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Priya Life Science Compound trial record
Compound · clinical trials

Rapamycin clinical trials

Also listed in trial records as Rapamune
Source: ClinicalTrials.gov, U.S. National Library of Medicine — the 23 trials in our China, USA, Australia, France, Spain, Denmark, Poland, Norway, Canada, Belgium, Netherlands and Egypt registers that name Rapamycin as an intervention. Synced 9 Nov 2026
23Current trials
16Recruiting now
22Lead sponsors
12Country registers
At a glance

Rapamycin is named as an intervention in 23 current clinical trials in our China, USA, Australia, France, Spain, Denmark, Poland, Norway, Canada, Belgium, Netherlands and Egypt registers. 16 are recruiting patients now. The most common phase is Phase 2. The sponsor with the most trials is Umoja Biopharma (2). The most-studied condition is Lymphatic Malformation.

Patient leaflets for Rapamycin

The package leaflet is the official guide for patients that comes with every medicine. These links go to the regulators that publish it.

  • UK
    United Kingdom: Search MHRA Products
    Patient information leaflets and SmPCs for UK-licensed products.
  • US
    United States: Search DailyMed
    FDA-approved labels, including patient and medication guides.

Leaflets differ between brands and countries; always read the one that comes with your own medicine. This is regulatory information, not medical advice.

Trials by status

  • Recruiting1670%
  • Not yet open417%
  • Active, closed313%

Trials by phase

  • Phase 2939%
  • Phase 3522%
  • Phase 2/3417%
  • Phase 129%
  • Phase 1/214%
  • Phase 414%
  • Not applicable14%
01

