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COVID-19 Antivirals

Also called SARS-CoV-2 antivirals, COVID treatments

These antivirals treat COVID-19 in people at high risk of severe disease, and they must be started within days of symptoms beginning to work. Paxlovid blocks the protease the virus needs to assemble itself and is the most effective of the three, but it interacts with a long list of common medicines. Remdesivir and molnupiravir instead sabotage the copying of the viral genome.

What this class is used for
COVID-19 in people at high risk of progressing to severe disease

3 COVID-19 Antivirals in this directory

Paxlovid
Nirmatrelvir/ritonavir
An oral antiviral for COVID-19 in people at risk of severe disease.
Veklury
Remdesivir
An intravenous antiviral medication used to treat patients hospitalized with severe COVID-19.
Lagevrio
Molnupiravir
An oral short-course antiviral capsule used to treat mild-to-moderate COVID-19 in high-risk adults.

Compare COVID-19 Antivirals side by side

Paxlovid VS Veklury Paxlovid VS Lagevrio Veklury VS Lagevrio

Browse other drug classes

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Class descriptions are written by the Priya Life Science editorial team. Individual drug pages combine that summary with live label, approval, manufacturer and shortage data from the U.S. FDA via the openFDA API. This page is general information and is not medical advice — it is not exhaustive, drugs within a class are not automatically interchangeable, and approvals and brand names differ between the US, EU/Ireland (EMA/HPRA) and other regions. Always consult the official prescribing information and your clinician or pharmacist. Related: Drug Shortages Tracker · FDA Approvals · All drug comparisons