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Humalog

Insulin Lispro

An injectable fast-acting insulin analogue used to manage high blood sugar levels in patients with diabetes.

Rapid-acting insulin Not in shortage
Generic name
Insulin Lispro
Brand name
Humalog
Drug class
Insulin Analog
Route
Intravenous, Subcutaneous
Manufacturer
Sanofi-Aventis U.S. LLC
First FDA approval
22 Dec 1999

What Humalog is used for

ADMELOG is indicated to improve glycemic control in adult and pediatric patients with diabetes mellitus. ADMELOG is a rapid-acting human insulin analog indicated to improve glycemic control in adult and pediatric patients with diabetes mellitus. ( 1 )

How it works

12.1 Mechanism of Action Regulation of glucose metabolism is the primary activity of insulins and insulin analogs, including insulin lispro products. Insulins lower blood glucose by stimulating peripheral glucose uptake by skeletal muscle and fat, and by inhibiting hepatic glucose production. Insulins inhibit lipolysis and proteolysis and enhance protein synthesis.

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Sources: drug label, approval and manufacturer data from the U.S. FDA via the openFDA API; shortage status from the FDA Drug Shortage Database. This page is a plain-English summary for general information and is not medical advice. It is not exhaustive and may not reflect the latest label — always consult the official prescribing information and your clinician or pharmacist. Brand availability, indications and approvals differ between the US, EU/Ireland (EMA/HPRA) and other regions.