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}, { "nct_id": "NCT07789015", "title": "A Study to Understand How Nerandomilast Works in People With Active Idiopathic Inflammatory Myopathies", "status": "NOT_YET_RECRUITING", "phase": "Phase 3", "lead_sponsor": "Boehringer Ingelheim", "conditions": [ "Idiopathic Inflammatory Myopathies" ], "sites": [ "Phoenix", "Scottsdale", "Irvine", "Los Angeles", "San Francisco", "Aurora", "Fairway", "Baltimore" ], "enrollment": 270, "start_date": "2026-12-14", "registry_url": "https://clinicaltrials.gov/study/NCT07789015" }, { "nct_id": "NCT07846215", "title": "A Phase II Study of Basmisanil in Children and Adolescents With Dup15q Syndrome", "status": "NOT_YET_RECRUITING", "phase": "Phase 2", "lead_sponsor": "Newleos Therapeutics, Inc.", "conditions": [ "Dup15Q Syndrome" ], "sites": [ "Chicago" ], "enrollment": 30, "start_date": "2026-12-01", "registry_url": "https://clinicaltrials.gov/study/NCT07846215" }, { "nct_id": "NCT07227103", "title": "A Randomized, Double-Blind Controlled Comparison of NRX-101 vs. Placebo for Adults Being Treated With Robotic Transcranial Magnetic Stimulation for Treatment Resistant Depression: The SPARC-TMS Trial", "status": "RECRUITING", "phase": "Phase 2/3", "lead_sponsor": "NeuroRx, Inc.", "conditions": [ "Treatment Resistant Depression", "Treatment Resistant Depression (TRD)" ], "sites": [ "Sarasota", "West Palm Beach", "Belmont" ], "enrollment": 240, "start_date": "2026-12-01", "registry_url": "https://clinicaltrials.gov/study/NCT07227103" }, { "nct_id": "NCT07482423", "title": "XVIE to Treat Androgenetic Alopecia (AGA)", "status": "NOT_YET_RECRUITING", "phase": "Phase 1/2", "lead_sponsor": "Restore Biologics Holdings, Inc. dba Xtress\u00e9", "conditions": [ "Androgenetic Alopecia" ], "sites": [ "Orlando", "Marriottsville" ], "enrollment": 30, "start_date": "2026-12-01", "registry_url": "https://clinicaltrials.gov/study/NCT07482423" }, { "nct_id": "NCT07719608", "title": "A Pivotal Clinical Study to Evaluate the MySalvia System for the Treatment of Resistant Migraine", "status": "RECRUITING", "phase": "Not applicable", "lead_sponsor": "Salvia BioElectronics", "conditions": [ "Resistant Migraine", "Chronic Migraine Headache", "Headache (Migraine)", "Headache, Cluster" ], "sites": [ "Newnan", "Olney", "Charlotte" ], "enrollment": 150, "start_date": "2026-12-01", "registry_url": "https://clinicaltrials.gov/study/NCT07719608" }, { "nct_id": "NCT07815574", "title": "iSCIB1+ in Combination With Ipilimumab and Nivolumab as First-Line Treatment for Advanced Unresectable Melanoma", "status": "NOT_YET_RECRUITING", "phase": "Phase 3", "lead_sponsor": "Scancell Ltd", "conditions": [ "Melanoma (Skin Cancer)", "Advanced Melanoma", "Metastatic Melanoma", "Skin Cancer" ], "sites": [ "Aurora" ], "enrollment": 550, "start_date": "2026-12-01", "registry_url": "https://clinicaltrials.gov/study/NCT07815574" }, { "nct_id": "NCT07733947", "title": "A Study to Evaluate the Maintenance of Efficacy and Long-term Safety of CBL-514 Injection for Reducing Subcutaneous Fat (Stage 1)", "status": "NOT_YET_RECRUITING", "phase": "Phase 3", "lead_sponsor": "Caliway Biopharmaceuticals Co., Ltd.", "conditions": [ "Subcutaneous Fat" ], "sites": [ "Encinitas" ], "enrollment": 300, "start_date": "2026-12", "registry_url": "https://clinicaltrials.gov/study/NCT07733947" }, { "nct_id": "NCT07900633", "title": "A Study of Eloralintide (LY3841136) in Participants With Obesity or Overweight, Type 2 Diabetes, and Increased Cardiovascular Risk", "status": "NOT_YET_RECRUITING", "phase": "Phase 3", "lead_sponsor": "Eli Lilly and Company", "conditions": [ "Obesity", "Overweight", "Cardiovascular Diseases", "Diabetes Mellitus, Type 2" ], "sites": [ "Birmingham", "Huntsville", "Apache Junction", "Gilbert", "Phoenix", "Surprise", "Covina", "Escondido" ], "enrollment": 3000, "start_date": "2026-12", "registry_url": "https://clinicaltrials.gov/study/NCT07900633" }, { "nct_id": "NCT07893223", "title": "Vancomycin Exposure and Biomarker Tracking Using Real-time Monitoring of Interstitial Fluid", "status": "NOT_YET_RECRUITING", "phase": "Observational", "lead_sponsor": "Nutromics", "conditions": [ "Biomarkers", "Acute Kidney Injury", "Sepsis" ], "sites": [ "Oakland", "San Francisco", "Stanford", "New Hyde Park", "New York" ], "enrollment": 200, "start_date": "2026-12", "registry_url": "https://clinicaltrials.gov/study/NCT07893223" }, { "nct_id": "NCT06340633", "title": "SPI-1005 in Adults Receiving Cochlear Implant", "status": "RECRUITING", "phase": "Phase 2", "lead_sponsor": "Sound Pharmaceuticals, Incorporated", "conditions": [ "Hearing Loss", "Cochlear Trauma" ], "sites": [ "Iowa City", "Columbus", "Philadelphia", "Charleston", "Dallas", "Milwaukee" ], "enrollment": 40, "start_date": "2026-12", "registry_url": "https://clinicaltrials.gov/study/NCT06340633" }, { "nct_id": "NCT07213960", "title": "A Sequential Phase 2/3 Study of APL2 in Patients With Focal Segmental Glomerulosclerosis", "status": "RECRUITING", "phase": "Phase 2/3", "lead_sponsor": "Apellis Pharmaceuticals, Inc.", "conditions": [ "FSGS" ], "sites": [ "Chicago", "New York" ], "enrollment": 270, "start_date": "2026-12", "registry_url": "https://clinicaltrials.gov/study/NCT07213960" }, { "nct_id": "NCT07711093", "title": "Study of Eso-SPONGE for Treating Leaks After Upper Gastrointestinal Surgery", "status": "NOT_YET_RECRUITING", "phase": "Not applicable", "lead_sponsor": "Boston Scientific Corporation", "conditions": [ "Anastomotic Leaks" ], "sites": [ "Dallas" ], "enrollment": 74, "start_date": "2026-12", "registry_url": "https://clinicaltrials.gov/study/NCT07711093" }, { "nct_id": "NCT07687784", "title": "A Study to Test the Non-Inferiority of Ferric Bepectate IV Against Ferric Carboxymaltose in Patients With Iron Deficiency Anemia", "status": "NOT_YET_RECRUITING", "phase": "Phase 3", "lead_sponsor": "AFT Pharmaceuticals, Ltd.", "conditions": [ "Iron Deficiency Anemia (IDA)" ], "sites": [ "Coral Gables", "Melbourne", "The Villages", "Dallas", "Houston", "San Antonio", "Sugar Land" ], "enrollment": 1366, "start_date": "2026-12", "registry_url": "https://clinicaltrials.gov/study/NCT07687784" }, { "nct_id": "NCT07827612", "title": "A Study of Vepugratinib (LY3866288) in Adults With Non-Muscle Invasive Bladder Cancer and Upper Tract Urothelial Cancer", "status": "NOT_YET_RECRUITING", "phase": "Phase 2", "lead_sponsor": "Eli Lilly and Company", "conditions": [ "Urinary Bladder Neoplasms", "Urologic Neoplasms", "Receptor, Fibroblast Growth Factor, Type 3" ], "sites": [ "Myrtle Beach" ], "enrollment": 161, "start_date": "2026-12", "registry_url": "https://clinicaltrials.gov/study/NCT07827612" }, { "nct_id": "NCT07444541", "title": "ANO31905 in Combination With Chemotherapy for CLDN18.2-Positive Locally Advanced Unresectable or Metastatic Pancreatic Cancer", "status": "RECRUITING", "phase": "Phase 1/2", "lead_sponsor": "Anova Innovation Limited", "conditions": [ "Pancreatic Cancer" ], "sites": [ "Los Angeles", "Plantation", "San Antonio" ], "enrollment": 84, "start_date": "2026-12", "registry_url": "https://clinicaltrials.gov/study/NCT07444541" }, { "nct_id": "NCT07328529", "title": "Inhibition of Aggressive Behavior in Participants With Fragile X Syndrome", "status": "NOT_YET_RECRUITING", "phase": "Phase 2", "lead_sponsor": "Azevan Pharmaceuticals", "conditions": [ "Aggressive Behavior in Fragile X Syndome" ], "sites": [ "Sacramento", "Chicago", "Cincinnati" ], "enrollment": 80, "start_date": "2026-12", "registry_url": "https://clinicaltrials.gov/study/NCT07328529" }, { "nct_id": "NCT07881432", "title": "A Study of EloraTZP in Adult Participants With Obesity Without Type 2 Diabetes", "status": "NOT_YET_RECRUITING", "phase": "Phase 3", "lead_sponsor": "Eli Lilly and Company", "conditions": [ "Obesity" ], "sites": [ "Mesa", "Scottsdale", "Tucson", "Covina", "Los Angeles", "Rolling Hills Estates", "San Diego", "Santa Ana" ], "enrollment": 2115, "start_date": "2026-12", "registry_url": "https://clinicaltrials.gov/study/NCT07881432" }, { "nct_id": "NCT07809906", "title": "Study of ORM-1153 in Acute Myeloid Leukemia (AML) With CD123 Expression", "status": "NOT_YET_RECRUITING", "phase": "Phase 1", "lead_sponsor": "Orum Therapeutics USA, Inc.", "conditions": [ "CD123+ Acute Myeloid Leukemia" ], "sites": [ "Grand Rapids", "Houston" ], "enrollment": 42, "start_date": "2026-12", "registry_url": "https://clinicaltrials.gov/study/NCT07809906" }, { "nct_id": "NCT07878988", "title": "This is a Phase 1/1b Study to Evaluate the Safety and Preliminary Antitumor Activity of LTZ-232 in Participants With Advanced/Metastatic Colorectal Cancer and Other Solid Tumors", "status": "RECRUITING", "phase": "Phase 1", "lead_sponsor": "LTZ Therapeutics, Inc.", "conditions": [ "Colorectal Cancer", "Advanced/Metastatic Solid Tumor", "Solid Tumor (Phase I)", "EPCAM" ], "sites": [ "Scottsdale" ], "enrollment": 152, "start_date": "2026-12", "registry_url": "https://clinicaltrials.gov/study/NCT07878988" }, { "nct_id": "NCT07886554", "title": "LAM-001 for the Treatment of Sarcoidosis Associated Pulmonary Hypertension (SAPH)", "status": "NOT_YET_RECRUITING", "phase": "Phase 2", "lead_sponsor": "IRulya Therapeutics Inc.", "conditions": [ "Sarcoidosis Associated Pulmonary Hypertension" ], "sites": [ "Philadelphia" ], "enrollment": 60, "start_date": "2026-12", "registry_url": "https://clinicaltrials.gov/study/NCT07886554" }, { "nct_id": "NCT07738822", "title": "A Phase 1b/2a Study of Velinotamig in Adults With Relapsed/Refractory ITP and wAIHA", "status": "NOT_YET_RECRUITING", "phase": "Phase 1/2", "lead_sponsor": "Cullinan Therapeutics Inc.", "conditions": [ "Immune Thrombocytopenia (ITP)", "Warm Autoimmune Hemolytic Anemia (WAIHA)" ], "sites": [ "Webster" ], "enrollment": 72, "start_date": "2026-12", "registry_url": "https://clinicaltrials.gov/study/NCT07738822" }, { "nct_id": "NCT07217496", "title": "N-803 in Combination With Pembrolizumab and Enfortumab Vedotin for Treatment of Urothelial Cancer", "status": "NOT_YET_RECRUITING", "phase": "Phase 1", "lead_sponsor": "ImmunityBio, Inc.", "conditions": [ "Metastatic Urothelial Carcinoma", "Urothelial Carcinoma", "Locally Advanced Urothelial Carcinoma", "Urothelial Cancer" ], "sites": [ "San Francisco" ], "enrollment": 18, "start_date": "2026-12", "registry_url": "https://clinicaltrials.gov/study/NCT07217496" }, { "nct_id": "NCT07871214", "title": "A Study to Assess The Safety and Tolerability of Pumitamig-Based Therapy Administered Before Surgery in Participants With Early-Stage Non-Small Cell Lung Cancer (ROSETTA Lung-220)", "status": "NOT_YET_RECRUITING", "phase": "Phase 2", "lead_sponsor": "Bristol-Myers Squibb", "conditions": [ "Early-Stage Non-Small Cell Lung Cancer" ], "sites": [ "Long Beach", "Los Angeles", "Tampa", "Chicago", "Chestnut Hill", "Portland", "Pittsburgh", "Nashville" ], "enrollment": 80, "start_date": "2026-11-30", "registry_url": "https://clinicaltrials.gov/study/NCT07871214" }, { "nct_id": "NCT07459634", "title": "A Study of Lurbinectedin in Combination With Durvalumab for the Treatment of Participants With ES-SCLC", "status": "RECRUITING", "phase": "Phase 2", "lead_sponsor": "Jazz Pharmaceuticals", "conditions": [ "Extensive-stage Small-cell Lung Cancer" ], "sites": [ "Los Angeles", "Jacksonville", "Atlanta", "Lexington", "Rock Hill" ], "enrollment": 50, "start_date": "2026-11-30", "registry_url": "https://clinicaltrials.gov/study/NCT07459634" }, { "nct_id": "NCT07728188", "title": "A Study to Evaluate Adverse Events and Change in Disease Activity With Injected Etentamig Plus Oral Pomalidomide Versus Standard Therapies in Adults With Relapsed or Refractory Multiple Myeloma", "status": "NOT_YET_RECRUITING", "phase": "Phase 3", "lead_sponsor": "AbbVie", "conditions": [ "Relapsed or Refractory Multiple Myeloma" ], "sites": [ "Tucson", "Cerritos", "Los Angeles", "Aurora", "Washington D.C.", "Weston", "Marietta", "Chicago" ], "enrollment": 520, "start_date": "2026-11-30", "registry_url": "https://clinicaltrials.gov/study/NCT07728188" }, { "nct_id": "NCT07890233", "title": "Efficacy of an LED Mask", "status": "ENROLLING_BY_INVITATION", "phase": "Not applicable", "lead_sponsor": "Therabody, Inc.", "conditions": [ "Fine Lines and Wrinkles", "Skin Health", "Skin Tone" ], "sites": [ "Purchase" ], "enrollment": 110, "start_date": "2026-11-30", "registry_url": "https://clinicaltrials.gov/study/NCT07890233" }, { "nct_id": "NCT07386002", "title": "The GLIOMAX Study: MT027 Allogeneic CAR-T for Recurrent Glioma", "status": "NOT_YET_RECRUITING", "phase": "Phase 2", "lead_sponsor": "T-MAXIMUM Pharmaceutical Inc", "conditions": [ "Glioblastoma IDH (Isocitrate Dehydrogenase) Wildtype" ], "sites": [ "Baltimore" ], "enrollment": 40, "start_date": "2026-11-30", "registry_url": "https://clinicaltrials.gov/study/NCT07386002" }, { "nct_id": "NCT07780968", "title": "Zanidatamab Outcomes and Lived Experiences in Advanced HER2+ GEA", "status": "NOT_YET_RECRUITING", "phase": "Observational", "lead_sponsor": "Jazz Pharmaceuticals", "conditions": [ "Esophageal Cancer", "GastroEsophageal Cancer", "Gastroesophageal-junction Cancer", "HER2-positive Gastric Cancer" ], "sites": [ "Orange", "Houston" ], "enrollment": 300, "start_date": "2026-11-30", "registry_url": "https://clinicaltrials.gov/study/NCT07780968" }, { "nct_id": "NCT07717411", "title": "A Study of Trontinemab in Cognitively Unimpaired Individuals at Risk for Progression to Symptomatic Alzheimer's Disease", "status": "RECRUITING", "phase": "Phase 3", "lead_sponsor": "Hoffmann-La Roche", "conditions": [ "Alzheimer's Disease" ], "sites": [ "Irvine", "Long Beach", "Oakland", "Santa Ana", "Maitland", "Ocala", "Orlando", "The Villages" ], "enrollment": 1600, "start_date": "2026-11-30", "registry_url": "https://clinicaltrials.gov/study/NCT07717411" }, { "nct_id": "NCT07728097", "title": "A Study to Investigate the Effect of Gradual Titration to Optimize Cannabidiol Treatment in Adults With LGS", "status": "NOT_YET_RECRUITING", "phase": "Phase 4", "lead_sponsor": "Jazz Pharmaceuticals", "conditions": [ "Lennox-Gastaut Syndrome" ], "sites": [ "Fresno", "New Orleans", "Raleigh" ], "enrollment": 40, "start_date": "2026-11-18", "registry_url": "https://clinicaltrials.gov/study/NCT07728097" }, { "nct_id": "NCT07846683", "title": "A Study to Assess the Efficacy and Safety of Subcutaneous Induction Therapy With Afimkibart in Participants With Moderately to Severely Active Ulcerative Colitis", "status": "RECRUITING", "phase": "Phase 3", "lead_sponsor": "Hoffmann-La Roche", "conditions": [ "Moderately to Severely Active Ulcerative Colitis" ], "sites": [ "Cordova" ], "enrollment": 350, "start_date": "2026-11-15", "registry_url": "https://clinicaltrials.gov/study/NCT07846683" }, { "nct_id": "NCT07871071", "title": "Brain-Computer Interface Communication Device for People With ALS", "status": "RECRUITING", "phase": "Not applicable", "lead_sponsor": "Cognixion", "conditions": [ "Amyotrophic Lateral Sclerosis" ], "sites": [ "Santa Barbara" ], "enrollment": 30, "start_date": "2026-11-15", "registry_url": "https://clinicaltrials.gov/study/NCT07871071" }, { "nct_id": "NCT07436611", "title": "Rapamycin Dose-Ranging Efficacy Study in Port Wine Stains", "status": "NOT_YET_RECRUITING", "phase": "Phase 2", "lead_sponsor": "AFT Pharmaceuticals, Ltd.", "conditions": [ "Port Wine Stains" ], "sites": [ "Corpus Christi" ], "enrollment": 30, "start_date": "2026-11-13", "registry_url": "https://clinicaltrials.gov/study/NCT07436611" }, { "nct_id": "NCT07839819", "title": "Study of PM54 in Combination With Cytotoxic and Targeted Agents in Adult Participants With Advanced Malignancies", "status": "NOT_YET_RECRUITING", "phase": "Phase 1/2", "lead_sponsor": "PharmaMar", "conditions": [ "Advanced Solid Tumor" ], "sites": [ "Omaha", "Houston" ], "enrollment": 231, "start_date": "2026-11-12", "registry_url": "https://clinicaltrials.gov/study/NCT07839819" }, { "nct_id": "NCT07855900", "title": "SYNCHRONIZE\u00ae-START- A Study to Test Whether Survodutide Helps People Living With Overweight or Obesity Who do Not Have Diabetes to Lose Weight", "status": "NOT_YET_RECRUITING", "phase": "Phase 3", "lead_sponsor": "Boehringer Ingelheim", "conditions": [ "Obesity" ], "sites": [ "Riverview", "Macon" ], "enrollment": 350, "start_date": "2026-11-07", "registry_url": "https://clinicaltrials.gov/study/NCT07855900" }, { "nct_id": "NCT07773727", "title": "A Study to Evaluate the Effect of ARGX-121 on the Change in Proteinuria in Adult Participants With IgAN", "status": "RECRUITING", "phase": "Phase 2", "lead_sponsor": "argenx", "conditions": [ "Immunoglobulin A Nephropathy (IgAN)" ], "sites": [ "Valencia", "Miami", "Pembroke Pines", "Pontiac", "Houston", "Salt Lake City", "Manassas" ], "enrollment": 120, "start_date": "2026-11-05", "registry_url": "https://clinicaltrials.gov/study/NCT07773727" }, { "nct_id": "NCT07887763", "title": "A Phase 1 Study to Evaluate Safety, Tolerability, and Drug Levels of BMS-986485 in Healthy Adult Participants", "status": "NOT_YET_RECRUITING", "phase": "Phase 1", "lead_sponsor": "Bristol-Myers Squibb", "conditions": [ "Healthy Volunteers" ], "sites": [ "Salt Lake City" ], "enrollment": 50, "start_date": "2026-11-03", "registry_url": "https://clinicaltrials.gov/study/NCT07887763" }, { "nct_id": "NCT07850063", "title": "ELEVATE-LIVER: A Study to Test Whether Survodutide Helps Improve Heart Structure and Function in People With Overweight or Obesity and Fatty Liver Disease", "status": "NOT_YET_RECRUITING", "phase": "Phase 3", "lead_sponsor": "Boehringer Ingelheim", "conditions": [ "Obesity", "Metabolic Dysfunction-associated Steatotic Liver Disease" ], "sites": [ "Peoria", "Los Angeles", "Oxnard", "Pasadena", "West Hills", "University Park", "Kansas City", "Topeka" ], "enrollment": 600, "start_date": "2026-11-02", "registry_url": "https://clinicaltrials.gov/study/NCT07850063" }, { "nct_id": "NCT07894081", "title": "Evaluation of Gixam's Repeatability and Reproducibility Predicting the Presence of Advanced and Non-Advanced Colorectal Neoplasia", "status": "NOT_YET_RECRUITING", "phase": "Not applicable", "lead_sponsor": "Jubaan Ltd.", "conditions": [ "CRC Screening" ], "sites": [ "Orlando" ], "enrollment": 120, "start_date": "2026-11-02", "registry_url": "https://clinicaltrials.gov/study/NCT07894081" }, { "nct_id": "NCT07875270", "title": "Usability and Clinical Validation of the Flu A/B/COVID-19 + RSV Multiplex Rapid Test", "status": "NOT_YET_RECRUITING", "phase": "Not applicable", "lead_sponsor": "CorDx, Inc.", "conditions": [ "SARS-CoV-2 Infection", "Influenza A", "Influenza B", "RSV" ], "sites": [ "Alpharetta" ], "enrollment": 1500, "start_date": "2026-11-01", "registry_url": "https://clinicaltrials.gov/study/NCT07875270" }, { "nct_id": "NCT07462052", "title": "Talk Parenting Education Program II", "status": "NOT_YET_RECRUITING", "phase": "Not applicable", "lead_sponsor": "Oregon Research Behavioral Intervention Strategies, Inc.", "conditions": [ "Parenting Practices", "Self Efficacy", "Stress", "Child Behavior" ], "sites": [ "Springfield" ], "enrollment": 184, "start_date": "2026-11-01", "registry_url": "https://clinicaltrials.gov/study/NCT07462052" }, { "nct_id": "NCT07673744", "title": "A Study to Evaluate the Efficacy and Safety of Maintenance Ublituximab Following Induction With Efgartigimod Administration in Participants With Myasthenia Gravis (MG)", "status": "RECRUITING", "phase": "Phase 2", "lead_sponsor": "TG Therapeutics, Inc.", "conditions": [ "Myasthenia Gravis" ], "sites": [ "Colorado Springs", "Clearwater", "Maitland", "Farmington Hills", "New Bern", "Greenville" ], "enrollment": 120, "start_date": "2026-11-01", "registry_url": "https://clinicaltrials.gov/study/NCT07673744" }, { "nct_id": "NCT07712003", "title": "Natural History to Assess Disease in Patients With MPS IIIC", "status": "NOT_YET_RECRUITING", "phase": "Observational", "lead_sponsor": "Phoenix Nest", "conditions": [ "Sanfilippo Syndrome Type C", "Mucopolysaccharidosis (MPS) IIIC" ], "sites": [ "Dallas" ], "enrollment": 35, "start_date": "2026-11-01", "registry_url": "https://clinicaltrials.gov/study/NCT07712003" }, { "nct_id": "NCT07455084", "title": "A Study to Detect the Radioactivity of 14C-SEP-380135 in Urine and Feces in Healthy Male Adults", "status": "NOT_YET_RECRUITING", "phase": "Phase 1", "lead_sponsor": "Otsuka Pharmaceutical Development & Commercialization, Inc.", "conditions": [ "Schizophrenia" ], "sites": [ "Lincoln" ], "enrollment": 8, "start_date": "2026-11-01", "registry_url": "https://clinicaltrials.gov/study/NCT07455084" }, { "nct_id": "NCT07856121", "title": "The Precision Mito- Mito Map COMPASS Study", "status": "NOT_YET_RECRUITING", "phase": "Observational", "lead_sponsor": "AI Agent Vault, Inc. d/b/a Precision Mito", "conditions": [ "Mitochondrial Diseases", "Myalgic 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Neuro Inc.", "conditions": [ "Dyslexia", "Reading Disability" ], "sites": [ "Boston" ], "enrollment": 60, "start_date": "2026-11-01", "registry_url": "https://clinicaltrials.gov/study/NCT07762365" }, { "nct_id": "NCT07796763", "title": "A Global Trial of Trastuzumab Rezetecan (SHR-A1811) in Combination With Chemotherapy and Bevacizumab as First-Line Treatment in Patients With Advanced Colorectal Cancer Expressing HER2", "status": "NOT_YET_RECRUITING", "phase": "Phase 2", "lead_sponsor": "Jiangsu HengRui Medicine Co., Ltd.", "conditions": [ "Advanced Colorectal Cancer Expressing HER2" ], "sites": [ "Houston" ], "enrollment": 48, "start_date": "2026-11-01", "registry_url": "https://clinicaltrials.gov/study/NCT07796763" }, { "nct_id": "NCT07883590", "title": "A Study of LY3873862 in Participants With Sporadic or Familial Amyotrophic Lateral Sclerosis (ALS).", "status": "NOT_YET_RECRUITING", "phase": "Phase 1", "lead_sponsor": "Eli Lilly and Company", "conditions": [ "Amyotrophic Lateral Sclerosis", "Cytochrome P-450 Enzyme System" ], "sites": [ "San Francisco", "Aurora", "Kansas City" ], "enrollment": 32, "start_date": "2026-11", "registry_url": "https://clinicaltrials.gov/study/NCT07883590" }, { "nct_id": "NCT07574918", "title": "Measuring Nasal Airway Changes After VivAer Treatment Using AI Analysis", "status": "RECRUITING", "phase": "Not applicable", "lead_sponsor": "Aerin Medical", "conditions": [ "Nasal Airway Obstruction" ], "sites": [ "Newark" ], "enrollment": 30, "start_date": "2026-11", "registry_url": "https://clinicaltrials.gov/study/NCT07574918" }, { "nct_id": "NCT07806773", "title": "Study of TUB-040 in Participants With Unresectable or Metastatic Nonsquamous Non-small Cell Lung Cancer", "status": "NOT_YET_RECRUITING", "phase": "Phase 2", "lead_sponsor": "Gilead Sciences", "conditions": [ "NSCLC", "Non Small Cell Lung Cancer" ], "sites": [ "Los Angeles", "East Brunswick" ], "enrollment": 80, "start_date": "2026-11", "registry_url": "https://clinicaltrials.gov/study/NCT07806773" }, { "nct_id": "NCT07897760", "title": "Evaluating the Effects of the EXOPULSE Suit on Mobility, Walking Ability, and Balance in People With Multiple Sclerosis", "status": "NOT_YET_RECRUITING", "phase": "Not applicable", "lead_sponsor": "Otto Bock Healthcare Products GmbH", "conditions": [ "Multiple Sclerosis" ], "sites": [ "Chicago" ], "enrollment": 100, "start_date": "2026-11", "registry_url": "https://clinicaltrials.gov/study/NCT07897760" }, { "nct_id": "NCT07872644", "title": "Safety in Ovarian Cancer for Average-Risk Women - Analysis", "status": "NOT_YET_RECRUITING", "phase": "Not applicable", "lead_sponsor": "Mercy BioAnalytics, Inc.", "conditions": [ "Ovarian Cancer" ], "sites": [ "Waltham", "Austin" ], "enrollment": 1750, "start_date": "2026-11", "registry_url": "https://clinicaltrials.gov/study/NCT07872644" }, { "nct_id": "NCT06267248", "title": "Spine Registration Using 3D-Scanning", "status": "ENROLLING_BY_INVITATION", "phase": "Observational", "lead_sponsor": "Advanced Scanners Inc.", "conditions": [ "Spine Surgery" ], "sites": [ "Boston" ], "enrollment": 10, "start_date": "2026-11", "registry_url": "https://clinicaltrials.gov/study/NCT06267248" }, { "nct_id": "NCT07738939", "title": "IKS04 Regimen in Advanced Solid Tumors That Express CA242", "status": "NOT_YET_RECRUITING", "phase": "Phase 1", "lead_sponsor": "Iksuda Therapeutics Ltd.", "conditions": [ "Colorectal Cancer", "Gastro Esophageal Junctional Cancer", "Gastric Cancer (GC)", "GEJ Adenocarcinoma" ], "sites": [ "Los Angeles", "Boston", "Nashville", "Houston" ], "enrollment": 120, "start_date": "2026-11", "registry_url": "https://clinicaltrials.gov/study/NCT07738939" }, { "nct_id": "NCT07887971", "title": "A Study of [225Ac]Ac-AKY-2519 in Patients With B7-H3 Expressing Solid Tumors", "status": "RECRUITING", "phase": "Phase 1", "lead_sponsor": "Aktis Oncology, Inc.", "conditions": [ "NSCLC", "NSCLC (Advanced Non-small Cell Lung Cancer)", "ES-SCLC", "Small Cell Lung Cancer Extensive Stage" ], "sites": [ "Miami" ], "enrollment": 152, "start_date": "2026-11", "registry_url": "https://clinicaltrials.gov/study/NCT07887971" }, { "nct_id": "NCT07853716", "title": "REFINE-CAC Protocol: Risk Evaluation With AI-CPA + HCS For Patients IN Whom Calcium is confirmEd to Improve Coronary Artery Disease Care", "status": "NOT_YET_RECRUITING", "phase": "Not applicable", "lead_sponsor": "HeartFlow, Inc.", "conditions": [ "CAD - Coronary