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Trackers› Clinical trials› USA
Clinical trial register · United States · industry-sponsored

Industry-sponsored studies with a US investigative site

Every industry-sponsored study on the ClinicalTrials.gov registry that lists a US site and is open, about to open, active-but-closed, or enrolling by invitation. This deliberately excludes academic and other non-industry sponsors โ€” the full US registry across all sponsors runs to over 22,000 recruiting studies alone.

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Source: ClinicalTrials.gov. Complete coverage of the industry-sponsored slice โ€” all 9112 matching records are in this view (non-industry sponsors are out of scope by design, not truncated). Synced 23 Sep 2026, 03:16 UTC
9112
Studies in scope
industry-sponsored, all four open statuses
4950
Recruiting now
open to new participants
2202
Lead sponsors
across recruiting studies
Top states
California 5295 Florida 4397 Illinois 2479 Georgia 2346 Arizona 2231
Narrow the register
Recruitment status
Phase
Lead sponsor
AstraZeneca299 Novartis Pharmaceuticals202 Eli Lilly and Company190 Merck Sharp & Dohme LLC183 AbbVie172
State
California5295 Florida4397 Illinois2479 Georgia2346 Arizona2231
All 51 states
Target enrolment
to
9112 of 9112 studies
Download
Status
Study
Lead sponsor
Phase
Enrol
US states
Start
Not yet open
Safety and Tolerability of IRX-101 in Patients Receiving Intravitreal Injections
NCT05750589Retinal Disease
iRenix Medical, Inc.
Phase 3
240
Texas
2026-09-01
By invitation
Multimodal Digital Biomarker Prediction of Acute Clinical Deterioration
NCT07817550Acute Disease, Disease Progression, Critical Illness, Biomarkers
Truway Health, Inc.
Observational
10,000
New York
2026-09-01
Not yet open
A Study to Evaluate the Safety, Reactogenicity, and Immunogenicity of mRNA-1283 in Participants โ‰ฅ6 Months to <12 Years of Age
NCT07808697SARS-CoV-2
ModernaTX, Inc.
Phase 2
300
California, Florida, Illinois, Michigan, Ohio, Texas, Utah, Virginia
2026-09-01
Not yet open
Hypoxic Red Blood Cells in Sickle Cell Anemia
NCT06743113Sickle Cell Anaemia, Sickle Cell Anemia Crisis, Sickle Cell Anemia in Children, Sickle Cell Anemia (HbSS, or HbSฮฒ-thalassemia0)
Hemanext
Not applicable
48
Connecticut, Georgia, Illinois, Maryland, Pennsylvania
2026-09-01
By invitation
Clinical Time and Temporal Dynamics Study (CLIN-TIME)
NCT07812831Longitudinal Studies, Prospective Studies, Biomarkers, Predictive Value of Tests
Truway Health, Inc.
Observational
1,000
New York
2026-09-01
Not yet open
Human Milk Concentrating Device to Optimize Mother's Own Milk
NCT07576972Preterm Infant Health, Premature Babies
Mother's Milk is Best
Not applicable
310
Connecticut
2026-09-01
Not yet open
A Comparison of Cosmos Rx Medication Adherence Platform vs. Pharmacy Fill Adherence Measures
NCT07712614GERD (Gastroesophageal Reflux Disease)
Cosmos Rx, Inc
Not applicable
50
Maryland
2026-09-01
Recruiting
EFS of Posterior Leaflet Replacement to Reduce Mitral Regurgitation (United States)
NCT07517588Mitral Regurgitation
Polares Medical SA
Not applicable
15
Georgia, New York, Ohio
2026-09-01
Recruiting
Brain Stimulation Paired With Structured Language Learning in Adults
NCT07762118Language Development, Learning
General Neuro Inc.
Not applicable
60
Massachusetts
2026-09-01
Not yet open
Evaluation of the Efficacy and Tolerability of the LED Mask With or Without the Serum Formula on the Signs of Facial Photodamage .
