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Compound · clinical trials

Mavacamten clinical trials

Source: ClinicalTrials.gov, U.S. National Library of Medicine — the 12 trials in our USA, UK, China, Ireland and India registers that name Mavacamten as an intervention. Synced 25 Sep 2026
12Current trials
5Recruiting now
3Lead sponsors
5Country registers
Maintained by Sreepriya Prasannan
MSc Digital Transformation of Life Sciences (Innopharma Education / Griffith College); MSc & BSc Botany HSE Spark Ignite 2026 โ€” Top 14 finalist
Compiled from ClinicalTrials.gov registry records ยท Last verified ยท Editorial standards
At a glance

Mavacamten is named as an intervention in 12 current clinical trials in our USA, UK, China, Ireland and India registers. 5 are recruiting patients now. The most common phase is Observational. The sponsor with the most trials is Bristol-Myers Squibb (10). The most-studied condition is Cardiomyopathy, Hypertrophic.

Trials by status

  • Recruiting542%
  • Active, closed650%
  • By invitation18%

Trials by phase

  • Observational758%
  • Phase 4325%
  • Phase 318%
  • Not applicable18%
01

Clinical trials of Mavacamten

12 trials
StudyPhaseStatusLead sponsorRegisters
A Prospective Registry Study to Assess Real-world Patient Characteristics, Treatment Patterns, and Longitudinal Outcomes in Patients Receiving Mavacamten and Other Treatments for Symptomatic Obstructive Hypertrophic Cardiomyopathy (Obstructive-HCM)
NCT05489705 · ClinicalTrials.gov ↗ · Obstructive Hypertrophic Cardiomyopathy
Observational Recruiting Bristol-Myers Squibb UK, USA
Mavacamten Pregnancy Surveillance Program
NCT05939700 · Breastfeeding, Hypertrophic Cardiomyopathy, Pregnancy Related
Observational Recruiting Bristol-Myers Squibb USA
Real-world Patient Reported Outcomes Among Patients Treated With Camzyos
NCT06551129 · ClinicalTrials.gov ↗ · Obstructive Hypertrophic Cardiomyopathy
Observational Recruiting Bristol-Myers Squibb USA
A Study to Assess the Real-World Effectiveness of Mavacamten in Adult Patients With Obstructive Hypertrophic Cardiomyopathy in China
NCT07361289 · ClinicalTrials.gov ↗ · Hypertrophic Cardiomyopathy
Observational Recruiting Bristol-Myers Squibb China
Mavacamten Outcomes in Hypertrophic Cardiomyopathy (HCM) and the Associated Patient and Physician Experiences in the US
NCT07557498 · ClinicalTrials.gov ↗ · Obstructive Hypertrophic Cardiomyopathy (oHCM)
Observational Recruiting Bristol-Myers Squibb UK
The Therapeutic Value of Mavacamten in Hypertrophic Cardiomyopathy With Mid-to-Apical Left Ventricular Obstruction
NCT07103655 · ClinicalTrials.gov ↗ · Hypertrophic Cardiomyopathy (HCM)
Phase 4 By invitation Second Affiliated Hospital, Zhejiang University, School of Medicine China
A Study to Evaluate Mavacamten Impact on Myocardial Structure in Participants With Symptomatic Obstructive Hypertrophic Cardiomyopathy
NCT06112743 · ClinicalTrials.gov ↗ · Cardiomyopathy, Hypertrophic
Phase 4 Active, closed Bristol-Myers Squibb UK, USA
A Study of Mavacamten in Adults With Obstructive Hypertrophic Cardiomyopathy in India (ROVER)
NCT07004972 · ClinicalTrials.gov ↗ · Symptomatic Obstructive Hypertrophic Cardiomyopathy
Phase 4 Active, closed Bristol-Myers Squibb India
A Study to Evaluate Mavacamten in Adolescents With Symptomatic Obstructive Hypertrophic Cardiomyopathy
NCT06253221 · Cardiomyopathy, Hypertrophic
Phase 3 Active, closed Bristol-Myers Squibb Ireland, UK, USA
COLLIGO-HCM: A Multinational Observational Study of the Real-World Effectiveness of Mavacamten Among Patients With Symptomatic Obstructive Hypertrophic Cardiomyopathy (oHCM)
NCT06372457 · ClinicalTrials.gov ↗ · Hypertrophic Cardiomyopathy (HCM)
Observational Active, closed Bristol-Myers Squibb USA
A Study to Assess the Treatment of Obstructive Hypertrophic Cardiomyopathy (oHCM) With Mavacamten in the US
NCT07107373 · ClinicalTrials.gov ↗ · Obstructive Hypertrophic Cardiomyopathy (oHCM)
Observational Active, closed Bristol-Myers Squibb USA
Efficacy of Mavacamten in Patients With Symptomatic Latent Obstructive Hypertrophic Cardiomyopathy
NCT06947590 · ClinicalTrials.gov ↗ · HCM - Hypertrophic Cardiomyopathy, Mavacamten
Not applicable Active, closed Xu Liu China

