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Anti-Amyloid Antibodies (Alzheimer's)

Also called amyloid-targeting antibodies, Alzheimer's disease-modifying therapy

These are the first medicines that alter the biology of Alzheimer's disease rather than just easing symptoms. Each is an antibody that binds amyloid-beta, the protein that accumulates into plaques in the brain, and clears it. They modestly slow cognitive decline in early disease — and they carry a real risk of ARIA, brain swelling and micro-bleeds that requires MRI monitoring. Their approval has been among the most contested in modern regulatory history.

Reviewed by Sreepriya Prasannan
MSc Digital Transformation of Life Sciences (Innopharma Education / Griffith College); MSc & BSc Botany HSE Spark Ignite 2026 — Top 14 finalist
Compiled from official FDA data · Last verified · Editorial standards
What this class is used for
Early Alzheimer's disease (mild cognitive impairment and mild dementia)

3 Anti-amyloid Antibodies in this directory

Leqembi
Lecanemab
An antibody that clears amyloid plaques in early Alzheimer's disease.
Kisunla
Donanemab
An intravenous biological therapy used to treat early symptomatic Alzheimer's disease by clearing brain plaque.
Aduhelm
Aducanumab
An early anti-amyloid Alzheimer's therapy.

Compare Anti-amyloid Antibodies side by side

Leqembi VS Kisunla Leqembi VS Aduhelm Kisunla VS Aduhelm

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How this page is built

The facts on this page are pulled directly from official U.S. FDA datasets — they are not written from memory. Each field below names the dataset it came from, so you can check it yourself.

Plain-English summaries and drug-class explainers are written and reviewed by Sreepriya Prasannan (MSc Digital Transformation of Life Sciences (Innopharma Education / Griffith College); MSc & BSc Botany). Data is retrieved automatically from the sources above and cross-checked with AI-assisted verification (Anthropic's Claude) — brand and generic names are matched against the exact FDA product record so that a combination product or a different formulation cannot be mistaken for the drug on this page. An editor reviews the result before publication. We describe this in full in our editorial standards and corrections policy. The FDA data on this page was last retrieved on 11 Oct 2026. How every register is built: methodology · fixes we have made: corrections log.

Please verify before you rely on this. This page is general information for life-science and pharmaceutical professionals. It is not medical advice, and it has not been reviewed by a clinician — our editorial team holds life-science qualifications, not clinical ones. It is not exhaustive and may not reflect the most recent label change. Always check the official prescribing information (US Prescribing Information or EU SmPC) and speak to your doctor or pharmacist before acting on anything here. Drugs in the same class are not automatically interchangeable, and approvals, brand names and indications differ between the US, the EU/Ireland (EMA/HPRA) and other regions. Spotted an error? Tell us — we correct promptly and log it.