NCT07661004Photodamage of the Face, Anti Aging
L'Oreal
Not applicable
130
New Jersey
2026-09-01
Recruiting
Long-term Safety of Eplontersen Treated aTTR Patients and in Liver Transplant and Severely Hepatic Impaired Subpopulations
NCT07654855Transthyretin Amyloidosis, Transthyretin Amyloidosis With Cardiomyopathy, Transthyretin Amyloidosis With Polyneuropathy
AstraZeneca
Observational
320
California
2026-09-01
By invitation
Self-Reported Hydration and Nutrition Habits and Knowledge Among Frontline Workers in Manufacturing Facilities
NCT07733999Hydration, Nutrition, Industrial Athlete
PepsiCo Global R&D
Observational
1,000
New York
2026-09-01
Not yet open
A Study of Mezagitamab in Adults With Late Antibody-Mediated Rejection (AMR) After a Kidney Transplant
NCT07613359Antibody-Mediated Rejection (AMR)
Takeda
Phase 2
36
California, Florida, Maryland, Missouri, New Jersey, New York, Ohio, Texas
2026-09-01
Not yet open
Evaluating the Safety and Immunogenicity of Polyvalent DNA and Recombinant gp120 Protein HIV Vaccine (PDPHV) in Healthy, HIV-uninfected Adults
NCT07675629HIV Prevention
Worcester HIV Vaccine
Phase 2
126
Massachusetts
2026-09-01
Not yet open
Mild Cognitive Impairment Community Screening and Early Intervention Via Stem Cell Therapy and Wearable Brain Computer Interface Device.
NCT07214974Mild Cognitive Impairment (MCI), Early Stages of Cognitive Decline, Alzheimer's Disease Dementia, Alzheimer's Disease Diagnosis
Noah Tech, Corp.
Phase EARLY_PHASE1
600
New Jersey
2026-09-01
Not yet open
AMAZE 9: A Research Study Investigating How Well Zenagamtide Tablets Help People With Excess Body Weight Lose Weight
NCT07720271Overweight, Obesity
Novo Nordisk A/S
Phase 3
950
Alabama, California, Colorado, Florida, Georgia, Hawaii, Illinois, Indiana
2026-09-01
Not yet open
Open Label, Multi-Center Study, Evaluating the Effect of Adipose Tissue Processed With the SyntrFugeโ„ข System for Facial Fat Grafting
NCT05522426Facial Atrophy and Loss of Contour
Syntr Health Technologies, Inc.
Not applicable
50
California
2026-09-01
Recruiting
Randomized Evaluation of Natural Extract for Menopausal Wellness (RENEW)
NCT07834463Menopause, Hot Flashes
India Glycols Ltd
Not applicable
100
Florida
2026-09-01
Not yet open
To Evaluate the Clinical Impact of the Point Powered System
NCT07135947Amputation; Traumatic, Hand
Point Designs
Not applicable
10
Colorado
2026-09-01
Not yet open
Rollover Study for Participants Who Have Completed a Previous Clinical Study With Anifrolumab (Saphnelo) and Clinically Benefited From Continued Treatment
NCT07691970Systemic Sclerosis Cutaneous Lupus E Myopathies Systemic Lupus Erythematosus
AstraZeneca
Phase 3
1,072
California, Florida, Illinois, Michigan, New York, South Carolina
2026-09-01
Not yet open
A Study of AL58805 in Advanced, Metastatic GYN, STS or Breast Cancers
NCT07811232Endometrial Neoplasms, Soft Tissue Sarcoma (STS), Breast Neoplasms
Advenchen Pharmaceuticals, LLC.
Phase 1/2
138
Texas
2026-09-01
Not yet open
INitiation and Titration of Guideline Directed Medical TheRApy in HearT Failure Cardiogenic Shock With ImpElla 5.5 for Cardiac Recovery
NCT06965504Heart Failure, Cardiogenic Shock, Reduced Ejection Fraction Heart Failure
Abiomed Inc.
Not applicable
250
Florida, Indiana, Minnesota, Missouri, New Jersey, North Carolina, Pennsylvania, Tennessee
2026-09-01
Recruiting
A Study to Test the Effects of Centanafadine in Adults With Attention-deficit/Hyperactivity Disorder and Emotional Dysregulation
NCT07759154Attention-deficit/Hyperactivity Disorder, Emotional Dysregulation
Otsuka Pharmaceutical Development & Commercialization, Inc.
