Evaluate the Safety and Feasibility of Same-Day Bilateral Epithelium-On Corneal Cross-Linking for Keratoconus

NCT07629557 · tracked via the Priya Life Science USA tracker

Sponsor

Glaukos Corporation

Phase

Phase 4

Started

2026-05-11

Last updated

2026-06-05

Condition(s) studied

Keratoconus

Investigational drug(s) / intervention(s)

Riboflavin Ophthalmic SolutionsUV-A Irradiation System

Riboflavin Ophthalmic Solutions: Riboflavin Ophthalmic Solutions

UV-A Irradiation System: O2n UV-A Irradiation System

Study summary

Clinical trial to evaluate the safety and feasibility of corneal cross-linking in both eyes on the same day in subjects with keratoconus.

Eligibility

Sex

ALL

Min age

13 Years

Max age

—

Healthy volunteers

Inclusion Criteria: * Provide written informed consent * Willing and able to comply with study instructions and follow-up visits * Diagnosis of keratoconus in each eye Exclusion Criteria: * Known allergy or sensitivity to study medications * History of corneal disease * Prior corneal cross-linking in either eye * Pregnant, nursing, or planning pregnancy during the study period * Participated in other investigational drug or device trial within 30 days of the study

Primary outcome measure(s)

Successful completion of bilateral epithelium-on corneal collagen cross-linking. — Approximately 2.5 Months
Portion of subjects that the Investigator completed bilateral epithelium-on corneal collagen cross-linking treatment on the same day.

Trial sites (1)

Facility	City	Region	Status
Glaukos Investigative Site	Westerville	Ohio	Recruiting

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Other trials for the same condition

Assessing Patient Engagement in Keratoconus Clinical Research Starting soon

McNeel Eye Center Corneal Crosslinking Study Active, not recruiting

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Official registry record

This page summarises publicly available registry data for informational purposes — not medical advice. Eligibility is determined by each study team; patients should discuss participation with their clinician.

View NCT07629557 on ClinicalTrials.gov ↗ ← All trials in the USA