VERVE-102 is named as an intervention in 2 current clinical trials in our USA and UK registers. 1 is recruiting patients now. The most common phase is Phase 1. The lead sponsor is Verve Therapeutics, Inc. The most-studied condition is Heterozygous Familial Hypercholesterolemia.
| Study | Phase | Status | Lead sponsor | Registers |
|---|---|---|---|---|
|
A Study of VERVE-102 in Patients With Familial Hypercholesterolemia or Premature Coronary Artery Disease
NCT06164730 · ClinicalTrials.gov ↗ · Heterozygous Familial Hypercholesterolemia, Premature Coronary Heart Disease
|
Phase 1 | Recruiting | Verve Therapeutics, Inc. | UK, USA |
|
A Study of VERVE-102 (LY4636581) in Adults With or at High Risk for Cardiovascular Disease
NCT07839936 · Atherosclerosis, Cardiovascular Disease, Hypercholesterolemia
|
Phase 2 | Not yet open | Verve Therapeutics, Inc. | USA |
Registers list studies that are recruiting, about to open, active but closed to enrolment, or enrolling by invitation. The UK and USA registers cover industry-sponsored studies only. Trial titles and statuses are copied from the registry as published.
| Lead sponsor | Trials |
|---|---|
| Verve Therapeutics, Inc. | 2 |
| Register | Trials | Recruiting |
|---|---|---|
| Clinical trials in USA | 2 | 1 |
| Clinical trials in UK | 1 | 1 |
A trial with sites in more than one country appears in each of those registers.
2 current trials in our USA and UK registers name VERVE-102 (also registered as LY4636581) as a drug or biological intervention, as of the registry sync on 25 September 2026. Completed and withdrawn studies are not counted.
Yes. 1 of the 2 trials is recruiting: 1 with sites in USA and 1 with sites in UK. Eligibility and site contacts are on each trial's record. Only the study team can confirm whether a patient is eligible.
The lead sponsor is Verve Therapeutics, Inc. The number in brackets is how many trials each organisation leads.
Every trial, status, phase and sponsor on this page is copied from public ClinicalTrials.gov records by a daily sync. Nothing here describes how VERVE-102 works or whether it is effective, and it is not medical advice.
Everything on this page is copied from public ClinicalTrials.gov registry records — it is not written from memory, and nothing here describes how VERVE-102 works or whether it is effective. Each trial links to its own record so you can check it yourself.
This page is built automatically: a daily sync job reads the registry records behind our country trial registers, collects every trial that lists VERVE-102 (or a registered synonym) as a drug or biological intervention, and tabulates the registry fields directly. Placebos and generic comparators are excluded. There is no AI drafting and no per-compound editorial pass, and the page has not been clinically reviewed. The “last verified” date above is the timestamp of that sync, not a review date. Our general editorial approach is described in our editorial standards and corrections policy. The ClinicalTrials.gov data on this page was last retrieved on 25 Sep 2026.