What is the difference between Aimovig and Emgality?

Same class. Both Aimovig and Emgality are CGRP inhibitors, so they work through the same broad mechanism. Differences between them tend to be about dosing, route, how selective they are, and side effects rather than what they target.

Are Aimovig and Emgality the same drug?

No. Aimovig is the brand name for Erenumab and Emgality is the brand name for Galcanezumab. They are different active ingredients.

Is Aimovig a tablet or an injection?

Aimovig is given by the subcutaneous route; Emgality by the subcutaneous route.

Who makes Aimovig and Emgality?

Aimovig is marketed by Amgen; Emgality by Eli Lilly. (FDA application holder, per Drugs@FDA.)

Aimovig vs Emgality: How Erenumab and Galcanezumab Compare

At a glance

AimovigErenumab

EmgalityGalcanezumab

Brand name

Aimovig

Emgality

Drug class

CGRP receptor antagonist

CGRP inhibitor

Route

Subcutaneous

Marketed by

Amgen

Eli Lilly

First FDA approval

17 May 2018

27 Sep 2018

US shortage

Not listed

Key differences

Same class. Both Aimovig and Emgality are CGRP inhibitors, so they work through the same broad mechanism. Differences between them tend to be about dosing, route, how selective they are, and side effects rather than what they target.
How they are taken. Both are given by the subcutaneous route.
Time on the market. Aimovig was first approved by the FDA in 2018, Emgality in 2018.
Who markets them. Aimovig is marketed by Amgen; Emgality by Eli Lilly.

What each one treats

AimovigErenumab

AIMOVIG is indicated for the preventive treatment of migraine in adults. AIMOVIG is a calcitonin gene-related peptide receptor antagonist indicated for the preventive treatment of migraine in adults. ( 1 )

EmgalityGalcanezumab

EMGALITY ® is a calcitonin-gene related peptide antagonist indicated in adults for the: preventive treatment of migraine. ( 1.1 ) treatment of episodic cluster headache. ( 1.2 ) 1.1 Migraine EMGALITY is indicated for the preventive treatment of migraine in adults. 1.2 Episodic Cluster Headache EMGALITY is indicated for the treatment of episodic cluster headache in adults.

How each one works

AimovigCGRP receptor antagonist

12.1 Mechanism of Action Erenumab-aooe is a human monoclonal antibody that binds to the calcitonin gene-related peptide (CGRP) receptor and antagonizes CGRP receptor function.

EmgalityCGRP inhibitor

12.1 Mechanism of Action Galcanezumab-gnlm is a humanized monoclonal antibody that binds to calcitonin gene-related peptide (CGRP) ligand and blocks its binding to the receptor.

Related comparisons

Aimovig VS Ajovy Aimovig VS Nurtec ODT Aimovig VS Ubrelvy Emgality VS Ajovy Emgality VS Nurtec ODT Emgality VS Ubrelvy

Aimovig profile Emgality profile CGRP Inhibitors All comparisons

This is not medical advice, and not a recommendation of one drug over the other.

Which medicine is right for a given person depends on their diagnosis, other conditions, other medicines, kidney and liver function, pregnancy, and cost or reimbursement — none of which this page knows. Two drugs in the same class are not automatically interchangeable. Never start, stop or switch a prescription medicine on the basis of a web page; that decision belongs to you and your clinician or pharmacist.

Class and summary text is written by the Priya Life Science editorial team. Label, mechanism, route, manufacturer and approval data come from the U.S. FDA via the openFDA API; shortage status from the FDA Drug Shortage Database. Approvals, indications and brand names differ between the US, EU/Ireland (EMA/HPRA) and other regions — a drug approved in one may not be approved, or may carry a different name, in another.

Aimovig vs Emgality

At a glance

Key differences

What each one treats

How each one works

Related comparisons

Read more