IL-1 inhibitors block interleukin-1, a cytokine at the very top of the inflammatory cascade. They are the mainstay of the rare auto-inflammatory syndromes — conditions caused by an immune system that switches itself on without any infection to fight — and are also used in gout flares and certain forms of juvenile arthritis.
Class descriptions are written by the Priya Life Science editorial team. Individual drug pages combine that summary with live label, approval, manufacturer and shortage data from the U.S. FDA via the openFDA API. This page is general information and is not medical advice — it is not exhaustive, drugs within a class are not automatically interchangeable, and approvals and brand names differ between the US, EU/Ireland (EMA/HPRA) and other regions. Always consult the official prescribing information and your clinician or pharmacist. Related: Drug Shortages Tracker · FDA Approvals · All drug comparisons