Registers list studies that are recruiting, about to open, active but closed to enrolment, or enrolling by invitation. The UK and USA registers cover industry-sponsored studies only. Trial titles and statuses are copied from the registry as published.

02

Conditions studied with Mavacamten

10 conditions
Cardiomyopathy, Hypertrophic2Obstructive Hypertrophic Cardiomyopathy2Obstructive Hypertrophic Cardiomyopathy (oHCM)2Hypertrophic Cardiomyopathy2Hypertrophic Cardiomyopathy (HCM)2Breastfeeding1Pregnancy Related1Symptomatic Obstructive Hypertrophic Cardiomyopathy1HCM - Hypertrophic Cardiomyopathy1Mavacamten1
03

Sponsors

lead sponsor per trial
Lead sponsorTrials
Bristol-Myers Squibb10
Second Affiliated Hospital, Zhejiang University, School of Medicine1
Xu Liu1
04

By country register

RegisterTrialsRecruiting
Clinical trials in USA73
Clinical trials in UK42
Clinical trials in China31
Clinical trials in Ireland10
Clinical trials in India10

A trial with sites in more than one country appears in each of those registers.

05

Related compounds

06

Questions about Mavacamten trials

How many clinical trials are testing Mavacamten?

12 current trials in our USA, UK, China, Ireland and India registers name Mavacamten as a drug or biological intervention, as of the registry sync on 25 September 2026. Completed and withdrawn studies are not counted.

Are Mavacamten trials recruiting patients?

Yes. 5 of the 12 trials are recruiting: 3 with sites in USA, 2 with sites in UK and 1 with sites in China. Eligibility and site contacts are on each trial's record. Only the study team can confirm whether a patient is eligible.

Who sponsors Mavacamten clinical trials?

Bristol-Myers Squibb (10), Second Affiliated Hospital, Zhejiang University, School of Medicine (1) and Xu Liu (1). The number in brackets is how many trials each organisation leads.

Where does this information come from?

Every trial, status, phase and sponsor on this page is copied from public ClinicalTrials.gov records by a daily sync. Nothing here describes how Mavacamten works or whether it is effective, and it is not medical advice.

How this page is built

Everything on this page is copied from public ClinicalTrials.gov registry records โ€” it is not written from memory, and nothing here describes how Mavacamten works or whether it is effective. Each trial links to its own record so you can check it yourself.

This page is built automatically: a daily sync job reads the registry records behind our country trial registers, collects every trial that lists Mavacamten (or a registered synonym) as a drug or biological intervention, and tabulates the registry fields directly. Placebos and generic comparators are excluded. There is no AI drafting and no per-compound editorial pass, and the page has not been clinically reviewed. The “last verified” date above is the timestamp of that sync, not a review date. Our general editorial approach is described in our editorial standards and corrections policy. The ClinicalTrials.gov data on this page was last retrieved on 25 Sep 2026.

Please verify before you rely on this. This page is general information for life-science and pharmaceutical professionals. It is not medical advice, and it has not been reviewed by a clinician โ€” our editorial team holds life-science qualifications, not clinical ones. It is not exhaustive and may not reflect the most recent label change. Always check the official prescribing information (US Prescribing Information or EU SmPC) and speak to your doctor or pharmacist before acting on anything here. Drugs in the same class are not automatically interchangeable, and approvals, brand names and indications differ between the US, the EU/Ireland (EMA/HPRA) and other regions. Spotted an error? Tell us โ€” we correct promptly and log it.