
Astellas Pharma Global Development, Inc.3
AbbVie1
EMD Serono Research & Development Institute, Inc.1
Fudan University1
04

Trials by country register

A trial with sites in more than one country appears in each of those registers.

How this page is built

Everything on this page is copied from public ClinicalTrials.gov registry records โ€” it is not written from memory, and nothing here describes how Folinic acid works or whether it is effective. Each trial links to its own record so you can check it yourself.

This page is built automatically: a daily sync job reads the registry records behind our country trial registers, collects every trial that lists Folinic acid (or a registered synonym) as a drug or biological intervention, and tabulates the registry fields directly. Placebos and generic comparators are excluded. There is no AI drafting and no per-compound editorial pass, and the page has not been clinically reviewed. The “last verified” date above is the timestamp of that sync, not a review date. Our general editorial approach is described in our editorial standards and corrections policy. The ClinicalTrials.gov data on this page was last retrieved on 24 Sep 2026.

Please verify before you rely on this. This page is general information for life-science and pharmaceutical professionals. It is not medical advice, and it has not been reviewed by a clinician โ€” our editorial team holds life-science qualifications, not clinical ones. It is not exhaustive and may not reflect the most recent label change. Always check the official prescribing information (US Prescribing Information or EU SmPC) and speak to your doctor or pharmacist before acting on anything here. Drugs in the same class are not automatically interchangeable, and approvals, brand names and indications differ between the US, the EU/Ireland (EMA/HPRA) and other regions. Spotted an error? Tell us โ€” we correct promptly and log it.