Phase 3
80
Florida, Louisiana, Massachusetts, Missouri, Nevada, New Jersey, New York, Ohio
2026-09-01
Not yet open
A Randomized, Double-Blind Controlled Comparison of NRX-101 vs. Placebo for Adults Being Treated With Robotic Transcranial Magnetic Stimulation for Treatment Resistant Depression: The SPARC-TMS Trial
NCT07227103Treatment Resistant Depression, Treatment Resistant Depression (TRD)
NeuroRx, Inc.
Phase 2/3
400
Florida, Massachusetts
2026-09-01
Not yet open
A Study of Catequentinib Hydrochloride (AL3818) in Endometrial, LGSOC, STS or GBM Cancers
NCT07811297Endometrial Neoplasms, Ovarian Neoplasms, Soft Tissue Sarcoma (STS), Glioblastoma
Advenchen Pharmaceuticals, LLC.
Phase 1/2
138
Texas
2026-09-01
Not yet open
"Discovery2" Study of Using MCG at Emergency Departments
NCT07822581Acute Coronary Syndromes (ACS), Coronary Artery Disease (CAD), Chest Pain, NSTE-ACS (NSTEMI and UA)
SB Technology, Inc.
Observational
200
California
2026-09-01
By invitation
OsteoFlo HydroFiber Ambispective Evaluation
NCT07784673OsteoFlo HydroFiber
SurGenTec LLC
Observational
100
Illinois, Indiana
2026-09-01
Not yet open
2-Hydroxybenzylamine (2-HOBA) Study in Early Alzheimer's Patients
NCT06432166Alzheimer Disease, Mild Cognitive Impairment
MTI Biotech Inc
Phase 1/2
48
Tennessee
2026-09-01
Not yet open
Evaluation of the Distribution of 64Cu/68Ga Labeled CM500 in Healthy Volunteers and Patients With Cancer
NCT07781852Bladder Cancer, Glioma, Glioblastoma (GBM), Breast Cancer
Lumina Pharmaceuticals Inc
Phase EARLY_PHASE1
40
Massachusetts, Michigan, New York
2026-09-01
Not yet open
Radicle PerformanceTM VKN: A Study Assessing the Impact of Health and Wellness Products on Fatigue and Related Health Outcomes
NCT07802587Fatigue
Radicle Science
Not applicable
650
California
2026-09-01
Not yet open
Intracardiac Echocardiography Catheter Supply-Chain Reliability and Clinical Access Study
NCT07788040Cardiovascular Diseases, Arrhythmias, Cardiac, Atrial Fibrillation
Truway Health, Inc.
Observational
200
New York
2026-09-01
Recruiting
A Clinical Trial to Evaluate the Effects of a Powder Supplement in Supporting Lean Muscle Development, Hormone-Related Wellness, Digestive Comfort, Dermatologic Health, and Overall Wellness
NCT07766395Lean Muscle Development, Muscular Endurance, Hormone-Related Wellness, Digestive Comfort
Clean Nutraceuticals
Not applicable
35
Nevada
2026-09
Not yet open
An Investigation of FID 123472 Ophthalmic Solution to Vehicle for the Reduction of Ocular Redness in Adults
NCT07578363Ocular Hyperemia
Alcon Research
Phase 3
178
Texas
2026-09
Recruiting
Brexanolone Lifting Outcomes Of Moms
NCT07822321Depression, Postpartum, Postpartum Depression (PPD), Post-partum Depression, Postnatal Depression
Lipocine Inc.
Phase 3
120
Arizona, California, Colorado, Georgia, Idaho, Illinois, Louisiana, Nevada
2026-09
Not yet open
Study of EO2002 in Subjects With Corneal Edema Secondary to Corneal Endothelial Dysfunction
NCT07729137Corneal Edema, Fuchs, Fuchs Dystrophy, Fuchs' Endothelial Dystrophy
Emmecell
Phase 2
121
California
2026-09
By invitation
Continued Access to the Endogenex System for Participants in the ReCET Pivotal Study
NCT07197788Type 2 Diabetes Mellitus, Type2diabetes, Diabetes Mellitus, Type 2, Type 2 Diabetes
Endogenex, Inc.
