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Compound · clinical trials

Ceralasertib clinical trials

Source: ClinicalTrials.gov, U.S. National Library of Medicine — the 6 trials in our UK, USA, Ireland, China and India registers that name Ceralasertib as an intervention. Synced 26 Sep 2026
6Current trials
0Recruiting now
2Lead sponsors
5Country registers
Maintained by Sreepriya Prasannan
MSc Digital Transformation of Life Sciences (Innopharma Education / Griffith College); MSc & BSc Botany HSE Spark Ignite 2026 โ€” Top 14 finalist
Compiled from ClinicalTrials.gov registry records ยท Last verified ยท Editorial standards
At a glance

Ceralasertib is named as an intervention in 6 current clinical trials in our UK, USA, Ireland, China and India registers. None are recruiting at the moment. The most common phase is Phase 2. The sponsor with the most trials is AstraZeneca (5). The most-studied condition is Advanced or Metastatic Non-Small Cell Lung Cancer.

Trials by status

  • Active, closed6100%

Trials by phase

  • Phase 2350%
  • Phase 1233%
  • Phase 3117%
01

Clinical trials of Ceralasertib

6 trials
StudyPhaseStatusLead sponsorRegisters
A Phase III Study of Ceralasertib Plus Durvalumab Versus Docetaxel in Patients With Non Small Cell Lung Cancer (NSCLC) Whose Disease Progressed On or After Prior Anti PD (L)1 Therapy And Platinum Based Chemotherapy
NCT05450692 · Advanced or Metastatic Non-Small Cell Lung Cancer
Phase 3 Active, closed AstraZeneca Ireland, UK, USA, India, China
To Assess Safety and Efficacy of Agents Targeting DNA Damage Repair With Olaparib Versus Olaparib Monotherapy.
NCT03330847 · ClinicalTrials.gov ↗ · Metastatic Triple Negative Breast Cancer
Phase 2 Active, closed AstraZeneca Ireland, UK, USA
Phase II Umbrella Study of Novel Anti-cancer Agents in Participants With NSCLC Who Progressed on an Anti-PD-1/PD-L1 Containing Therapy
NCT03334617 · ClinicalTrials.gov ↗ · Non-Small Cell Lung Cancer
Phase 2 Active, closed AstraZeneca USA
A Study of Ceralasertib Monotherapy and Ceralasertib Plus Durvalumab in Patients With Melanoma and Resistance to PD-(L)1 Inhibition
NCT05061134 · ClinicalTrials.gov ↗ · Melanoma
Phase 2 Active, closed AstraZeneca UK, USA
A Study of AZD6738 and Acalabrutinib in Subjects With Relapsed or Refractory Chronic Lymphocytic Leukemia (CLL)
NCT03328273 · ClinicalTrials.gov ↗ · Chronic Lymphocytic Leukemia
Phase 1 Active, closed Acerta Pharma BV UK
A Study to Evaluate the Safety and Pharmacokinetics of Ceralasertib in Combination With Durvalumab in Chinese Patients With Advanced Solid Tumours
NCT05514132 · ClinicalTrials.gov ↗ · Advanced Solid Tumours
Phase 1 Active, closed AstraZeneca China

Registers list studies that are recruiting, about to open, active but closed to enrolment, or enrolling by invitation. The UK and USA registers cover industry-sponsored studies only. Trial titles and statuses are copied from the registry as published.

02

Conditions studied with Ceralasertib

6 conditions
Advanced or Metastatic Non-Small Cell Lung Cancer1Metastatic Triple Negative Breast Cancer1Melanoma1Chronic Lymphocytic Leukemia1Non-Small Cell Lung Cancer1Advanced Solid Tumours1
03

Sponsors

lead sponsor per trial
Lead sponsorTrials
AstraZeneca5
Acerta Pharma BV1
04

By country register

RegisterTrialsRecruiting
Clinical trials in UK40
Clinical trials in USA40
Clinical trials in Ireland20
Clinical trials in China20
Clinical trials in India10

A trial with sites in more than one country appears in each of those registers.

05

Related compounds

06

Questions about Ceralasertib trials

How many clinical trials are testing Ceralasertib?

6 current trials in our UK, USA, Ireland, China and India registers name Ceralasertib as a drug or biological intervention, as of the registry sync on 26 September 2026. Completed and withdrawn studies are not counted.

Are Ceralasertib trials recruiting patients?

Not at the moment. None of the 6 trials in our registers is recruiting; they are active but closed to enrolment, not yet open, or enrolling by invitation. Only the study team can confirm whether a patient is eligible.

Who sponsors Ceralasertib clinical trials?

AstraZeneca (5) and Acerta Pharma BV (1). The number in brackets is how many trials each organisation leads.

Are there Ceralasertib clinical trials in Ireland?

Yes. 2 trials in our Ireland register (ClinicalTrials.gov). Some may be the same study registered in both. See the Irish clinical trials register for sites and contacts.

Where does this information come from?

Every trial, status, phase and sponsor on this page is copied from public ClinicalTrials.gov records by a daily sync. Nothing here describes how Ceralasertib works or whether it is effective, and it is not medical advice.

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How this page is built

Everything on this page is copied from public ClinicalTrials.gov registry records โ€” it is not written from memory, and nothing here describes how Ceralasertib works or whether it is effective. Each trial links to its own record so you can check it yourself.

This page is built automatically: a daily sync job reads the registry records behind our country trial registers, collects every trial that lists Ceralasertib (or a registered synonym) as a drug or biological intervention, and tabulates the registry fields directly. Placebos and generic comparators are excluded. There is no AI drafting and no per-compound editorial pass, and the page has not been clinically reviewed. The “last verified” date above is the timestamp of that sync, not a review date. Our general editorial approach is described in our editorial standards and corrections policy. The ClinicalTrials.gov data on this page was last retrieved on 26 Sep 2026.

Please verify before you rely on this. This page is general information for life-science and pharmaceutical professionals. It is not medical advice, and it has not been reviewed by a clinician โ€” our editorial team holds life-science qualifications, not clinical ones. It is not exhaustive and may not reflect the most recent label change. Always check the official prescribing information (US Prescribing Information or EU SmPC) and speak to your doctor or pharmacist before acting on anything here. Drugs in the same class are not automatically interchangeable, and approvals, brand names and indications differ between the US, the EU/Ireland (EMA/HPRA) and other regions. Spotted an error? Tell us โ€” we correct promptly and log it.