Lepodisiran is named as an intervention in 2 current clinical trials in our UK, USA, India and China registers. 1 is recruiting patients now. All registered phases are Phase 3. The lead sponsor is Eli Lilly and Company. The most-studied condition is Atherosclerosis.
| Study | Phase | Status | Lead sponsor | Registers |
|---|---|---|---|---|
|
A Study to See if Lepodisiran Can Reduce Plaque in Coronary Arteries of Adults With Elevated Lp(a) Who Have Had Heart Events or Are at High Risk
NCT07613294 · ClinicalTrials.gov ↗ · Atherosclerosis, Cardiovascular Diseases, Lipoprotein(a)
|
Phase 3 | Recruiting | Eli Lilly and Company | UK, USA |
|
A Study to Investigate the Effect of Lepodisiran on the Reduction of Major Adverse Cardiovascular Events in Adults With Elevated Lipoprotein(a) - ACCLAIM-Lp(a)
NCT06292013 · ClinicalTrials.gov ↗ · Atherosclerotic Cardiovascular Disease (ASCVD), Elevated Lp(a)
|
Phase 3 | Active, closed | Eli Lilly and Company | UK, USA, India, China |
Registers list studies that are recruiting, about to open, active but closed to enrolment, or enrolling by invitation. The UK and USA registers cover industry-sponsored studies only. Trial titles and statuses are copied from the registry as published.
| Lead sponsor | Trials |
|---|---|
| Eli Lilly and Company | 2 |
| Register | Trials | Recruiting |
|---|---|---|
| Clinical trials in UK | 2 | 1 |
| Clinical trials in USA | 2 | 1 |
| Clinical trials in India | 1 | 0 |
| Clinical trials in China | 1 | 0 |
A trial with sites in more than one country appears in each of those registers.
2 current trials in our UK, USA, India and China registers name Lepodisiran (also registered as LY3819469) as a drug or biological intervention, as of the registry sync on 25 September 2026. Completed and withdrawn studies are not counted.
Yes. 1 of the 2 trials is recruiting: 1 with sites in UK and 1 with sites in USA. Eligibility and site contacts are on each trial's record. Only the study team can confirm whether a patient is eligible.
The lead sponsor is Eli Lilly and Company. The number in brackets is how many trials each organisation leads.
Every trial, status, phase and sponsor on this page is copied from public ClinicalTrials.gov records by a daily sync. Nothing here describes how Lepodisiran works or whether it is effective, and it is not medical advice.
Everything on this page is copied from public ClinicalTrials.gov registry records — it is not written from memory, and nothing here describes how Lepodisiran works or whether it is effective. Each trial links to its own record so you can check it yourself.
This page is built automatically: a daily sync job reads the registry records behind our country trial registers, collects every trial that lists Lepodisiran (or a registered synonym) as a drug or biological intervention, and tabulates the registry fields directly. Placebos and generic comparators are excluded. There is no AI drafting and no per-compound editorial pass, and the page has not been clinically reviewed. The “last verified” date above is the timestamp of that sync, not a review date. Our general editorial approach is described in our editorial standards and corrections policy. The ClinicalTrials.gov data on this page was last retrieved on 25 Sep 2026.