Dextromethorphan is named as an intervention in 3 current clinical trials in our UK, USA, Germany, Belgium, Poland, Canada and Australia registers. 2 are recruiting patients now. The most common phase is Phase 1. The sponsor with the most trials is Hoffmann-La Roche (1). The most-studied condition is Active Ulcerative Colitis.
| Study | Phase | Status | Lead sponsor | Registers |
|---|---|---|---|---|
|
A Study Investigating the Change in Metabolism Phenotype in Paediatric, Adolescent & Young Adults With Hodgkin or Non-Hodgkin Lymphoma.
NCT06383338 · ClinicalTrials.gov ↗ · Hodgkin Lymphoma, Non Hodgkin Lymphoma
|
Phase 1 | Recruiting | Murdoch Childrens Research Institute | Australia |
|
An Early-Stage Study in Multiple Clinics of How Afimkibart May Affect the Body's Processing of Medicines That Rely on Cytochrome P450 Enzymes in Participants With Ulcerative Colitis
NCT07665723 · ClinicalTrials.gov ↗ · Active Ulcerative Colitis
|
Phase 1 | Recruiting | Hoffmann-La Roche | UK, USA, Germany, Belgium, Poland |
|
Pharmacological Mechanisms of Low-intensity Focused Ultrasound for Motor Cortex Neuroplasticity
NCT04923659 · ClinicalTrials.gov ↗ · Low Intensity Focussed Ultrasound
|
Phase EARLY_PHASE1 | Active, closed | University Health Network, Toronto | Canada |
Registers list studies that are recruiting, about to open, active but closed to enrolment, or enrolling by invitation. The UK and USA registers cover industry-sponsored studies only. Trial titles and statuses are copied from the registry as published.
The same active substance in our other registers, matched by its exact name. Each entry links to the register record it comes from.
2 single-substance products containing Dextromethorphan on the HPRA medicines list.
No entry for Dextromethorphan in the EMA, FDA or German BfArM shortage lists we track.
| Lead sponsor | Trials |
|---|---|
| Hoffmann-La Roche | 1 |
| University Health Network, Toronto | 1 |
| Murdoch Childrens Research Institute | 1 |
| Register | Trials | Recruiting |
|---|---|---|
| Clinical trials in UK | 1 | 1 |
| Clinical trials in USA | 1 | 1 |
| Clinical trials in Germany | 1 | 1 |
| Clinical trials in Belgium | 1 | 1 |
| Clinical trials in Poland | 1 | 1 |
| Clinical trials in Canada | 1 | 0 |
| Clinical trials in Australia | 1 | 1 |
A trial with sites in more than one country appears in each of those registers.
3 current trials in our UK, USA, Germany, Belgium, Poland, Canada and Australia registers name Dextromethorphan as a drug or biological intervention, as of the registry sync on 26 September 2026. Completed and withdrawn studies are not counted.
Yes. 2 of the 3 trials are recruiting: 1 with sites in UK, 1 with sites in USA, 1 with sites in Germany, 1 with sites in Belgium, 1 with sites in Poland and 1 with sites in Australia. Eligibility and site contacts are on each trial's record. Only the study team can confirm whether a patient is eligible.
Hoffmann-La Roche (1), University Health Network, Toronto (1) and Murdoch Childrens Research Institute (1). The number in brackets is how many trials each organisation leads.
Yes. The HPRA medicines list includes 2 single-substance products containing Dextromethorphan, for example Benylin Non-Drowsy Dry Coughs, Syrup Dextromethorphan hydrobromide 7.5 mg/5 ml (JNTL Consumer Health (Ireland) Limited). A licence does not mean a product is currently marketed or reimbursed; see each product's record.
Not in the lists we track: Dextromethorphan has no entry in the EMA, FDA or German BfArM shortage registers as of their latest sync.
Every trial, status, phase and sponsor on this page is copied from public ClinicalTrials.gov records by a daily sync. Nothing here describes how Dextromethorphan works or whether it is effective, and it is not medical advice.
Everything on this page is copied from public ClinicalTrials.gov registry records — it is not written from memory, and nothing here describes how Dextromethorphan works or whether it is effective. Each trial links to its own record so you can check it yourself.
This page is built automatically: a daily sync job reads the registry records behind our country trial registers, collects every trial that lists Dextromethorphan (or a registered synonym) as a drug or biological intervention, and tabulates the registry fields directly. Placebos and generic comparators are excluded. There is no AI drafting and no per-compound editorial pass, and the page has not been clinically reviewed. The “last verified” date above is the timestamp of that sync, not a review date. Our general editorial approach is described in our editorial standards and corrections policy. The ClinicalTrials.gov data on this page was last retrieved on 26 Sep 2026.