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Compound · clinical trials

Pembrolizumab KEYTRUDA clinical trials

Source: ClinicalTrials.gov, U.S. National Library of Medicine — the 5 trials in our USA, China, Ireland and UK registers that name Pembrolizumab KEYTRUDA as an intervention. Synced 25 Sep 2026
5Current trials
5Recruiting now
5Lead sponsors
4Country registers
Maintained by Sreepriya Prasannan
MSc Digital Transformation of Life Sciences (Innopharma Education / Griffith College); MSc & BSc Botany HSE Spark Ignite 2026 โ€” Top 14 finalist
Compiled from ClinicalTrials.gov registry records ยท Last verified ยท Editorial standards
At a glance

Pembrolizumab KEYTRUDA is named as an intervention in 5 current clinical trials in our USA, China, Ireland and UK registers. 5 are recruiting patients now. The most common phase is Phase 1/2. The sponsor with the most trials is Synthekine (1). The most-studied condition is Melanoma.

Trials by status

  • Recruiting5100%

Trials by phase

  • Phase 1/2480%
  • Phase 2120%
01

Clinical trials of Pembrolizumab KEYTRUDA

5 trials
StudyPhaseStatusLead sponsorRegisters
Phase II Trial of Neoadjuvant and Adjuvant IO102-IO103 and Pembrolizumab KEYTRUDAยฎ in Patients With Resectable Tumors
NCT05280314 · ClinicalTrials.gov ↗ · Melanoma, Squamous Cell Carcinoma of Head and Neck
Phase 2 Recruiting IO Biotech USA
BI-1808 as a Single Agent and With Pembrolizumab (KEYTRUDAยฎ ) in Treatment of Advanced Malignancies(Keynote-D20)
NCT04752826 · ClinicalTrials.gov ↗ · Advanced Malignancies, Ovarian Cancer, T-cell Lymphoma
Phase 1/2 Recruiting BioInvent International AB UK, USA
Study of STK-012 Alone and With Other Treatments in Patients With Advanced Lung Cancer and Other Cancers
NCT05098132 · Advanced Solid Tumor, Non Small Cell Lung Cancer, Untreated Advanced NSCLC
Phase 1/2 Recruiting Synthekine Ireland, USA
A Phase Ib/II Study of ATG-022 Plus Pembrolizumab With/Without Chemotherapy in Participants With Claudin (CLDN) 18.2-positive, HER2-negative, Unresectable or Metastatic Gastric or Gastroesophageal Junction AdenocarcinomaUnresectable or Metastatic Gastric or Gastroesophageal Junction Adenocarcinoma
NCT07327229 · ClinicalTrials.gov ↗ · Unresectable or Metastatic Gastric or Gastroesophageal Junction Adenocarcinoma
Phase 1/2 Recruiting Antengene Biologics Limited China
BC3195 in Combination With Pembrolizumab in Participants With Locally Advanced or Metastatic Solid Tumors
NCT07469774 · ClinicalTrials.gov ↗ · Locally Advanced or Metastatic Solid Tumors
Phase 1/2 Recruiting Biocity Biopharmaceutics Co., Ltd. China

Registers list studies that are recruiting, about to open, active but closed to enrolment, or enrolling by invitation. The UK and USA registers cover industry-sponsored studies only. Trial titles and statuses are copied from the registry as published.

02

Conditions studied with Pembrolizumab KEYTRUDA

11 conditions
Melanoma2Advanced Solid Tumor1Non Small Cell Lung Cancer1Untreated Advanced NSCLC11st Line NSCLC1Advanced Malignancies1Ovarian Cancer1T-cell Lymphoma1Squamous Cell Carcinoma of Head and Neck1Locally Advanced or Metastatic Solid Tumors1Unresectable or Metastatic Gastric or Gastroesophageal Junction Adenocarcinoma1
03

Sponsors

lead sponsor per trial
Lead sponsorTrials
Synthekine1
BioInvent International AB1
IO Biotech1
Biocity Biopharmaceutics Co., Ltd.1
Antengene Biologics Limited1
04

By country register

RegisterTrialsRecruiting
Clinical trials in USA33
Clinical trials in China22
Clinical trials in Ireland11
Clinical trials in UK11

A trial with sites in more than one country appears in each of those registers.

05

Related compounds

06

Questions about Pembrolizumab KEYTRUDA trials

How many clinical trials are testing Pembrolizumab KEYTRUDA?

5 current trials in our USA, China, Ireland and UK registers name Pembrolizumab KEYTRUDA as a drug or biological intervention, as of the registry sync on 25 September 2026. Completed and withdrawn studies are not counted.

Are Pembrolizumab KEYTRUDA trials recruiting patients?

Yes. 5 of the 5 trials are recruiting: 3 with sites in USA, 2 with sites in China, 1 with sites in Ireland and 1 with sites in UK. Eligibility and site contacts are on each trial's record. Only the study team can confirm whether a patient is eligible.

Who sponsors Pembrolizumab KEYTRUDA clinical trials?

Synthekine (1), BioInvent International AB (1), IO Biotech (1) and Biocity Biopharmaceutics Co., Ltd (1), among 5 lead sponsors in total. The number in brackets is how many trials each organisation leads.

Where does this information come from?

Every trial, status, phase and sponsor on this page is copied from public ClinicalTrials.gov records by a daily sync. Nothing here describes how Pembrolizumab KEYTRUDA works or whether it is effective, and it is not medical advice.

How this page is built

Everything on this page is copied from public ClinicalTrials.gov registry records โ€” it is not written from memory, and nothing here describes how Pembrolizumab KEYTRUDA works or whether it is effective. Each trial links to its own record so you can check it yourself.

This page is built automatically: a daily sync job reads the registry records behind our country trial registers, collects every trial that lists Pembrolizumab KEYTRUDA (or a registered synonym) as a drug or biological intervention, and tabulates the registry fields directly. Placebos and generic comparators are excluded. There is no AI drafting and no per-compound editorial pass, and the page has not been clinically reviewed. The “last verified” date above is the timestamp of that sync, not a review date. Our general editorial approach is described in our editorial standards and corrections policy. The ClinicalTrials.gov data on this page was last retrieved on 25 Sep 2026.

Please verify before you rely on this. This page is general information for life-science and pharmaceutical professionals. It is not medical advice, and it has not been reviewed by a clinician โ€” our editorial team holds life-science qualifications, not clinical ones. It is not exhaustive and may not reflect the most recent label change. Always check the official prescribing information (US Prescribing Information or EU SmPC) and speak to your doctor or pharmacist before acting on anything here. Drugs in the same class are not automatically interchangeable, and approvals, brand names and indications differ between the US, the EU/Ireland (EMA/HPRA) and other regions. Spotted an error? Tell us โ€” we correct promptly and log it.