MK-8527 clinical trials
MK-8527 is named as an intervention in 2 current clinical trials in our USA, France, Netherlands, Switzerland, Brazil and Australia registers. None are recruiting at the moment. The most common phase is Phase 3. The lead sponsor is Merck Sharp & Dohme LLC. The most-studied condition is Human Immunodeficiency Virus (HIV).
Patient leaflets for MK-8527
The package leaflet is the official guide for patients that comes with every medicine. These links go to the regulators that publish it.
- UKUnited Kingdom: Search MHRA ProductsPatient information leaflets and SmPCs for UK-licensed products.
- USUnited States: Search DailyMedFDA-approved labels, including patient and medication guides.
Leaflets differ between brands and countries; always read the one that comes with your own medicine. This is regulatory information, not medical advice.
Trials by status
Trials by phase
Clinical trials of MK-8527
2 trials| Study | Phase | Status | Lead sponsor | Registers |
|---|---|---|---|---|
|
A Clinical Study of MK-8527 to Prevent Human Immunodeficiency Virus Type 1 (HIV-1) (MK-8527-011)
NCT07044297 · Human Immunodeficiency Virus (HIV), HIV Pre-Exposure Prophylaxis
|
Phase 3 | Active, closed | Merck Sharp & Dohme LLC | USA, France, Netherlands, Switzerland, Brazil, Australia |
|
A Clinical Study of MK-8527 in Healthy Participants (MK-8527-021)
NCT07661108 · Healthy
|
Phase 1 | Active, closed | Merck Sharp & Dohme LLC | USA |
Registers list studies that are recruiting, about to open, active but closed to enrolment, or enrolling by invitation. The UK and USA registers cover industry-sponsored studies only. Trial titles and statuses are copied from the registry as published.
Conditions studied with MK-8527
3 conditionsSponsors
lead sponsor per trial| Lead sponsor | Trials |
|---|---|
| Merck Sharp & Dohme LLC | 2 |
By country register
| Register | Trials | Recruiting |
|---|---|---|
| Clinical trials in USA | 2 | 0 |
| Clinical trials in France | 1 | 0 |
| Clinical trials in Netherlands | 1 | 0 |
| Clinical trials in Switzerland | 1 | 0 |
| Clinical trials in Brazil | 1 | 0 |
| Clinical trials in Australia | 1 | 0 |
A trial with sites in more than one country appears in each of those registers.
Related compounds
Questions about MK-8527 trials
How many clinical trials are testing MK-8527?
2 current trials in our USA, France, Netherlands, Switzerland, Brazil and Australia registers name MK-8527 as a drug or biological intervention, as of the registry sync on 9 November 2026. Completed and withdrawn studies are not counted.
Are MK-8527 trials recruiting patients?
Not at the moment. None of the 2 trials in our registers is recruiting; they are active but closed to enrolment, not yet open, or enrolling by invitation. Only the study team can confirm whether a patient is eligible.
Who sponsors MK-8527 clinical trials?
The lead sponsor is Merck Sharp & Dohme LLC. The number in brackets is how many trials each organisation leads.
Where does this information come from?
Every trial, status, phase and sponsor on this page is copied from public ClinicalTrials.gov records by a daily sync. Nothing here describes how MK-8527 works or whether it is effective, and it is not medical advice.
How this page is built
Everything on this page is copied from public ClinicalTrials.gov registry records — it is not written from memory, and nothing here describes how MK-8527 works or whether it is effective. Each trial links to its own record so you can check it yourself.
- ClinicalTrials.gov (U.S. National Library of Medicine) ↗ Trial IDs, titles, intervention names and synonyms, phase, overall status, lead sponsor and conditions for every trial on this page
This page is built automatically: a daily sync job reads the registry records behind our country trial registers, collects every trial that lists MK-8527 (or a registered synonym) as a drug or biological intervention, and tabulates the registry fields directly. Placebos and generic comparators are excluded. There is no AI drafting and no per-compound editorial pass, and the page has not been clinically reviewed. The “last verified” date above is the timestamp of that sync, not a review date. Our general editorial approach is described in our editorial standards and corrections policy. The ClinicalTrials.gov data on this page was last retrieved on 9 Nov 2026. How every register is built: methodology · fixes we have made: corrections log.