Artery Disease" ], "sites": [ "New York" ], "enrollment": 500, "start_date": "2026-11", "registry_url": "https://clinicaltrials.gov/study/NCT07853716" }, { "nct_id": "NCT07703046", "title": "Sperm, Exposure and Endocrine Disruptors", "status": "NOT_YET_RECRUITING", "phase": "Not applicable", "lead_sponsor": "Million Marker Wellness, Inc.", "conditions": [ "Fertility", "Male Fertility", "Sperm Count, Low", "Sperm Quality" ], "sites": [ "Berkeley" ], "enrollment": 100, "start_date": "2026-11", "registry_url": "https://clinicaltrials.gov/study/NCT07703046" }, { "nct_id": "NCT07870590", "title": "GV101 for Friedreich's Ataxia (FA) Treatment", "status": "NOT_YET_RECRUITING", "phase": "Phase 2", "lead_sponsor": "Graviton Bioscience Corporation", "conditions": [ "Friedreich's Ataxia" ], "sites": [ "Eatontown" ], "enrollment": 48, "start_date": "2026-11", "registry_url": "https://clinicaltrials.gov/study/NCT07870590" }, { "nct_id": "NCT07885033", "title": "Oral Care Program for Mouth Side Effects During Head and Neck Radiation Therapy", "status": "NOT_YET_RECRUITING", "phase": "Not applicable", "lead_sponsor": "UNCANCER LLC", "conditions": [ "Head and Neck Cancer (H&N)", "Oral Mucositis (Ulcerative) Due to Radiation", "Stomatitis (Oral Mucositis)", "Xerostomia Due to Radiotherapy" ], "sites": [ "Clearwater" ], "enrollment": 50, "start_date": "2026-11", "registry_url": "https://clinicaltrials.gov/study/NCT07885033" }, { "nct_id": "NCT07881458", "title": "A Study of EloraTZP in Adult Participants With Obesity or Overweight and Type 2 Diabetes", "status": "NOT_YET_RECRUITING", "phase": "Phase 3", "lead_sponsor": "Eli Lilly and Company", "conditions": [ "Obesity", "Overweight", "Diabetes Mellitus, Type 2" ], "sites": [ "Tucson", "Los Alamitos", "Los Angeles", "Aurora", "Pembroke Pines", "Weston", "Dalton", "Honolulu" ], "enrollment": 1000, "start_date": "2026-11", "registry_url": "https://clinicaltrials.gov/study/NCT07881458" }, { "nct_id": "NCT07890376", "title": "A Study to Investigate the Effect of LY4086940 Versus Placebo in Participants With Obesity or Overweight and Without Type 2 Diabetes", "status": "NOT_YET_RECRUITING", "phase": "Phase 2", "lead_sponsor": "Eli Lilly and Company", "conditions": [ "Obesity", "Overweight" ], "sites": [ "Chandler", "Scottsdale", "Tucson", "Greenbrae", "Huntington Park", "Rolling Hills Estates", "Walnut Creek", "Stamford" ], "enrollment": 460, "start_date": "2026-11", "registry_url": "https://clinicaltrials.gov/study/NCT07890376" }, { "nct_id": "NCT07215403", "title": "Open-Label, Multi-Stage Study to Optimize the Intraputaminal Administration of AB-1005 Using a Prescriptive Infusion Algorithm (PIA)", "status": "NOT_YET_RECRUITING", "phase": "Phase 2", "lead_sponsor": "AskBio Inc", "conditions": [ "PARKINSON DISEASE (Disorder)" ], "sites": [ "Cleveland", "Columbus", "Pittsburgh", "Charleston" ], "enrollment": 18, "start_date": "2026-11", "registry_url": "https://clinicaltrials.gov/study/NCT07215403" }, { "nct_id": "NCT07653815", "title": "Essential Oil-Based Product System for Digestive Support", "status": "NOT_YET_RECRUITING", "phase": "Not applicable", "lead_sponsor": "d\u014dTERRA International", "conditions": [ "Healthy" ], "sites": [ "Pleasant Grove" ], "enrollment": 40, "start_date": "2026-11", "registry_url": "https://clinicaltrials.gov/study/NCT07653815" }, { "nct_id": "NCT07035431", "title": "Endo-SPONGE for Treatment of Anastomotic or Hartmann's Stump Leakages in Lower Pelvic Area", "status": "RECRUITING", "phase": "Not applicable", "lead_sponsor": "Boston Scientific Corporation", "conditions": [ "Anastomotic Leaks", "Hartmanns Stump Leakage" ], "sites": [ "Sacramento", "Orlando", "Weston", "Burlington", "New York", "Cleveland", "Hershey", "Philadelphia" ], "enrollment": 66, "start_date": "2026-11", "registry_url": "https://clinicaltrials.gov/study/NCT07035431" }, { "nct_id": "NCT07868510", "title": "Kore Fiber PLF Study", "status": "NOT_YET_RECRUITING", "phase": "Not applicable", "lead_sponsor": "Kolosis Bio, LLC", "conditions": [ "Degenerative Lumbar Spine Diseases", "Lumbar Degenerative Disc Disease", "Lumbar Spinal Stenosis", "Spondylolisthesis" ], "sites": [ "Columbus" ], "enrollment": 75, "start_date": "2026-11", "registry_url": "https://clinicaltrials.gov/study/NCT07868510" }, { "nct_id": "NCT06531031", "title": "Clinical Performance Study of Microbio InfectID-BSI for Detection of Bacteria and Yeast With Patient Blood Samples", "status": "NOT_YET_RECRUITING", "phase": "Observational", "lead_sponsor": "Microbio Co Ltd", "conditions": [ "Bloodstream Infection", "Sepsis", "Septic Shock" ], "sites": [ "Indianapolis", "Baltimore", "Albuquerque", "Nashville", "Houston" ], "enrollment": 1500, "start_date": "2026-11", "registry_url": "https://clinicaltrials.gov/study/NCT06531031" }, { "nct_id": "NCT07887425", "title": "Corneal Trauma Diagnostic Study", "status": "RECRUITING", "phase": "Not applicable", "lead_sponsor": "InnSight Technology, Inc.", "conditions": [ "Ocular Trauma" ], "sites": [ "Pittsburgh" ], "enrollment": 40, "start_date": "2026-11", "registry_url": "https://clinicaltrials.gov/study/NCT07887425" }, { "nct_id": "NCT07838077", "title": "Modified SOLTIVE Study", "status": "NOT_YET_RECRUITING", "phase": "Observational", "lead_sponsor": "Olympus Corporation of the Americas", "conditions": [ "Calculi, Renal", "Calculi, Urinary", "Benign Prostatic Hyperplasia" ], "sites": [ "Kansas City" ], "enrollment": 250, "start_date": "2026-11", "registry_url": "https://clinicaltrials.gov/study/NCT07838077" }, { "nct_id": "NCT07898995", "title": "Clinical Performance and Outcomes After Toric Lens Transition", "status": "NOT_YET_RECRUITING", "phase": "Not applicable", "lead_sponsor": "CooperVision International Limited (CVIL)", "conditions": [ "Astigmatism" ], "sites": [ "Bloomington" ], "enrollment": 35, "start_date": "2026-11", "registry_url": "https://clinicaltrials.gov/study/NCT07898995" }, { "nct_id": "NCT07224763", "title": "Study to Evaluate the Safety and Efficacy of the GGTA1 KO Thymokidney in Patients With ESRD", "status": "RECRUITING", "phase": "Phase 1/2", "lead_sponsor": "United Therapeutics", "conditions": [ "ESRD (End-Stage Renal Disease)", "Kidney Transplantation", "Xenotransplantation" ], "sites": [ "New York" ], "enrollment": 50, "start_date": "2026-11", "registry_url": "https://clinicaltrials.gov/study/NCT07224763" }, { "nct_id": "NCT07477054", "title": "A Post-Approval Multicenter Study to Assess the Continued Safety and Effectiveness of the AeroPace\u00ae System", "status": "RECRUITING", "phase": "Not applicable", "lead_sponsor": "Lungpacer Medical Inc.", "conditions": [ "Ventilator Induced Diaphragm Dysfunction" ], "sites": [ "San Francisco" ], "enrollment": 120, "start_date": "2026-10-31", "registry_url": "https://clinicaltrials.gov/study/NCT07477054" }, { "nct_id": "NCT07632937", "title": "A Study to Assess the Efficacy of Public Health Campaigns in Reducing Lead Exposure", "status": "NOT_YET_RECRUITING", "phase": "Not applicable", "lead_sponsor": "International Health Strategies LLC", "conditions": [ "Lead Poisoning", "Environmental Exposure" ], "sites": [ "Philadelphia" ], "enrollment": 400, "start_date": "2026-10-31", "registry_url": "https://clinicaltrials.gov/study/NCT07632937" }, { "nct_id": "NCT07222553", "title": "Study to Evaluate the Pharmacokinetics, Pharmacodynamics, Safety, and Tolerability of Inebilizumab in Pediatric Participants With IgG4-RD", "status": "NOT_YET_RECRUITING", "phase": "Phase 2", "lead_sponsor": "Amgen", "conditions": [ "Immunoglobulin G4-related Disease" ], "sites": [ "Tampa", "Chapel Hill", "Pittsburgh" ], "enrollment": 15, "start_date": "2026-10-31", "registry_url": "https://clinicaltrials.gov/study/NCT07222553" }, { "nct_id": "NCT07781657", "title": "Study to Test Effects and Safety of RO7568282 in Early Symptomatic Alzheimer's Disease", "status": "NOT_YET_RECRUITING", "phase": "Phase 2", "lead_sponsor": "Hoffmann-La Roche", "conditions": [ "Alzheimer's Disease" ], "sites": [ "Laurelton" ], "enrollment": 450, "start_date": "2026-10-31", "registry_url": "https://clinicaltrials.gov/study/NCT07781657" }, { "nct_id": "NCT07301346", "title": "EASEE\u00ae System Pivotal Study for the United States of America", "status": "NOT_YET_RECRUITING", "phase": "Not applicable", "lead_sponsor": "Precisis US, Inc.", "conditions": [ "Drug-Resistant Focal Epilepsy" ], "sites": [ "New York" ], "enrollment": 200, "start_date": "2026-10-31", "registry_url": "https://clinicaltrials.gov/study/NCT07301346" }, { "nct_id": "NCT07444450", "title": "A Study to Learn About the Safety and Effects of Salanersen (BIIB115) When Given to Babies With Spinal Muscular Atrophy (SMA) Who Were Previously Treated With Onasemnogene Abeparvovec", "status": "RECRUITING", "phase": "Phase 3", "lead_sponsor": "Biogen", "conditions": [ "Muscular Atrophy, Spinal" ], "sites": [ "Flower Mound" ], "enrollment": 42, "start_date": "2026-10-31", "registry_url": "https://clinicaltrials.gov/study/NCT07444450" }, { "nct_id": "NCT07850050", "title": "SYNCHRONIZE\u00ae-HERA: A Study to Test Whether Survodutide Helps Women Who Are Living With Overweight or Obesity and Are Going Through or Have Finished Menopause, to Lose Weight", "status": "NOT_YET_RECRUITING", "phase": "Phase 3", "lead_sponsor": "Boehringer Ingelheim", "conditions": [ "Obesity" ], "sites": [ "Birmingham", "Northridge", "Orange", "Walnut Creek", "Fort Lauderdale", "Jacksonville", "Merritt Island", "Ocoee" ], "enrollment": 600, "start_date": "2026-10-31", "registry_url": "https://clinicaltrials.gov/study/NCT07850050" }, { "nct_id": "NCT07542314", "title": "Study to Evaluate the Safety and Effectiveness of ELEVIDYS in Participants With Duchenne Muscular Dystrophy Treated in a Post-Marketing Setting", "status": "RECRUITING", "phase": "Phase 4", "lead_sponsor": "Sarepta Therapeutics, Inc.", "conditions": [ "Duchenne Muscular Dystrophy" ], "sites": [ "Houston" ], "enrollment": 20, "start_date": "2026-10-30", "registry_url": "https://clinicaltrials.gov/study/NCT07542314" }, { "nct_id": "NCT07849387", "title": "Sacrum Pressure Injury Prevention Study Using ALLEVYN\u25ca Complete Care in Adults at Risk of Developing Hospital-acquired Pressure Injuries in Critical Care Units", "status": "NOT_YET_RECRUITING", "phase": "Not applicable", "lead_sponsor": "Smith & Nephew, Inc.", "conditions": [ "Pressure Ulcers (Hospital-acquired Pressure Injuries)" ], "sites": [ "Grand Junction", "Atlanta", "Indianapolis" ], "enrollment": 330, "start_date": "2026-10-30", "registry_url": "https://clinicaltrials.gov/study/NCT07849387" }, { "nct_id": "NCT07899814", "title": "Utilizing RENASYS\u25ca DYNAFLOW Instillation Therapy System for Wound Management in Adults With Acute and Chronic Wounds", "status": "NOT_YET_RECRUITING", "phase": "Not applicable", "lead_sponsor": "Smith & Nephew, Inc.", "conditions": [ "Wounds and Injuries" ], "sites": [ "Saint Paul" ], "enrollment": 25, "start_date": "2026-10-30", "registry_url": "https://clinicaltrials.gov/study/NCT07899814" }, { "nct_id": "NCT07748208", "title": "A Study Evaluating the Safety of Inavolisib and Fulvestrant With or Without Palbociclib in Participants With Advanced Breast Cancer (ABC) and Type 2 Diabetes", "status": "RECRUITING", "phase": "Phase 2", "lead_sponsor": "Hoffmann-La Roche", "conditions": [ "Breast Cancer", "Diabetes Type II" ], "sites": [ "Washington D.C.", "Atlanta", "Grand Island", "Omaha", "Mineola", "New York", "Morgantown" ], "enrollment": 40, "start_date": "2026-10-30", "registry_url": "https://clinicaltrials.gov/study/NCT07748208" }, { "nct_id": "NCT07473700", "title": "Study of TX000045 in Participants With Pulmonary Hypertension Due to Interstitial Lung Disease", "status": "RECRUITING", "phase": "Phase 2", "lead_sponsor": "Tectonic Operating Company, Inc.", "conditions": [ "Hypertension, Pulmonary", "Lung Diseases, Interstitial" ], "sites": [ "Phoenix", "San Francisco", "Boise", "Allen Park" ], "enrollment": 25, "start_date": "2026-10-30", "registry_url": "https://clinicaltrials.gov/study/NCT07473700" }, { "nct_id": "NCT07875101", "title": "Assessing the Potential for Improved Joint Health and Wellbeing by Providing a Whole Salmon Oil With Undenatured Type II Collagen Compared to Type II Collagen Alone", "status": "NOT_YET_RECRUITING", "phase": "Not applicable", "lead_sponsor": "Hofseth Biocare ASA", "conditions": [ "Joint Discomfort", "Wellbeing", "Quality of Life" ], "sites": [ "San Francisco" ], "enrollment": 150, "start_date": "2026-10-30", "registry_url": "https://clinicaltrials.gov/study/NCT07875101" }, { "nct_id": "NCT07683325", "title": "NOV-ERA - A Clinical Trial to Assess the Efficacy and Safety of Ontunisertib Compared to Placebo in Patients With Fibrostenosing Crohn's Disease", "status": "RECRUITING", "phase": "Phase 2", "lead_sponsor": "Agomab Spain S.L.U.", "conditions": [ "Fibrostenotic Crohn's Disease" ], "sites": [ "Sun City", "Bradenton", "Albany", "Providence", "Cedar Park", "Fort Worth", "Georgetown" ], "enrollment": 320, "start_date": "2026-10-30", "registry_url": "https://clinicaltrials.gov/study/NCT07683325" }, { "nct_id": "NCT07788989", "title": "A Study to Predict Atrial Fibrillation (AF) Burden in Participants With PAF and PsAF Treated With the VARIPULSE\u2122 PFA Catheter", "status": "NOT_YET_RECRUITING", "phase": "Not applicable", "lead_sponsor": "Biosense Webster, Inc.", "conditions": [ "Atrial Fibrillation" ], "sites": [ "Austin" ], "enrollment": 2300, "start_date": "2026-10-30", "registry_url": "https://clinicaltrials.gov/study/NCT07788989" }, { "nct_id": "NCT07890584", "title": "A Study of PLS240 in Pediatric Participants With Secondary Hyperparathyroidism and Chronic Kidney Disease on Hemodialysis", "status": "NOT_YET_RECRUITING", "phase": "Phase 3", "lead_sponsor": "Pathalys Pharma", "conditions": [ "Chronic Kidney Disease (CKD)", "Secondary Hyperparathyroidism" ], "sites": [ "Buffalo" ], "enrollment": 56, "start_date": "2026-10-30", "registry_url": "https://clinicaltrials.gov/study/NCT07890584" }, { "nct_id": "NCT07873931", "title": "A Study of BMS-986553 in Participants With Refractory Autoimmune Diseases", "status": "NOT_YET_RECRUITING", "phase": "Phase 1", "lead_sponsor": "Bristol-Myers Squibb", "conditions": [ "Systemic Lupus Erythematosus", "Sj\u00f6gren's Disease", "Rheumatoid Arthritis", "Idiopathic Inflammatory Myopathies" ], "sites": [ "Newport Beach", "Worcester", "Ann Arbor", "Saint Paul", "Omaha", "Morristown", "Great Neck", "Philadelphia" ], "enrollment": 60, "start_date": "2026-10-30", "registry_url": "https://clinicaltrials.gov/study/NCT07873931" }, { "nct_id": "NCT07700927", "title": "Sola2 AMF Knee System Added to Surgery and Antibiotics in Adults With Knee Implant Infection", "status": "RECRUITING", "phase": "Not applicable", "lead_sponsor": "Solenic Medical, Inc.", "conditions": [ "Prosthetic Joint Infection of Knee" ], "sites": [ "New Albany", "Tulsa" ], "enrollment": 165, "start_date": "2026-10-30", "registry_url": "https://clinicaltrials.gov/study/NCT07700927" }, { "nct_id": "NCT07772531", "title": "A Study to Evaluate BMS-986511 in Adults With Major Depressive Disorder", "status": "NOT_YET_RECRUITING", "phase": "Phase 2", "lead_sponsor": "Bristol-Myers Squibb", "conditions": [ "Major Depressive Disorder" ], "sites": [ "Phoenix", "Little Rock", "Rogers", "Garden Grove", "Glendale", "Lemon Grove", "Oakland", "Upland" ], "enrollment": 200, "start_date": "2026-10-30", "registry_url": "https://clinicaltrials.gov/study/NCT07772531" }, { "nct_id": "NCT07310420", "title": "A Trial to Evaluate Ovarian Suppression Following Subcutaneous ZOLADEX 10.8 mg in Premenopausal Women With Early-stage and Advanced HR+ Breast Cancer", "status": "RECRUITING", "phase": "Phase 1", "lead_sponsor": "TerSera Therapeutics LLC", "conditions": [ "Advanced Breast Cancer", "Early Breast Cancer" ], "sites": [ "Hot Springs", "Washington D.C.", "Ocoee", "Athens", "Savannah", "Chicago", "Evanston", "Lisle" ], "enrollment": 176, "start_date": "2026-10-30", "registry_url": "https://clinicaltrials.gov/study/NCT07310420" }, { "nct_id": "NCT07864623", "title": "A Postmarketing Study of LEQEMBI in Participants With Alzheimer's Disease", "status": "NOT_YET_RECRUITING", "phase": "Observational", "lead_sponsor": "Eisai Inc.", "conditions": [ "Alzheimers Disease" ], "sites": [ "Nutley" ], "enrollment": 270, "start_date": "2026-10-30", "registry_url": "https://clinicaltrials.gov/study/NCT07864623" }, { "nct_id": "NCT07903415", "title": "A Study to Learn About the Study Medicine Called PF-08098488 in People With Advanced Solid Tumors.", "status": "RECRUITING", "phase": "Phase 1", "lead_sponsor": "Pfizer", "conditions": [ "Pancreatic Ductal Adenocarcinoma", "Esophageal Cancer", "Carcinoma, Non-Small-Cell Lung (NSCLC)", "Gastric Carcinoma" ], "sites": [ "Grand Rapids", "San Antonio" ], "enrollment": 280, "start_date": "2026-10-29", "registry_url": "https://clinicaltrials.gov/study/NCT07903415" }, { "nct_id": "NCT07873216", "title": "Radicle GI HealthTM VKP: A Study Assessing the Impact of Health and Wellness Products on Gastrointestinal-related Quality of Life and Related Health Outcomes", "status": "NOT_YET_RECRUITING", "phase": "Not applicable", "lead_sponsor": "Radicle Science", "conditions": [ "Digestion", "GI Health" ], "sites": [ "Del Mar" ], "enrollment": 330, "start_date": "2026-10-29", "registry_url": "https://clinicaltrials.gov/study/NCT07873216" }, { "nct_id": "NCT07798427", "title": "TruVascular Access - Ultrasound-Guided Vascular Access Study", "status": "ENROLLING_BY_INVITATION", "phase": "Not applicable", "lead_sponsor": "Truway Health, Inc.", "conditions": [ "Peripheral Venous Catheterization", "Difficult Intravenous Access", "Catheterization, Peripheral" ], "sites": [ "New York" ], "enrollment": 250, "start_date": "2026-10-29", "registry_url": "https://clinicaltrials.gov/study/NCT07798427" }, { "nct_id": "NCT07862647", "title": "TMZ + RT + 5-ALA + LIDU SDT System for Newly Diagnosed Butterfly Glioma", "status": "RECRUITING", "phase": "Phase 1", "lead_sponsor": "Alpheus Medical, Inc.", "conditions": [ "Glioblastom WHO Grade 4", "GBM", "bGBM", "Butterfly GBM" ], "sites": [ "Buffalo" ], "enrollment": 30, "start_date": "2026-10-29", "registry_url": "https://clinicaltrials.gov/study/NCT07862647" }, { "nct_id": "NCT07886372", "title": "Effects of Mango on Insulin Sensitivity in Prediabetes", "status": "NOT_YET_RECRUITING", "phase": "Not applicable", "lead_sponsor": "Clinical Nutrition Research Center, Illinois Institute of Technology", "conditions": [ "Pre Diabetes" ], "sites": [ "Chicago" ], "enrollment": 64, "start_date": "2026-10-28", "registry_url": "https://clinicaltrials.gov/study/NCT07886372" }, { "nct_id": "NCT07871409", "title": "Home Self-administration of Maridebart Cafraglutide With Autoinjector in Adults Living With Obesity or Overweight", "status": "NOT_YET_RECRUITING", "phase": "Phase 3", "lead_sponsor": "Amgen", "conditions": [ "Obesity", "Overweight" ], "sites": [ "The Villages" ], "enrollment": 230, "start_date": "2026-10-28", "registry_url": "https://clinicaltrials.gov/study/NCT07871409" }, { "nct_id": "NCT07707895", "title": "DAREON\u00ae-36: A Study to Test Obrixtamig in Combination With ZL-1310 in People With Advanced Small Cell Lung Cancer or Other Neuroendocrine Cancers", "status": "NOT_YET_RECRUITING", "phase": "Phase 1/2", "lead_sponsor": "Boehringer Ingelheim", "conditions": [ "Small Cell Lung Cancer", "Large Cell Neuroendocrine Lung Carcinoma", "Extrapulmonary Neuroendocrine Carcinoma of Small Cell Histology", "Extrapulmonary Neuroendocrine Carcinoma of Large Cell Histology" ], "sites": [ "Washington D.C.", "Tampa", "Lexington" ], "enrollment": 60, "start_date": "2026-10-28", "registry_url": "https://clinicaltrials.gov/study/NCT07707895" }, { "nct_id": "NCT07793942", "title": "A Clinical Trial of MK-2010 Alone and With Other Treatments in Participants With Advanced Solid Tumors (MK-2010-002)", "status": "NOT_YET_RECRUITING", "phase": "Phase 2", "lead_sponsor": "Merck Sharp & Dohme LLC", "conditions": [ "Malignant Neoplam", "Advanced Solid Tumors" ], "sites": [ "Belleville", "East Brunswick", "Maumee", "Eugene" ], "enrollment": 480, "start_date": "2026-10-27", "registry_url": "https://clinicaltrials.gov/study/NCT07793942" }, { "nct_id": "NCT06964230", "title": "A Phase 2b/3 Clinical Study Evaluating T3D-959 in Mild-to-Moderate Alzheimer's Disease Subjects", "status": "NOT_YET_RECRUITING", "phase": "Phase 2/3", "lead_sponsor": "T3D Therapeutics, Inc.", "conditions": [ "Alzheimer's Disease" ], "sites": [ "Durham" ], "enrollment": 376, "start_date": "2026-10-26", "registry_url": "https://clinicaltrials.gov/study/NCT06964230" }, { "nct_id": "NCT07851103", "title": "A Study to Test Different Doses of BI 3968621 When Given Alone or With Ezabenlimab in Patients With Advanced Cancer", "status": "RECRUITING", "phase": "Phase 1", "lead_sponsor": "Boehringer Ingelheim", "conditions": [ "Advanced Solid Tumour" ], "sites": [ "Sarasota", "Atlanta", "Philadelphia", "Nashville", "Houston" ], "enrollment": 90, "start_date": "2026-10-26", "registry_url": "https://clinicaltrials.gov/study/NCT07851103" }, { "nct_id": "NCT07778836", "title": "A Study to Evaluate the Efficacy and Safety of Subcutaneous Nomlabofusp in Subjects With Friedreich's Ataxia", "status": "RECRUITING", "phase": "Phase 3", "lead_sponsor": "Larimar Therapeutics, Inc.", "conditions": [ "Friedreich Ataxia", "Friedreich's Ataxia" ], "sites": [ "Tampa", "Chicago", "Eatontown", "Dallas" ], "enrollment": 150, "start_date": "2026-10-26", "registry_url": "https://clinicaltrials.gov/study/NCT07778836" }, { "nct_id": "NCT07861100", "title": "A Research Study to Look at How Well Zenagamtide Works Compared to Placebo in People With Established Atherosclerotic Cardiovascular Disease and Either Overweight or Obesity", "status": "NOT_YET_RECRUITING", "phase": "Phase 3", "lead_sponsor": "Novo Nordisk A/S", "conditions": [ "Cardiovascular Risk", "Obesity" ], "sites": [ "Birmingham", "Fairhope", "Mobile", "Montgomery", "Gilbert", "Glendale", "Scottsdale", "Surprise" ], "enrollment": 8500, "start_date": "2026-10-26", "registry_url": "https://clinicaltrials.gov/study/NCT07861100" }, { "nct_id": "NCT06628687", "title": "A Study to Learn How BIIB141 (Omaveloxolone) Affects the Health of Participants With Friedrich's Ataxia Who Took it During Pregnancy and/or During Breastfeeding and About the Health of Their Babies", "status": "RECRUITING", "phase": "Observational", "lead_sponsor": "Biogen", "conditions": [ "Friedreich Ataxia" ], "sites": [ "Morrisville" ], "enrollment": 10, "start_date": "2026-10-26", "registry_url": "https://clinicaltrials.gov/study/NCT06628687" }, { "nct_id": "NCT07847814", "title": "Evaluation of F&P Mask, US, 2026", "status": "NOT_YET_RECRUITING", "phase": "Not applicable", "lead_sponsor": "Fisher and Paykel Healthcare", "conditions": [ "Chronic Respiratory Conditions", "Obstructive Sleep Apnea (OSA)" ], "sites": [ "Columbia" ], "enrollment": 45, "start_date": "2026-10-26", "registry_url": "https://clinicaltrials.gov/study/NCT07847814" }, { "nct_id": "NCT07869654", "title": "A Study to Investigate the Safety, Tolerability, and Pharmacokinetics of ATI-105 in Healthy Adults", "status": "NOT_YET_RECRUITING", "phase": "Phase 1", "lead_sponsor": "Adjuvia Therapeutics, Inc.", "conditions": [ "Friedreich Ataxia", "Cardiomyopathies", "Central Nervous System Diseases", "Neuromuscular Diseases" ], "sites": [ "Miami" ], "enrollment": 60, "start_date": "2026-10-26", "registry_url": "https://clinicaltrials.gov/study/NCT07869654" }, { "nct_id": "NCT07871968", "title": "A Study to Investigate Pivmecillinam Versus Nitrofurantoin in Female Adolescents 12 to Less Than 18 Years of Age With Uncomplicated Urinary Tract Infection", "status": "NOT_YET_RECRUITING", "phase": "Phase 2", "lead_sponsor": "Alembic Therapeutics", "conditions": [ "Uncomplicated Urinary Tract Infections" ], "sites": [ "Dearborn Heights" ], "enrollment": 100, "start_date": "2026-10-24", "registry_url": "https://clinicaltrials.gov/study/NCT07871968" }, { "nct_id": "NCT07903675", "title": "Effectiveness of the Autism Pupil Screen (APS) Detect Pupillometer for Identifying Autism Spectrum Disorder (ASD) in Routine Healthcare", "status": "RECRUITING", "phase": "Observational", "lead_sponsor": "Schweitzer Engineering Laboratories", "conditions": [ "Autism Spectrum Disorder" ], "sites": [ "Lewiston", "Moscow", "Pullman" ], "enrollment": 330, "start_date": "2026-10-23", "registry_url": "https://clinicaltrials.gov/study/NCT07903675" }, { "nct_id": "NCT07663630", "title": "A Study to Learn About the Study Medicine Called Ponsegromab in Adults With Lung Cancer-Associated Significant Body Weight Loss", "status": "NOT_YET_RECRUITING", "phase": "Phase 1", "lead_sponsor": "Pfizer", "conditions": [ "Non-small Cell Lung Cancer (NSCLC)", "Cachexia" ], "sites": [ "Decatur", "O'Fallon", "Garland", "Houston" ], "enrollment": 80, "start_date": "2026-10-23", "registry_url": "https://clinicaltrials.gov/study/NCT07663630" }, { "nct_id": "NCT07788040", "title": "Intracardiac Echocardiography Catheter Supply-Chain Reliability and Clinical Access Study", "status": "ENROLLING_BY_INVITATION", "phase": "Observational", "lead_sponsor": "Truway Health, Inc.", "conditions": [ "Cardiovascular Diseases", "Arrhythmias, Cardiac", "Atrial