CGRP is a peptide released during a migraine attack that dilates blood vessels and transmits pain. Blocking it was the first migraine-specific advance since the triptans. The class splits in two: monthly or quarterly antibody injections that prevent attacks, and oral "gepants" taken either to stop an attack in progress or, in some cases, to prevent them.
Class descriptions are written by the Priya Life Science editorial team. Individual drug pages combine that summary with live label, approval, manufacturer and shortage data from the U.S. FDA via the openFDA API. This page is general information and is not medical advice — it is not exhaustive, drugs within a class are not automatically interchangeable, and approvals and brand names differ between the US, EU/Ireland (EMA/HPRA) and other regions. Always consult the official prescribing information and your clinician or pharmacist. Related: Drug Shortages Tracker · FDA Approvals · All drug comparisons