Not applicable
50
Florida, Massachusetts, New Jersey, North Carolina, Texas
2026-09
Not yet open
A Study of WGI-0301 Plus Lenvatinib in Patients With Advanced HCC
NCT07540832Advanced Hepatocellular Carcinoma (HCC)
Zhejiang Haichang Biotech Co., Ltd.
Phase 1/2
80
New York
2026-09
Recruiting
A Phase IIa Study of ICG318 CAR-T in Refractory Systemic Lupus Erythematosus With or Without Lupus Nephritis
NCT07328581Systemic Lupus Erythematosus (SLE), Lupus Nephritis (LN)
iCell Gene Therapeutics
Phase 2
20
Illinois, New York, Pennsylvania
2026-09
Not yet open
Wellness Program Participation and Changes in Health and Quality of Life in Adults and Children
NCT07832981Health and Wellness
Dr. Goodenowe Research LLC
Observational
100
California
2026-09
Recruiting
Study to Evaluate the Efficacy and Safety of Ponesimod (VSP-128) in Patients With Moderately to Severely Active Ulcerative Colitis
NCT07686081Ulcerative Colitis (UC)
Vanda Pharmaceuticals
Phase 3
150
California, Tennessee
2026-09
Recruiting
L19IL2/L19TNF in Patients With Cutaneous Squamous Cell Carcinoma
NCT07228442Locally Advanced Cutaneous Squamous Cell Carcinoma
Philogen S.p.A.
Phase 2
92
California, Georgia, Massachusetts, North Carolina, Ohio, Texas
2026-09
Recruiting
Study of Adjuvant Darovasertib and Crizotinib in Participants With Primary Non-metastatic Uveal Melanoma
NCT07804186Uveal Melanoma
IDEAYA Biosciences
Phase 3
450
Arizona, California, Massachusetts, Michigan, New York, North Carolina, Ohio, Pennsylvania
2026-09
Not yet open
Clinical Outcomes After Treatment of Distal Humerus Fractures With the LORRAINE 2.5/3.5 mm Distal Humerus System
NCT07774091Intra-Articular or Extra-Articular Distal Humerus Fracture, Distal Humerus Fracture
Bonebridge AG
Observational
100
Texas
2026-09
Not yet open
New Functional Ingredient for Oral Care
NCT07771907Oral Health Related Quality of Life (OHRQoL)
Access Business Group
Not applicable
100
Michigan
2026-09
Not yet open
Investigation of the Interplay Between Local Oral Inflammation, Microbiota and Systemic Immune Responses.
NCT06966492Gingival Inflammation
Colgate Palmolive
Phase 4
20
Texas
2026-09
Recruiting
Study Evaluating the Efficacy and Safety of RAP-219 in Adult Participants With Focal Seizures
NCT07594119Focal Seizure, Epilepsy, Focal Epilepsy
Rapport Therapeutics Inc.
Phase 3
312
Alabama, Arkansas, Colorado, Florida, Illinois, New York, North Carolina, Tennessee
2026-09
Not yet open
Reduction of Anxiety Through Dual Treatment: Digital CBT & NBHWC Coaching
NCT07140497Hearing Disability, Anxiety, Mobility Disability
Toivoa Inc
Not applicable
200
Delaware, New Jersey, Ohio, Texas
2026-09
Recruiting
Personalized Neoantigen Vaccine Plus IL-12 (INO-9012) Versus Active Surveillance in Subjects With High-Risk HCC
NCT07722741HCC
Geneos Therapeutics
Phase 2
90
Georgia, Louisiana, Maryland, Michigan, New York, Texas, Washington
2026-09
Not yet open
UNITY DX Cornea Study
NCT07768735Tomography
Alcon Research
Observational
110
Utah
2026-09
Recruiting
A Phase 3 Study to Evaluate the Efficacy and Safety of Samelisant in Patients With Narcolepsy (AWAKE)
NCT07540364Narcolepsy
Suven Life Sciences Limited
Phase 3
240
South Carolina
2026-09
Not yet open
A Study to Assess the Efficacy and Safety of Elismetrep (K-304) in the Acute Treatment of Migraine
NCT07816367Migraine
Kallyope Inc.