Fibrillation" ], "sites": [ "New York" ], "enrollment": 200, "start_date": "2026-10-23", "registry_url": "https://clinicaltrials.gov/study/NCT07788040" }, { "nct_id": "NCT07904793", "title": "Care COMPASS Study", "status": "NOT_YET_RECRUITING", "phase": "Not applicable", "lead_sponsor": "Fitbit LLC", "conditions": [ "Diabetes Mellitus ( Type 1 and Type 2)", "Hypertension" ], "sites": [ "Portland" ], "enrollment": 200, "start_date": "2026-10-22", "registry_url": "https://clinicaltrials.gov/study/NCT07904793" }, { "nct_id": "NCT07908056", "title": "Evaluate Precision of the Test for Lactate in Capillary Whole Blood Specimens Using the i-STAT CG4+ Cartridge With the i-STAT 1 Analyzer", "status": "NOT_YET_RECRUITING", "phase": "Observational", "lead_sponsor": "Abbott Point of Care", "conditions": [ "Lactate" ], "sites": [ "Hackensack", "Hershey", "Milwaukee" ], "enrollment": 425, "start_date": "2026-10-22", "registry_url": "https://clinicaltrials.gov/study/NCT07908056" }, { "nct_id": "NCT07020000", "title": "The Objective of the Protocol is to Generate Real World Evidence (RWE) Supporting the Safety, Performance, and Health Economics of Using the Regulatory Approved and Commercially Available EARP Interbody System Used During Lumbar Interbody Fusion (LIF) Procedures With the EARP Nerve Cuff Electrode", "status": "RECRUITING", "phase": "Observational", "lead_sponsor": "Retropsoas Technologies, LLC", "conditions": [ "Transforaminal Lumbar Interbody Fusion Surgery" ], "sites": [ "Jacksonville", "St Louis", "Philadelphia", "Pittsburgh", "Houston" ], "enrollment": 120, "start_date": "2026-10-22", "registry_url": "https://clinicaltrials.gov/study/NCT07020000" }, { "nct_id": "NCT07764614", "title": "Tornier Perform\u2122 Reversed Monopost Study", "status": "RECRUITING", "phase": "Observational", "lead_sponsor": "Stryker Trauma and Extremities", "conditions": [ "Non-inflammatory Degenerative Joint Disease", "Rhematoid Arthritis", "Correction of Functional Deformity", "Fracture of the Humeral Head" ], "sites": [ "Rancho Mirage", "Columbus" ], "enrollment": 150, "start_date": "2026-10-22", "registry_url": "https://clinicaltrials.gov/study/NCT07764614" }, { "nct_id": "NCT07123779", "title": "HS235 Study in Overweight and Obese Participants With Combined Pre and Post-Capillary Pulmonary Hypertension Due to Heart Failure With Preserved Ejection Fraction", "status": "RECRUITING", "phase": "Phase 1/2", "lead_sponsor": "35Pharma Inc., a GSK company", "conditions": [ "Pulmonary Hypertension", "Heart Failure With Preserved Ejection Fraction" ], "sites": [ "Kansas City", "Greenville", "Dallas" ], "enrollment": 126, "start_date": "2026-10-21", "registry_url": "https://clinicaltrials.gov/study/NCT07123779" }, { "nct_id": "NCT07775495", "title": "Observational Study of Decentralized Urine Optical Interaction Patterns Associated With Environmental Microplastic and Nanoplastic Exposure", "status": "RECRUITING", "phase": "Observational", "lead_sponsor": "Ecotera Health LLC", "conditions": [ "Healthy Adult Participants" ], "sites": [ "Birmingham", "Anchorage", "Phoenix", "Little Rock", "San Francisco", "Denver", "Hartford", "Dover" ], "enrollment": 15, "start_date": "2026-10-21", "registry_url": "https://clinicaltrials.gov/study/NCT07775495" }, { "nct_id": "NCT07722611", "title": "A Clinical Trial of Bomedemstat in Participants With Polycythemia Vera (MK-3543-025).", "status": "RECRUITING", "phase": "Phase 2/3", "lead_sponsor": "Merck Sharp & Dohme LLC", "conditions": [ "Polycythemia Vera" ], "sites": [ "Charlottesville" ], "enrollment": 380, "start_date": "2026-10-21", "registry_url": "https://clinicaltrials.gov/study/NCT07722611" }, { "nct_id": "NCT07886385", "title": "Differential Absorption Kinetics of Grape Seed Extract Polyphenols", "status": "NOT_YET_RECRUITING", "phase": "Not applicable", "lead_sponsor": "Clinical Nutrition Research Center, Illinois Institute of Technology", "conditions": [ "Healthy Adults" ], "sites": [ "Chicago" ], "enrollment": 10, "start_date": "2026-10-20", "registry_url": "https://clinicaltrials.gov/study/NCT07886385" }, { "nct_id": "NCT07874880", "title": "MTX-531-001 Phase 1 Study in Advanced Solid Tumors", "status": "NOT_YET_RECRUITING", "phase": "Phase 1", "lead_sponsor": "MEKanistic Therapeutics, Inc.", "conditions": [ "Solid Tumors (Phase 1)", "HNSCC", "Endometrial Cancer", "Her2-negative Metastatic Breast Cancer" ], "sites": [ "Newport Beach" ], "enrollment": 71, "start_date": "2026-10-20", "registry_url": "https://clinicaltrials.gov/study/NCT07874880" }, { "nct_id": "NCT07881757", "title": "A Study to Learn About the Monthly Dosing Study Medicine Called Berobenatide in Adults With Breathing Problems During Sleep and Overweight or Obesity Who Do Not Use a Breathing Machine (PAP) (VESPER-OSA 2)", "status": "NOT_YET_RECRUITING", "phase": "Phase 3", "lead_sponsor": "Pfizer", "conditions": [ "Apnea", "Sleep Disorders", "Overweight and/or Obesity" ], "sites": [ "Bradenton", "Tomball" ], "enrollment": 258, "start_date": "2026-10-19", "registry_url": "https://clinicaltrials.gov/study/NCT07881757" }, { "nct_id": "NCT07807345", "title": "Phase 1 Study of STRO-006 in Adults With Refractory Solid Tumors That Are Recurrent or Metastatic", "status": "RECRUITING", "phase": "Phase 1", "lead_sponsor": "Sutro Biopharma, Inc.", "conditions": [ "Head & Neck Squamous Cell Carcinoma", "Non-Small Cell Lung Cancer", "Esophageal Cancer", "Gastric Cancer" ], "sites": [ "Orlando", "Boston", "Oklahoma City", "Irving", "Lubbock", "Fairfax" ], "enrollment": 285, "start_date": "2026-10-19", "registry_url": "https://clinicaltrials.gov/study/NCT07807345" }, { "nct_id": "NCT07877194", "title": "A Clinical Study of Ivonescimab in Combination With Cadonilimab or Ipilimumab for Advanced Renal Cancer", "status": "NOT_YET_RECRUITING", "phase": "Phase 2", "lead_sponsor": "Summit Therapeutics", "conditions": [ "Renal Cell Carcinoma, Clear Cell" ], "sites": [ "Los Angeles" ], "enrollment": 100, "start_date": "2026-10-19", "registry_url": "https://clinicaltrials.gov/study/NCT07877194" }, { "nct_id": "NCT07851038", "title": "Focused Ultrasound for Behavioral Health", "status": "RECRUITING", "phase": "Not applicable", "lead_sponsor": "Attune Neurosciences Inc", "conditions": [ "Depression", "Anxiety", "Obsessive Compulsive Disorder (OCD)" ], "sites": [ "San Francisco" ], "enrollment": 300, "start_date": "2026-10-19", "registry_url": "https://clinicaltrials.gov/study/NCT07851038" }, { "nct_id": "NCT07876531", "title": "A Study to Learn How Different Forms of the Study Medicine Called Berobenatide is Taken up Into the Blood in Adults With Overweight or Obesity", "status": "NOT_YET_RECRUITING", "phase": "Phase 1", "lead_sponsor": "Pfizer", "conditions": [ "Overweight and/or Obesity", "Healthy Participants" ], "sites": [ "Anaheim" ], "enrollment": 144, "start_date": "2026-10-16", "registry_url": "https://clinicaltrials.gov/study/NCT07876531" }, { "nct_id": "NCT07868926", "title": "Absorption, Distribution, Metabolism, and Excretion of 14C-VX-407 After a Single Oral Dose", "status": "RECRUITING", "phase": "Phase 1", "lead_sponsor": "Vertex Pharmaceuticals Incorporated", "conditions": [ "Autosomal Dominant Polycystic Kidney Disease (ADPKD)" ], "sites": [ "Lincoln" ], "enrollment": 8, "start_date": "2026-10-16", "registry_url": "https://clinicaltrials.gov/study/NCT07868926" }, { "nct_id": "NCT07830732", "title": "A Research Study Investigating Denecimig (Mim8) in Adults With Acquired Haemophilia A", "status": "RECRUITING", "phase": "Phase 3", "lead_sponsor": "Novo Nordisk A/S", "conditions": [ "Haemophilia A" ], "sites": [ "Iowa City", "Metairie", "Minneapolis", "Rochester", "St Louis", "Chapel Hill", "Durham", "Oklahoma City" ], "enrollment": 84, "start_date": "2026-10-16", "registry_url": "https://clinicaltrials.gov/study/NCT07830732" }, { "nct_id": "NCT07840287", "title": "A Long-Term Extension (LTE) Study Of Enpatoran In Cutaneous Manifestations Of Lupus With Or Without Systemic Disease [Elowen-LTE]", "status": "NOT_YET_RECRUITING", "phase": "Phase 3", "lead_sponsor": "EMD Serono Research & Development Institute, Inc.", "conditions": [ "Systemic Lupus Erythematosus (SLE)", "Cutaneous Lupus Erythematosus (CLE)" ], "sites": [ "Billerica" ], "enrollment": 404, "start_date": "2026-10-15", "registry_url": "https://clinicaltrials.gov/study/NCT07840287" }, { "nct_id": "NCT07870746", "title": "Phase 2a Study to Assess Safety and Efficacy of Two 177Lu-TLX250 Dosing Regimens in Advanced Relapsed or Recurrent ccRCC", "status": "NOT_YET_RECRUITING", "phase": "Phase 2", "lead_sponsor": "Telix Pharmaceuticals (Innovations) Pty Limited", "conditions": [ "ccRCC", "Renal Cell Carcinoma (Kidney Cancer)", "Renal Cell Carcinoma (RCC)", "Renal Cell Cancer Metastatic" ], "sites": [ "Duarte", "San Diego", "Miami", "Tampa", "Ann Arbor", "Cleveland", "Pittsburgh", "Milwaukee" ], "enrollment": 40, "start_date": "2026-10-15", "registry_url": "https://clinicaltrials.gov/study/NCT07870746" }, { "nct_id": "NCT07613359", "title": "A Study of Mezagitamab in Adults With Late Antibody-Mediated Rejection (AMR) After a Kidney Transplant", "status": "NOT_YET_RECRUITING", "phase": "Phase 2", "lead_sponsor": "Takeda", "conditions": [ "Antibody-Mediated Rejection (AMR)" ], "sites": [ "Los Angeles", "San Francisco", "Miami", "Tampa", "Baltimore", "St Louis", "Livingston", "New York" ], "enrollment": 36, "start_date": "2026-10-15", "registry_url": "https://clinicaltrials.gov/study/NCT07613359" }, { "nct_id": "NCT07828236", "title": "PHASE 1 TRIAL OF Lm-LLO-TT AND GEMCITABINE IN UNRESECTABLE PANCREATIC DUCTAL ADENOCARCINOMA", "status": "NOT_YET_RECRUITING", "phase": "Phase 1", "lead_sponsor": "Loki Therapeutics, Inc.", "conditions": [ "Pancreas Cancer, Duct Cell Adenocarcinoma", "Pancreatic Cancer", "Advanced Pancreatic Adenocarcinoma" ], "sites": [ "The Bronx" ], "enrollment": 18, "start_date": "2026-10-15", "registry_url": "https://clinicaltrials.gov/study/NCT07828236" }, { "nct_id": "NCT07859709", "title": "The CLASP III TR CED Study", "status": "NOT_YET_RECRUITING", "phase": "Observational", "lead_sponsor": "Edwards Lifesciences", "conditions": [ "Tricuspid Regurgitation", "Heart Valve Diseases", "Heart Diseases", "Cardiovascular Diseases" ], "sites": [ "Irvine" ], "enrollment": 2350, "start_date": "2026-10-15", "registry_url": "https://clinicaltrials.gov/study/NCT07859709" }, { "nct_id": "NCT07867574", "title": "AGED Diagnostics Clinical Validation Study", "status": "NOT_YET_RECRUITING", "phase": "Observational", "lead_sponsor": "Active Genomes Expressed Diagnostics, Corp", "conditions": [ "MASH - Metabolic Dysfunction-Associated Steatohepatitis", "MASLD (Metabolic Dysfunction-Associated Steatotic Liver Disease)", "Fibrosis and Cirrhosis of Liver", "MetALD" ], "sites": [ "Bethesda" ], "enrollment": 500, "start_date": "2026-10-15", "registry_url": "https://clinicaltrials.gov/study/NCT07867574" }, { "nct_id": "NCT07856082", "title": "Opt-IVF for Personalized Medicine for Normal Responders", "status": "RECRUITING", "phase": "Phase 1/2", "lead_sponsor": "Urmila DIwekar", "conditions": [ "Ivf" ], "sites": [ "West Palm Beach" ], "enrollment": 100, "start_date": "2026-10-15", "registry_url": "https://clinicaltrials.gov/study/NCT07856082" }, { "nct_id": "NCT07821697", "title": "Translational Recording and Characterization of Epilepsy Signals Using Subgaleal EEG During Standard-of-care SEEG Monitoring", "status": "NOT_YET_RECRUITING", "phase": "Early Phase 1", "lead_sponsor": "Adraxe Corp.", "conditions": [ "Epilepsy (Treatment Refractory)" ], "sites": [ "Minneapolis" ], "enrollment": 15, "start_date": "2026-10-15", "registry_url": "https://clinicaltrials.gov/study/NCT07821697" }, { "nct_id": "NCT07901608", "title": "Philips Inflationary-Based Non-Invasive Blood Pressure Validation Study", "status": "RECRUITING", "phase": "Observational", "lead_sponsor": "Philips Clinical & Medical 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"2026-10-15", "registry_url": "https://clinicaltrials.gov/study/NCT07722767" }, { "nct_id": "NCT07826637", "title": "Study of the Hemorai Vysio Wearable Device for Monitoring Changes Related to Blood Loss in Patients During and After Surgery.", "status": "NOT_YET_RECRUITING", "phase": "Not applicable", "lead_sponsor": "Hemorai Inc", "conditions": [ "Blood Loss, Surgical", "Postoperative Hemorrhage" ], "sites": [ "Burlington" ], "enrollment": 80, "start_date": "2026-10-15", "registry_url": "https://clinicaltrials.gov/study/NCT07826637" }, { "nct_id": "NCT07563803", "title": "The restor3d Outcomes Registry", "status": "RECRUITING", "phase": "Observational", "lead_sponsor": "Restor3D", "conditions": [ "Joint Replacement", "Arthropathy" ], "sites": [ "Durham" ], "enrollment": 2250, "start_date": "2026-10-15", "registry_url": "https://clinicaltrials.gov/study/NCT07563803" }, { "nct_id": "NCT07870395", "title": "Voice-based Outcome Identification and Clinical Evaluation in Heart Failure", "status": "RECRUITING", "phase": "Observational", "lead_sponsor": "Noah Labs", "conditions": [ "Heart Failure", "Chronic Heart Failure", "Chronic Heart Disease" ], "sites": [ "Boston" ], "enrollment": 450, "start_date": "2026-10-15", "registry_url": "https://clinicaltrials.gov/study/NCT07870395" }, { "nct_id": "NCT07801495", "title": "A Study to Assess the Efficacy, Safety and Tolerability of DDY391 in Participants With Moderate to Severe Psoriatic Arthritis", "status": "RECRUITING", "phase": "Phase 2", "lead_sponsor": "Novartis Pharmaceuticals", "conditions": [ "Moderate to Severe Psoriatic Arthritis" ], "sites": [ "Memphis", "Colleyville", "San Antonio" ], "enrollment": 220, "start_date": "2026-10-14", "registry_url": "https://clinicaltrials.gov/study/NCT07801495" }, { "nct_id": "NCT07460375", "title": "A Study to Evaluate Claudin 18.2-Directed ADC LCB02A in Advanced Solid Tumors", "status": "RECRUITING", "phase": "Phase 1/2", "lead_sponsor": "LigaChem Biosciences, Inc.", "conditions": [ "Advanced Solid Tumors" ], "sites": [ "Boston", "Lake Success", "Charleston", "Houston" ], "enrollment": 191, "start_date": "2026-10-14", "registry_url": "https://clinicaltrials.gov/study/NCT07460375" }, { "nct_id": "NCT07578649", "title": "Symbiotic-GYN-18: A Study to Learn About the Study Medicine Called PF-08634404 in Combination With Chemotherapy in Adult Participants With Advanced or Recurrent MMR-proficient Endometrial Cancer", "status": "RECRUITING", "phase": "Phase 3", "lead_sponsor": "Pfizer", "conditions": [ "Endometrial Neoplasms", "Endometrial Cancer" ], "sites": [ "Jupiter", "Orlando", "Coon Rapids", "Edina", "Maple Grove", "Maplewood", "Woodbury", "Reno" ], "enrollment": 600, "start_date": "2026-10-14", "registry_url": "https://clinicaltrials.gov/study/NCT07578649" }, { "nct_id": "NCT07598825", "title": "A Trial of Inebilizumab in Participants With Autoimmune Hepatitis", "status": "RECRUITING", "phase": "Phase 3", "lead_sponsor": "Amgen", "conditions": [ "Autoimmune Hepatitis", "AIH" ], "sites": [ "Little Rock", "Rialto", "Valencia", "Miami Lakes", "Indianapolis", "Dallas", "San Antonio" ], "enrollment": 180, "start_date": "2026-10-13", "registry_url": "https://clinicaltrials.gov/study/NCT07598825" }, { "nct_id": "NCT07857733", "title": "Phase 3, Open-Label Extension Study of AMBTX-01 (Neridronate) for Complex Regional Pain Syndrome Type 1", "status": "RECRUITING", "phase": "Phase 3", "lead_sponsor": "Ambros Therapeutics, Inc.", "conditions": [ "Complex Regional Pain Syndrome Type I" ], "sites": [ "Phoenix" ], "enrollment": 135, "start_date": "2026-10-13", "registry_url": "https://clinicaltrials.gov/study/NCT07857733" }, { "nct_id": "NCT07739966", "title": "A Study of DS-3939a in Participants With Solid Tumors", "status": "RECRUITING", "phase": "Phase 1/2", "lead_sponsor": "Daiichi Sankyo", "conditions": [ "Solid Tumor", "Locally Advanced Non-Small Cell Lung Cancer", "Metastatic Non-Small Cell Lung Cancer" ], "sites": [ "Fayetteville", "Los Angeles", "Tampa", "Portland", "Providence", "Houston", "Fairfax" ], "enrollment": 400, "start_date": "2026-10-13", "registry_url": "https://clinicaltrials.gov/study/NCT07739966" }, { "nct_id": "NCT07526896", "title": "Advancing Clinical Heart Failure Outcomes Leveraging Defibrillation Lead Implant System for Left Bundle Branch Area Pacing", "status": "RECRUITING", "phase": "Not applicable", "lead_sponsor": "Medtronic Cardiac Rhythm and Heart Failure", "conditions": [ "Heart Failure", "Systolic Bundle Branch Block, Left" ], "sites": [ "Minneapolis" ], "enrollment": 110, "start_date": "2026-10-13", "registry_url": "https://clinicaltrials.gov/study/NCT07526896" }, { "nct_id": "NCT07893106", "title": "A Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of ASC36 Tablets for Oral Use in Adult Participants With Obesity or Overweight", "status": "RECRUITING", "phase": "Phase 1", "lead_sponsor": "Ascletis Pharma (China) Co., Limited", "conditions": [ "Chronic Weight Management" ], "sites": [ "South Miami" ], "enrollment": 86, "start_date": "2026-10-13", "registry_url": "https://clinicaltrials.gov/study/NCT07893106" }, { "nct_id": "NCT07700758", "title": "A Study of Belzutifan in Adolescent Participants With Solid Tumors (MK-9999-01E/LIGHTBEAM-U01)", "status": "RECRUITING", "phase": "Phase 2", "lead_sponsor": "Merck Sharp & Dohme LLC", "conditions": [ "Malignant Neoplasm" ], "sites": [ "Iowa City" ], "enrollment": 15, "start_date": "2026-10-13", "registry_url": "https://clinicaltrials.gov/study/NCT07700758" }, { "nct_id": "NCT07871435", "title": "GI-102 (CD80-IgG4 Fc-IL2v3) in Combination With Pasritamig in Patients With Metastatic Castration-resistant Prostate Cancer (mCRPC) (JET-201)", "status": "RECRUITING", "phase": "Phase 1/2", "lead_sponsor": "GI Innovation, Inc.", "conditions": [ "Metastatic Castration-resistant Prostate Cancer (mCRPC)" ], "sites": [ "New York" ], "enrollment": 107, "start_date": "2026-10-12", "registry_url": "https://clinicaltrials.gov/study/NCT07871435" }, { "nct_id": "NCT07873957", "title": "IgG Binding Protein LT in Support of a Healthy Gut on the Go", "status": "RECRUITING", "phase": "Not applicable", "lead_sponsor": "Bactolife A/S", "conditions": [ "Gut Health", "Gastrointestinal Symptoms", "Safety in Healthy Adults" ], "sites": [ "Los Angeles" ], "enrollment": 800, "start_date": "2026-10-12", "registry_url": "https://clinicaltrials.gov/study/NCT07873957" }, { "nct_id": "NCT07906262", "title": "Efficacy of Rimegepant 75 mg for the Acute Treatment of Migraine: a Bayesian Individual Participant Data Meta-analysis Standardized to Defined Target Populations", "status": "ACTIVE_NOT_RECRUITING", "phase": "Observational", "lead_sponsor": "Pfizer", "conditions": [ "Migraine" ], "sites": [ "New York" ], "enrollment": 1, "start_date": "2026-10-12", "registry_url": "https://clinicaltrials.gov/study/NCT07906262" }, { "nct_id": "NCT07846631", "title": "Perioperative Photobiomodulation in Facial Plastic Surgery", "status": "NOT_YET_RECRUITING", "phase": "Not applicable", "lead_sponsor": "Elixir MD Inc", "conditions": [ "Postoperative Facial Ecchymosis", "Postoperative Facial Edema" ], "sites": [ "Dallas" ], "enrollment": 40, "start_date": "2026-10-12", "registry_url": "https://clinicaltrials.gov/study/NCT07846631" }, { "nct_id": "NCT07824011", "title": "Safety and Tolerability Evaluation of IgG Binding Protein LT", "status": "RECRUITING", "phase": "Not applicable", "lead_sponsor": "Bactolife A/S", "conditions": [ "Safety and Tolerability in Healthy Volunteers" ], "sites": [ "Los Angeles" ], "enrollment": 40, "start_date": "2026-10-12", "registry_url": "https://clinicaltrials.gov/study/NCT07824011" }, { "nct_id": "NCT07873242", "title": "A Study to Evaluate the Analgesic Properties of Topically Applied Menthol in Marathon Participants", "status": "NOT_YET_RECRUITING", "phase": "Observational", "lead_sponsor": "Reckitt Benckiser Healthcare (UK) Limited", "conditions": [ "Muscle Soreness" ], "sites": [ "Deerfield" ], "enrollment": 600, "start_date": "2026-10-11", "registry_url": "https://clinicaltrials.gov/study/NCT07873242" }, { "nct_id": "NCT07884760", "title": "A Fifth Proof-of-Concept Study to Evaluate the Efficacy of NOBO, a Novel Postbiotic, in Controlling Axillary Odor in Healthy Adults", "status": "ACTIVE_NOT_RECRUITING", "phase": "Not applicable", "lead_sponsor": "Kingdom", "conditions": [ "Body Odor" ], "sites": [ "Brooklyn" ], "enrollment": 16, "start_date": "2026-10-11", "registry_url": "https://clinicaltrials.gov/study/NCT07884760" }, { "nct_id": "NCT07152379", "title": "Challenge Transfusion of INTERCEPT Pathogen Reduced Red Blood Cells (RBCs) in Subjects With or Without Pre-existing Antibodies to INTERCEPT RBCs", "status": "NOT_YET_RECRUITING", "phase": "Phase 2", "lead_sponsor": "Cerus Corporation", "conditions": [ "Transfusion Reaction, Hemolytic" ], "sites": [ "Aurora" ], "enrollment": 25, "start_date": "2026-10-10", "registry_url": "https://clinicaltrials.gov/study/NCT07152379" }, { "nct_id": "NCT07651852", "title": "Globe Registry: Globe\u00ae Pulsed Field System Registry Study for Treating Patients With Symptomatic Atrial Fibrillation", "status": "RECRUITING", "phase": "Observational", "lead_sponsor": "Kardium Inc.", "conditions": [ "Atrial Fibrillation" ], "sites": [ "Jonesboro", "Bellevue" ], "enrollment": 500, "start_date": "2026-10-09", "registry_url": "https://clinicaltrials.gov/study/NCT07651852" }, { "nct_id": "NCT07891728", "title": "A Multicenter Evaluation of SalivIQ\u2122 Strep A for Detecting Group A Streptococcus From Saliva and Throat Swabs in Patients With Acute Pharyngitis", "status": "NOT_YET_RECRUITING", "phase": "Observational", "lead_sponsor": "SalivIQ Diagnostics, Inc.", "conditions": [ "Streptococcal Pharyngitis", "Group A Streptococcal Infection" ], "sites": [ "Baton Rouge", "North Andover", "Dallas" ], "enrollment": 668, "start_date": "2026-10-09", "registry_url": "https://clinicaltrials.gov/study/NCT07891728" }, { "nct_id": "NCT07863635", "title": "A Study to Investigate the Immunogenicity and Safety of mRNA COVID-19 Variant-containing Formulations", "status": "RECRUITING", "phase": "Phase 4", "lead_sponsor": "ModernaTX, Inc.", "conditions": [ "SARS-CoV-2" ], "sites": [ "Overland Park", "Louisville", "Charlotte", "Hendersonville", "Prosper" ], "enrollment": 300, "start_date": "2026-10-09", "registry_url": "https://clinicaltrials.gov/study/NCT07863635" }, { "nct_id": "NCT07732413", "title": "Trial of NLG802 Indoximod Prodrug Plus Temozolomide for Patients With Progressive Pediatric Brain Cancer", "status": "NOT_YET_RECRUITING", "phase": "Phase 1", "lead_sponsor": "Lumos Pharma", "conditions": [ "Progressive Pediatric Brain Cancer" ], "sites": [ "Augusta" ], "enrollment": 30, "start_date": "2026-10-08", "registry_url": "https://clinicaltrials.gov/study/NCT07732413" }, { "nct_id": "NCT07835776", "title": "Radicle GI Health\u2122 RFY: A Study Assessing the Impact of DAO Supplementation on Gastrointestinal and Other Histamine Intolerance Symptoms", "status": "NOT_YET_RECRUITING", "phase": "Not applicable", "lead_sponsor": "Radicle Science", "conditions": [ "GI Health" ], "sites": [ "Del Mar" ], "enrollment": 550, "start_date": "2026-10-08", "registry_url": "https://clinicaltrials.gov/study/NCT07835776" }, { "nct_id": "NCT07846371", "title": "Effect of a Dietary Supplement Versus Placebo on Serum PFAS Levels in Male Firefighters", "status": "RECRUITING", "phase": "Not applicable", "lead_sponsor": "Cambiotics ApS", "conditions": [ "Environmental Exposure", "PFAS Exposure" ], "sites": [ "Chicago" ], "enrollment": 70, "start_date": "2026-10-08", "registry_url": "https://clinicaltrials.gov/study/NCT07846371" }, { "nct_id": "NCT07868354", "title": "A Research Study Investigating How Adults With Overweight or Obesity, With or Without Type 2 Diabetes, Tolerate Switching to a New Treatment (Zenagamtide) From Their Current Tirzepatide Medication", "status": "RECRUITING", "phase": "Phase 1", "lead_sponsor": "Novo Nordisk A/S", "conditions": [ "Overweight", "Obesity", "Type 2 Diabetes" ], "sites": [ "Glendale", "Baltimore" ], "enrollment": 60, "start_date": "2026-10-08", "registry_url": "https://clinicaltrials.gov/study/NCT07868354" }, { "nct_id": "NCT07901062", "title": "Clinical Study to Evaluate the Impact of Nutraceutical Supplements in Participants With Self-Perceived Thinning Hair", "status": "NOT_YET_RECRUITING", "phase": "Not applicable", "lead_sponsor": "Unilever R&D", "conditions": [ "Hair Thinning" ], "sites": [ "Minneapolis" ], "enrollment": 50, "start_date": "2026-10-08", "registry_url": "https://clinicaltrials.gov/study/NCT07901062" }, { "nct_id": "NCT07786454", "title": "A Trial of the Safety and Tolerability of SEP-363856 in Adults With Generalized Anxiety Disorder", "status": "RECRUITING", "phase": "Phase 3", "lead_sponsor": "Otsuka Pharmaceutical Development & Commercialization, Inc.", "conditions": [ "Generalized Anxiety Disorder" ], "sites": [ "Jacksonville", "Jamaica" ], "enrollment": 1120, "start_date": "2026-10-08", "registry_url": "https://clinicaltrials.gov/study/NCT07786454" }, { "nct_id": "NCT07852338", "title": "a Prospective, Multicenter, Randomized Controlled Trial, With a Non-randomized Sentinel Cohort, Evaluating the Efficacy of Bioxheal, a Single-layer Placental-derived Biologic in Nonhealing Diabetic Foot Ulcers", "status": "RECRUITING", "phase": "Phase 