Esketamine is named as a drug or biological intervention in 27 clinical trials in our China and USA trial registers, 11 of which are recruiting. Lead sponsors include Peking University First Hospital (3), Tianjin Medical University General Hospital (3) and Janssen Research & Development, LLC (2). Registered phases: Not applicable, Phase 4, Phase 3 and Phase EARLY_PHASE1. Conditions studied include Dexmedetomidine; Esketamine; Anesthesia.
Registers list studies that are recruiting, about to open, active but closed to enrolment, or enrolling by invitation. The UK and USA registers cover industry-sponsored studies only. Trial titles and statuses are copied from the registry as published.
| Condition (as registered) | Trials |
|---|---|
| Dexmedetomidine | 4 |
| Esketamine | 4 |
| Anesthesia | 2 |
| Ketamine | 2 |
| Depressive Disorder, Major | 1 |
| Depressive Disorder, Treatment-Resistant | 1 |
| Delirium in Old Age | 1 |
| Delirium, Postoperative | 1 |
| Cognitive Dysfunction | 1 |
| General Anesthesia | 1 |
| Surgery | 1 |
| Depressed | 1 |
| Bariatric Surgery | 1 |
| Sleep Disturbance | 1 |
| Circadian Rhythm | 1 |
| Postoperative Sleep Disturbance | 1 |
| Electroencephalogram (EEG) | 1 |
| Delirium - Postoperative | 1 |
| Opioid-Free Anaesthesia | 1 |
| Preoperative Anxiety | 1 |
| Preoperative Sedation | 1 |
| Children | 1 |
| Hip Fractures | 1 |
| Behavior Problem | 1 |
| Quality of Postoperative Recovery | 1 |
| Cholestatic Pruritus | 1 |
| Scoliosis Correction | 1 |
| Postoperative Analgesia | 1 |
| Postherpetic Neuralgia | 1 |
| Esketamine Plus Dexmedetomidine Affect Postoperative Quality | 1 |
| Thoracoscopy | 1 |
| Lung Neoplasms | 1 |
| Fibromyalgia | 1 |
| Pregabalin | 1 |
| Perioperative Neurocognitive Disorders | 1 |
| Senile Pruritus | 1 |
| Prenatal Depression | 1 |
| Postpartum Depression | 1 |
| Insomnia | 1 |
| Breast Cancer Surgery | 1 |
+ 11 more conditions in the trial records above.
| Lead sponsor | Trials |
|---|---|
| Peking University First Hospital | 3 |
| Tianjin Medical University General Hospital | 3 |
| Janssen Research & Development, LLC | 2 |
| Beijing Tiantan Hospital | 2 |
| Nanfang Hospital, Southern Medical University | 1 |
| The First Hospital of Jilin University | 1 |
| Zhuan Zhang | 1 |
| Fudan University | 1 |
| Qianfoshan Hospital | 1 |
| Second Affiliated Hospital of Wenzhou Medical University | 1 |
| Peking University Shenzhen Hospital | 1 |
| Nanjing Children's Hospital | 1 |
| Northern Jiangsu People's Hospital | 1 |
| First Affiliated Hospital of Kunming Medical University | 1 |
| Xijing Hospital | 1 |
| Nanjing First Hospital, Nanjing Medical University | 1 |
| The First Affiliated Hospital with Nanjing Medical University | 1 |
| Second Affiliated Hospital of Nanchang University | 1 |
| Second Affiliated Hospital, Zhejiang University, School of Medicine | 1 |
| The Second Hospital of Anhui Medical University | 1 |
| Chinese PLA General Hospital | 1 |
| Register | Esketamine trials |
|---|---|
| Clinical trials in China | 25 |
| Clinical trials in USA | 2 |
A trial with sites in more than one country appears in each of those registers.
Everything on this page is copied from public ClinicalTrials.gov registry records — it is not written from memory, and nothing here describes how Esketamine works or whether it is effective. Each trial links to its own record so you can check it yourself.
This page is built automatically: a daily sync job reads the registry records behind our country trial registers, collects every trial that lists Esketamine (or a registered synonym) as a drug or biological intervention, and tabulates the registry fields directly. Placebos and generic comparators are excluded. There is no AI drafting and no per-compound editorial pass, and the page has not been clinically reviewed. The “last verified” date above is the timestamp of that sync, not a review date. Our general editorial approach is described in our editorial standards and corrections policy. The ClinicalTrials.gov data on this page was last retrieved on 24 Sep 2026.