Lepodisiran clinical trials
Lepodisiran is named as an intervention in 2 current clinical trials in our UK, USA, Spain, Netherlands, Czechia, Australia, India, China, Germany, France, Italy, Belgium, Denmark, Poland, Austria, Canada, Brazil, Mexico, Japan, South Korea, Taiwan and Israel registers. 1 is recruiting patients now. All registered phases are Phase 3. The lead sponsor is Eli Lilly and Company. The most-studied condition is Atherosclerosis.
Patient leaflets for Lepodisiran
The package leaflet is the official guide for patients that comes with every medicine. These links go to the regulators that publish it.
- UKUnited Kingdom: Search MHRA ProductsPatient information leaflets and SmPCs for UK-licensed products.
- USUnited States: Search DailyMedFDA-approved labels, including patient and medication guides.
Leaflets differ between brands and countries; always read the one that comes with your own medicine. This is regulatory information, not medical advice.
Trials by status
Trials by phase
Clinical trials of Lepodisiran
2 trials| Study | Phase | Status | Lead sponsor | Registers |
|---|---|---|---|---|
|
A Study to See if Lepodisiran Can Reduce Plaque in Coronary Arteries of Adults With Elevated Lp(a) Who Have Had Heart Events or Are at High Risk
NCT07613294 · Atherosclerosis, Cardiovascular Diseases, Lipoprotein(a)
|
Phase 3 | Recruiting | Eli Lilly and Company | UK, USA, Spain, Netherlands, Czechia, Australia |
|
A Study to Investigate the Effect of Lepodisiran on the Reduction of Major Adverse Cardiovascular Events in Adults With Elevated Lipoprotein(a) - ACCLAIM-Lp(a)
NCT06292013 · Atherosclerotic Cardiovascular Disease (ASCVD), Elevated Lp(a)
|
Phase 3 | Active, closed | Eli Lilly and Company | UK, USA, India, China, Germany, France, Spain, Italy, Netherlands, Belgium, Denmark, Poland, Austria, Czechia, Canada, Brazil, Mexico, Japan, South Korea, Taiwan, Australia, Israel |
Registers list studies that are recruiting, about to open, active but closed to enrolment, or enrolling by invitation. The UK and USA registers cover industry-sponsored studies only. Trial titles and statuses are copied from the registry as published.
Conditions studied with Lepodisiran
5 conditionsSponsors
lead sponsor per trial| Lead sponsor | Trials |
|---|---|
| Eli Lilly and Company | 2 |
By country register
A trial with sites in more than one country appears in each of those registers.
Related compounds
Questions about Lepodisiran trials
How many clinical trials are testing Lepodisiran?
2 current trials in our UK, USA, Spain, Netherlands, Czechia, Australia, India, China, Germany, France, Italy, Belgium, Denmark, Poland, Austria, Canada, Brazil, Mexico, Japan, South Korea, Taiwan and Israel registers name Lepodisiran (also registered as LY3819469) as a drug or biological intervention, as of the registry sync on 9 November 2026. Completed and withdrawn studies are not counted.
Are Lepodisiran trials recruiting patients?
Yes. 1 of the 2 trials is recruiting: 1 with sites in UK, 1 with sites in USA, 1 with sites in Spain, 1 with sites in Netherlands, 1 with sites in Czechia and 1 with sites in Australia. Eligibility and site contacts are on each trial's record. Only the study team can confirm whether a patient is eligible.
Who sponsors Lepodisiran clinical trials?
The lead sponsor is Eli Lilly and Company. The number in brackets is how many trials each organisation leads.
Where does this information come from?
Every trial, status, phase and sponsor on this page is copied from public ClinicalTrials.gov records by a daily sync. Nothing here describes how Lepodisiran works or whether it is effective, and it is not medical advice.
How this page is built
Everything on this page is copied from public ClinicalTrials.gov registry records — it is not written from memory, and nothing here describes how Lepodisiran works or whether it is effective. Each trial links to its own record so you can check it yourself.
- ClinicalTrials.gov (U.S. National Library of Medicine) ↗ Trial IDs, titles, intervention names and synonyms, phase, overall status, lead sponsor and conditions for every trial on this page
This page is built automatically: a daily sync job reads the registry records behind our country trial registers, collects every trial that lists Lepodisiran (or a registered synonym) as a drug or biological intervention, and tabulates the registry fields directly. Placebos and generic comparators are excluded. There is no AI drafting and no per-compound editorial pass, and the page has not been clinically reviewed. The “last verified” date above is the timestamp of that sync, not a review date. Our general editorial approach is described in our editorial standards and corrections policy. The ClinicalTrials.gov data on this page was last retrieved on 9 Nov 2026. How every register is built: methodology · fixes we have made: corrections log.