3", "lead_sponsor": "Applied Biologics, LLC", "conditions": [ "Diabetic Foot Ulcer", "Amniotic Membrane Placental Allograft", "Biologic" ], "sites": [ "Boardman" ], "enrollment": 253, "start_date": "2026-10-08", "registry_url": "https://clinicaltrials.gov/study/NCT07852338" }, { "nct_id": "NCT07822399", "title": "A Study of MGC030 in Participants With Advanced Solid Tumors", "status": "RECRUITING", "phase": "Phase 1", "lead_sponsor": "MacroGenics", "conditions": [ "Urothelial Cancer", "GastroEsophageal Cancer", "Colorectal Cancer", "Esophageal Cancer" ], "sites": [ "Lake Success" ], "enrollment": 314, "start_date": "2026-10-07", "registry_url": "https://clinicaltrials.gov/study/NCT07822399" }, { "nct_id": "NCT07870330", "title": "A Study to Evaluate the Safety, Reactogenicity, and Immunogenicity of mRNA-1010 in Healthy Children", "status": "RECRUITING", "phase": "Phase 1", "lead_sponsor": "ModernaTX, Inc.", "conditions": [ "Seasonal Influenza" ], "sites": [ "Modesto", "Aurora", "Minneapolis", "South Euclid", "Houston", "Richmond" ], "enrollment": 96, "start_date": "2026-10-07", "registry_url": "https://clinicaltrials.gov/study/NCT07870330" }, { "nct_id": "NCT07848191", "title": "Rezdiffra\u00ae With Concomitant Therapies Commonly Used to Treat Comorbidities in Adults With MASH and F2-F3 Fibrosis", "status": "RECRUITING", "phase": "Phase 4", "lead_sponsor": "Madrigal Pharmaceuticals, Inc.", "conditions": [ "MASH - Metabolic Dysfunction-Associated Steatohepatitis" ], "sites": [ "Chandler", "North Little Rock", "Coronado", "Rialto", "Lakewood Rch", "Miami", "Lake Charles", "Morehead City" ], "enrollment": 150, "start_date": "2026-10-07", "registry_url": "https://clinicaltrials.gov/study/NCT07848191" }, { "nct_id": "NCT07811869", "title": "A Study to Evaluate Efficacy, Safety, and Tolerability of Remibrutinib in Adult Participants With Severe Chronic Pruritus of Unknown Origin (CPUO)", "status": "RECRUITING", "phase": "Phase 3", "lead_sponsor": "Novartis Pharmaceuticals", "conditions": [ "Chronic Pruritus of Unknown Origin" ], "sites": [ "Tampa", "Sandy Springs", "Brighton", "Clarkston", "Mayfield Heights", "Grapevine", "San Antonio", "Sugarland" ], "enrollment": 180, "start_date": "2026-10-07", "registry_url": "https://clinicaltrials.gov/study/NCT07811869" }, { "nct_id": "NCT07785609", "title": "A Clinical Trial of MK-2010 With Sacituzumab Tirumotecan (Sac-TMT) in Participants With Solid Tumors (MK-2010)", "status": "RECRUITING", "phase": "Phase 2", "lead_sponsor": "Merck Sharp & Dohme LLC", "conditions": [ "Advanced Solid Tumors", "Malignant Neoplasm" ], "sites": [ "San Antonio" ], "enrollment": 200, "start_date": "2026-10-07", "registry_url": "https://clinicaltrials.gov/study/NCT07785609" }, { "nct_id": "NCT07855211", "title": "A Study to Learn About the Safety of BIIB147 and Its Effects in Adults With Amyotrophic Lateral Sclerosis (ALS)", "status": "RECRUITING", "phase": "Phase 1/2", "lead_sponsor": "Biogen", "conditions": [ "Amyotrophic Lateral Sclerosis" ], "sites": [ "St Louis", "Austin" ], "enrollment": 69, "start_date": "2026-10-07", "registry_url": "https://clinicaltrials.gov/study/NCT07855211" }, { "nct_id": "NCT07775287", "title": "Study of Petosemtamab Plus Chemotherapy Versus Cetuximab or Bevacizumab Plus Chemotherapy in RAS and BRAF Wild Type, Recurrent, Unresectable or Metastatic Colorectal Cancer (LiGeR-CRC2)", "status": "RECRUITING", "phase": "Phase 3", "lead_sponsor": "Genmab", "conditions": [ "Colorectal Cancer" ], "sites": [ "Los Angeles", "Savannah", "Olympia" ], "enrollment": 600, "start_date": "2026-10-07", "registry_url": "https://clinicaltrials.gov/study/NCT07775287" }, { "nct_id": "NCT07770685", "title": "A Study About the Safety of ASP2767 and Whether it Helps People With Glaucoma-Related Optic Nerve Damage", "status": "RECRUITING", "phase": "Phase 1/2", "lead_sponsor": "Astellas Pharma Global Development, Inc.", "conditions": [ "Glaucoma" ], "sites": [ "Boston" ], "enrollment": 156, "start_date": "2026-10-07", "registry_url": "https://clinicaltrials.gov/study/NCT07770685" }, { "nct_id": "NCT07871513", "title": "A Study to Assess the Safety and Efficacy of Co-Reconstituted TrenibotulinumtoxinE and OnabotulinumtoxinA in Adult Participants With Moderate to Severe Upper Facial Lines", "status": "RECRUITING", "phase": "Phase 2", "lead_sponsor": "AbbVie", "conditions": [ "Upper Facial Lines", "Glabellar Lines" ], "sites": [ "Glendale" ], "enrollment": 300, "start_date": "2026-10-07", "registry_url": "https://clinicaltrials.gov/study/NCT07871513" }, { "nct_id": "NCT07895381", "title": "A Study to Describe Patient REal-world FitusiRan ExpeRience", "status": "NOT_YET_RECRUITING", "phase": "Observational", "lead_sponsor": "Sanofi", "conditions": [ "Hemophilia A or B" ], "sites": [ "Indianapolis" ], "enrollment": 100, "start_date": "2026-10-07", "registry_url": "https://clinicaltrials.gov/study/NCT07895381" }, { "nct_id": "NCT07743164", "title": "A Clinical Trial of Raludotatug Deruxtecan (R-DXd) With or Without Bevacizumab in Participants With Ovarian Cancer Who Have Progressed During Treatment With PARP-inhibitors Treatment on First Line Maintenance (MK-5909-008/ENGOT-ov107/GOG-3142 / REJOICE-Ovarian05)", "status": "RECRUITING", "phase": "Phase 3", "lead_sponsor": "Merck Sharp & Dohme LLC", "conditions": [ "Ovarian Cancer", "Peritoneal Cancer", "Fallopian Tube Cancer" ], "sites": [ "Fountain Valley", "Orlando", "Fort Worth" ], "enrollment": 646, "start_date": "2026-10-07", "registry_url": "https://clinicaltrials.gov/study/NCT07743164" }, { "nct_id": "NCT07587658", "title": "This After Market Study is Seeing if Dupilumab Plus Usual Standard of Care (SOC) is Better Than Usual Care Alone for Adult Participants After a Severe Chronic Obstructive Pulmonary Disease (COPD) Flare-Up Requiring Hospitalization", "status": "RECRUITING", "phase": "Phase 4", "lead_sponsor": "Regeneron Pharmaceuticals", "conditions": [ "Chronic Obstructive Pulmonary Disease (COPD)" ], "sites": [ "Mullica Hill" ], "enrollment": 754, "start_date": "2026-10-06", "registry_url": "https://clinicaltrials.gov/study/NCT07587658" }, { "nct_id": "NCT07412704", "title": "A Study of BMS-986528 in Participants With Refractory Rheumatoid Arthritis", "status": "RECRUITING", "phase": "Phase 1/2", "lead_sponsor": "Bristol-Myers Squibb", "conditions": [ "Arthritis, Rheumatoid" ], "sites": [ "La Jolla", "Loma Linda", "Palo Alto", "Aurora", "Denver", "South Miami", "New York", "Portland" ], "enrollment": 84, "start_date": "2026-10-06", "registry_url": "https://clinicaltrials.gov/study/NCT07412704" }, { "nct_id": "NCT07541170", "title": "A Study to Evaluate the Efficacy and Safety of Divarasib Compared With Investigator's Choice of Immunotherapy or Observation in Participants With Resected Stage II-III KRAS G12C-Positive Non-Small Cell Lung Cancer (NSCLC)", "status": "RECRUITING", "phase": "Phase 3", "lead_sponsor": "Hoffmann-La Roche", "conditions": [ "Non-small Cell Lung Cancer" ], "sites": [ "Clovis", "Atlanta", "Farmington Hills", "Reno", "Farmington" ], "enrollment": 400, "start_date": "2026-10-06", "registry_url": "https://clinicaltrials.gov/study/NCT07541170" }, { "nct_id": "NCT07416552", "title": "A Study to Investigate CEA-PRIT 2.0 in Participants With Metastatic Colorectal Cancer (mCRC)", "status": "RECRUITING", "phase": "Phase 1", "lead_sponsor": "Hoffmann-La Roche", "conditions": [ "Metastatic Colorectal Cancer" ], "sites": [ "Chicago", "St Louis", "Omaha", "Houston", "Madison" ], "enrollment": 180, "start_date": "2026-10-06", "registry_url": "https://clinicaltrials.gov/study/NCT07416552" }, { "nct_id": "NCT07837115", "title": "A Study to Assess the Relative Bioavailability of Irafamdastat (BMS-986368) and to Assess the Food Effect on the Pharmacokinetics of Irafamdastat in Healthy Adult Participants", "status": "NOT_YET_RECRUITING", "phase": "Phase 1", "lead_sponsor": "Celgene", "conditions": [ "Healthy Volunteers" ], "sites": [ "Anaheim" ], "enrollment": 24, "start_date": "2026-10-06", "registry_url": "https://clinicaltrials.gov/study/NCT07837115" }, { "nct_id": "NCT07503561", "title": "A Trial to Evaluate the Safety, Tolerability and Efficacy of AIC263029 in Kidney Transplant Recipients With BKV Infection", "status": "RECRUITING", "phase": "Phase 2", "lead_sponsor": "AiCuris Anti-infective Cures AG", "conditions": [ "BK Virus Infection", "BKV Infection", "Kidney Transplant" ], "sites": [ "Birmingham", "Tampa", "Atlanta", "Baltimore", "Livingston", "Winston-Salem", "Cleveland" ], "enrollment": 24, "start_date": "2026-10-05", "registry_url": "https://clinicaltrials.gov/study/NCT07503561" }, { "nct_id": "NCT07864168", "title": "Evaluation of MiniMed Next Generation Extended Wear Sensors and Algorithm in Patients With Type 1 and Type 2 Diabetes", "status": "RECRUITING", "phase": "Not applicable", "lead_sponsor": "Medtronic MiniMed, Inc.", "conditions": [ "Type 1 Diabetes", "Type 2 Diabetes" ], "sites": [ "Chula Vista", "Palo Alto", "San Diego", "San Francisco", "Santa Barbara", "Walnut Creek", "Aurora", "New Haven" ], "enrollment": 1500, "start_date": "2026-10-05", "registry_url": "https://clinicaltrials.gov/study/NCT07864168" }, { "nct_id": "NCT07764809", "title": "Driving Time and Facial Skin Hydration Asymmetry in Florida Drivers", "status": "RECRUITING", "phase": "Observational", "lead_sponsor": "IAS Skin Care", "conditions": [ "Skin Diseases", "Photoaging", "Skin Hydration" ], "sites": [ "Orlando" ], "enrollment": 80, "start_date": "2026-10-05", "registry_url": "https://clinicaltrials.gov/study/NCT07764809" }, { "nct_id": "NCT07823205", "title": "A Study to Evaluate Different Oral Formulations of KT-621", "status": "RECRUITING", "phase": "Phase 1", "lead_sponsor": "Kymera Therapeutics, Inc.", "conditions": [ "Healthy Participants" ], "sites": [ "Lincoln" ], "enrollment": 54, "start_date": "2026-10-05", "registry_url": "https://clinicaltrials.gov/study/NCT07823205" }, { "nct_id": "NCT07145333", "title": "Pharmacogenomics ANDA SNP Clinical Study - Topotecan and Single Nucleotide Polymorphisms", "status": "ACTIVE_NOT_RECRUITING", "phase": "Phase 2/3", "lead_sponsor": "Han Xu, M.D., Ph.D., FAPCR, Medical Director, IRB Chair", "conditions": [ "SCLC" ], "sites": [ "Rockville" ], "enrollment": 600, "start_date": "2026-10-05", "registry_url": "https://clinicaltrials.gov/study/NCT07145333" }, { "nct_id": "NCT03655782", "title": "Retraining Neural Pathways Improves Cognitive Skills After A Mild Traumatic 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"ACTIVE_NOT_RECRUITING", "phase": "Early Phase 1", "lead_sponsor": "Han Xu, M.D., Ph.D., FAPCR, Medical Director, IRB Chair", "conditions": [ "HIV Infections" ], "sites": [ "Rockville" ], "enrollment": 20, "start_date": "2026-10-05", "registry_url": "https://clinicaltrials.gov/study/NCT07182838" }, { "nct_id": "NCT07901296", "title": "Moni-Patch Temperature Data Collection for Algorithm Development During Surgery", "status": "RECRUITING", "phase": "Not applicable", "lead_sponsor": "Murata Vios, Inc.", "conditions": [ "Body Temperature Monitoring" ], "sites": [ "Minneapolis" ], "enrollment": 30, "start_date": "2026-10-03", "registry_url": "https://clinicaltrials.gov/study/NCT07901296" }, { "nct_id": "NCT07856706", "title": "A Single Ascending Dose, and Food Effect Study of ABBV-7828 in Healthy Adults", "status": "RECRUITING", "phase": "Phase 1", "lead_sponsor": "AbbVie", "conditions": [ "Healthy Subjects" ], "sites": [ "Grayslake" ], "enrollment": 60, "start_date": "2026-10-02", "registry_url": "https://clinicaltrials.gov/study/NCT07856706" }, { "nct_id": "NCT06965504", "title": "INitiation and Titration of Guideline Directed Medical TheRApy in HearT Failure Cardiogenic Shock With ImpElla 5.5 for Cardiac Recovery", "status": "RECRUITING", "phase": "Not applicable", "lead_sponsor": "Abiomed Inc.", "conditions": [ "Heart Failure", "Cardiogenic Shock", "Reduced Ejection Fraction Heart Failure" ], "sites": [ "Tampa", "Indianapolis", "Minneapolis", "St Louis", "Hackensack", "New Brunswick", "New York", "Valhalla" ], "enrollment": 250, "start_date": "2026-10-02", "registry_url": "https://clinicaltrials.gov/study/NCT06965504" }, { "nct_id": "NCT07816367", "title": "A Study to Assess the Efficacy and Safety of Elismetrep (K-304) in the Acute Treatment of Migraine", "status": "RECRUITING", "phase": "Phase 3", "lead_sponsor": "TriGemX Bio, Inc.", "conditions": [ "Migraine" ], "sites": [ "Glendale", "Phoenix", "Little Rock", "Canoga Park", "Chula Vista", "Fountain 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"Phoenix", "Glendale", "Los Angeles", "Orange", "San Diego", "San Juan Capistrano", "San Rafael", "New Haven" ], "enrollment": 176, "start_date": "2026-10-02", "registry_url": "https://clinicaltrials.gov/study/NCT07285798" }, { "nct_id": "NCT07841990", "title": "Substudy-01: A Study of Long-Acting HIV-1 Treatments Taken by Mouth in People With HIV-1 With Undetectable Virus Levels", "status": "RECRUITING", "phase": "Phase 2", "lead_sponsor": "Gilead Sciences", "conditions": [ "HIV-1 Infection" ], "sites": [ "Ft. Pierce", "Houston" ], "enrollment": 125, "start_date": "2026-10-01", "registry_url": "https://clinicaltrials.gov/study/NCT07841990" }, { "nct_id": "NCT06606561", "title": "NANOVAE to Treat Knee Osteoarthritis (KOA)", "status": "NOT_YET_RECRUITING", "phase": "Phase 1/2", "lead_sponsor": "Nova Vita Laboratory", "conditions": [ "Knee Osteoarthritis" ], "sites": [ "Chesterfield" ], "enrollment": 24, "start_date": "2026-10-01", "registry_url": "https://clinicaltrials.gov/study/NCT06606561" }, { "nct_id": "NCT07631078", "title": "kTMP-Enhanced Motor Rehabilitation for Chronic Stroke Recovery (KULMINATE) Pilot", "status": "RECRUITING", "phase": "Not applicable", "lead_sponsor": "Magnetic Tides", "conditions": [ "Stroke", "Chronic Stroke Patients", "Arm Weakness as a Consequence of Stroke" ], "sites": [ "San Francisco" ], "enrollment": 6, "start_date": "2026-10-01", "registry_url": "https://clinicaltrials.gov/study/NCT07631078" }, { "nct_id": "NCT07587073", "title": "Comprehensive Enhanced Care Management Under CalAIM for High-Risk Medi-Cal Members", "status": "NOT_YET_RECRUITING", "phase": "Not applicable", "lead_sponsor": "StratiHealth", "conditions": [ "Complex Care", "Post-Acute Care Utilization", "Housing Instability", "Residential Care Transition" ], "sites": [ "Los Angeles" ], "enrollment": 1200, "start_date": "2026-10-01", "registry_url": "https://clinicaltrials.gov/study/NCT07587073" }, { "nct_id": "NCT07697989", "title": "Pluvicto Real-world Investigation in Survival in Metastatic CRPC", "status": "RECRUITING", "phase": "Observational", "lead_sponsor": "Novartis Pharmaceuticals", "conditions": [ "Prostatic Neoplasms, Castration-Resistant", "Neoplasm Metastasis" ], "sites": [ "East Hanover" ], "enrollment": 1085, "start_date": "2026-10-01", "registry_url": "https://clinicaltrials.gov/study/NCT07697989" }, { "nct_id": "NCT07843940", "title": "A Study to Test Obrixtamig in Combination With Pumitamig in People With Advanced Small Cell Lung Cancer (Dareon\u00ae-Rosetta35)", "status": "RECRUITING", "phase": "Phase 1/2", "lead_sponsor": "Boehringer Ingelheim", "conditions": [ "Extensive-stage Small Cell Lung Carcinoma", "Advanced Small Cell Lung Cancer" ], "sites": [ "Miami", "Boston", "East Brunswick", "New York", "Nashville" ], "enrollment": 55, "start_date": "2026-10-01", "registry_url": "https://clinicaltrials.gov/study/NCT07843940" }, { "nct_id": "NCT07861542", "title": "Study of a Recombinant Spike COVID-19 Vaccine With Matrix-M in Older Adults and People at Increased Risk of Severe COVID-19", "status": "RECRUITING", "phase": "Phase 4", "lead_sponsor": "Sanofi", "conditions": [ "COVID-19" ], "sites": [ "Fair Oaks", "Doral", "Atlanta", "Decatur", "Melrose Park", "Sioux City", "Lenexa", "Lafayette" ], "enrollment": 660, "start_date": "2026-10-01", "registry_url": "https://clinicaltrials.gov/study/NCT07861542" }, { "nct_id": "NCT06728800", "title": "Leveraging Interactive Digital Technology to Increase Access to Family-Based Behavioral Treatment for Childhood Obesity", "status": "NOT_YET_RECRUITING", "phase": "Not applicable", "lead_sponsor": "3-C Institute for Social Development", "conditions": [ "Childhood Obesity" ], "sites": [ "Durham" ], "enrollment": 66, "start_date": "2026-10-01", "registry_url": "https://clinicaltrials.gov/study/NCT06728800" }, { "nct_id": "NCT07898124", "title": "TMV Vaccine Alone or With Toripalimab-tpzi for Recurrent Head and Neck Squamous Cell Carcinoma", "status": "RECRUITING", "phase": "Phase 1", "lead_sponsor": "Metaclipse Therapeutics Corporation", "conditions": [ "Squamous Cell Carcinoma of Head and Neck", "Squamous Cell Carcinoma of Head and Neck (SCCHN)", "HNSCC", "Neoplasm Recurrence, Local" ], "sites": [ "Houston" ], "enrollment": 30, "start_date": "2026-10-01", "registry_url": "https://clinicaltrials.gov/study/NCT07898124" }, { "nct_id": "NCT07871890", "title": "A Study to Investigate Small Mobile Stem Cells (SMS) in Moderate to Severe Chronic Obstructive Pulmonary Disease", "status": "NOT_YET_RECRUITING", "phase": "Phase 1/2", "lead_sponsor": "SMSbiotech", "conditions": [ "Chronic Obstructive Lung Disease" ], "sites": [ "Miami" ], "enrollment": 125, "start_date": "2026-10-01", "registry_url": "https://clinicaltrials.gov/study/NCT07871890" }, { "nct_id": "NCT07851220", "title": "A Phase 3 Study of Inebilizumab in Participants With Primary Membranous Nephropathy", "status": "RECRUITING", "phase": "Phase 3", "lead_sponsor": "Amgen", "conditions": [ "Glomerulonephritis, Membranous" ], "sites": [ "Los Angeles", "Doral", "Miami", "Pembroke Pines" ], "enrollment": 159, "start_date": "2026-10-01", "registry_url": "https://clinicaltrials.gov/study/NCT07851220" }, { "nct_id": "NCT07529756", "title": "The ReCAna for Lower ExtremIty Venous OBstructions and In-StEnt Restenosis Registry", "status": "NOT_YET_RECRUITING", "phase": "Observational", "lead_sponsor": "Intervene, Inc.", "conditions": [ "Chronic Venous Disease", "Chronic Venous Insufficiency, CVI", "Venous Thrombosis", "Thrombosis (Stent Thrombosis)" ], "sites": [ "Oklahoma City" ], "enrollment": 500, "start_date": "2026-10-01", "registry_url": "https://clinicaltrials.gov/study/NCT07529756" }, { "nct_id": "NCT07793981", "title": "Clinical Evaluation of an Alarm Activated Detection System to Enable Early Intervention of Emerging Respiratory Decline With the Linshom Medical Continuous Predictive Respiratory Sensor (CPRS)", "status": "NOT_YET_RECRUITING", "phase": "Not applicable", "lead_sponsor": "Linshom Medical, Inc.", "conditions": [ "Post Surgical Respiratory Failure", "Respiratory Complication", "Opioid Induced Respiratory Depression", "Respiratory Arrest" ], "sites": [ "Baltimore", "Columbus" ], "enrollment": 394, "start_date": "2026-10-01", "registry_url": "https://clinicaltrials.gov/study/NCT07793981" }, { "nct_id": "NCT07300930", "title": "A Mobile Text Approach to Measurement and Feedback for Wraparound Care Coordination", "status": "NOT_YET_RECRUITING", "phase": "Not applicable", "lead_sponsor": "3-C Institute for Social Development", "conditions": [ "Mental Health Services", "Mobile Technologies", "Technology Development" ], "sites": [ "Durham" ], "enrollment": 216, "start_date": "2026-10-01", "registry_url": "https://clinicaltrials.gov/study/NCT07300930" }, { "nct_id": "NCT07873450", "title": "SumMET: Study of [225Ac]Ac-FL-261 in Participants With Solid Tumors Overexpressing c-MET", "status": "RECRUITING", "phase": "Phase 1/2", "lead_sponsor": "Full-Life Technologies UK Limited", "conditions": [ "Solid Tumor", "NSCLC", "Colorectal Cancer", "Head and Neck Cancer" ], "sites": [ "Minneapolis" ], "enrollment": 208, "start_date": "2026-10-01", "registry_url": "https://clinicaltrials.gov/study/NCT07873450" }, { "nct_id": "NCT07841977", "title": "Study of Seladelpar and Cilofexor in Participants With Primary Biliary Cholangitis", "status": "RECRUITING", "phase": "Phase 2", "lead_sponsor": "Gilead Sciences", "conditions": [ "Primary Biliary Cholangitis" ], "sites": [ "Colorado Springs", "Lakewood Rch", "Atlanta", "Johnson City" ], "enrollment": 132, "start_date": "2026-10-01", "registry_url": "https://clinicaltrials.gov/study/NCT07841977" }, { "nct_id": "NCT07851246", "title": "A Study to Evaluate the Immune Response and Safety of a Vaccine Against Influenza in Adults 18-64 Years of Age", "status": "RECRUITING", "phase": "Phase 3", "lead_sponsor": "GlaxoSmithKline", "conditions": [ "Influenza, Human" ], "sites": [ "Glendale", "Tucson", "San Diego", "Miami", "Miami Lakes", "Meridian", "Valparaiso", "Lenexa" ], "enrollment": 3000, "start_date": "2026-10-01", "registry_url": "https://clinicaltrials.gov/study/NCT07851246" }, { "nct_id": "NCT07473843", "title": "Study of Zodasiran in Adolescent Participants With Homozygous Familial Hypercholesterolemia", "status": "RECRUITING", "phase": "Phase 3", "lead_sponsor": "Arrowhead Pharmaceuticals", "conditions": [ "Homozygous Familial Hypercholesterolemia" ], "sites": [ "St Louis" ], "enrollment": 10, "start_date": "2026-10", "registry_url": "https://clinicaltrials.gov/study/NCT07473843" }, { "nct_id": "NCT07813130", "title": "A Phase 1b Study to Assess the Safety and Tolerability of AB126 Neural Exosomes in Patients With Moderate to Severe Acute Ischemic Stroke", "status": "NOT_YET_RECRUITING", "phase": "Phase 1", "lead_sponsor": "Aruna Bio, Inc.", "conditions": [ "Acute Ischemic Stroke" ], "sites": [ "Houston" ], "enrollment": 20, "start_date": "2026-10", "registry_url": "https://clinicaltrials.gov/study/NCT07813130" }, { "nct_id": "NCT07225140", "title": "A Study of Combogesic\u00ae 325 in Adolescent Patients With Moderate to Severe Postoperative Pain Associated With Orthopedic Surgery", "status": "NOT_YET_RECRUITING", "phase": "Phase 3", "lead_sponsor": "AFT Pharmaceuticals, Ltd.", "conditions": [ "Post Operative Pain, Acute" ], "sites": [ "Orlando" ], "enrollment": 180, "start_date": "2026-10", "registry_url": "https://clinicaltrials.gov/study/NCT07225140" }, { "nct_id": "NCT07839936", "title": "A Study of VERVE-102 (LY4636581) in Adults With or at High Risk for Cardiovascular Disease", "status": "NOT_YET_RECRUITING", "phase": "Phase 2", "lead_sponsor": "Verve Therapeutics, Inc.", "conditions": [ "Atherosclerosis", "Cardiovascular Disease", "Hypercholesterolemia" ], "sites": [ "DeSoto" ], "enrollment": 175, "start_date": "2026-10", "registry_url": "https://clinicaltrials.gov/study/NCT07839936" }, { "nct_id": "NCT07536282", "title": "Evaluation of NWRD09 for Female Participants With Persistent HPV16 Infection", "status": "NOT_YET_RECRUITING", "phase": "Phase 1/2", "lead_sponsor": "Newish Biotech (Wuxi) Co., Ltd.", "conditions": [ "Persistent HPV16 Infection" ], "sites": [ "New York" ], "enrollment": 78, "start_date": "2026-10", "registry_url": "https://clinicaltrials.gov/study/NCT07536282" }, { "nct_id": "NCT07763873", "title": "A Study Examining Acceptability of Auditory Implant Fitting Software Technologies", "status": "NOT_YET_RECRUITING", "phase": "Not applicable", "lead_sponsor": "Cochlear", "conditions": [ "Hearing Impairment" ], "sites": [ "Lone Tree" ], "enrollment": 200, "start_date": "2026-10", "registry_url": "https://clinicaltrials.gov/study/NCT07763873" }, { "nct_id": "NCT07750678", "title": "Safety and Efficacy Study of GEB-101 Injection in Subjects With TGFBI-related Corneal Dystrophy", "status": "NOT_YET_RECRUITING", "phase": "Phase 1/2", "lead_sponsor": "GenEditBio Limited", "conditions": [ "Hereditary Corneal Dystrophy", "Corneal Abnormality", "Corneal Dystrophies", "Corneal Dystrophies, Hereditary" ], "sites": [ "Los Angeles" ], "enrollment": 30, "start_date": "2026-10", "registry_url": "https://clinicaltrials.gov/study/NCT07750678" }, { "nct_id": "NCT07867327", "title": "A Study of LY4515100 in Healthy Male Participants", "status": "NOT_YET_RECRUITING", "phase": "Phase 1", "lead_sponsor": "Eli Lilly and Company", "conditions": [ "Healthy" ], "sites": [ "Madison" ], "enrollment": 16, "start_date": "2026-10", "registry_url": "https://clinicaltrials.gov/study/NCT07867327" }, { "nct_id": "NCT07511556", "title": "First-in-human Study of UX016 in GNEM", "status": "RECRUITING", "phase": "Phase 1/2", "lead_sponsor": "Ultragenyx Pharmaceutical Inc", "conditions": [ "GNE Myopathy" ], "sites": [ "Orange", "Iselin" ], "enrollment": 24, "start_date": "2026-10", "registry_url": "https://clinicaltrials.gov/study/NCT07511556" }, { "nct_id": "NCT07800871", "title": "FT839 in Autoimmune Diseases", "status": "RECRUITING", "phase": "Phase 1/2", "lead_sponsor": "Fate Therapeutics", "conditions": [ "ANCA-Associated Vasculitis (AAV)", "Idiopathic Inflammatory Myositis (IIM)", "Rheumatoid Arthritis (RA)", "Systemic Lupus Erythematosus (SLE)" ], "sites": [ "Fullerton" ], "enrollment": 446, "start_date": "2026-10", "registry_url": "https://clinicaltrials.gov/study/NCT07800871" }, { "nct_id": "NCT07896850", "title": "Conversational AI for Adult Flu Vaccination Decisions", "status": "NOT_YET_RECRUITING", "phase": "Not applicable", "lead_sponsor": "Calypta Systems, Inc.", "conditions": [ "Influenza, Human", "Vaccine Hesitancy" ], "sites": [ "San Francisco" ], "enrollment": 220, "start_date": "2026-10", "registry_url": "https://clinicaltrials.gov/study/NCT07896850" }, { "nct_id": "NCT07881952", "title": "Safety and Systemic Exposure