Clinical trials of Rapamycin

23 trials
StudyPhaseStatusLead sponsorRegisters
Sirolimus Monotherapy in the Treatment of Antiphospholipid Antibody Related Thrombocytopenia
NCT06722586 · ClinicalTrials.gov ↗ · Antiphospholipid (aPL)-Positive, Thrombocytopaenia
Phase 4 Recruiting Peking University First Hospital China
Systematic Approach for Children With Orbital Malformation With Sirolimus Use
NCT07378657 · ClinicalTrials.gov ↗ · Orbital Lymphatic Malformation
Phase 3 Recruiting Ain Shams University Egypt
Efficacy and Safety of Rapamycin Versus Vigabatrin in the Prevention of Tuberous Sclerosis Complex Symptoms in Infants
NCT04987463 · ClinicalTrials.gov ↗ · Tuberous Sclerosis Complex
Phase 2/3 Recruiting Katarzyna Kotulska Poland
Different Doses of Sirolimus for the Treatment of Cystic Lymphatic Malformations
NCT06673290 · ClinicalTrials.gov ↗ · Lymphatic Malformation
Phase 2/3 Recruiting West China Hospital China
Effectiveness of Alternative Therapies in Maintaining Weight Loss Achieved by GLP-1 Medications Post-Cessation
NCT07092618 · Longevity, GLP-1, Geroscience
Phase 2/3 Recruiting AgelessRx USA
Low- vs High-Dose Sirolimus With Prednisolone for KHE and KMP
NCT07656909 · ClinicalTrials.gov ↗ · Kaposiform Hemangioendothelioma (KHE), Kasabach Merritt Phenomenon
Phase 2/3 Recruiting Yi Ji China
Prospective Evaluation of the Efficacy of Sirolimus (Rapamune®) in the Treatment of Severe Arteriovenous Malformations
NCT02042326 · ClinicalTrials.gov ↗ · Arteriovenous Malformations
Phase 2 Recruiting Centre Hospitalier Universitaire, Amiens France, Belgium
Efficacy of Rapamycin in the Treatment of Cervico-facial Lymphatic Malformations
NCT03243019 · ClinicalTrials.gov ↗ · Lymphatic Malformation, Pediatric
Phase 2 Recruiting University Hospital, Lille France
Sirolimus vs Corticosteroids in Treatment of Thyroid Eye Disease
NCT04936854 · Thyroid-Associated Ophthalmopathy
Phase 2 Recruiting Haukeland University Hospital Norway
Advancing Transplantation Outcomes in Children
NCT06055608 · ClinicalTrials.gov ↗ · Kidney Transplant
Phase 2 Recruiting National Institute of Allergy and Infectious Diseases (NIAID) Canada
Hemorrhagic Brainstem Cavernous Malformations Treatment With Sirolimus: aSingle Centre, Randomized, Placebo-controlled Pilot Trial
NCT06091332 · Cavernous Malformations, Intracerebral Hemorrhage, Brainstem Stroke
Phase 2 Recruiting Huashan Hospital China
Efficacy and Safety of Sirolimus With or Without Cyclosporin A in Chinese Patients With Aplastic Anemia Refractory/Intolerant to Cyclosporin A
NCT06802055 · ClinicalTrials.gov ↗ · Aplastic Anaemia
Phase 2 Recruiting Peking Union Medical College Hospital China
A Phase 1/2 Study of UB-VV400 With Rapamycin in Relapsed/Refractory B-cell Malignancies
NCT07735533 · ClinicalTrials.gov ↗ · Lymphoma, B Cell, Lymphoma Non-Hodgkin, High Grade B Cell Lymphoma
Phase 1/2 Recruiting Umoja Biopharma USA
A Phase 1 Study of UB-VV111 With and Without Rapamycin in Relapsed/Refractory CD19+ B-cell Malignancies
NCT06528301 · Lymphoma, B-Cell, Lymphoma, Non-Hodgkin (NHL), Lymphoma, Large B-Cell, Diffuse (DLBCL)
Phase 1 Recruiting Umoja Biopharma USA, Australia
UB-VV400 in Combination With Rapamycin in Relapsed or Refractory B-cell Malignancies
NCT06743503 · ClinicalTrials.gov ↗ · Large B-cell Lymphoma
Phase 1 Recruiting Nanjing IASO Biotechnology Co., Ltd China
mTOR as Mediator of Insulin Sensitivity Study
NCT05233722 · Insulin Sensitivity
Not applicable Recruiting University of Copenhagen Denmark
Inetetamab Plus Rapamycin and Chemotherapy for HER2+ Metastatic Breast Cancer With Abnormal Activation of PAM Pathway
NCT04736589 · ClinicalTrials.gov ↗ · Breast Cancer
Phase 3 Not yet open Peking Union Medical College China
Safety Study for the Use of Rapamycin in Children With Familial Adenomatous Polyposis
NCT06308445 · ClinicalTrials.gov ↗ · Familial Adenomatous Polyposis
Phase 2 Not yet open University Hospital, Toulouse France
Rapamycin Dose-Ranging Efficacy Study in Port Wine Stains
NCT07436611 · Port Wine Stains
Phase 2 Not yet open AFT Pharmaceuticals, Ltd USA, Spain
Vaccination Response Modulation With a Targeted Rapamycin Protocol Study
NCT07587801 · ClinicalTrials.gov ↗ · Vaccine Immune Response, Haemodialysis Patients, Older Adults
Phase 2 Not yet open Central Adelaide Local Health Network Incorporated Australia
Efficacy and Safety of Sirolimus in Active Systemic Lupus Erythematosus
NCT04582136 · ClinicalTrials.gov ↗ · Systemic Lupus Erythematosus
Phase 3 Active, closed Chinese SLE Treatment And Research Group China
Phase III Trial of Sirolimus in IBM
NCT04789070 · ClinicalTrials.gov ↗ · Inclusion Body Myositis
Phase 3 Active, closed University of Kansas Medical Center Netherlands, Australia
Topical Sirolimus in Chemoprevention of Facial Squamous Cell Carcinomas in Solid Organ Transplant Recipients (SiroSkin)
NCT05860881 · ClinicalTrials.gov ↗ · Solid Organ Transplant Recipients, Skin Cancer
Phase 3 Active, closed Melanoma and Skin Cancer Trials Limited Australia

Registers list studies that are recruiting, about to open, active but closed to enrolment, or enrolling by invitation. The UK and USA registers cover industry-sponsored studies only. Trial titles and statuses are copied from the registry as published.