Phase 3
1,500
Arizona, Arkansas, California, Colorado, Connecticut, Florida, Georgia, Idaho
2026-09
Not yet open
Chemotherapy With or Without IMD10 (Focused Ultrasound) in the Treatment of Borderline Resectable or Locally Advanced Pancreatic Cancer
NCT07325214Pancreatic Cancer, Borderline Resectable Pancreatic Cancer, Locally Advanced Pancreatic Cancer
IMGT Co., Ltd.
Not applicable
360
Massachusetts, Texas, Virginia
2026-09
Recruiting
A Study Evaluating Ficerafusp Alfa (BCA101) QW in Combination With Pembrolizumab vs Alternative Ficerafusp Alfa Dosing in 1L R or M HNSCC
NCT07807163Metastatic Head and Neck Squamous Cell Carcinoma, Recurrent Head and Neck Squamous Cell Carcinoma
Bicara Therapeutics
Phase 2
160
Texas
2026-09
Not yet open
An Open-Label Trial of Veligrotug in Participants With Thyroid Eye Disease Who Previously Responded to Teprotumumab
NCT07832136Thyroid Eye Disease
Viridian Therapeutics, Inc.
Phase 4
30
California, Florida, Massachusetts, Michigan, Missouri, New Jersey, Texas
2026-09
Not yet open
A Study of LY5625575 in Healthy Participants and in Participants With Inflammation (Elevated C-Reactive Protein)
NCT07801300Healthy Volunteers, C-Reactive Protein
Eli Lilly and Company
Phase 1
204
Florida, Texas
2026-09
Recruiting
A First-in-Human Study of KK2223 in Participants With Relapsed or Refractory T Cell Non-Hodgkin Lymphoma
NCT07192471T-cell NHL (PTCL or CTCL)
Kyowa Kirin, Inc.
Phase 1
72
California, Florida, Georgia, Iowa, Massachusetts, Missouri, New Jersey, New York
2026-09
Not yet open
Combination Immunotherapy Treatment for Glioblastoma Including BreakVax ImmunoTreatment (Designed and Manufactured Per Patient), Chemotherapy and Anti PD-1 Therapy
NCT07762716Glioblastoma (GBM)
BreakBio Corp
Phase 1/2
10
Florida
2026-09
Not yet open
A Study of SPY072 in Adults With Moderate to Severe Hidradenitis Suppurativa (The SKYLIGHT Trial)
NCT07766005Hidradenitis Suppurativa (HS)
Spyre Therapeutics, Inc.
Phase 2
150
California, Indiana, Kentucky, Louisiana, Massachusetts, New York, South Carolina, Texas
2026-09
Recruiting
Study of YOLT-203 in Children and Adults With Primary Hyperoxaluria Type 1 (PH1)
NCT07587021Primary Hyperoxaluria Type 1, PH1
YolTech Therapeutics Co., Ltd
Phase 2
36
Alabama, Colorado, Missouri, Pennsylvania
2026-09
Recruiting
A Clinical Trial to Evaluate the Effects of an Omega-3-containing Supplement on DHA and EPA Levels in the Blood
NCT07753174Omega-3 Deficiency, DHA and EPA Blood Levels, Cardiovascular Health, Cognitive Health
Revive Active
Not applicable
49
Nevada
2026-09
Not yet open
A Trial to Assess the Safety and Effectiveness of an Anatomic Total Shoulder System
NCT07812324Shoulder Arthroplasty, Total Shoulder Arthroplasty
Medacta USA
Not applicable
286
Arizona, Florida, Indiana, Maryland, New Hampshire, New York, Oregon, Pennsylvania
2026-09
Not yet open
Combination Immunotherapy Treatment for Locally Advanced Unresectable or Metastatic, PD-L1 Negative (CPS<10), gBRCA Negative, Triple Negative Breast Cancer Including BreakVax ImmunoTreatment (Designed and Manufactured Per Patient), Chemotherapy and Anti PD-1 Therapy
NCT07762703Triple-Negative Breast Cancer (TNBC)
BreakBio Corp
Phase 1/2
10
Florida
2026-09
Recruiting
A Study to Investigate the Efficacy, Pharmacokinetics, and Safety of Mitapivat in Pediatric Participants With ฮฑ- or ฮฒ-Non-Transfusion-Dependent Thalassemia
NCT07517133Non-Transfusion-dependent Alpha-Thalassemia, Non-Transfusion-dependent Beta-Thalassemia
Agios Pharmaceuticals, Inc.