of YCANTH (VP-102) in Subjects With Common Warts (Verruca Vulgaris) (COVE-5)", "status": "NOT_YET_RECRUITING", "phase": "Phase 2", "lead_sponsor": "Verrica Pharmaceuticals Inc.", "conditions": [ "Common Warts", "Common Warts (Verruca Vulgaris)", "Human Papilloma Virus (HPV)", "Warts" ], "sites": [ "Bowling Green", "Owensboro", "New York", "The Bronx" ], "enrollment": 30, "start_date": "2026-10", "registry_url": "https://clinicaltrials.gov/study/NCT07881952" }, { "nct_id": "NCT07869147", "title": "Study of ORJ-001 for the Treatment of IPF", "status": "RECRUITING", "phase": "Phase 2", "lead_sponsor": "Oorja Bio, Inc.", "conditions": [ "Idiopathic Pulmonary Fibrosis" ], "sites": [ "Doral", "DuBois" ], "enrollment": 95, "start_date": "2026-10", "registry_url": "https://clinicaltrials.gov/study/NCT07869147" }, { "nct_id": "NCT07864714", "title": "UltraTrac Clinical Pilot Study", "status": "NOT_YET_RECRUITING", "phase": "Observational", "lead_sponsor": "AcQumen Medical, Inc.", "conditions": [ "Hemodynamic Monitoring" ], "sites": [ "Washington D.C." ], "enrollment": 50, "start_date": "2026-10", "registry_url": "https://clinicaltrials.gov/study/NCT07864714" }, { "nct_id": "NCT07083765", "title": "Renal Artery Denervation Assessment Without Antihypertensive Medication Regimen (RADAR)", "status": "NOT_YET_RECRUITING", "phase": "Phase 3", "lead_sponsor": "Ablative Solutions, Inc.", "conditions": [ "Hypertension", "Hypertension,Essential" ], "sites": [ "Knoxville" ], "enrollment": 202, "start_date": "2026-10", "registry_url": "https://clinicaltrials.gov/study/NCT07083765" }, { "nct_id": "NCT07881887", "title": "A Study of LY4167586 in Participants With Obesity or Overweight With or Without Type 2 Diabetes", "status": "NOT_YET_RECRUITING", "phase": "Phase 1", "lead_sponsor": "Eli Lilly and Company", "conditions": [ "Obesity", "Overweight", "Diabetes Mellitus, Type 2" ], "sites": [ "Anaheim", "Los Alamitos", "Walnut Creek", "Daytona Beach", "Miami", "Winter Park", "Decatur", "Marlton" ], "enrollment": 617, "start_date": "2026-10", "registry_url": "https://clinicaltrials.gov/study/NCT07881887" }, { "nct_id": "NCT07839286", "title": "Jigsawdio Multisensory Platform for People With Mild Cognitive Impairment, Alzheimer's Disease, or Related Dementias", "status": "NOT_YET_RECRUITING", "phase": "Not applicable", "lead_sponsor": "Callahan-Young LLC DBA Jigsawdio", "conditions": [ "Alzheimer Disease", "Dementia", "Mild Cognitive Impairment" ], "sites": [ "Durham", "College Station" ], "enrollment": 80, "start_date": "2026-10", "registry_url": "https://clinicaltrials.gov/study/NCT07839286" }, { "nct_id": "NCT05847179", "title": "Phase 2, Open-Label Study to Evaluate the Safety and Tolerability of Progerinin in Werner Syndrome", "status": "RECRUITING", "phase": "Phase 2", "lead_sponsor": "PRG Science & Technology Co., Ltd.", "conditions": [ "Werner Syndrome" ], "sites": [ "Ann Arbor" ], "enrollment": 5, "start_date": "2026-10", "registry_url": "https://clinicaltrials.gov/study/NCT05847179" }, { "nct_id": "NCT07862582", "title": "RYZ711 Diagnostic Platform Study", "status": "NOT_YET_RECRUITING", "phase": "Phase 1/2", "lead_sponsor": "RayzeBio, Inc.", "conditions": [ "Prostate Cancer (Adenocarcinoma)", "Adenocarcinoma of the Prostate", "Metastatic Castration-resistant Prostate Cancer (mCRPC)", "Metastatic Hormone-Sensitive Prostate Cancer (mHSPC)" ], "sites": [ "Omaha" ], "enrollment": 116, "start_date": "2026-10", "registry_url": "https://clinicaltrials.gov/study/NCT07862582" }, { "nct_id": "NCT07616206", "title": "Cadisegliatin as Adjunctive Therapy to Insulin in Participants With Type 1 Diabetes Who Are Using Hybrid Closed Loop (HCL) Systems", "status": "NOT_YET_RECRUITING", "phase": "Phase 2", "lead_sponsor": "vTv Therapeutics", "conditions": [ "Type 1 Diabetes (T1D)" ], "sites": [ "Atlanta" ], "enrollment": 40, "start_date": "2026-10", "registry_url": "https://clinicaltrials.gov/study/NCT07616206" }, { "nct_id": "NCT07710196", "title": "A 24-Month Trial of NPI-001 for the Preservation of Photoreceptors in Retinitis Pigmentosa Associated With Usher Syndrome", "status": "RECRUITING", "phase": "Phase 3", "lead_sponsor": "Nacuity Pharmaceuticals, Inc.", "conditions": [ "Retinitis Pigmentosa (RP)", "Usher Syndrome" ], "sites": [ "Dallas" ], "enrollment": 80, "start_date": "2026-10", "registry_url": "https://clinicaltrials.gov/study/NCT07710196" }, { "nct_id": "NCT07611305", "title": "ProGo Menopause Wellbeing Study", "status": "NOT_YET_RECRUITING", "phase": "Not applicable", "lead_sponsor": "Hofseth Biocare ASA", "conditions": [ "Menopause Related Conditions" ], "sites": [ "San Francisco" ], "enrollment": 100, "start_date": "2026-10", "registry_url": "https://clinicaltrials.gov/study/NCT07611305" }, { "nct_id": "NCT07903480", "title": "A Clinical Trial to Evaluate the Effects of A Supplement on Symptoms of Menopause and Overall Well-being", "status": "NOT_YET_RECRUITING", "phase": "Not applicable", "lead_sponsor": "Primal Harvest, LLC", "conditions": [ "Menopause", "Menopausal Symptoms", "Hot Flashes", "Night Sweats" ], "sites": [ "Las Vegas" ], "enrollment": 40, "start_date": "2026-10", "registry_url": "https://clinicaltrials.gov/study/NCT07903480" }, { "nct_id": "NCT07874620", "title": "A Study of Cebranopadol for Opioid Withdrawal Symptoms in Adults With Chronic Pain", "status": "RECRUITING", "phase": "Phase 2", "lead_sponsor": "Adneuris Therapeutics, Inc.", "conditions": [ "Chronic Pain", "Pain", "Opioid Withdrawal (Disorder)", "Opioid Use Disorder" ], "sites": [ "North Canton", "Houston" ], "enrollment": 45, "start_date": "2026-10", "registry_url": "https://clinicaltrials.gov/study/NCT07874620" }, { "nct_id": "NCT07526974", "title": "A Study to Evaluate the Efficacy and Safety of CBL-514 Injection for Reducing Subcutaneous Fat ( SUPREME-02 )", "status": "NOT_YET_RECRUITING", "phase": "Phase 3", "lead_sponsor": "Caliway Biopharmaceuticals Co., Ltd.", "conditions": [ "Subcutaneous Fat" ], "sites": [ "Encinitas", "Aventura", "Alpharetta", "Hunt Valley", "Omaha", "New York", "Canal Winchester", "Nashville" ], "enrollment": 320, "start_date": "2026-10", "registry_url": "https://clinicaltrials.gov/study/NCT07526974" }, { "nct_id": "NCT07901751", "title": "Study to Evaluate the Efficacy of a Single Intravitreal Injection of RTx-015 in Participants With Retinitis Pigmentosa (PERCEPT)", "status": "RECRUITING", "phase": "Phase 2/3", "lead_sponsor": "Ray Therapeutics, Inc.", "conditions": [ "Retinitis Pigmentosa (RP)", "Inherited Retinal Diseases" ], "sites": [ "Phoenix", "Bakersfield", "Beverly Hills", "Santa Barbara", "Deerfield Beach", "\u2018Aiea", "Oak Park", "Detroit" ], "enrollment": 60, "start_date": "2026-10", "registry_url": "https://clinicaltrials.gov/study/NCT07901751" }, { "nct_id": "NCT07729137", "title": "Study of EO2002 in Subjects With Corneal Edema Secondary to Corneal Endothelial Dysfunction", "status": "RECRUITING", "phase": "Phase 2", "lead_sponsor": "Emmecell", "conditions": [ "Corneal Edema", "Fuchs", "Fuchs Dystrophy", "Fuchs' Endothelial Dystrophy" ], "sites": [ "Torrance", "Largo", "Atlanta", "Chicago", "Carmel", "Overland Park", "Minnetonka", "Kansas City" ], "enrollment": 121, "start_date": "2026-10", "registry_url": "https://clinicaltrials.gov/study/NCT07729137" }, { "nct_id": "NCT07672769", "title": "Bexmarilimab + Azacitidine Versus Placebo + Azacitidine in Participants With Treatment-na\u00efve Higher-risk Myelodysplastic Syndromes", "status": "RECRUITING", "phase": "Phase 2", "lead_sponsor": "Faron Pharmaceuticals Ltd", "conditions": [ "Higher Risk Myelodysplastic Syndromes" ], "sites": [ "Duarte", "Aurora", "New Haven", "Pembroke Pines", "Boston", "Chapel Hill", "Nashville", "Houston" ], "enrollment": 90, "start_date": "2026-10", "registry_url": "https://clinicaltrials.gov/study/NCT07672769" }, { "nct_id": "NCT07876050", "title": "A Clinical Trial to Evaluate the Effects of the Kaia Relief - Cycle System on Premenstrual Symptom Severity, Menstrual Discomfort, and Overall Well-Being in Premenopausal Women.", "status": "RECRUITING", "phase": "Not applicable", "lead_sponsor": "Vivance Group", "conditions": [ "Premenstrual Syndrome", "Menstrual Discomfort", "Premenstrual Symptoms" ], "sites": [ "Las Vegas" ], "enrollment": 45, "start_date": "2026-10", "registry_url": "https://clinicaltrials.gov/study/NCT07876050" }, { "nct_id": "NCT07882472", "title": "A Single Ascending Dose Study of DTI-117 Given Intramuscularly in Healthy Participants.", "status": "RECRUITING", "phase": "Phase 1", "lead_sponsor": "Dignify Therapeutics", "conditions": [ "Healthy Adult" ], "sites": [ "Austin" ], "enrollment": 40, "start_date": "2026-10", "registry_url": "https://clinicaltrials.gov/study/NCT07882472" }, { "nct_id": "NCT07883278", "title": "A Descriptive Analysis of the Physiological and Behavioral Profiles of Elite Female Athletes", "status": "ENROLLING_BY_INVITATION", "phase": "Observational", "lead_sponsor": "PepsiCo Global R&D", "conditions": [ "Female Athletes", "Healthy Women" ], "sites": [ "Bradenton" ], "enrollment": 50, "start_date": "2026-10", "registry_url": "https://clinicaltrials.gov/study/NCT07883278" }, { "nct_id": "NCT07848594", "title": "The Impact of Overnight Active Temperature Regulation on the Gut Microbiome, Inflammation, and Circadian Rhythm.", "status": "RECRUITING", "phase": "Not applicable", "lead_sponsor": "Eight Sleep Inc.", "conditions": [ "Poor Sleep Quality", "Gut Microbiome", "Gut Health", "Inflammation" ], "sites": [ "Newton Center" ], "enrollment": 100, "start_date": "2026-10", "registry_url": "https://clinicaltrials.gov/study/NCT07848594" }, { "nct_id": "NCT07743541", "title": "Study of TUB-040 in Patients With Recurrent or Progressive Uterine Cancer After Chemotherapy and Immune Therapy", "status": "NOT_YET_RECRUITING", "phase": "Phase 1/2", "lead_sponsor": "Gilead Sciences", "conditions": [ "Uterine Endometrial Cancer" ], "sites": [ "Los Angeles", "East Brunswick", "Lake Success", "West Valley City" ], "enrollment": 100, "start_date": "2026-10", "registry_url": "https://clinicaltrials.gov/study/NCT07743541" }, { "nct_id": "NCT07881120", "title": "Study of Afimetoran in Adults With Cutaneous Lupus Erythematosus", "status": "RECRUITING", "phase": "Phase 2/3", "lead_sponsor": "Beeline Medicines Corporation", "conditions": [ "Cutaneous Lupus Erythematosus (CLE)", "Systematic Lupus Erythematosus" ], "sites": [ "San Diego", "DeBary", "Missoula" ], "enrollment": 390, "start_date": "2026-10", "registry_url": "https://clinicaltrials.gov/study/NCT07881120" }, { "nct_id": "NCT07830550", "title": "Blood Donation Study for ALPCO Syphilis-T and Syphilis-NT Assay Development", "status": "ENROLLING_BY_INVITATION", "phase": "Observational", "lead_sponsor": "American Laboratory Products Company", "conditions": [ "Healthy Volunteers", "Syphilis Serologic Assay Development", "Blood Specimen Collection", "Diagnostic Assay Development" ], "sites": [ "Salem" ], "enrollment": 50, "start_date": "2026-10", "registry_url": "https://clinicaltrials.gov/study/NCT07830550" }, { "nct_id": "NCT07760961", "title": "Effect of Mizagliflozin on Hypoglycemia in Patients With Post-Bariatric Hypoglycemia", "status": "RECRUITING", "phase": "Phase 2", "lead_sponsor": "Vogenx, Inc.", "conditions": [ "Postbariatric Hypoglycemia" ], "sites": [ "Chula Vista", "Palo Alto", "Aurora", "Doral", "Lawrenceville", "Morehead City", "Philadelphia", "Nashville" ], "enrollment": 36, "start_date": "2026-10", "registry_url": "https://clinicaltrials.gov/study/NCT07760961" }, { "nct_id": "NCT07863193", "title": "Phase 3 Study of Denifanstat in Participants With Moderate to Severe Acne (AURORA)", "status": "RECRUITING", "phase": "Phase 3", "lead_sponsor": "Sagimet Biosciences Inc.", "conditions": [ "Acne Vulgaris" ], "sites": [ "Bryant", "Fremont", "Santa Ana", "Doral", "Fort Lauderdale", "Miami", "Miramar", "Lincolnshire" ], "enrollment": 800, "start_date": "2026-10", "registry_url": "https://clinicaltrials.gov/study/NCT07863193" }, { "nct_id": "NCT07901179", "title": "A Study to Evaluate the Safety and Efficacy of ALKS 7290 as an Adjunctive Therapy to Antidepressants in Adult Participants With Major Depressive Disorder", "status": "RECRUITING", "phase": "Phase 2", "lead_sponsor": "Alkermes, Inc.", "conditions": [ "Major Depressive Disorder (MDD)" ], "sites": [ "Jacksonville" ], "enrollment": 180, "start_date": "2026-10", "registry_url": "https://clinicaltrials.gov/study/NCT07901179" }, { "nct_id": "NCT07851389", "title": "A First-in-Human Feasibility Study of the Vibrant Stroke Detection Technology During Carotid Endarterectomies", "status": "NOT_YET_RECRUITING", "phase": "Observational", "lead_sponsor": "Vibrant Medical Ltd.", "conditions": [ "Carotid Stenosis" ], "sites": [ "Tampa" ], "enrollment": 10, "start_date": "2026-10", "registry_url": "https://clinicaltrials.gov/study/NCT07851389" }, { "nct_id": "NCT06458907", "title": "A Prospective, Randomized Multicenter Clinical Trial of the TricValve\u00ae Transcatheter Bicaval Valve System in Subjects With Severe Tricuspid Regurgitation.", "status": "NOT_YET_RECRUITING", "phase": "Not applicable", "lead_sponsor": "P+F Products + Features USA Inc.", "conditions": [ "Tricuspid Valve Disease", "Heart Valve Diseases", "Cardiovascular Diseases", "Heart Failure" ], "sites": [ "Birmingham", "Phoenix", "Sacramento", "San Diego", "San Francisco", "San Jose", "Washington D.C.", "Delray Beach" ], "enrollment": 780, "start_date": "2026-10", "registry_url": "https://clinicaltrials.gov/study/NCT06458907" }, { "nct_id": "NCT07843459", "title": "A Study of LY4560736 in Healthy Participants and Participants With Alzheimer's Disease (AD)", "status": "NOT_YET_RECRUITING", "phase": "Phase 1", "lead_sponsor": "Eli Lilly and Company", "conditions": [ "Healthy Volunteers", "Alzheimer Disease", "Amyloid", "Plaque, Amyloid" ], "sites": [ "Anaheim", "Irvine", "Los Alamitos", "Daytona Beach", "Lady Lake", "Maitland", "Orlando", "Port Orange" ], "enrollment": 111, "start_date": "2026-10", "registry_url": "https://clinicaltrials.gov/study/NCT07843459" }, { "nct_id": "NCT07896902", "title": "Xenon MRI to Evaluate Changes to Lung Function Following Bronchoscopic Treatment of Air Trapping in Emphysema", "status": "RECRUITING", "phase": "Early Phase 1", "lead_sponsor": "Apreo Health, Inc.", "conditions": [ "Air Trapping", "Emphysema", "Hyperinflation" ], "sites": [ "Birmingham", "Kansas City" ], "enrollment": 15, "start_date": "2026-10", "registry_url": "https://clinicaltrials.gov/study/NCT07896902" }, { "nct_id": "NCT07429838", "title": "RENEW: Study of Porcine Liver Support in Participants With Acute-on-Chronic Liver Failure", "status": "NOT_YET_RECRUITING", "phase": "Phase 1/2", "lead_sponsor": "eGenesis, INC", "conditions": [ "Acute on Chronic Liver Failure (ACLF)", "Hepatic Encephalopathy (HE)" ], "sites": [ "St Louis", "Madison" ], "enrollment": 20, "start_date": "2026-10", "registry_url": "https://clinicaltrials.gov/study/NCT07429838" }, { "nct_id": "NCT07681778", "title": "Safety and Tolerability of Subretinal OPGx-RDH12-1001 for LCA-Associated Inherited Retinal Degeneration (LCA-IRD)", "status": "RECRUITING", "phase": "Phase 1/2", "lead_sponsor": "Opus Genetics, Inc", "conditions": [ "Leber Congenital Amaurosis", "Leber Congenital Amaurosis (LCA)" ], "sites": [ "Phoenix", "Philadelphia", "Dallas", "Houston" ], "enrollment": 10, "start_date": "2026-10", "registry_url": "https://clinicaltrials.gov/study/NCT07681778" }, { "nct_id": "NCT07219238", "title": "Study to Evaluate the Diagnostic Performance of GEH300079 (68Ga) Injection PET/CT for Detection of PC in Patients With Colorectal, Gastric, Ovarian, or Pancreatic Cancers (PERISCOPE)", "status": "RECRUITING", "phase": "Phase 2/3", "lead_sponsor": "GE Healthcare", "conditions": [ "Colorectal Cancer", "Gastric Cancers", "Ovarian Cancers", "Pancreatic Ductal Adenocarcinoma" ], "sites": [ "Grand Rapids" ], "enrollment": 175, "start_date": "2026-10", "registry_url": "https://clinicaltrials.gov/study/NCT07219238" }, { "nct_id": "NCT07872033", "title": "Aleniglipron Hepatic Impairment Study", "status": "NOT_YET_RECRUITING", "phase": "Phase 1", "lead_sponsor": "Gasherbrum Bio, Inc., a wholly owned subsidiary of Structure Therapeutics", "conditions": [ "Hepatic Impairment" ], "sites": [ "Orlando", "San Antonio" ], "enrollment": 36, "start_date": "2026-10", "registry_url": "https://clinicaltrials.gov/study/NCT07872033" }, { "nct_id": "NCT07827014", "title": "An Open-Label, Two-Arm Pilot Study of the Tolerability, Consumer Acceptability, and Exploratory Well-Being Outcomes of a Multi-Ingredient Protein Formula in Two Flavors in Healthy Adults", "status": "RECRUITING", "phase": "Not applicable", "lead_sponsor": "Qualia Life Sciences", "conditions": [ "Healthy" ], "sites": [ "Carlsbad" ], "enrollment": 50, "start_date": "2026-10", "registry_url": "https://clinicaltrials.gov/study/NCT07827014" }, { "nct_id": "NCT07723469", "title": "Phase 3 Trial of SRG-514 Administered Intraoperatively to Patients Undergoing Breast-Conserving Surgery", "status": "NOT_YET_RECRUITING", "phase": "Phase 3", "lead_sponsor": "SURGE Therapeutics", "conditions": [ "TNBC - Triple-Negative Breast Cancer" ], "sites": [ "Rochester", "New York", "Durham" ], "enrollment": 400, "start_date": "2026-10", "registry_url": "https://clinicaltrials.gov/study/NCT07723469" }, { "nct_id": "NCT06752356", "title": "A Study Investigating Intravenous Human Normal Immune Globulin (IGIV) 10% KIg10 (QIVIGY) in Subjects With Chronic Inflammatory Demyelinating Polyneuropathy (CIDP)", "status": "RECRUITING", "phase": "Phase 3", "lead_sponsor": "Kedrion S.p.A.", "conditions": [ "Chronic Inflammatory Demyelinating Polyneuropathy" ], "sites": [ "Stamford", "Miami", "Tampa", "Lebanon", "El Paso" ], "enrollment": 161, "start_date": "2026-10", "registry_url": "https://clinicaltrials.gov/study/NCT06752356" }, { "nct_id": "NCT07848256", "title": "Hydration, Ergonomic Risk, and Fatigue Across Multiple PepsiCo Facilities", "status": "ENROLLING_BY_INVITATION", "phase": "Observational", "lead_sponsor": "PepsiCo Global R&D", "conditions": [ "Hydration Status and Ergonomic Risk in Frontline Workers" ], "sites": [ "Orlando", "Tampa" ], "enrollment": 60, "start_date": "2026-10", "registry_url": "https://clinicaltrials.gov/study/NCT07848256" }, { "nct_id": "NCT07729995", "title": "BAFF CAR-T Cells (LMY-922) for Treatment of Refractory Autoimmune Disease", "status": "NOT_YET_RECRUITING", "phase": "Phase 1", "lead_sponsor": "Luminary Therapeutics", "conditions": [ "Rheumatoid Arthritis (RA)", "Systemic Lupus Erthematosus (SLE)", "Dermatomyositis (DM)", "Systemic Sclerosis (SSc)" ], "sites": [ "Boston" ], "enrollment": 94, "start_date": "2026-10", "registry_url": "https://clinicaltrials.gov/study/NCT07729995" }, { "nct_id": "NCT07840326", "title": "A Phase 2a Study of SUN-627 in Participants With Non-Active Secondary Progressive and Primary Progressive Multiple Sclerosis (SPMS/PPMS)", "status": "RECRUITING", "phase": "Phase 2", "lead_sponsor": "Sundance Biosciences, Inc.", "conditions": [ "Primary Progressive Multiple Sclerosis", "Primary Progressive MS", "Primary Progressive Multiple Sclerosis (PPMS)", "Secondary Progressive MS (SPMS)" ], "sites": [ "Tampa", "Atlanta", "Stony Brook", "Raleigh", "Columbus", "Oklahoma City", "Dallas" ], "enrollment": 20, "start_date": "2026-10", "registry_url": "https://clinicaltrials.gov/study/NCT07840326" }, { "nct_id": "NCT07867288", "title": "Study to Assess the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of HTX-001", "status": "RECRUITING", "phase": "Phase 1", "lead_sponsor": "Haya Therapeutics, Inc.", "conditions": [ "Nonobstructive Hypertrophic Cardiomyopathy" ], "sites": [ "Boston", "Kansas City", "Cincinnati" ], "enrollment": 10, "start_date": "2026-10", "registry_url": "https://clinicaltrials.gov/study/NCT07867288" }, { "nct_id": "NCT07814417", "title": "A Study of Olomorasib (LY3537982) in Participants With Advanced Colorectal Cancer and a KRAS G12C Mutation", "status": "NOT_YET_RECRUITING", "phase": "Phase 2", "lead_sponsor": "Eli Lilly and Company", "conditions": [ "Colorectal Neoplasms" ], "sites": [ "Birmingham", "Los Angeles", "Orlando", "Boston", "East Brunswick", "Austin", "Fairfax", "Falls Church" ], "enrollment": 50, "start_date": "2026-10", "registry_url": "https://clinicaltrials.gov/study/NCT07814417" }, { "nct_id": "NCT07592299", "title": "To Establish the Safety and Effectiveness of the ALPFA GRAIL PFA System for Treating Symptomatic Benign Prostate Hyperplasia (BPH) Also Known as an Enlarged Prostate.", "status": "RECRUITING", "phase": "Not applicable", "lead_sponsor": "ALPFA Medical", "conditions": [ "Benign Prostatic Hyperplasia (BPH)" ], "sites": [ "Germantown" ], "enrollment": 250, "start_date": "2026-10", "registry_url": "https://clinicaltrials.gov/study/NCT07592299" }, { "nct_id": "NCT07339384", "title": "Signatera Assessment in Early-Stage Endometrial Cancer", "status": "NOT_YET_RECRUITING", "phase": "Not applicable", "lead_sponsor": "Natera, Inc.", "conditions": [ "Endometrial Cancer" ], "sites": [ "Birmingham", "La Jolla", "Los Angeles", "Miami", "Chicago", "Minneapolis", "New York", "Charlotte" ], "enrollment": 1010, "start_date": "2026-10", "registry_url": "https://clinicaltrials.gov/study/NCT07339384" }, { "nct_id": "NCT07559175", "title": "A Study to Evaluate Safety and Explore Efficacy of New Lipase NHS7108 in Adult Participants With Exocrine Pancreatic Insufficiency.", "status": "RECRUITING", "phase": "Phase 2", "lead_sponsor": "Aimmune Nestl\u00e9 Health Science US R&D, LLC", "conditions": [ "Exocrine Pancreatic Insufficiency (EPI)", "Cystic Fibrosis (CF)", "Pancreatic Enzyme Abnormality", "Pancreatic Diseases" ], "sites": [ "Scottsdale", "Little Rock", "Los Angeles", "Doral", "Orlando", "Lenexa", "Baltimore", "Billings" ], "enrollment": 66, "start_date": "2026-10", "registry_url": "https://clinicaltrials.gov/study/NCT07559175" }, { "nct_id": "NCT07834372", "title": "REWRITE-CAD Protocol: Risk Evaluation With AI-CPA to Reduce Progression and Improve Lifetime Care for Patients With Known Coronary Artery Disease", "status": "NOT_YET_RECRUITING", "phase": "Not applicable", "lead_sponsor": "HeartFlow, Inc.", "conditions": [ "CAD - Coronary Artery Disease" ], "sites": [ "Greensboro" ], "enrollment": 350, "start_date": "2026-10", "registry_url": "https://clinicaltrials.gov/study/NCT07834372" }, { "nct_id": "NCT07644195", "title": "Study to Evaluate Safety and Activity of Inhaled TRL1068 in Healthy Volunteers", "status": "NOT_YET_RECRUITING", "phase": "Phase 1", "lead_sponsor": "Trellis Bioscience LLC", "conditions": [ "Healthy Volunteer" ], "sites": [ "Lincoln" ], "enrollment": 14, "start_date": "2026-10", "registry_url": "https://clinicaltrials.gov/study/NCT07644195" }, { "nct_id": "NCT07426419", "title": "An AAV Gene Therapy Trial of AFTX-201 in Adults With BAG3-Associated Dilated Cardiomyopathy (DCM)", "status": "RECRUITING", "phase": "Phase 1/2", "lead_sponsor": "Affinia Therapeutics", "conditions": [ "Dilated Cardiomyopathy (DCM)", "BAG3 Mutation Associated Dilated Cardiomyopathy" ], "sites": [ "Miami", "Kansas City", "New York", "Houston" ], "enrollment": 22, "start_date": "2026-10", "registry_url": "https://clinicaltrials.gov/study/NCT07426419" }, { "nct_id": "NCT07675408", "title": "Validation of cueStim for Reduction of Freezing of Gait in Parkinson's Disease", "status": "NOT_YET_RECRUITING", "phase": "Not applicable", "lead_sponsor": "Fortis Medical Devices Limited", "conditions": [ "Parkinson's Disease With Freezing of Gait" ], "sites": [ "Boca Raton", "Daytona Beach", "Atlanta", "Kansas City", "Portland", "Kirkland" ], "enrollment": 60, "start_date": "2026-10", "registry_url": "https://clinicaltrials.gov/study/NCT07675408" }, { "nct_id": "NCT07468370", "title": "Real Time Craniotomy Planning Using Mixed Reality", "status": "NOT_YET_RECRUITING", "phase": "Observational", "lead_sponsor": "Brainlab AG", "conditions": [ "Neurosurgery", "Surgical Planning", "Brain Tumor Adult", "Craniotomy Tumor Removal Surgery" ], "sites": [ "Boston" ], "enrollment": 54, "start_date": "2026-10", "registry_url": "https://clinicaltrials.gov/study/NCT07468370" }, { "nct_id": "NCT07869043", "title": "A Study to Learn About the Study Medicine Called Tilrekimig ( PF-07275315) in People With Severe Asthma", "status": "RECRUITING", "phase": "Phase 3", "lead_sponsor": "Pfizer", "conditions": [ "Asthma" ], "sites": [ "Pittsburgh", "Austin", "Tomball" ], "enrollment": 1100, "start_date": "2026-09-30", "registry_url": "https://clinicaltrials.gov/study/NCT07869043" }, { "nct_id": "NCT07843498", "title": "A Phase III Study to Evaluate the Efficacy and Safety of Petrelintide in Participants With Overweight or Obesity", "status": "RECRUITING", "phase": "Phase 3", "lead_sponsor": "Hoffmann-La Roche", "conditions": [ "Obesity or Overweight" ], "sites": [ "Anniston", "Port Orange", "Nashville" ], "enrollment": 3900, "start_date": "2026-09-30", "registry_url": "https://clinicaltrials.gov/study/NCT07843498" }, { "nct_id": "NCT06840496", "title": "To Investigate the Efficacy of Treatment With Oral NA-921 (Bionetide) Versus Placebo in Females With Rett Syndrome", "status": "RECRUITING", "phase": "Phase 3", "lead_sponsor": "Biomed Industries, Inc.", "conditions": [ "Rett Syndrome" ], "sites": [ "Phoenix", "La Jolla", "Los Angeles", "Sacramento", "San Francisco", "Aurora", "Tampa", "Chicago" ], "enrollment": 210, "start_date": "2026-09-30", "registry_url": "https://clinicaltrials.gov/study/NCT06840496" }, { "nct_id": "NCT07879638", "title": "A Study to Determine the Effect of Access to Multiple Tobacco Flavor Options on Smoking Abstinence Among Primary Cigarette Smokers Using an Electronic Nicotine Delivery System", "status": "RECRUITING", "phase": "Not applicable", "lead_sponsor": "RAI Services Company", "conditions": [ "Smoking", "Tobacco" ], "sites": [ "Fort Lauderdale", "Atlanta", "Chicago", "Iselin", "Dallas" ], "enrollment": 480, "start_date": "2026-09-30", "registry_url": "https://clinicaltrials.gov/study/NCT07879638" }, { "nct_id": "NCT07843472", "title": "A Phase III Study to Evaluate the Efficacy and Safety of Petrelintide in Participants With Overweight or Obesity and Established Cardiovascular Disease", "status": "RECRUITING", "phase": "Phase 3", "lead_sponsor": "Hoffmann-La Roche", "conditions": [ "Obesity or Overweight", "Cardiovascular Disease" ], "sites": [ "Anniston", "Los Angeles", "Port Orange" ], "enrollment": 2500, "start_date": "2026-09-30", "registry_url": "https://clinicaltrials.gov/study/NCT07843472" }, { "nct_id": "NCT07520006", "title": "Study of NX-5948 in Combination With Other Agents in Adults With B-cell Malignancies", "status": "RECRUITING", "phase": "Phase 1/2", "lead_sponsor": "Nurix Therapeutics, Inc.", "conditions": [ "B-cell Lymphoma", "Chronic Lymphocytic Leukemia", "Small Lymphocytic Lymphoma" ], "sites": [ "Aurora", "Coral Gables", "Eugene", "Pittsburgh", "Nashville", "Tyler" ], "enrollment": 150, "start_date": "2026-09-30", "registry_url": "https://clinicaltrials.gov/study/NCT07520006" }, { "nct_id": "NCT07843485", "title": "A Phase III Study to Evaluate the Efficacy and Safety of Petrelintide in Participants With Overweight or Obesity and Type 2 Diabetes", "status": "RECRUITING", "phase": "Phase 3", "lead_sponsor": "Hoffmann-La Roche", "conditions": [ "Obesity or Overweight", "Type 2 Diabetes" ], "sites": [ "Los Angeles", "Manassas" ], "enrollment": 600, "start_date": "2026-09-30", "registry_url": "https://clinicaltrials.gov/study/NCT07843485" }, { "nct_id": "NCT07572162", "title": "Post-market Safety Study of LUMISIGHT", "status": "RECRUITING", "phase": "Observational", "lead_sponsor": "Lumicell, Inc.", "conditions": [ "Hypersensitivity Reactions" ], "sites": [ "Mobile", "Palo Alto" ], "enrollment": 1500, "start_date": "2026-09-30", "registry_url": "https://clinicaltrials.gov/study/NCT07572162" }, { "nct_id": "NCT07868419", "title": "Idiopathic Pulmonary Fibrosis (IPF)-Related Chronic Cough Reduction With Nalbuphine (NAL) Extended-Release (ER) Tablets", "status": "RECRUITING", "phase": "Phase 3", "lead_sponsor": "Trevi Therapeutics", "conditions": [ "Idiopathic Pulmonary Fibrosis" ], "sites": [ "Wilmington", "North Miami Beach", "Charlotte", "Sugar Land" ], "enrollment": 201, "start_date": "2026-09-30", "registry_url": "https://clinicaltrials.gov/study/NCT07868419" }, { "nct_id": "NCT07872982", "title": "BrainProtect-guided, Real-time Cerebral Autoregulation Monitoring and Protection of Brain During Cardiac Surgery With Cardiopulmonary Bypass Requiring Heart-lung Machine", "status": "NOT_YET_RECRUITING", "phase": "Not applicable", "lead_sponsor": "Scienceforbrain, UAB", "conditions": [ "Cerebral Autoregulation Impairment", "Postoperative Cognitive Dysfunction", "Postoperative Delirium" ], "sites": [ "Chicago" ], "enrollment": 304, "start_date": "2026-09-30", "registry_url": "https://clinicaltrials.gov/study/NCT07872982" }, { "nct_id": "NCT07531043", "title": "Efficacy and Safety of FID 123472 Ophthalmic Solution for Ocular Redness in Adults", "status": "RECRUITING", "phase": "Phase 3", "lead_sponsor": "Alcon Research", "conditions": [ "Ocular Hyperemia" ], "sites": [ "Los Angeles", "Newport Beach", "Pittsburg", "Louisville", "Andover", "Apex", "Cranberry Township", "Smyrna" ], "enrollment": 230, "start_date": "2026-09-30", "registry_url": "https://clinicaltrials.gov/study/NCT07531043" }, { "nct_id": "NCT07616856", "title": "Post-market Evaluation of LumiSystem: Intraoperative Margin Performance and Clinical Utility (IMPACT) Registry", "status": "RECRUITING", "phase": "Observational", "lead_sponsor": "Lumicell, Inc.", "conditions": [ "Breast Cancer" ], "sites": [ "Mobile", "Palo Alto" ], "enrollment": 1500, "start_date": "2026-09-30", "registry_url": "https://clinicaltrials.gov/study/NCT07616856" }, { "nct_id": "NCT07807969", "title": "An Open-label Extension Study of the Long-Term Safety of Vonaprument (ANX007) in Participants With Dry Age-Related Macular Degeneration (AMD) With Geographic Atrophy (GA)", "status": "NOT_YET_RECRUITING", "phase": "Phase 3", "lead_sponsor": "Annexon, Inc.", "conditions": [ "Geographic Atrophy" ], "sites": [ "Sarasota", "St. Petersburg", "Hagerstown", "Springfield", "Asheville", "Eugene" ], "enrollment": 605, "start_date": "2026-09-30", "registry_url": "https://clinicaltrials.gov/study/NCT07807969" }, { "nct_id": "NCT07845500", "title": "A Study to Learn About Switching to a Monthly Study Medicine Called Berobenatide (PF-08653944) to Help Keep Weight Off in People With Overweight or Obesity", "status": "RECRUITING", "phase": "Phase 3", "lead_sponsor": "Pfizer", "conditions": [ "Obesity", "Overweight and/or Obesity", "Overweight", "Treatment Of Obesity" ], "sites": [ "Birmingham", "Los Angeles", "Santa Ana", "Walnut Creek", "Jacksonville", "New Port Richey", "Oviedo", "Louisville" ], "enrollment": 660, "start_date": "2026-09-30", "registry_url": "https://clinicaltrials.gov/study/NCT07845500" }, { "nct_id": "NCT07336472", "title": "A Study of IBI3003 in Subjects With Relapsed or Refractory Multiple Myeloma", "status": "RECRUITING", "phase": "Phase 1/2", "lead_sponsor": "Fortvita Biologics (USA)Inc.", "conditions": [ "Multiple Myeloma" ], "sites": [ "Scottsdale", "Duarte", "Irvine", "Atlanta", "New York", "Houston" ], "enrollment": 360, "start_date": "2026-09-30", "registry_url": "https://clinicaltrials.gov/study/NCT07336472" }, { "nct_id": "NCT07849244", "title": "Sacroiliac Joint Fusion Intervention For Mobility, Pain Relief, and Lasting Improvement in Functional Recovery \"SIMPLIFY\"", "status": "ENROLLING_BY_INVITATION", "phase": "Observational", "lead_sponsor": "OrthoFundamentals, LLC", "conditions": [ "Degenerative Sacroiliitis", "Sacroiliac Disorder" ], "sites": [ "Post Falls" ], "enrollment": 200, "start_date": "2026-09-30", "registry_url": "https://clinicaltrials.gov/study/NCT07849244" }, { "nct_id": "NCT07782827", "title": "CHAMPION: A Study to Evaluate the Efficacy and Safety of Obudanersen (ION582) in Children and Adults With Angelman Syndrome (AS)", "status": "RECRUITING", "phase": "Phase 3", "lead_sponsor": "Ionis Pharmaceuticals, Inc.", "conditions": [ "Angelman Syndrome" ], "sites": [ "Carrboro" ], "enrollment": 30, "start_date": "2026-09-30", "registry_url": "https://clinicaltrials.gov/study/NCT07782827" }, { "nct_id": "NCT07808151", "title": "Neoadjuvant Pembrolizumab and Porustobart in Resectable pMMR/MSS Colon Cancer", "status": "RECRUITING", "phase": "Phase 2", "lead_sponsor": "Solstice Oncology, Inc.", "conditions": [ "Colon Cancer" ], "sites": [ "Los Angeles", "Tampa", "Chicago", "Baltimore", "Boston", "New York", "Cleveland", "Nashville" ], "enrollment": 100, "start_date": "2026-09-30", "registry_url": "https://clinicaltrials.gov/study/NCT07808151" }, { "nct_id": "NCT07831824", "title": "Dose Optimization and Diagnostic Performance in Prostate Cancer (SPARROW [Staging Prostate Cancer With Advanced RM2 Radiotracer Oncologic Workup])", "status": "RECRUITING", "phase": "Phase 2/3", "lead_sponsor": "Lantheus Medical Imaging", "conditions": [ "Prostate Cancer" ], "sites": [ "Grand Rapids" ], "enrollment": 408, "start_date": "2026-09-30", "registry_url": "https://clinicaltrials.gov/study/NCT07831824" }, { "nct_id": "NCT07718737", "title": "Global, Multicenter Study of AMT-116 Versus Investigator's Choice in Participants With Advanced or Metastatic Non-squamous EGFR-Wildtype Non-Small Cell Lung Cancer (NSCLC) With Progression on or After Platinum-Based Chemotherapy and Anti-PD-1/PD-L1 Immunotherapy", "status": "RECRUITING", "phase": "Phase 2/3", "lead_sponsor": "Multitude Therapeutics Inc.", "conditions": [ "NSCLC (Advanced Non-small Cell Lung Cancer)" ], "sites": [ "Port Saint Lucie", "Kingwood" ], "enrollment": 512, "start_date": "2026-09-30", "registry_url": "https://clinicaltrials.gov/study/NCT07718737" }, { "nct_id": "NCT07316153", "title": "Deep Sleep in Older Adults", "status": "RECRUITING", "phase": "Phase 2", "lead_sponsor": "Proactive Life Inc", "conditions": [ "Insomnia", "Insomnia Chronic" ], "sites": [ "New York" ], "enrollment": 180, "start_date": "2026-09-30", "registry_url": "https://clinicaltrials.gov/study/NCT07316153" }, { "nct_id": "NCT07379684", "title": "A Study of Amicidin-\u03b2 Topical Solution for Patients With Surgical or Traumatic Wound Infections", "status": "RECRUITING", "phase": "Phase 1", "lead_sponsor": "Macro Biologics, Inc.", "conditions": [ "Surgical Wound Infection", "Traumatic Wound Infection" ], "sites": [ "Torrance", "Idaho Falls", "Baltimore", "St Louis", "Columbus" ], "enrollment": 44, "start_date": "2026-09-30", "registry_url": "https://clinicaltrials.gov/study/NCT07379684" }, { "nct_id": "NCT07775924", "title": "A Study to Assess the Efficacy and Safety of GIA632 Across a Range of Doses in Participants With Moderate to Severe Cutaneous Lichen Planus", "status": "RECRUITING", "phase": "Phase 2", "lead_sponsor": "Novartis Pharmaceuticals", "conditions": [ "Cutaneous Lichen Planus" ], "sites": [ "Birmingham", "Fountain Valley", "Miami", "St. Petersburg", "Macon", "Indianapolis", "Overland Park", "Baton Rouge" ], "enrollment": 259, "start_date": "2026-09-29", "registry_url": "https://clinicaltrials.gov/study/NCT07775924" }, { "nct_id": "NCT07778498", "title": "A Phase I/II, First-in-Human Study to Evaluate TJ102 in Participants With Advanced or Metastatic Ovarian Cancer and Other Solid Tumors.", "status": "RECRUITING", "phase": "Phase 1/2", "lead_sponsor": "Phrontline Biopharma", "conditions": [ "Ovarian Cancer" ], "sites": [ "Los Angeles", "Orlando", "Lake Success", "Philadelphia", "Nashville", "Houston", "Irving", "Fairfax" ], "enrollment": 150, "start_date": "2026-09-29", "registry_url": "https://clinicaltrials.gov/study/NCT07778498" }, { "nct_id": "NCT07842393", "title": "A Study of IBI3042 in Healthy Adult Participants", "status": "NOT_YET_RECRUITING", "phase": "Phase 1", "lead_sponsor": "Fortvita Biologics (USA)Inc.", "conditions": [ "Healthy Volunteers (HV)" ], "sites": [ "Lenexa" ], "enrollment": 32, "start_date": "2026-09-29", "registry_url": "https://clinicaltrials.gov/study/NCT07842393" }, { "nct_id": "NCT07768189", "title": "A Study to Evaluate CRB-701 Compared to Investigator's Choice Therapy in Previously Treated Oropharyngeal Squamous Cell Carcinoma", "status": "RECRUITING", "phase": "Phase 3", "lead_sponsor": "Corbus Pharmaceuticals Inc.", "conditions": [ "Oropharyngeal Carcinoma (OPC)" ], "sites": [ "Huntsville", "Tucson", "Duarte", "Los Angeles", "Palo Alto", "San Diego", "San Francisco", "Colorado Springs" ], "enrollment": 260, "start_date": "2026-09-29", "registry_url": "https://clinicaltrials.gov/study/NCT07768189" }, { "nct_id": "NCT07029945", "title": "A Phase 1/2 Study of the Safety and Efficacy of BRX011 Oral Administration Once Daily in Subjects With Geographic Atrophy Secondary to Age-Related Macular Degeneration", "status": "RECRUITING", "phase": "Phase 1/2", "lead_sponsor": "Biojiva LLC", "conditions": [ "Geographic Atrophy" ], "sites": [ "Gilbert", "Phoenix", "Hattiesburg", "Reno", "Beachwood", "Cleveland", "Middleburg Heights", "Abilene" ], "enrollment": 152, "start_date": "2026-09-29", "registry_url": "https://clinicaltrials.gov/study/NCT07029945" }, { "nct_id": "NCT07857837", "title": "Study of Sulthiame (S-054502) in Participants With Renal Impairment and Matched Healthy Controls", "status": "NOT_YET_RECRUITING", "phase": "Phase 1", "lead_sponsor": "Shionogi", "conditions": [ "Renal Impairment" ], "sites": [ "Altamonte Springs", "Miami Lakes" ], "enrollment": 30, "start_date": "2026-09-29", "registry_url": "https://clinicaltrials.gov/study/NCT07857837" }, { "nct_id": "NCT07751991", "title": "A Study of CHM-029 in Participants With NPM1 Mutated, KMT2A or NUP98 Rearranged AML", "status": "RECRUITING", "phase": "Phase 1", "lead_sponsor": "Charm Therapeutics", "conditions": [ "AML (Acute Myeloid Leukemia)" ], "sites": [ "Duarte", "New Haven", "Grand Rapids" ], "enrollment": 40, "start_date": "2026-09-28", "registry_url": "https://clinicaltrials.gov/study/NCT07751991" }, { "nct_id": "NCT07839871", "title": "Study to Learn About a Respiratory Syncytial Virus Vaccine in Children at High Risk of RSV Disease", "status": "NOT_YET_RECRUITING", "phase": "Phase 3", "lead_sponsor": "Pfizer", "conditions": [ "Respiratory Syncytial Virus (RSV)" ], "sites": [ "South Euclid" ], "enrollment": 920, "start_date": "2026-09-28", "registry_url": "https://clinicaltrials.gov/study/NCT07839871" }, { "nct_id": "NCT07782970", "title": "A Study to Assess the Efficacy and Safety of GSK5784283 (Felcorekibart) in Participants With Chronic Rhinosinusitis With Nasal Polyps (CRSwNP)", "status": "RECRUITING", "phase": "Phase 3", "lead_sponsor": "GlaxoSmithKline", "conditions": [ "Nasal Polyps" ], "sites": [ "Los Angeles", "Tulsa" ], "enrollment": 218, "start_date": "2026-09-28", "registry_url": "https://clinicaltrials.gov/study/NCT07782970" }, { "nct_id": "NCT07441278", "title": "A Clinical Trial of NS-863 in Participants With Pulmonary Hypertension Associated With Interstitial Lung Disease (PH-ILD)", "status": "RECRUITING", "phase": "Phase 2", "lead_sponsor": "NS Pharma, Inc.", "conditions": [ "Pulmonary Hypertension Associated With Interstitial Lung Disease (PH-ILD)" ], "sites": [ "Knoxville" ], "enrollment": 177, "start_date": "2026-09-28", "registry_url": "https://clinicaltrials.gov/study/NCT07441278" }, { "nct_id": "NCT07858214", "title": "Measurement of Ocular Microtremor With the iTremor Device in a Diverse US Cohort", "status": "ENROLLING_BY_INVITATION", "phase": "Observational", "lead_sponsor": "Head Diagnostics", "conditions": [ "All Conditions", "All" ], "sites": [ "Atlanta", "Cambridge" ], "enrollment": 120, "start_date": "2026-09-28", "registry_url": "https://clinicaltrials.gov/study/NCT07858214" }, { "nct_id": "NCT07891780", "title": "Pharmacokinetics and Safety of a Single Dose of Epinephrine Nasal Spray in Paediatric Allergy Patients", "status": "NOT_YET_RECRUITING", "phase": "Phase 2", "lead_sponsor": "Hikma Pharmaceuticals USA Inc.", "conditions": [ "Epinephrine", "Hypersensitivity, Immediate", "Anaphylaxis" ], "sites": [ "Marlton", "Salt Lake City" ], "enrollment": 44, "start_date": "2026-09-28", "registry_url": "https://clinicaltrials.gov/study/NCT07891780" }, { "nct_id": "NCT07826429", "title": "Evaluation of the F&P Mask, US, 2026", "status": "RECRUITING", "phase": "Not applicable", "lead_sponsor": "Fisher and Paykel Healthcare", "conditions": [ "Chronic Respiratory Conditions", "Obstructive Sleep Apnea (OSA)" ], "sites": [ "St Louis" ], "enrollment": 45, "start_date": "2026-09-28", "registry_url": "https://clinicaltrials.gov/study/NCT07826429" }, { "nct_id": "NCT07799532", "title": "A Trial Investigating the Efficacy and Safety of NVG-291 in Subjects With Chronic Spinal Cord Injury", "status": "RECRUITING", "phase": "Phase 3", "lead_sponsor": "NervGen Pharma", "conditions": [ "Chronic Spinal Cord Injury" ], "sites": [ "Birmingham", "Pheonix", "Downey", "Englewood", "Stamford", "Washington D.C.", "Miami", "Atlanta" ], "enrollment": 150, "start_date": "2026-09-28", "registry_url": "https://clinicaltrials.gov/study/NCT07799532" }, { "nct_id": "NCT07725796", "title": "A Phase 1 Dose-escalation 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"2026-09-28", "registry_url": "https://clinicaltrials.gov/study/NCT07893093" }, { "nct_id": "NCT07898072", "title": "Safety and Efficacy of Weekly Testosterone Cypionate Auto-Injector in Men With Hypogonadism", "status": "RECRUITING", "phase": "Phase 3", "lead_sponsor": "Amneal Pharmaceuticals, LLC", "conditions": [ "Male Hypogonadism" ], "sites": [ "Santa Monica", "DeLand", "Miami Lakes", "Omaha", "Garden City", "New York", "Providence", "North Charleston" ], "enrollment": 190, "start_date": "2026-09-28", "registry_url": "https://clinicaltrials.gov/study/NCT07898072" }, { "nct_id": "NCT07622108", "title": "Treatment of Active Thyroid Eye Disease With MHB018A in a Randomized, Placebo-Controlled Study", "status": "RECRUITING", "phase": "Phase 3", "lead_sponsor": "Minghui Pharmaceutical (Hangzhou) Ltd", "conditions": [ "Thyroid Eye Disease, TED" ], "sites": [ "Coral Gables" ], "enrollment": 84, "start_date": "2026-09-28", "registry_url": "https://clinicaltrials.gov/study/NCT07622108" }, { "nct_id": "NCT07862608", "title": "Evaluation of the UltraTrac System as a Non-Invasive Monitor of Hemodynamic Parameters", "status": "NOT_YET_RECRUITING", "phase": "Observational", "lead_sponsor": "AcQumen Medical, Inc.", "conditions": [ "Hemodynamic Monitoring" ], "sites": [ "Riverside" ], "enrollment": 400, "start_date": "2026-09-27", "registry_url": "https://clinicaltrials.gov/study/NCT07862608" }, { "nct_id": "NCT07578363", "title": "An Investigation of FID 123472 Ophthalmic Solution to Vehicle for the Reduction of Ocular Redness in Adults", "status": "RECRUITING", "phase": "Phase 3", "lead_sponsor": "Alcon Research", "conditions": [ "Ocular Hyperemia" ], "sites": [ "Northbrook", "Garner", "Shelby", "Memphis", "Lynchburg" ], "enrollment": 178, "start_date": "2026-09-27", "registry_url": "https://clinicaltrials.gov/study/NCT07578363" }, { "nct_id": "NCT07142278", "title": "DUVAX: A Phase 1 Alzheimer's Vaccine Study Targeting Amyloid-Beta and Tau", "status": "RECRUITING", "phase": "Phase 1", "lead_sponsor": "Nuravax, Inc.", "conditions": [ "Alzheimer Disease", "Alzheimer Disease (AD)", "Preclinical Alzheimer's Disease" ], "sites": [ "Miami Lakes" ], "enrollment": 24, "start_date": "2026-09-25", "registry_url": "https://clinicaltrials.gov/study/NCT07142278" }, { "nct_id": "NCT07785830", "title": "A Clinical Trial to Evaluate the Effects of MK-4646 on Rosuvastatin in Healthy Participants (MK-4646-007)", "status": "NOT_YET_RECRUITING", "phase": "Phase 1", "lead_sponsor": "Merck Sharp & Dohme LLC", "conditions": [ "Healthy" ], "sites": [ "South Miami" ], "enrollment": 16, "start_date": "2026-09-25", "registry_url": "https://clinicaltrials.gov/study/NCT07785830" }, { "nct_id": "NCT07817875", "title": "Efficacy, Safety, and Pharmacokinetics of Tirzepatide (LY3298176) Once Weekly Versus Placebo in Pediatric Participants 6 to Less Than 12 Years of Age Who Have Obesity (ADVANCE-SURMOUNT-KIDS)", "status": "RECRUITING", "phase": "Phase 3", "lead_sponsor": "Eli Lilly and Company", "conditions": [ "Obesity" ], "sites": [ "Tucson", "Loma Linda", "Los Angeles", "Orange", "Oxnard", "Colorado Springs", "New Haven", "Orlando" ], "enrollment": 150, "start_date": "2026-09-25", "registry_url": "https://clinicaltrials.gov/study/NCT07817875" }, { "nct_id": "NCT07705607", "title": "A Clinical Trial of MK-8748 Compared to Aflibercept in Participants With Diabetic Macular Edema (MK-8748-005)", "status": "RECRUITING", "phase": "Phase 3", "lead_sponsor": "Merck Sharp & Dohme LLC", "conditions": [ "Diabetic Retinopathy", "Macular Edema" ], "sites": [ "Waterford", "Orlando", "St. Petersburg", "Winter Haven", "Carmel", "West Des Moines", "Hagerstown", "Liverpool" ], "enrollment": 1104, "start_date": "2026-09-25", "registry_url": "https://clinicaltrials.gov/study/NCT07705607" }, { "nct_id": "NCT07905105", "title": "A Study of CYT-1010 in Healthy Volunteers and Participants With Acute Pain After Third Molar Extraction", "status": "RECRUITING", "phase": "Phase 1/2", "lead_sponsor": "Cytogel Pharma, LLC", "conditions": [ "Acute Postoperative Pain", "Dental Pain" ], "sites": [ "Salt Lake City" ], "enrollment": 32, "start_date": "2026-09-25", "registry_url": "https://clinicaltrials.gov/study/NCT07905105" }, { "nct_id": "NCT07836998", "title": "A Study to Assess the Efficacy of an Experimental Mouthwash Used With a Marketed Whitening Toothpaste on Stain Build-up", "status": "RECRUITING", "phase": "Not applicable", "lead_sponsor": "HALEON", "conditions": [ "Tooth Discoloration" ], "sites": [ "Melbourne" ], "enrollment": 360, "start_date": "2026-09-25", "registry_url": "https://clinicaltrials.gov/study/NCT07836998" }, { "nct_id": "NCT07513285", "title": "ACX-362E [Ibezapolstat] for Oral Treatment of Recurrent Clostridioides Difficile Infection", "status": "RECRUITING", "phase": "Phase 2", "lead_sponsor": "Acurx Pharmaceuticals Inc.", "conditions": [ "Clostridium Difficile Infection Recurrence" ], "sites": [ "Sacramento", "Hamden", "Coral Gables", "Hialeah", "Miami Lakes", "Miami Springs", "Athens", "Idaho Falls" ], "enrollment": 20, "start_date": "2026-09-25", "registry_url": "https://clinicaltrials.gov/study/NCT07513285" }, { "nct_id": "NCT07820891", "title": "A Trial in Healthy Participants to Assess Drug Interaction Potential of BGB-43395", "status": "RECRUITING", "phase": "Phase 1", "lead_sponsor": "BeOne Medicines", "conditions": [ "Healthy Adult Participants" ], "sites": [ "Dallas" ], "enrollment": 24, "start_date": "2026-09-25", "registry_url": "https://clinicaltrials.gov/study/NCT07820891" }, { "nct_id": "NCT07752407", "title": "A Study to Evaluate the Efficacy and Safety of Vonoprazan 10 mg Compared to Placebo for Relief of Episodic Heartburn in Participants With Symptomatic Non-Erosive Gastroesophageal Reflux Disease Through 24 Weeks", "status": "RECRUITING", "phase": "Phase 3", "lead_sponsor": "Phathom Pharmaceuticals, Inc.", "conditions": [ "Symptomatic Non-erosive Gastroesophageal Reflux Disease" ], "sites": [ "Mentor" ], "enrollment": 500, "start_date": "2026-09-25", "registry_url": "https://clinicaltrials.gov/study/NCT07752407" }, { "nct_id": "NCT07607327", "title": "Forecasting Relapse Outcomes With AlloHeme-based Risk Detection in Post-Allo-HCT AML/MDS Patients (FORWARD)", "status": "ENROLLING_BY_INVITATION", "phase": "Observational", "lead_sponsor": "CareDx", "conditions": [ "AML (Acute Myelogenous Leukemia)", "MDS (Myelodysplastic Syndrome)", "CMML" ], "sites": [ "Brisbane", "San Francisco", "St Louis" ], "enrollment": 400, "start_date": "2026-09-24", "registry_url": "https://clinicaltrials.gov/study/NCT07607327" }, { "nct_id": "NCT07816666", "title": "Torvutatug Samrotecan With or Without Bevacizumab as Maintenance Treatment of Platinum-sensitive Relapsed Epithelial Ovarian Cancer", "status": "RECRUITING", "phase": "Phase 3", "lead_sponsor": "AstraZeneca", "conditions": [ "Platinum-sensitive Relapsed Epithelial Ovarian Cancer", "Platinum-sensitive Relapsed Fallopian Tube Cancer", "Platinum-sensitive Relapsed Primary Peritoneal Cancer" ], "sites": [ "Anchorage", "Miami", "Indianapolis", "Shreveport", "Columbia", "Ann Arbor", "Detroit", "Albany" ], "enrollment": 600, "start_date": "2026-09-24", "registry_url": "https://clinicaltrials.gov/study/NCT07816666" }, { "nct_id": "NCT07700979", "title": "Phase 3 Study of Cadonilimab Combined With Chemotherapy vs Chemotherapy in Combination With or Without Nivolumab for the 1L Treatment of Participants With HER2-negative, Previously Untreated, Unresectable or Metastatic Gastric/GEJ Adenocarcinoma", "status": "RECRUITING", "phase": "Phase 3", "lead_sponsor": "Akeso", "conditions": [ "Gastric / Gastroesophageal Junction Adenocarcinoma" ], "sites": [ "Phoenix", "Los Angeles", "Denver", "New Haven", "Boston", "Detroit", "New York", "Portland" ], "enrollment": 900, "start_date": "2026-09-24", "registry_url": "https://clinicaltrials.gov/study/NCT07700979" }, { "nct_id": "NCT07622121", "title": "Treatment of Chronic Thyroid Eye Disease With MHB018A", "status": "RECRUITING", "phase": "Phase 3", "lead_sponsor": "Minghui Pharmaceutical (Hangzhou) Ltd", "conditions": [ "Thyroid Eye Disease, TED" ], "sites": [ "Coral Gables" ], "enrollment": 135, "start_date": "2026-09-24", "registry_url": "https://clinicaltrials.gov/study/NCT07622121" }, { "nct_id": "NCT07718581", "title": "HMPL-A830 in Solid Tumors", "status": "RECRUITING", "phase": "Phase 1/2", "lead_sponsor": "Hutchmed", "conditions": [ "Solid Tumor, Adult" ], "sites": [ "Orange", "Coral Springs", "Plantation", "East Brunswick", "Nashville", "West Valley City" ], "enrollment": 147, "start_date": "2026-09-24", "registry_url": "https://clinicaltrials.gov/study/NCT07718581" }, { "nct_id": "NCT07735637", "title": "A Phase III, Multicentre Study to Evaluate Consolidation Treatment With AZD0120 Compared With ASCT, in Participants With Newly Diagnosed Multiple Myeloma Who Are Transplant Eligible (DURGA-6).", "status": "RECRUITING", "phase": "Phase 3", "lead_sponsor": "AstraZeneca", "conditions": [ "Newly Diagnosed Multiple Myeloma (NDMM)" ], "sites": [ "Gilbert", "Goodyear", "Phoenix", "Los Angeles", "Orange", "San Francisco", "Stanford", "Denver" ], "enrollment": 750, "start_date": "2026-09-24", "registry_url": "https://clinicaltrials.gov/study/NCT07735637" }, { "nct_id": "NCT07506863", "title": "A Study to Investigate the Efficacy, Pharmacokinetics, and