02

Conditions studied with Rapamycin

39 conditions
Lymphatic Malformation2Port Wine Stains1Longevity1GLP-11Geroscience1Aging1Lymphoma, B-Cell1Lymphoma, Non-Hodgkin (NHL)1Lymphoma, Large B-Cell, Diffuse (DLBCL)1Chronic Lymphocytic Leukemia (CLL)1Lymphoma, B Cell1Lymphoma Non-Hodgkin1
All 39 conditions
Condition (as registered)Trials
Lymphatic Malformation2
Port Wine Stains1
Longevity1
GLP-11
Geroscience1
Aging1
Lymphoma, B-Cell1
Lymphoma, Non-Hodgkin (NHL)1
Lymphoma, Large B-Cell, Diffuse (DLBCL)1
Chronic Lymphocytic Leukemia (CLL)1
Lymphoma, B Cell1
Lymphoma Non-Hodgkin1
High Grade B Cell Lymphoma1
Richter Transformation Lymphoma1
Breast Cancer1
Systemic Lupus Erythematosus1
Antiphospholipid (aPL)-Positive1
Thrombocytopaenia1
Cavernous Malformations1
Intracerebral Hemorrhage1
Brainstem Stroke1
Large B-cell Lymphoma1
Pediatric1
Familial Adenomatous Polyposis1
Insulin Sensitivity1
Tuberous Sclerosis Complex1
Thyroid-Associated Ophthalmopathy1
Kidney Transplant1
Solid Organ Transplant Recipients1
Skin Cancer1
Vaccine Immune Response1
Haemodialysis Patients1
Older Adults1
Kaposiform Hemangioendothelioma (KHE)1
Kasabach Merritt Phenomenon1
Aplastic Anaemia1
Arteriovenous Malformations1
Inclusion Body Myositis1
Orbital Lymphatic Malformation1
05

Related compounds

06

Questions about Rapamycin trials

How many clinical trials are testing Rapamycin?

23 current trials in our China, USA, Australia, France, Spain, Denmark, Poland, Norway, Canada, Belgium, Netherlands and Egypt registers name Rapamycin as a drug or biological intervention, as of the registry sync on 9 November 2026. Completed and withdrawn studies are not counted.

Are Rapamycin trials recruiting patients?

Yes. 16 of the 23 trials are recruiting: 6 with sites in China, 3 with sites in USA, 1 with sites in Australia, 2 with sites in France, 1 with sites in Denmark, 1 with sites in Poland, 1 with sites in Norway, 1 with sites in Canada, 1 with sites in Belgium and 1 with sites in Egypt. Eligibility and site contacts are on each trial's record. Only the study team can confirm whether a patient is eligible.

Who sponsors Rapamycin clinical trials?

Umoja Biopharma (2), AFT Pharmaceuticals, Ltd (1), AgelessRx (1) and Peking Union Medical College (1), among 22 lead sponsors in total. The number in brackets is how many trials each organisation leads.

Where does this information come from?

Every trial, status, phase and sponsor on this page is copied from public ClinicalTrials.gov records by a daily sync. Nothing here describes how Rapamycin works or whether it is effective, and it is not medical advice.

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How this page is built

Everything on this page is copied from public ClinicalTrials.gov registry records — it is not written from memory, and nothing here describes how Rapamycin works or whether it is effective. Each trial links to its own record so you can check it yourself.

This page is built automatically: a daily sync job reads the registry records behind our country trial registers, collects every trial that lists Rapamycin (or a registered synonym) as a drug or biological intervention, and tabulates the registry fields directly. Placebos and generic comparators are excluded. There is no AI drafting and no per-compound editorial pass, and the page has not been clinically reviewed. The “last verified” date above is the timestamp of that sync, not a review date. Our general editorial approach is described in our editorial standards and corrections policy. The ClinicalTrials.gov data on this page was last retrieved on 9 Nov 2026. How every register is built: methodology · fixes we have made: corrections log.

Please verify before you rely on this. This page is general information for life-science and pharmaceutical professionals. It is not medical advice, and it has not been reviewed by a clinician — our editorial team holds life-science qualifications, not clinical ones. It is not exhaustive and may not reflect the most recent label change. Always check the official prescribing information (US Prescribing Information or EU SmPC) and speak to your doctor or pharmacist before acting on anything here. Drugs in the same class are not automatically interchangeable, and approvals, brand names and indications differ between the US, the EU/Ireland (EMA/HPRA) and other regions. Spotted an error? Tell us — we correct promptly and log it.