Danvatirsen clinical trials
Danvatirsen is named as an intervention in 3 current clinical trials in our USA, Spain, France, Canada, Austria, South Korea, UK, Belgium, Poland, Taiwan, Germany and Israel registers. None are recruiting at the moment. The most common phase is Phase 1. The lead sponsor is AstraZeneca. The most-studied condition is Muscle Invasive Bladder Cancer.
How Danvatirsen works
All drug targets →- STAT-3 mRNA 3'UTR antisense inhibitor Antisense inhibitorTarget: STAT3 signal transducer and activator of transcription 3ChEMBL only
- Colorectal cancerPhase 2
- Head and neck squamous cell carcinomaPhase 2
- Malignant pancreatic neoplasmPhase 2
- Non-small cell lung carcinomaPhase 2
- Ovarian cancerPhase 2
- Pancreatic neoplasmPhase 2
- Diffuse large B-cell lymphomaPhase 1/2
- Acute myeloid leukemiaPhase 1
- Hepatocellular carcinomaPhase 1
- Myelodysplastic syndromePhase 1
Mechanisms and diseases from ChEMBL via the Open Targets Platform (release 26.09), ChEMBL record CHEMBL4297739, CC BY-SA 3.0. Targets checked against the IUPHAR/BPS Guide to PHARMACOLOGY (2026.3.1), ligand 13607, CC BY-SA 4.0. Trial phases are not approvals: approved uses are shown from the regulators' own records where we hold them.
Patient leaflets for Danvatirsen
The package leaflet is the official guide for patients that comes with every medicine. These links go to the regulators that publish it.
- UKUnited Kingdom: Search MHRA ProductsPatient information leaflets and SmPCs for UK-licensed products.
- USUnited States: Search DailyMedFDA-approved labels, including patient and medication guides.
Leaflets differ between brands and countries; always read the one that comes with your own medicine. This is regulatory information, not medical advice.
Trials by status
Trials by phase
Clinical trials of Danvatirsen
3 trials| Study | Phase | Status | Lead sponsor | Registers |
|---|---|---|---|---|
|
Phase II Umbrella Study of Novel Anti-cancer Agents in Participants With NSCLC Who Progressed on an Anti-PD-1/PD-L1 Containing Therapy
NCT03334617 · Non-Small Cell Lung Cancer
|
Phase 2 | Active, closed | AstraZeneca | USA, Germany, France, Spain, Austria, Canada, South Korea, Israel |
|
Open-Label, Randomised, Multi-Drug, Biomarker-Directed, Phase 1b Study in Pts w/ Muscle Invasive Bladder Cancer
NCT02546661 · Muscle Invasive Bladder Cancer
|
Phase 1 | Active, closed | AstraZeneca | UK, USA, France, Spain, Canada |
|
A Study of Novel Anti-cancer Agents in Patients With Previously Untreated NSCLC
NCT03819465 · Metastatic Non-Small Cell Lung Cancer (NSCLC)
|
Phase 1 | Active, closed | AstraZeneca | USA, Spain, Belgium, Poland, Austria, South Korea, Taiwan |
Registers list studies that are recruiting, about to open, active but closed to enrolment, or enrolling by invitation. The UK and USA registers cover industry-sponsored studies only. Trial titles and statuses are copied from the registry as published.
Conditions studied with Danvatirsen
3 conditionsSponsors
lead sponsor per trial| Lead sponsor | Trials |
|---|---|
| AstraZeneca | 3 |
By country register
A trial with sites in more than one country appears in each of those registers.
Related compounds
Questions about Danvatirsen trials
How many clinical trials are testing Danvatirsen?
3 current trials in our USA, Spain, France, Canada, Austria, South Korea, UK, Belgium, Poland, Taiwan, Germany and Israel registers name Danvatirsen (also registered as AZD9150) as a drug or biological intervention, as of the registry sync on 9 November 2026. Completed and withdrawn studies are not counted.
Are Danvatirsen trials recruiting patients?
Not at the moment. None of the 3 trials in our registers is recruiting; they are active but closed to enrolment, not yet open, or enrolling by invitation. Only the study team can confirm whether a patient is eligible.
Who sponsors Danvatirsen clinical trials?
The lead sponsor is AstraZeneca. The number in brackets is how many trials each organisation leads.
Where does this information come from?
Every trial, status, phase and sponsor on this page is copied from public ClinicalTrials.gov records by a daily sync. Nothing here describes how Danvatirsen works or whether it is effective, and it is not medical advice.
How this page is built
Everything on this page is copied from public ClinicalTrials.gov registry records — it is not written from memory, and nothing here describes how Danvatirsen works or whether it is effective. Each trial links to its own record so you can check it yourself.
- ClinicalTrials.gov (U.S. National Library of Medicine) ↗ Trial IDs, titles, intervention names and synonyms, phase, overall status, lead sponsor and conditions for every trial on this page
This page is built automatically: a daily sync job reads the registry records behind our country trial registers, collects every trial that lists Danvatirsen (or a registered synonym) as a drug or biological intervention, and tabulates the registry fields directly. Placebos and generic comparators are excluded. There is no AI drafting and no per-compound editorial pass, and the page has not been clinically reviewed. The “last verified” date above is the timestamp of that sync, not a review date. Our general editorial approach is described in our editorial standards and corrections policy. The ClinicalTrials.gov data on this page was last retrieved on 9 Nov 2026. How every register is built: methodology · fixes we have made: corrections log.