McNeel Eye Center Corneal Crosslinking Study

Condition(s) studied

Investigational drug(s) / intervention(s)

Crosslinking using UV light of two different fluence rates: The treatment of keratoconus involves the application of riboflavin followed by Ultraviolet light of differing intensities. This study will determine the effectiveness of a greater UV light fluence at a shorter treatment time than is currently utilized.

Study summary

This study will investigate the effectiveness in treating keratoconus, pellucid marginal degeneration and post LASIK iatrogenic ectasia utilizing fluence rates and treatment times of Corneal Cross Linking other than the original FDA approved protocol of 3mw/cm2.

Eligibility

Primary outcome measure(s)

• Post treatment topographic analysis of Crosslinked patients — One Year
  Pre-treatment videokeratography will be compared to post treatment keratography at certain intervals up to one year. Overall flattening of corneal curvature will be a primary study item.

Trial sites (1)

Other trials for the same condition