Phase 3
45
California, New York, Pennsylvania, Texas
2026-09
Recruiting
JUR-003 in Adult Patients With Metastatic Prostate Cancer
NCT07824349Metastatic Castration Resistant Prostate Cancer, Oligometastatic Prostate Cancer (OMPC), Metastatic Hormone Sensitive Prostate Cancer
Juri Biosciences, Inc.
Phase 1
210
Michigan, New York, Tennessee
2026-09
Not yet open
Study of ChoironeX GalKO Porcine Thymokidney Xenotransplantation in End-Stage Renal Disease
NCT07696962End Stage Renal Disease
Xeno Holdings (US), LLC dba ChoironeX
Phase 1
4
New York
2026-09
Not yet open
A Study of LY4405094 in Healthy Participants and Participants With Alzheimer's Disease
NCT07787182Healthy Volunteers, Alzheimer Disease, Amyloid, Plaque, Amyloid
Eli Lilly and Company
Phase 1
68
California, Florida, Georgia, Michigan
2026-09
Recruiting
Hormone-free Antral Retrieval for Viable Embryo Storage & Transfer
NCT07801105Infertility
Kevin Doody
Not applicable
30
Texas
2026-09
Not yet open
Efficacy, Safety, and Pharmacokinetics of Tirzepatide (LY3298176) Once Weekly Versus Placebo in Pediatric Participants 6 to Less Than 12 Years of Age Who Have Obesity (ADVANCE-SURMOUNT-KIDS)
NCT07817875Obesity
Eli Lilly and Company
Phase 3
150
Arizona, California, Colorado, Connecticut, Florida, Georgia, Illinois, Indiana
2026-09
Recruiting
L19IL2/TNF in Patients With Basal Cell Carcinoma
NCT07227870Locally Advanced Basal Cell Carcinoma
Philogen S.p.A.
Phase 2
92
Florida, Georgia, New York, Ohio, Texas
2026-09
Recruiting
A Study to Investigate the Efficacy, Pharmacokinetics, and Safety of Mitapivat in Pediatric Participants With Transfusion-Dependent Alpha- or Beta-Thalassemia (ฮฑ- or ฮฒ-TDT)
NCT07506863Transfusion-dependent Alpha-Thalassemia, Transfusion-dependent Beta-Thalassemia
Agios Pharmaceuticals, Inc.
Phase 3
54
New York, Pennsylvania, Texas
2026-09
Not yet open
WATER IV PCa (AS Sub-study)
NCT07650448Localized Prostate Cancer
PROCEPT BioRobotics
Not applicable
333
Arizona, California, Colorado, Florida, Georgia, Idaho, Illinois, Maryland
2026-09
Not yet open
Study of the Pharmacokinetics, Safety, and Tolerability of ZONISADE in Children 1 Month to 17 Years of Age With Partial-onset Seizures
NCT06534502Seizures, Seizures, Focal, Seizure, Partial Onset, Seizure Disorder, Partial
Azurity Pharmaceuticals
Phase 4
40
North Carolina, Tennessee
2026-09
Not yet open
A Phase 1/2 Trial of ADI-212 in mCRPC
NCT07793435Prostate Cancer Metastatic
Adicet Therapeutics
Phase 1/2
12
California
2026-09
Recruiting
A Trial to Assess the Efficacy and Safety of Engasertib in Participants With Moderate to Severe Hereditary Hemorrhagic Telangiectasia (HHT)
NCT07743671Hereditary Hemorrhagic Telangiectasia
Vaderis Therapeutics AG
Phase 3
240
Illinois, Indiana, Minnesota, Missouri
2026-09
Recruiting
A Study of the Safety and Efficacy of Prime Editing (PM577) in Participants With Wilson Disease (WD)
NCT07748403Wilson Disease, Wilson's Disease, Wilsons Disease
Prime Medicine, Inc.