Safety of Mitapivat in Pediatric Participants With Transfusion-Dependent Alpha- or Beta-Thalassemia (\u03b1- or \u03b2-TDT)", "status": "RECRUITING", "phase": "Phase 3", "lead_sponsor": "Agios Pharmaceuticals, Inc.", "conditions": [ "Transfusion-dependent Alpha-Thalassemia", "Transfusion-dependent Beta-Thalassemia" ], "sites": [ "Atlanta", "New York", "Philadelphia", "Dallas" ], "enrollment": 54, "start_date": "2026-09-24", "registry_url": "https://clinicaltrials.gov/study/NCT07506863" }, { "nct_id": "NCT07768735", "title": "UNITY DX Cornea Study", "status": "RECRUITING", "phase": "Observational", "lead_sponsor": "Alcon Research", "conditions": [ "Tomography" ], "sites": [ "Salt Lake City" ], "enrollment": 110, "start_date": "2026-09-24", "registry_url": "https://clinicaltrials.gov/study/NCT07768735" }, { "nct_id": "NCT07786207", "title": "Knee Cartilage Repair Registry", "status": "RECRUITING", "phase": "Observational", "lead_sponsor": "Smith & Nephew, Inc.", "conditions": [ "Knee Injuries", "Joint Surface Knee Lesions" ], "sites": [ "Parker", "Washington D.C.", "Indianapolis", "Bowling Green", "Oklahoma City", "DuBois" ], "enrollment": 1000, "start_date": "2026-09-23", "registry_url": "https://clinicaltrials.gov/study/NCT07786207" }, { "nct_id": "NCT07688239", "title": "The BANYAN Trial, an ALS MyMatch Trial Evaluating Safety, Biomarker Activity, and Microglial Activation of Nasal Foralumab", "status": "ENROLLING_BY_INVITATION", "phase": "Phase 2", "lead_sponsor": "Tiziana Life Sciences LTD", "conditions": [ "ALS (Amyotrophic Lateral Sclerosis)", "ALS - Amyotrophic Lateral Sclerosis", "ALS" ], "sites": [ "Davie", "Chicago", "Boston", "Minneapolis" ], "enrollment": 44, "start_date": "2026-09-23", "registry_url": "https://clinicaltrials.gov/study/NCT07688239" }, { "nct_id": "NCT07804277", "title": "Comparative Study of the Tomey FT-1000, and Goldmann Applanation Tonometer (GAT)", "status": "RECRUITING", "phase": "Observational", "lead_sponsor": "Tomey Corporation", "conditions": [ "Glaucoma" ], "sites": [ "Jacksonville" ], "enrollment": 30, "start_date": "2026-09-23", "registry_url": "https://clinicaltrials.gov/study/NCT07804277" }, { "nct_id": "NCT07813039", "title": "A Phase 1 Relative Bioavailability Study of a VX-581 Tablet Formulation", "status": "ACTIVE_NOT_RECRUITING", "phase": "Phase 1", "lead_sponsor": "Vertex Pharmaceuticals Incorporated", "conditions": [ "Cystic Fibrosis" ], "sites": [ "Tempe" ], "enrollment": 16, "start_date": "2026-09-23", "registry_url": "https://clinicaltrials.gov/study/NCT07813039" }, { "nct_id": "NCT07637071", "title": "Study to Evaluate Xtress\u00e9 Gummy Supplement in Men With Androgenic Alopecia", "status": "ENROLLING_BY_INVITATION", "phase": "Not applicable", "lead_sponsor": "Restore Biologics Holdings, Inc. dba Xtress\u00e9", "conditions": [ "Androgenic Alopecia", "Hair Loss/Baldness", "Hair Thinning" ], "sites": [ "Maitland", "Port Orange" ], "enrollment": 48, "start_date": "2026-09-23", "registry_url": "https://clinicaltrials.gov/study/NCT07637071" }, { "nct_id": "NCT06956014", "title": "Efficacy and Safety of VER-01 in the Treatment of Participants With Chronic Painful Lumbosacral Radiculopathy", "status": "RECRUITING", "phase": "Phase 3", "lead_sponsor": "Vertanical GmbH", "conditions": [ "Lumbosacral Radiculopathy" ], "sites": [ "Mobile", "Tempe", "Long Beach", "Bradenton", "Jacksonville", "Miami", "Orlando", "Pembroke Pines" ], "enrollment": 810, "start_date": "2026-09-22", "registry_url": "https://clinicaltrials.gov/study/NCT06956014" }, { "nct_id": "NCT07756645", "title": "A Study to Assess Intravenous ABBV-1480 Combined With Chemotherapy Versus Pembrolizumab Combined With Chemotherapy for the First Line Treatment of Locally Advanced/Metastatic Non-Small Cell Lung Cancer in Adult Participants", "status": "RECRUITING", "phase": "Phase 3", "lead_sponsor": "AbbVie", "conditions": [ "Non-Small Cell Lung Cancer" ], "sites": [ "Fort Wayne" ], "enrollment": 940, "start_date": "2026-09-22", "registry_url": "https://clinicaltrials.gov/study/NCT07756645" }, { "nct_id": "NCT07845071", "title": "An Open-Label, Safety and Efficacy Study of Cebranopadol in Participants With Acute Pain With Surgical or Non-Surgical Origin", "status": "RECRUITING", "phase": "Phase 3", "lead_sponsor": "Adneuris Therapeutics, Inc.", "conditions": [ "Pain" ], "sites": [ "Phoenix", "Riverside", "Longmont", "Savannah", "O'Fallon", "Annapolis", "Oradell", "Tulsa" ], "enrollment": 160, "start_date": "2026-09-22", "registry_url": "https://clinicaltrials.gov/study/NCT07845071" }, { "nct_id": "NCT07873463", "title": "Flutemetamol F 18 Injection Formulation Comparison", "status": "NOT_YET_RECRUITING", "phase": "Phase 2", "lead_sponsor": "GE Healthcare", "conditions": [ "Cognitive Dysfunction" ], "sites": [ "Aventura", "Merritt Island", "Miami", "Winter Park", "Gainesville" ], "enrollment": 20, "start_date": "2026-09-22", "registry_url": "https://clinicaltrials.gov/study/NCT07873463" }, { "nct_id": "NCT07363473", "title": "JOURNEY LVAD: JOURNEY Left Ventricular Assist Device", "status": "ACTIVE_NOT_RECRUITING", "phase": "Not applicable", "lead_sponsor": "JC Medical, Inc., an affiliate of Edwards Lifesciences LLC", "conditions": [ "Aortic Valve Regurgitation", "Aortic Valve Disease Mixed", "Aortic Insufficiency" ], "sites": [ "Boston", "Nashville" ], "enrollment": 50, "start_date": "2026-09-22", "registry_url": "https://clinicaltrials.gov/study/NCT07363473" }, { "nct_id": "NCT07684313", "title": "TRIFORMIS RESILIA Real-world Study Assessing Safety and Performance (TRIBLAZE Study)", "status": "RECRUITING", "phase": "Observational", "lead_sponsor": "Edwards Lifesciences", "conditions": [ "Heart Valve Diseases", "Heart Diseases", "Cardiovascular Diseases", "Tricuspid Valve Disease" ], "sites": [ "Carmel" ], "enrollment": 75, "start_date": "2026-09-22", "registry_url": "https://clinicaltrials.gov/study/NCT07684313" }, { "nct_id": "NCT07808073", "title": "A Study of LY4329090 in Participants With Obesity or Overweight Who Are Otherwise Healthy", "status": "RECRUITING", "phase": "Phase 1", "lead_sponsor": "Eli Lilly and Company", "conditions": [ "Obesity", "Overweight" ], "sites": [ "Daytona Beach", "Dallas" ], "enrollment": 184, "start_date": "2026-09-22", "registry_url": "https://clinicaltrials.gov/study/NCT07808073" }, { "nct_id": "NCT07668414", "title": "A Research Study Investigating How Well the Medicine Zenagamtide Helps People With Excess Body Weight Lose Weight Compared to Semaglutide", "status": "RECRUITING", "phase": "Phase 3", "lead_sponsor": "Novo Nordisk A/S", "conditions": [ "Overweight", "Obesity" ], "sites": [ "Lancaster", "Palm Springs", "Pomona", "San Diego", "Washington D.C.", "Hollywood", "Jacksonville", "Miami" ], "enrollment": 650, "start_date": "2026-09-22", "registry_url": "https://clinicaltrials.gov/study/NCT07668414" }, { "nct_id": "NCT07811999", "title": "Comparing the Extent to Which Romosozumab (AMG 785) is Made Available in the Body When Administered as a Single SC Injection or as 2 SC Injections", "status": "RECRUITING", "phase": "Phase 1", "lead_sponsor": "Amgen", "conditions": [ "Healthy Participants" ], "sites": [ "Miami" ], "enrollment": 308, "start_date": "2026-09-22", "registry_url": "https://clinicaltrials.gov/study/NCT07811999" }, { "nct_id": "NCT07853131", "title": "Study to Assess the Plasma Concentration of Rilzabrutinib Given as a Tablet to Adult Participants With Severe Renal Impairment Compared to Matched Participants With Normal Renal Function", "status": "RECRUITING", "phase": "Phase 1", "lead_sponsor": "Sanofi", "conditions": [ "Renal Impairment", "Healthy Volunteers" ], "sites": [ "Hialeah" ], "enrollment": 16, "start_date": "2026-09-22", "registry_url": "https://clinicaltrials.gov/study/NCT07853131" }, { "nct_id": "NCT07866131", "title": "Observational Assessment of Skin Appearance Changes During PRX S Cosmetic Treatment in Participants With Acne-Prone Skin", "status": "RECRUITING", "phase": "Not applicable", "lead_sponsor": "WiQo S.p.A.", "conditions": [ "Acne-prone Skin", "Skin Disease" ], "sites": [ "Leawood", "Tulsa" ], "enrollment": 30, "start_date": "2026-09-21", "registry_url": "https://clinicaltrials.gov/study/NCT07866131" }, { "nct_id": "NCT07859852", "title": "Evaluation of Diagnostic Accuracy and Clinical Performance of the UllCORE Bloodstream Infection (BSI) Test", "status": "RECRUITING", "phase": "Observational", "lead_sponsor": "Deepull Diagnostics S.L.", "conditions": [ "Blood Stream Infection", "Blood Stream Infections", "Sepsis", "Fungemia" ], "sites": [ "Orange", "Tampa", "Baltimore", "Boston", "Novi", "St Louis", "Cleveland", "Danville" ], "enrollment": 1500, "start_date": "2026-09-21", "registry_url": "https://clinicaltrials.gov/study/NCT07859852" }, { "nct_id": "NCT07819435", "title": "Phase 2/3 Efficacy and Safety of PP405 in Adult Males", "status": "RECRUITING", "phase": "Phase 2/3", "lead_sponsor": "Pelage Pharmaceuticals, Inc.", "conditions": [ "Androgenetic Alopecia" ], "sites": [ "Birmingham", "Fort Smith", "Hot Springs", "Rogers", "Fountain Valley", "Manhattan Beach", "Northridge", "Sacramento" ], "enrollment": 600, "start_date": "2026-09-21", "registry_url": "https://clinicaltrials.gov/study/NCT07819435" }, { "nct_id": "NCT07831317", "title": "Multi-strain Probiotic Supplement for Digestive Comfort and Well-being in Healthy Women", "status": "RECRUITING", "phase": "Not applicable", "lead_sponsor": "Daily Nouri", "conditions": [ "Gastrointestinal Discomfort", "Bloating" ], "sites": [ "San Francisco" ], "enrollment": 160, "start_date": "2026-09-19", "registry_url": "https://clinicaltrials.gov/study/NCT07831317" }, { "nct_id": "NCT07860905", "title": "A Study to Test the Repeatability and Reproducibility in Rod Intercept Time Within the AdaptDx Pro in Healthy Subjects With Normal Vision (FlashForward)", "status": "RECRUITING", "phase": "Observational", "lead_sponsor": "AdaptDx, Inc.", "conditions": [ "No Disease" ], "sites": [ "Silverdale" ], "enrollment": 16, "start_date": "2026-09-18", "registry_url": "https://clinicaltrials.gov/study/NCT07860905" }, { "nct_id": "NCT07814404", "title": "A Study to Assess the Mass Balance, Pharmacokinetics, and Metabolite Profiles of a Single Oral Dose of [14C]-INCB161734 in Healthy Male Participants", "status": "ACTIVE_NOT_RECRUITING", "phase": "Phase 1", "lead_sponsor": "Incyte Corporation", "conditions": [ "Healthy Participants" ], "sites": [ "Lincoln" ], "enrollment": 10, "start_date": "2026-09-18", "registry_url": "https://clinicaltrials.gov/study/NCT07814404" }, { "nct_id": "NCT07776691", "title": "A Study of Raludotatug Deruxtecan With or Without Bevacizumab as First-Line Maintenance Treatment in Non-HRD-Positive Advanced Ovarian Cancer (MK-5909-006, (ENGOT-ov102/GOG-3141/ REJOICE-Ovarian 04)", "status": "RECRUITING", "phase": "Phase 3", "lead_sponsor": "Merck Sharp & Dohme LLC", "conditions": [ "Ovarian Cancer", "Ovarian Neoplasms", "Peritoneal Cancer", "Fallopian Tube Cancer" ], "sites": [ "Washington D.C.", "Burlington", "Eugene", "Austin", "Fort Worth", "Tyler" ], "enrollment": 802, "start_date": "2026-09-18", "registry_url": "https://clinicaltrials.gov/study/NCT07776691" }, { "nct_id": "NCT07830719", "title": "Dose-finding Study of YMI024 to Assess Efficacy, Safety, and Tolerability in Adults With Stable Coronary Artery Disease and Elevated hsCRP", "status": "RECRUITING", "phase": "Phase 2", "lead_sponsor": "Novartis Pharmaceuticals", "conditions": [ "Coronary Artery Disease" ], "sites": [ "Fairhope", "Foley", "Los Angeles", "Coral Gables", "Wichita", "Ft. Washington", "Oxon Hill", "Amarillo" ], "enrollment": 180, "start_date": "2026-09-18", "registry_url": "https://clinicaltrials.gov/study/NCT07830719" }, { "nct_id": "NCT07683754", "title": "T-DXd Based Therapy Followed by Endocrine Therapy Plus Dual HER2 Blockade in First-line HER2+/ HR+ Metastatic Breast Cancer and Retreatment With T-DXd", "status": "RECRUITING", "phase": "Phase 3", "lead_sponsor": "Daiichi Sankyo", "conditions": [ "Advanced Breast Cancer", "Metastatic Breast Cancer", "HER2 Positive", "HR Positive" ], "sites": [ "Columbia", "Las Vegas", "Nashville", "El Paso", "New Braunfels" ], "enrollment": 200, "start_date": "2026-09-18", "registry_url": "https://clinicaltrials.gov/study/NCT07683754" }, { "nct_id": "NCT07840157", "title": "A Mixed-Methods Exploratory Pilot Study of the Investigational MYNERVA Leia Sensory Prosthesis in U.S. Adults With Peripheral Neuropathy", "status": "NOT_YET_RECRUITING", "phase": "Not applicable", "lead_sponsor": "Mynerva Inc.", "conditions": [ "Peripheral Neuropathy" ], "sites": [ "Ocean Springs" ], "enrollment": 100, "start_date": "2026-09-18", "registry_url": "https://clinicaltrials.gov/study/NCT07840157" }, { "nct_id": "NCT07546253", "title": "Post-Market Real-World Evidence Registry for the NeuroOne OneRF\u00ae Ablation System for Epilepsy", "status": "RECRUITING", "phase": "Observational", "lead_sponsor": "NeuroOne Medical Technologies Corporation", "conditions": [ "Drug Resistant Epilepsy", "Refractory Epilepsy" ], "sites": [ "Miami", "Livingston", "New Brunswick" ], "enrollment": 100, "start_date": "2026-09-18", "registry_url": "https://clinicaltrials.gov/study/NCT07546253" }, { "nct_id": "NCT07760506", "title": "The Effects of Quercefit\u00ae and Ubiqsome\u2122 in Mitigating Inflammation and Promoting Metabolic Health", "status": "RECRUITING", "phase": "Not applicable", "lead_sponsor": "Applied Science & Performance Institute", "conditions": [ "Healthy Aging", "Inflammaging", "Metabolic Health", "Quercetin" ], "sites": [ "Tampa" ], "enrollment": 60, "start_date": "2026-09-18", "registry_url": "https://clinicaltrials.gov/study/NCT07760506" }, { "nct_id": "NCT07867080", "title": "A Phase 3 Trial for Intravitreal Injection of 4D-150 in Adults With Diabetic Macular Edema (DME).", "status": "RECRUITING", "phase": "Phase 3", "lead_sponsor": "4D Molecular Therapeutics", "conditions": [ "Diabetic Macular Edema (DME)" ], "sites": [ "Scottsdale", "Encino", "Fullerton", "Sacramento", "San Diego", "San Mateo", "Walnut Creek", "Aurora" ], "enrollment": 514, "start_date": "2026-09-18", "registry_url": "https://clinicaltrials.gov/study/NCT07867080" }, { "nct_id": "NCT07695389", "title": "Efficacy of a Novel Cellular, Acellular, Matrix-like Product (CAMP) Plus Standard of Care Versus Standard of Care Alone in the Management of Post-Mohs Micrographic Surgery Defects.", "status": "RECRUITING", "phase": "Not applicable", "lead_sponsor": "BioLab Holdings", "conditions": [ "Mohs Micrographic Surgery", "Cutaneous Malignancy", "Mohs Surgical Defect" ], "sites": [ "Tulsa" ], "enrollment": 160, "start_date": "2026-09-18", "registry_url": "https://clinicaltrials.gov/study/NCT07695389" }, { "nct_id": "NCT07287436", "title": "Elite AF IDE Trial (Elite AF)", "status": "RECRUITING", "phase": "Not applicable", "lead_sponsor": "Boston Scientific Corporation", "conditions": [ "Atrial Fibrillation (AF)", "Stroke" ], "sites": [ "Jonesboro", "Charlotte" ], "enrollment": 400, "start_date": "2026-09-18", "registry_url": "https://clinicaltrials.gov/study/NCT07287436" }, { "nct_id": "NCT07371429", "title": "A Study in Pediatric Participants Aged \u22652 to <12 Years With a Suspected or Confirmed Bacterial Infection or Receiving Prophylaxis Antibiotics", "status": "NOT_YET_RECRUITING", "phase": "Phase 1", "lead_sponsor": "GlaxoSmithKline", "conditions": [ "Urinary Tract Infections" ], "sites": [ "Orange", "Shreveport", "Baltimore", "St Louis" ], "enrollment": 25, "start_date": "2026-09-18", "registry_url": "https://clinicaltrials.gov/study/NCT07371429" }, { "nct_id": "NCT07723963", "title": "A Study to Evaluate the Safety and Efficacy of JZP926 Capsule for the Treatment of Juvenile Myoclonic Epilepsy", "status": "RECRUITING", "phase": "Phase 2/3", "lead_sponsor": "Jazz Pharmaceuticals", "conditions": [ "Juvenile Myoclonic Epilepsy" ], "sites": [ "Phoenix", "Sacramento", "New Haven", "Tampa", "Atlanta", "Savannah", "Honolulu", "Boise" ], "enrollment": 260, "start_date": "2026-09-18", "registry_url": "https://clinicaltrials.gov/study/NCT07723963" }, { "nct_id": "NCT07701941", "title": "A Study of Patritumab Deruxtecan (HER3-DXd) in Combination With Trastuzumab Deruxtecan (T-DXd) in Participants With HR-Positive, HER2-Low or HER2-Ultralow Unresectable or Metastatic Breast Cancer", "status": "RECRUITING", "phase": "Phase 1/2", "lead_sponsor": "Daiichi Sankyo", "conditions": [ "Hormone Receptor Positive", "HER2-low or HER2-ultralow", "Unresectable or Metastatic Breast Cancer" ], "sites": [ "Los Angeles", "Stanford", "Aurora", "New Haven", "Boston", "New York", "Portland", "Memphis" ], "enrollment": 220, "start_date": "2026-09-17", "registry_url": "https://clinicaltrials.gov/study/NCT07701941" }, { "nct_id": "NCT07807995", "title": "A Phase 3 Open-Label Study of Long-term Treatment With Povetacicept in Adults With Immunoglobulin A Nephropathy", "status": "ENROLLING_BY_INVITATION", "phase": "Phase 3", "lead_sponsor": "Vertex Pharmaceuticals Incorporated", "conditions": [ "Immunoglobulin A Nephropathy" ], "sites": [ "Arvada", "Orlando", "Idaho Falls", "Houston" ], "enrollment": 605, "start_date": "2026-09-17", "registry_url": "https://clinicaltrials.gov/study/NCT07807995" }, { "nct_id": "NCT07811362", "title": "CRPS-RISE Outcomes Registry", "status": "RECRUITING", "phase": "Observational", "lead_sponsor": "Ambros Therapeutics, Inc.", "conditions": [ "Complex Regional Pain Syndrome I (CRPS I)" ], "sites": [ "Durham" ], "enrollment": 270, "start_date": "2026-09-17", "registry_url": "https://clinicaltrials.gov/study/NCT07811362" }, { "nct_id": "NCT07828860", "title": "Safety and Efficacy of Soquelitinib in Adults With Hidradenitis Suppurativa", "status": "RECRUITING", "phase": "Phase 1", "lead_sponsor": "Corvus Pharmaceuticals, Inc.", "conditions": [ "Hidradenitis Suppurativa (HS)" ], "sites": [ "West Lafayette", "Bowling Green", "Owensboro", "Boston", "New York", "The Bronx", "Fargo", "Mayfield Heights" ], "enrollment": 25, "start_date": "2026-09-17", "registry_url": "https://clinicaltrials.gov/study/NCT07828860" }, { "nct_id": "NCT07819110", "title": "Radicle HealthTM VIP: A Study Assessing the Impact of Health and Wellness Products on Metabolic Health and Related Health Outcomes", "status": "NOT_YET_RECRUITING", "phase": "Not applicable", "lead_sponsor": "Radicle Science", "conditions": [ "Metabolic Health" ], "sites": [ "Del Mar" ], "enrollment": 220, "start_date": "2026-09-17", "registry_url": "https://clinicaltrials.gov/study/NCT07819110" }, { "nct_id": "NCT07835997", "title": "Radicle Relaxation\u2122 CIX: A Study Assessing the Impact of Health and Wellness Products on Stress and Related Health Outcomes", "status": "NOT_YET_RECRUITING", "phase": "Not applicable", "lead_sponsor": "Radicle Science", "conditions": [ "Stress" ], "sites": [ "Del Mar" ], "enrollment": 550, "start_date": "2026-09-17", "registry_url": "https://clinicaltrials.gov/study/NCT07835997" }, { "nct_id": "NCT07540988", "title": "FIBRONEER-ACT: A Study to Test Whether Nerandomilast Helps People With Fibrosing Interstitial Lung Disease at Risk for Disease Progression", "status": "RECRUITING", "phase": "Phase 3", "lead_sponsor": "Boehringer Ingelheim", "conditions": [ "Interstitial Lung Diseases" ], "sites": [ "Birmingham", "Los Angeles", "Newport Beach", "New Haven", "Kissimmee", "Lakeland", "Loxahatchee Groves", "Naples" ], "enrollment": 466, "start_date": "2026-09-17", "registry_url": "https://clinicaltrials.gov/study/NCT07540988" }, { "nct_id": "NCT07823608", "title": "A Study to Learn About the Monthly Dosing Study Medicine Called Berobenatide in Adults With Breathing Problems During Sleep and Overweight or Obesity Who Use a Breathing Machine (PAP) (VESPER-OSA 1)", "status": "RECRUITING", "phase": "Phase 3", "lead_sponsor": "Pfizer", "conditions": [ "Apnea", "Sleep Disorders", "Overweight and/or Obesity" ], "sites": [ "Cullman", "Riverside", "Bradenton", "Maplewood", "Dallas", "Tomball" ], "enrollment": 258, "start_date": "2026-09-17", "registry_url": "https://clinicaltrials.gov/study/NCT07823608" }, { "nct_id": "NCT07829406", "title": "A Study to See How Safe a New Medicine (NNC0642-1895) is in Healthy People", "status": "RECRUITING", "phase": "Phase 1", "lead_sponsor": "Novo Nordisk A/S", "conditions": [ "Healthy Volunteers" ], "sites": [ "Salt Lake City" ], "enrollment": 148, "start_date": "2026-09-17", "registry_url": "https://clinicaltrials.gov/study/NCT07829406" }, { "nct_id": "NCT07832292", "title": "A Study of JNJ-101556143 in Participants With Metastatic Prostate Cancer", "status": "RECRUITING", "phase": "Phase 2", "lead_sponsor": "Janssen Research & Development, LLC", "conditions": [ "Prostatic Neoplasms" ], "sites": [ "Lafayette", "Plymouth", "Syracuse", "Germantown" ], "enrollment": 100, "start_date": "2026-09-16", "registry_url": "https://clinicaltrials.gov/study/NCT07832292" }, { "nct_id": "NCT07817251", "title": "Research Study on How People With Type 2 Diabetes Tolerate Switching From Semaglutide to Cagrisema", "status": "RECRUITING", "phase": "Phase 3", "lead_sponsor": "Novo Nordisk A/S", "conditions": [ "Diabetes Mellitus, Type 2" ], "sites": [ "Gilbert", "Fountain Valley", "Glendora", "La Jolla", "Los Angeles", "Northridge", "Pomona", "Sacramento" ], "enrollment": 210, "start_date": "2026-09-16", "registry_url": "https://clinicaltrials.gov/study/NCT07817251" }, { "nct_id": "NCT07793409", "title": "A Study to Evaluate the Long-term Safety and Efficacy of Lunsekimig in Adult Participants With Chronic Obstructive Pulmonary Disease (COPD)", "status": "ENROLLING_BY_INVITATION", "phase": "Phase 3", "lead_sponsor": "Sanofi", "conditions": [ "Chronic Obstructive Pulmonary Disease" ], "sites": [ "Newport Beach", "Boynton Beach", "Miami Lakes", "Tampa" ], "enrollment": 1508, "start_date": "2026-09-16", "registry_url": "https://clinicaltrials.gov/study/NCT07793409" }, { "nct_id": "NCT07723703", "title": "Phase 1 Open-label Study of AMX-883 Alone in Participants With AML and High-risk MDS and in Combination in Participants With AML", "status": "RECRUITING", "phase": "Phase 1", "lead_sponsor": "Amphista Therapeutics Ltd", "conditions": [ "Acute Myeloid Leukaemia", "High Risk Myelodysplastic Syndrome" ], "sites": [ "Fairfax" ], "enrollment": 54, "start_date": "2026-09-16", "registry_url": "https://clinicaltrials.gov/study/NCT07723703" }, { "nct_id": "NCT07851025", "title": "Torvutatug Samrotecan Plus Bevacizumab as First-line Maintenance in Homologous Recombination Deficiency (HRD) Negative Advanced Epithelial Ovarian Cancer", "status": "RECRUITING", "phase": "Phase 3", "lead_sponsor": "AstraZeneca", "conditions": [ "Epithelial Ovarian Cancer" ], "sites": [ "Tampa", "Baltimore", "Billings", "Cleveland" ], "enrollment": 950, "start_date": "2026-09-16", "registry_url": "https://clinicaltrials.gov/study/NCT07851025" }, { "nct_id": "NCT07465289", "title": "A Study to Evaluate The Long-Term Safety And Efficacy of Rozanolixizumab in Adult Participants With Ocular Myasthenia Gravis", "status": "RECRUITING", "phase": "Phase 3", "lead_sponsor": "UCB Biopharma SRL", "conditions": [ "Ocular Myasthenia Gravis" ], "sites": [ "Columbus" ], "enrollment": 100, "start_date": "2026-09-16", "registry_url": "https://clinicaltrials.gov/study/NCT07465289" }, { "nct_id": "NCT07587021", "title": "Study of YOLT-203 in Children and Adults With Primary Hyperoxaluria Type 1 (PH1)", "status": "RECRUITING", "phase": "Phase 2", "lead_sponsor": "YolTech Therapeutics Co., Ltd", "conditions": [ "Primary Hyperoxaluria Type 1", "PH1" ], "sites": [ "Birmingham", "Aurora", "St Louis", "Philadelphia" ], "enrollment": 36, "start_date": "2026-09-16", "registry_url": "https://clinicaltrials.gov/study/NCT07587021" }, { "nct_id": "NCT07777133", "title": "A Study to Evaluate the Metabolism, the Routes and Extent of Elimination, and Drug Levels of [14C]Navlimetostat (BMS-986504) in Healthy Female Participants", "status": "NOT_YET_RECRUITING", "phase": "Phase 1", "lead_sponsor": "Bristol-Myers Squibb", "conditions": [ "Healthy Female Participants" ], "sites": [ "Madison" ], "enrollment": 6, "start_date": "2026-09-16", "registry_url": "https://clinicaltrials.gov/study/NCT07777133" }, { "nct_id": "NCT07818915", "title": "A Study to Investigate Pharmacokinetics (PK), Safety, and Tolerability of VH4367310 in Healthy Adult Participants", "status": "RECRUITING", "phase": "Phase 1", "lead_sponsor": "ViiV Healthcare", "conditions": [ "HIV Infections" ], "sites": [ "Glendale", "Baltimore" ], "enrollment": 112, "start_date": "2026-09-15", "registry_url": "https://clinicaltrials.gov/study/NCT07818915" }, { "nct_id": "NCT07711002", "title": "Saruparib in Combination With Physician's Choice of ARPI in Patients With mHSPC Previously Treated With Docetaxel or 177Lu-PSMA Therapy Without Disease Progression and PSA \u2265 0.2 ng/mL (EvoPAR-PR05)", "status": "RECRUITING", "phase": "Phase 3", "lead_sponsor": "AstraZeneca", "conditions": [ "Metastatic Hormone-Sensitive Prostate Cancer (mHSPC)" ], "sites": [ "Hot Springs", "Springdale", "Beverly Hills", "Los Alamitos", "Los Angeles", "San Diego", "Margate", "Miami" ], "enrollment": 1330, "start_date": "2026-09-15", "registry_url": "https://clinicaltrials.gov/study/NCT07711002" }, { "nct_id": "NCT07801066", "title": "Testing Healthy Participants