IL-1 inhibitors block interleukin-1, a cytokine at the very top of the inflammatory cascade. They are the mainstay of the rare auto-inflammatory syndromes — conditions caused by an immune system that switches itself on without any infection to fight — and are also used in gout flares and certain forms of juvenile arthritis.
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Plain-English summaries and drug-class explainers are written and reviewed by the Priya Life Science editorial team, led by Sreepriya Prasannan (MSc Digital Transformation of Life Sciences (Innopharma Education / Griffith College); MSc & BSc Botany). Data is retrieved automatically from the sources above and cross-checked with AI-assisted verification (Anthropic's Claude) — brand and generic names are matched against the exact FDA product record so that a combination product or a different formulation cannot be mistaken for the drug on this page. An editor reviews the result before publication. We describe this in full in our editorial standards and corrections policy. The FDA data on this page was last retrieved on 24 Aug 2026.