Phase 1/2
42
Illinois, Texas
2026-09
Not yet open
A Study of Orforglipron (LY3502970) Compared With Dulaglutide in Pediatric Participants With Type 2 Diabetes
NCT07668336Diabetes Mellitus, Type 2
Eli Lilly and Company
Phase 3
170
California, Connecticut, Georgia, Idaho, Kansas, New York, Oklahoma, Pennsylvania
2026-09
Not yet open
An Observational Study of Patients With Dermatologic Disease
NCT07748169Vitiligo, Atopic Dermatitis, Alopecia Areata, Hidradenitis Suppurativa (HS)
Target PharmaSolutions, Inc.
Observational
2,000,000
New York
2026-09
Not yet open
HiCM-188 Cell Therapy in Adults With Advanced Heart Failure Undergoing Heart Bypass Surgery
NCT07646210Advanced Heart Failure, Ischemic Heart Failure
HELP Therapeutics Co., Ltd.
Phase 1/2
12
Texas
2026-09
Not yet open
Evaluation of Protein Loading on Measurement of Renal Reserve
NCT07335614Glomerular Filtration Rate
MediBeacon
Not applicable
25
Vermont
2026-09
Not yet open
Closed-Loop Transcranial Alternating Current Stimulation for the Treatment of Major Depressive Disorder
NCT07282678Depression - Major Depressive Disorder, Transcranial Alternating Current Stimulation
Pulvinar Neuro, LLC
Not applicable
214
North Carolina
2026-09
Recruiting
Endo-SPONGE for Treatment of Anastomotic or Hartmann's Stump Leakages in Lower Pelvic Area
NCT07035431Anastomotic Leaks, Hartmanns Stump Leakage
Boston Scientific Corporation
Not applicable
66
California, Florida, Massachusetts, New York, Ohio, Pennsylvania, Washington, West Virginia
2026-09
Not yet open
A Master Protocol Studying Multiple Amyloid-Targeting Therapies in Healthy Participants and Participants With Alzheimer's Disease
NCT07787169Alzheimer Disease, Amyloid, Plaque, Amyloid, Healthy Volunteers
Eli Lilly and Company
Phase 1
179
California, Florida, Georgia, Michigan
2026-09
Not yet open
A Study of Eloralintide (LY3841136) in Female Participants With Obesity or Overweight
NCT07808060Obesity, Overweight
Eli Lilly and Company
Phase 1
34
Florida, Texas
2026-09
Not yet open
A Study of IOV-5001 in Adults With Advanced Solid Tumors
NCT07743723Advanced Solid Tumors, Non-Small Cell Lung Cancer, Triple Negative Breast Cancer (TNBC), Colorectal Cancer
Iovance Biotherapeutics, Inc.
Phase 1/2
106
New York
2026-09
Recruiting
An AAV Gene Therapy Trial of AFTX-201 in Adults With BAG3-Associated Dilated Cardiomyopathy (DCM)
NCT07426419Dilated Cardiomyopathy (DCM), BAG3 Mutation Associated Dilated Cardiomyopathy
Affinia Therapeutics
Phase 1/2
22
Florida, Missouri, Texas
2026-09
Recruiting
A Study to Investigate PORT-77 Oral Dosing Compared With Placebo in Participants With Erythropoietic Protoporphyria (EPP) or X-linked Protoporphyria (XLP)
NCT07820085Erythropoietic Protoporphyria (EPP), X-Linked Protoporphyria (XLP), EPP2
Portal Therapeutics, Inc.