for Drowsiness After Single Dosing of Two Different Doses of Muscle Relaxer", "status": "NOT_YET_RECRUITING", "phase": "Phase 4", "lead_sponsor": "Primus Pharmaceuticals", "conditions": [ "Healthy Participants" ], "sites": [ "Columbus" ], "enrollment": 20, "start_date": "2026-09-15", "registry_url": "https://clinicaltrials.gov/study/NCT07801066" }, { "nct_id": "NCT07648264", "title": "Single-arm Study of IgPro20 in Adults With Secondary Immune Deficiencies Due to Hematologic Malignancies Treated With B-cell Targeting Chimeric Antigen Receptor T-cell and T-cell Redirecting Therapies", "status": "RECRUITING", "phase": "Phase 3", "lead_sponsor": "CSL Behring", "conditions": [ "Secondary Immune Deficiency" ], "sites": [ "Orange", "Denver", "Coral Springs", "Jacksonville", "Lafayette", "Baltimore", "Bethesda", "Hackensack" ], "enrollment": 63, "start_date": "2026-09-15", "registry_url": "https://clinicaltrials.gov/study/NCT07648264" }, { "nct_id": "NCT07857161", "title": "Positron Emission Tomography/Computed Tomography (PECT/CT) Double-Scanning Study", "status": "RECRUITING", "phase": "Observational", "lead_sponsor": "GE Healthcare", "conditions": [ "PET/CT" ], "sites": [ "Stanford" ], "enrollment": 60, "start_date": "2026-09-15", "registry_url": "https://clinicaltrials.gov/study/NCT07857161" }, { "nct_id": "NCT07444593", "title": "Transverse Tibial Bone Transport (TTT) in the Management of Chronic Diabetic Lower Extremity Wounds", "status": "RECRUITING", "phase": "Not applicable", "lead_sponsor": "Biodynamik, Inc", "conditions": [ "Diabetic Foot Ulcer", "Chronic Ulcers of the Lower Limb" ], "sites": [ "Jacksonville" ], "enrollment": 100, "start_date": "2026-09-15", "registry_url": "https://clinicaltrials.gov/study/NCT07444593" }, { "nct_id": "NCT07808060", "title": "A Study of Eloralintide (LY3841136) in Female Participants With Obesity or Overweight", "status": "RECRUITING", "phase": "Phase 1", "lead_sponsor": "Eli Lilly and Company", "conditions": [ "Obesity", "Overweight" ], "sites": [ "Daytona Beach", "Dallas" ], "enrollment": 34, "start_date": "2026-09-15", "registry_url": "https://clinicaltrials.gov/study/NCT07808060" }, { "nct_id": "NCT07218185", "title": "Cryo-FIRST: Effectiveness of INTERCEPT Fibrinogen Complex (IFC) for Trauma-Associated Hemorrhage", "status": "ENROLLING_BY_INVITATION", "phase": "Observational", "lead_sponsor": "Cerus Corporation", "conditions": [ "Hypofibrinogenemia", "Hemorrhage", "Trauma Associated Hemorrhage", "Hemorrhagic Shock" ], "sites": [ "Aurora", "Miami", "Baltimore", "St Louis" ], "enrollment": 320, "start_date": "2026-09-15", "registry_url": "https://clinicaltrials.gov/study/NCT07218185" }, { "nct_id": "NCT07803588", "title": "A Study to Test the AdaptDx Pro Agreement in Rod Intercept Time With the AdaptDx in Healthy Subjects With Normal Vision (FlashBack)", "status": "RECRUITING", "phase": "Observational", "lead_sponsor": "AdaptDx, Inc.", "conditions": [ "Healthy Adult Participants" ], "sites": [ "San Diego" ], "enrollment": 24, "start_date": "2026-09-15", "registry_url": "https://clinicaltrials.gov/study/NCT07803588" }, { "nct_id": "NCT07819370", "title": "Enamel Lesion Detection With New DX Tool", "status": "NOT_YET_RECRUITING", "phase": "Phase 4", "lead_sponsor": "Colgate Palmolive", "conditions": [ "Enamel Lesions", "Caries" ], "sites": [ "Lithonia" ], "enrollment": 5, "start_date": "2026-09-15", "registry_url": "https://clinicaltrials.gov/study/NCT07819370" }, { "nct_id": "NCT07799207", "title": "Effects of Continuous Yogurt Intake on Immunomodulatory Function and Subjective Health Status in Healthy U.S. Adults", "status": "RECRUITING", "phase": "Not applicable", "lead_sponsor": "Meiji Co., Ltd.", "conditions": [ "Immune Function" ], "sites": [ "Chicago" ], "enrollment": 118, "start_date": "2026-09-14", "registry_url": "https://clinicaltrials.gov/study/NCT07799207" }, { "nct_id": "NCT07738107", "title": "ATR 1072 in Participants With PRKAG2 Syndrome", "status": "RECRUITING", "phase": "Phase 1/2", "lead_sponsor": "Atrium Therapeutics", "conditions": [ "Cardiac Glycogenosis", "Cardiomyopathy", "Hypertrophic", "Wolff-Parkinson-White Syndrome" ], "sites": [ "Kansas City" ], "enrollment": 37, "start_date": "2026-09-14", "registry_url": "https://clinicaltrials.gov/study/NCT07738107" }, { "nct_id": "NCT07823465", "title": "RNS System for Drug-Resistant Focal Epilepsy in Adolescents: A Real-World Study", "status": "ENROLLING_BY_INVITATION", "phase": "Observational", "lead_sponsor": "NeuroPace", "conditions": [ "Focal Epilepsy", "Drug-resistant Focal Epilepsy" ], "sites": [ "Waltham" ], "enrollment": 100, "start_date": "2026-09-14", "registry_url": "https://clinicaltrials.gov/study/NCT07823465" }, { "nct_id": "NCT07782229", "title": "Appetite and Cognition Response to a Breakfast Cereal", "status": "RECRUITING", "phase": "Not applicable", "lead_sponsor": "General Mills", "conditions": [ "Cognition" ], "sites": [ "Minneapolis" ], "enrollment": 184, "start_date": "2026-09-14", "registry_url": "https://clinicaltrials.gov/study/NCT07782229" }, { "nct_id": "NCT07675265", "title": "Observational, Non-interventional Biomarker and Endotyping Study", "status": "RECRUITING", "phase": "Observational", "lead_sponsor": "Prenosis, Inc.", "conditions": [ "ARDS (Acute Respiratory Distress Syndrome)" ], "sites": [ "Urbana" ], "enrollment": 1200, "start_date": "2026-09-14", "registry_url": "https://clinicaltrials.gov/study/NCT07675265" }, { "nct_id": "NCT07789639", "title": "A Clinical Study to Evaluate the Efficacy and SPF of Two Test Materials According to an Adaptation of the Guidelines of the FDA Sunscreen Drug Products for Over-the-Counter Human Use", "status": "RECRUITING", "phase": "Phase 4", "lead_sponsor": "Good Molecules, LLC", "conditions": [ "Epidermis", "Ultraviolet Exposure" ], "sites": [ "Winston-Salem" ], "enrollment": 60, "start_date": "2026-09-14", "registry_url": "https://clinicaltrials.gov/study/NCT07789639" }, { "nct_id": "NCT07807956", "title": "A Study to Assess Adverse Events, Change in Disease Activity and How Intravenous ABBV-253 Moves Through the Body in Adult Participants With Advanced Solid Tumors", "status": "RECRUITING", "phase": "Phase 1", "lead_sponsor": "AbbVie", "conditions": [ "Advanced Solid Tumors", "Non-Small Cell Lung Cancer", "Colorectal Cancer", "Pancreatic Ductal Adenocarcinoma" ], "sites": [ "Grand Rapids", "Huntersville", "Irving" ], "enrollment": 130, "start_date": "2026-09-14", "registry_url": "https://clinicaltrials.gov/study/NCT07807956" }, { "nct_id": "NCT07811531", "title": "A Clinical Investigation of a Topical Moisturizer on Skin Barrier Function in Adults With Sensitive Skin", "status": "RECRUITING", "phase": "Phase 4", "lead_sponsor": "Good Molecules, LLC", "conditions": [ "Sensitive Skin" ], "sites": [ "New York" ], "enrollment": 24, "start_date": "2026-09-14", "registry_url": "https://clinicaltrials.gov/study/NCT07811531" }, { "nct_id": "NCT07743580", "title": "A Study of Secutrelvir in Participants With Coronavirus Disease 2019 (COVID-19) Who Are at High Risk for Progression to Severe Disease", "status": "RECRUITING", "phase": "Phase 3", "lead_sponsor": "Shionogi", "conditions": [ "SARS-CoV-2" ], "sites": [ "Coral Gables", "Miami", "St. Petersburg", "Tampa", "Cincinnati" ], "enrollment": 2000, "start_date": "2026-09-14", "registry_url": "https://clinicaltrials.gov/study/NCT07743580" }, { "nct_id": "NCT07644585", "title": "A Pilot Study of Ultra-High Dose Rate (ConformalFLASH\u00ae), for Reirradiation of Carcinoma of the Head and Neck", "status": "RECRUITING", "phase": "Not applicable", "lead_sponsor": "IBA Proton Therapy, Inc.", "conditions": [ "Head and Neck Cancer" ], "sites": [ "Philadelphia" ], "enrollment": 10, "start_date": "2026-09-14", "registry_url": "https://clinicaltrials.gov/study/NCT07644585" }, { "nct_id": "NCT07744971", "title": "Comparison of Four Qualia Sleep Formulations on Sleep Quality : An Open-label 4-arm Pilot Study", "status": "ACTIVE_NOT_RECRUITING", "phase": "Not applicable", "lead_sponsor": "Qualia Life Sciences", "conditions": [ "Sleep Quality" ], "sites": [ "Carlsbad" ], "enrollment": 100, "start_date": "2026-09-12", "registry_url": "https://clinicaltrials.gov/study/NCT07744971" }, { "nct_id": "NCT07606365", "title": "A Study in Adults With Geographic Atrophy", "status": "RECRUITING", "phase": "Phase 2", "lead_sponsor": "Sitala Bio LTD", "conditions": [ "Geographic Atrophy" ], "sites": [ "Bakersfield", "Beverly Hills", "Aurora", "Waterford", "Lemont", "Hagerstown", "Waltham", "Hauppauge" ], "enrollment": 300, "start_date": "2026-09-11", "registry_url": "https://clinicaltrials.gov/study/NCT07606365" }, { "nct_id": "NCT07811193", "title": "A Study to Evaluate the Efficacy of VVD-133214 in Combination With Pembrolizumab Compared With Pembrolizumab Alone in Participants With Advanced Cancer of the Colon or Rectum", "status": "RECRUITING", "phase": "Phase 2", "lead_sponsor": "Vividion Therapeutics, Inc.", "conditions": [ "Colorectal Adenocarcinoma" ], "sites": [ "Tucson", "Ann Arbor", "Detroit", "Morgantown" ], "enrollment": 140, "start_date": "2026-09-11", "registry_url": "https://clinicaltrials.gov/study/NCT07811193" }, { "nct_id": "NCT07803744", "title": "A Study of Tirzepatide (LY3298176) in Participants With Type 1 Diabetes Mellitus and Overweight or Obesity", "status": "RECRUITING", "phase": "Phase 1", "lead_sponsor": "Eli Lilly and Company", "conditions": [ "Diabetes Mellitus, Type 1", "Overweight", "Obesity" ], "sites": [ "Miami" ], "enrollment": 18, "start_date": "2026-09-11", "registry_url": "https://clinicaltrials.gov/study/NCT07803744" }, { "nct_id": "NCT07321899", "title": "Transcatheter Tricuspid Valve Replacement With the Medtronic Intrepid\u2122 Transcatheter Tricuspid Valve Replacement (TTVR) System in Severe Tricuspid Regurgitation", "status": "RECRUITING", "phase": "Not applicable", "lead_sponsor": "Medtronic Cardiovascular", "conditions": [ "Severe Tricuspid Regurgitation" ], "sites": [ "Birmingham", "Phoenix", "Thousand Oaks", "New Haven", "Atlanta", "Chicago", "Minneapolis", "Buffalo" ], "enrollment": 1186, "start_date": "2026-09-11", "registry_url": "https://clinicaltrials.gov/study/NCT07321899" }, { "nct_id": "NCT07284745", "title": "A Study of KarXT + KarX-EC for Treatment of Irritability in Children and Adolescents With Autism", "status": "NOT_YET_RECRUITING", "phase": "Phase 3", "lead_sponsor": "Bristol-Myers Squibb", "conditions": [ "Irritability Associated With Autism Spectrum Disorder" ], "sites": [ "Dothan", "Phoenix", "Anaheim", "Glendale", "Redlands", "San Rafael", "Colorado Springs", "Boca Raton" ], "enrollment": 176, "start_date": "2026-09-11", "registry_url": "https://clinicaltrials.gov/study/NCT07284745" }, { "nct_id": "NCT07586774", "title": "Clinical Outcomes of 3D Printed and Milled Complete Dentures", "status": "RECRUITING", "phase": "Not applicable", "lead_sponsor": "Dentsply Sirona Implants and Consumables", "conditions": [ "Edentulous Mouth", "Edentulous Jaw" ], "sites": [ "Chapel Hill" ], "enrollment": 68, "start_date": "2026-09-11", "registry_url": "https://clinicaltrials.gov/study/NCT07586774" }, { "nct_id": "NCT07841483", "title": "AI Mental Health Tool vs. Psychoeducation Control", "status": "ACTIVE_NOT_RECRUITING", "phase": "Not applicable", "lead_sponsor": "Slingshot AI", "conditions": [ "Depressive Disorder", "Depressive Symptoms" ], "sites": [ "New York" ], "enrollment": 500, "start_date": "2026-09-11", "registry_url": "https://clinicaltrials.gov/study/NCT07841483" }, { "nct_id": "NCT07822919", "title": "A Study of AWT020 in Participants With Advanced Solid Tumors", "status": "RECRUITING", "phase": "Phase 1", "lead_sponsor": "Anwita Biosciences", "conditions": [ "Advanced Cancers (Solid Tumors)" ], "sites": [ "Plantation", "Fairfax" ], "enrollment": 96, "start_date": "2026-09-11", "registry_url": "https://clinicaltrials.gov/study/NCT07822919" }, { "nct_id": "NCT07780656", "title": "A Study to Investigate the Efficacy and Safety of GSK5784283 (Felcorekibart) Compared With Placebo in Participants With Moderate to Very Severe COPD (PERSIST COPD-2)", "status": "RECRUITING", "phase": "Phase 3", "lead_sponsor": "GlaxoSmithKline", "conditions": [ "Pulmonary Disease, Chronic Obstructive" ], "sites": [ "Miami", "Tampa", "Rapid City", "West Point" ], "enrollment": 624, "start_date": "2026-09-11", "registry_url": "https://clinicaltrials.gov/study/NCT07780656" }, { "nct_id": "NCT07788521", "title": "Comparison of ACUVUE\u00ae OASYS MAX 1-Day Multifocal and DAILIES\u00ae AquaComfort Plus\u00ae Multifocal", "status": "RECRUITING", "phase": "Not applicable", "lead_sponsor": "Johnson & Johnson Vision Care, Inc.", "conditions": [ "Visual Acuity" ], "sites": [ "Longwood", "Roswell", "St Louis", "Jamestown", "Manhattan", "Vestal", "Warwick", "Memphis" ], "enrollment": 150, "start_date": "2026-09-10", "registry_url": "https://clinicaltrials.gov/study/NCT07788521" }, { "nct_id": "NCT07680764", "title": "A Study To Assess the Safety, Tolerability, and Efficacy of Imzokitug in Combination With Pumitamig and Platinum-Doublet Chemotherapy (PDCT) Versus Pumitamig and PDCT as First-line Treatment for Participants With Locally Advanced or Metastatic Non-Small Cell Lung Cancer (NSCLC)", "status": "RECRUITING", "phase": "Phase 2", "lead_sponsor": "Bristol-Myers Squibb", "conditions": [ "Locally Advanced Non-Small Cell Lung Cancer (NSCLC)", "Metastatic Non-Small Cell Lung Cancer (NSCLC)" ], "sites": [ "Washington D.C.", "Athens", "Lexington", "Baltimore", "Hattiesburg", "Grand Island", "Omaha", "New York" ], "enrollment": 160, "start_date": "2026-09-10", "registry_url": "https://clinicaltrials.gov/study/NCT07680764" }, { "nct_id": "NCT07623161", "title": "A Study to Compare Elritercept to Placebo in Adults With Myelofibrosis and Anemia Who Are Taking Ruxolitinib", "status": "RECRUITING", "phase": "Phase 3", "lead_sponsor": "Takeda", "conditions": [ "Myelofibrosis", "Anemia" ], "sites": [ "Gilbert", "Glendale", "Whittier", "Washington D.C.", "Coral Springs", "Miami", "Orlando", "Tamarac" ], "enrollment": 324, "start_date": "2026-09-10", "registry_url": "https://clinicaltrials.gov/study/NCT07623161" }, { "nct_id": "NCT07619118", "title": "A Phase III Study to Assess the Effect of FDC Laroprovstat/Rosuvastatin Compared With Rosuvastatin on LDL-C in Patients With Hypercholesterolaemia", "status": "RECRUITING", "phase": "Phase 3", "lead_sponsor": "AstraZeneca", "conditions": [ "Hypercholesterolaemia" ], "sites": [ "Sun City West", "Gardena", "Lomita", "Pomona", "Sacramento", "Jacksonville", "Miami Lakes", "Orlando" ], "enrollment": 200, "start_date": "2026-09-10", "registry_url": "https://clinicaltrials.gov/study/NCT07619118" }, { "nct_id": "NCT07780786", "title": "Non-invasive Saphenous Nerve Stimulation Therapy for Overactive Bladder", "status": "NOT_YET_RECRUITING", "phase": "Phase 3", "lead_sponsor": "NinaMED Pty Ltd", "conditions": [ "Overactive Bladder (OAB)" ], "sites": [ "Camden" ], "enrollment": 290, "start_date": "2026-09-10", "registry_url": "https://clinicaltrials.gov/study/NCT07780786" }, { "nct_id": "NCT07807891", "title": "Safety and Tolerability of an Ultra Absorbency Menstrual Tampon Compared to a Commercially Marketed Tampon", "status": "RECRUITING", "phase": "Not applicable", "lead_sponsor": "Lyv Life Inc. (dba: Cora)", "conditions": [ "Safety and Tolerability in Healthy Volunteers" ], "sites": [ "St. Petersburg" ], "enrollment": 120, "start_date": "2026-09-10", "registry_url": "https://clinicaltrials.gov/study/NCT07807891" }, { "nct_id": "NCT07815665", "title": "A Study of Ivonescimab in Combination With Enfortumab Vedotin vs Pembrolizumab in Combination With Enfortumab Vedotin in Metastatic Urothelial Carcinoma", "status": "RECRUITING", "phase": "Phase 2/3", "lead_sponsor": "Summit Therapeutics", "conditions": [ "Metastatic Urothelial Carcinoma", "Metastatic Urothelial Carcinoma (UC)" ], "sites": [ "Phoenix", "Los Angeles", "Washington D.C.", "Jacksonville", "Rochester", "Nashville", "Spokane" ], "enrollment": 800, "start_date": "2026-09-10", "registry_url": "https://clinicaltrials.gov/study/NCT07815665" }, { "nct_id": "NCT07819305", "title": "Evaluation of Approved Contact Lenses (CR-6657)", "status": "RECRUITING", "phase": "Not applicable", "lead_sponsor": "Johnson & Johnson Vision Care, Inc.", "conditions": [ "Visual Acuity" ], "sites": [ "Jacksonville", "Franklin Park", "Camden", "Granville", "New Bremen", "Memphis", "Houston", "Salem" ], "enrollment": 150, "start_date": "2026-09-10", "registry_url": "https://clinicaltrials.gov/study/NCT07819305" }, { "nct_id": "NCT07743151", "title": "A Clinical Trial of MK-1406 in Healthy Participants (MK-1406-008)", "status": "RECRUITING", "phase": "Phase 1", "lead_sponsor": "Merck Sharp & Dohme LLC", "conditions": [ "Healthy" ], "sites": [ "Hollywood", "South Miami", "Baltimore", "Springfield", "Marlton", "Cleveland", "San Antonio" ], "enrollment": 400, "start_date": "2026-09-10", "registry_url": "https://clinicaltrials.gov/study/NCT07743151" }, { "nct_id": "NCT07813637", "title": "Phase 1 Trial to Study JANX013 and JANX007 Combination in mCRPC", "status": "RECRUITING", "phase": "Phase 1", "lead_sponsor": "Janux Therapeutics", "conditions": [ "Prostate Cancer", "Castration-Resistant Prostate Cancer (CRPC)", "Metastatic Prostate Cancer", "Metastatic Castration-Resistant Prostate Cancer Patients" ], "sites": [ "Nashville" ], "enrollment": 110, "start_date": "2026-09-10", "registry_url": "https://clinicaltrials.gov/study/NCT07813637" }, { "nct_id": "NCT07787169", "title": "A Master Protocol Studying Multiple Amyloid-Targeting Therapies in Healthy Participants and Participants With Alzheimer's Disease", "status": "RECRUITING", "phase": "Phase 1", "lead_sponsor": "Eli Lilly and Company", "conditions": [ "Alzheimer Disease", "Amyloid", "Plaque, Amyloid", "Healthy Volunteers" ], "sites": [ "Anaheim", "Irvine", "Los Alamitos", "Daytona Beach", "Lady Lake", "Maitland", "Orlando", "Port Orange" ], "enrollment": 179, "start_date": "2026-09-09", "registry_url": "https://clinicaltrials.gov/study/NCT07787169" }, { "nct_id": "NCT07819097", "title": "A Study to Learn About the Safety and Immune Responses of RSVpreF in Older Adults", "status": "RECRUITING", "phase": "Phase 3", "lead_sponsor": "Pfizer", "conditions": [ "Adult", "Healthy Participants" ], "sites": [ "Scottsdale", "Lake Forest", "Riverside", "Milford", "Washington D.C.", "Meridian", "Evansville", "Warren Township" ], "enrollment": 600, "start_date": "2026-09-09", "registry_url": "https://clinicaltrials.gov/study/NCT07819097" }, { "nct_id": "NCT07642284", "title": "Clinical Performance of AH Plus Jet\u00ae Root Canal Sealers in Single-cone Protocols", "status": "RECRUITING", "phase": "Not applicable", "lead_sponsor": "Dentsply Sirona Implants and Consumables", "conditions": [ "Root Canal Treatment" ], "sites": [ "New York" ], "enrollment": 130, "start_date": "2026-09-09", "registry_url": "https://clinicaltrials.gov/study/NCT07642284" }, { "nct_id": "NCT07602855", "title": "A Study of Risvutatug Rezetecan in Combination With Ivonescimab in Participants With Advanced Solid Tumors (EMBOLD PanTumour-103)", "status": "RECRUITING", "phase": "Phase 1/2", "lead_sponsor": "GlaxoSmithKline", "conditions": [ "Neoplasms, Lung" ], "sites": [ "Los Angeles", "Wilson", "Canton" ], "enrollment": 184, "start_date": "2026-09-09", "registry_url": "https://clinicaltrials.gov/study/NCT07602855" }, { "nct_id": "NCT07871708", "title": "Clinical Evaluation of a Multi-functional Beauty Device on Cosmetic Skin Outcomes", "status": "RECRUITING", "phase": "Not applicable", "lead_sponsor": "APR Co., Ltd.", "conditions": [ "Skin Appearance", "Skin Texture", "Skin Sagging", "Wrinkles" ], "sites": [ "Baltimore" ], "enrollment": 50, "start_date": "2026-09-09", "registry_url": "https://clinicaltrials.gov/study/NCT07871708" }, { "nct_id": "NCT07893561", "title": "A Clinical Trial to Evaluate the Effects of Adrenal Adapt on Sleep Quality, Daytime Energy, Stress Resilience, and Cognitive Performance.", "status": "RECRUITING", "phase": "Not applicable", "lead_sponsor": "Bioligent", "conditions": [ "Improves Daytime Energy Levels", "Reduces Afternoon Energy Crashes and Midday Fatigue", "Improves Overall Sleep Quality and Restorative Sleep", "Helps People Fall Asleep Faster and Wake Less During the Night" ], "sites": [ "Las Vegas" ], "enrollment": 40, "start_date": "2026-09-09", "registry_url": "https://clinicaltrials.gov/study/NCT07893561" }, { "nct_id": "NCT07782333", "title": "A Study Evaluating TRIV-573 in Atopic Dermatitis", "status": "RECRUITING", "phase": "Phase 2", "lead_sponsor": "Triveni Bio", "conditions": [ "Atopic Dermatitis" ], "sites": [ "Fountain Valley", "Los Angeles", "Boca Raton", "Miami", "Indianapolis", "Bay City", "Boardman", "Camp Hill" ], "enrollment": 90, "start_date": "2026-09-09", "registry_url": "https://clinicaltrials.gov/study/NCT07782333" }, { "nct_id": "NCT07819773", "title": "Device for Treating Generalized Anxiety", "status": "RECRUITING", "phase": "Not applicable", "lead_sponsor": "BTL Industries Ltd.", "conditions": [ "Generalized Anxiety Disorder (GAD)" ], "sites": [ "Denver", "Chicago", "Newburgh" ], "enrollment": 40, "start_date": "2026-09-09", "registry_url": "https://clinicaltrials.gov/study/NCT07819773" }, { "nct_id": "NCT07741604", "title": "A Study Investigating the Safety of RO7795081 and How the Body Processes RO7795081 in People With Normal or Decreased Kidney Functions", "status": "RECRUITING", "phase": "Phase 1", "lead_sponsor": "Hoffmann-La Roche", "conditions": [ "Renal Impairment" ], "sites": [ "Miami Lakes", "Orlando", "St. Petersburg" ], "enrollment": 60, "start_date": "2026-09-09", "registry_url": "https://clinicaltrials.gov/study/NCT07741604" }, { "nct_id": "NCT07640984", "title": "A Phase I/II Trial of JR-446 in Mucopolysaccharidosis Type IIIB (MPS IIIB)", "status": "RECRUITING", "phase": "Phase 1/2", "lead_sponsor": "JCR Pharmaceuticals Co., Ltd.", "conditions": [ "Mucopolysaccharidosis IIIB" ], "sites": [ "Oakland", "Pittsburgh", "Fairfax" ], "enrollment": 12, "start_date": "2026-09-09", "registry_url": "https://clinicaltrials.gov/study/NCT07640984" }, { "nct_id": "NCT07794748", "title": "A Study to Assess the Safety, Tolerability, and Immunogenicity of 3 Lots of a Multivalent Pneumococcal Conjugate Vaccine Administered to Adults", "status": "RECRUITING", "phase": "Phase 3", "lead_sponsor": "Pfizer", "conditions": [ "Pneumococcal Disease" ], "sites": [ "Birmingham", "Lake Forest", "Walnut Creek", "Milford", "Doral", "Hollywood", "Jacksonville", "Miami" ], "enrollment": 4670, "start_date": "2026-09-08", "registry_url": "https://clinicaltrials.gov/study/NCT07794748" }, { "nct_id": "NCT07444476", "title": "A Study to Learn About Salanersen's (BIIB115) Effects on Movement and Its Safety in Participants Aged 15 to 60 Years With Spinal Muscular Atrophy (SMA) Who Are Either New to SMA Treatment or Were Previously Treated With Risdiplam", "status": "RECRUITING", "phase": "Phase 3", "lead_sponsor": "Biogen", "conditions": [ "Spinal Muscular Atrophy" ], "sites": [ "Palo Alto", "Norfolk" ], "enrollment": 90, "start_date": "2026-09-08", "registry_url": "https://clinicaltrials.gov/study/NCT07444476" }, { "nct_id": "NCT07680790", "title": "Study of Izalontamab Brengitecan (BMS-986507) in Combination With Osimertinib Versus Osimertinib Monotherapy or Osimertinib in Combination With Platinum-based Chemotherapy for EGFRmt Non-small Cell Lung Cancer (IZABRIGHT-Lung02)", "status": "RECRUITING", "phase": "Phase 3", "lead_sponsor": "Bristol-Myers Squibb", "conditions": [ "Non-Small Cell Lung Cancer" ], "sites": [ "Beverly Hills", "Fullerton", "La Jolla", "Boulder", "Fort Myers", "Orlando", "Palm Bay", "St. Petersburg" ], "enrollment": 850, "start_date": "2026-09-08", "registry_url": "https://clinicaltrials.gov/study/NCT07680790" }, { "nct_id": "NCT07623200", "title": "A Phase 3 Study of INCA033989 Versus Best Available Therapy in Participants With Essential Thrombocythemia", "status": "RECRUITING", "phase": "Phase 3", "lead_sponsor": "Incyte Corporation", "conditions": [ "Essential Thrombocythemia" ], "sites": [ "Birmingham", "Gilbert", "Duarte", "Greenbrae", "La Jolla", "Los Angeles", "Palo Alto", "Lone Tree" ], "enrollment": 426, "start_date": "2026-09-08", "registry_url": "https://clinicaltrials.gov/study/NCT07623200" }, { "nct_id": "NCT07802717", "title": "A Phase 1 Dose-escalation and Expansion Study of In Vivo BCMA-CAR T Cell Therapy (VV169) in Patients With Relapsed or Refractory Multiple Myeloma", "status": "RECRUITING", "phase": "Phase 1", "lead_sponsor": "Vyriad, Inc.", "conditions": [ "Multiple Myeloma Refractory", "Multiple Myeloma in Relapse" ], "sites": [ "Rochester" ], "enrollment": 40, "start_date": "2026-09-08", "registry_url": "https://clinicaltrials.gov/study/NCT07802717" }, { "nct_id": "NCT07543055", "title": "A Phase 1 Study of BPX-601 CAR T-Cell Therapy in Adult Participants With Prostate Cancer That Has Returned, is Resistant to Treatment and Has Spread", "status": "RECRUITING", "phase": "Phase 1", "lead_sponsor": "Regeneron Pharmaceuticals", "conditions": [ "Prostate Cancer" ], "sites": [ "Atlanta", "Hackensack", "Portland" ], "enrollment": 36, "start_date": "2026-09-08", "registry_url": "https://clinicaltrials.gov/study/NCT07543055" } ] }