Phase 2/3
225
California, Ohio
2026-09
Recruiting
Study of d-MAPPSโ„ข Ophthalmic Solution in Adults With Chronic Ocular Graft-Versus-Host Disease (oGVHD)
NCT07776210oGVHD, Ocular Graft Versus Host Disease
Regenerative Ocular Immunobiologics LLC
Phase 3
30
California, Florida, Massachusetts
2026-09
Recruiting
A Study to Evaluate the Efficacy, PK, Safety, and Tolerability of VIM0423 in Adults With Parkinson's Disease Tremor Insufficiently Responsive to Dopaminergic Therapy
NCT07804615PARKINSON DISEASE (Disorder)
Vima Therapeutics
Phase 2
80
Arizona, California, Connecticut, Florida, Georgia, Kansas, Maryland, Michigan
2026-09
Not yet open
A Study of LY4329090 in Participants With Obesity or Overweight Who Are Otherwise Healthy
NCT07808073Obesity, Overweight
Eli Lilly and Company
Phase 1
184
Florida, Texas
2026-09
Not yet open
A Study of Inhaled Treprostinil (LIQ861) in Adults With Pulmonary Arterial Hypertension Transitioning From Oral Selexipag
NCT07759804Pulmonary Arterial Hypertension (PAH)
Liquidia Technologies, Inc.
Phase 4
20
Georgia
2026-09
Recruiting
REC-7735 in Participants With Solid Tumors
NCT07819136Solid Tumors
Recursion Pharmaceuticals Inc.
Phase 1/2
90
Michigan, Texas, Virginia
2026-09
Not yet open
Evaluation of Two Monthly Silicone Hydrogel Multifocal Toric in Soft Contact Lens Wearers
NCT07829419Astigmatism, Myopia
CooperVision International Limited (CVIL)
Not applicable
60
New York, Ohio, Texas
2026-09
By invitation
VitaSmart HOPE System: Bridge to HOPE Registry
NCT07578441End Stage Liver DIsease, Liver Failure
Bridge to Life Ltd.
Observational
5,000
Ohio
2026-09
Recruiting
Redefine Study: A Study Evaluating the Efficacy, Safety, and Tolerability of COMP360 in Participants With Post-traumatic Stress Disorder
NCT07570654PTSD - Post Traumatic Stress Disorder, PTSD, PTSD Symptoms, PTSD, Post Traumatic Stress Disorder
COMPASS Pathways
Phase 2/3
300
Florida, New York
2026-09
Not yet open
A Study of Tirzepatide (LY3298176) in Participants With Type 1 Diabetes Mellitus and Overweight or Obesity
NCT07803744Diabetes Mellitus, Type 1, Overweight, Obesity
Eli Lilly and Company
Phase 1
18
Florida
2026-09
Not yet open
Reduction of Depression Through Dual Treatment: Digital CBT & NBHWC Coaching
NCT07195292Hearing Disability, Depression, Mobility Disability
Toivoa Inc
Not applicable
200
Delaware, New Jersey, Ohio, Texas
2026-09
Not yet open
BAFF CAR-T Cells (LMY-922) for Treatment of Refractory Hematologic Malignancies
NCT07679919Non-Hodgkin Lymphoma, Chronic Lymphocytic Leukemia, Hairy Cell Leukemia, Multiple Myeloma
Luminary Therapeutics
Phase 1
27
Ohio
2026-09
Not yet open
Study of Zola-cel (BMS-986353), in Participants With Autoimmune Cytopenia (Breakfree-AiCE)
NCT07603557Chronic Immune Thrombocytopenia, Autoimmune Hemolytic Anemia
Juno Therapeutics, Inc., a Bristol-Myers Squibb Company
Phase 2
52
Massachusetts, Texas, Washington
2026-08-31
Recruiting
Phase 1 Study Involving SAB01 and Healthy Participants
NCT07815561Healthy Adult Participants
Santa Ana Bio
Phase 1
88
California
2026-08-31
Recruiting
Impact of Fluciclovine (18F) PET (Positron Emission Tomography) on the Management of Prostate Cancer Following Negative or Equivocal PSMA (Prostate-Specific Membrane Antigen) PET Imaging at the Time of Biochemical Recurrence
NCT07569926Prostate Cancer
Blue Earth Diagnostics
Phase 4
142
California, Georgia, Massachusetts, Missouri, Oregon, Texas
2026-08-31
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Priya Life Science (2026). Clinical trial register: industry-sponsored studies with a US investigative site. Derived from ClinicalTrials.gov. Retrieved 23 September 2026. https://priyalifescience.com/clinical-trials-usa?page=3

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