Ireland
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Priya Life Science Compound trial record
Compound · clinical trials

Cenvacibart clinical trials

Also listed in trial records as REGN7508
Source: ClinicalTrials.gov, U.S. National Library of Medicine — the 9 trials in our USA, Japan, Canada, Israel, UK, Spain, Poland, Brazil, South Korea and Belgium registers that name Cenvacibart as an intervention. Synced 10 Nov 2026
9Current trials
9Recruiting now
1Lead sponsor
10Country registers
At a glance

Cenvacibart is named as an intervention in 9 current clinical trials in our USA, Japan, Canada, Israel, UK, Spain, Poland, Brazil, South Korea and Belgium registers. 9 are recruiting patients now. The most common phase is Phase 3. The lead sponsor is Regeneron Pharmaceuticals. The most-studied condition is Atrial Fibrillation (AF). The EU clinical trials register (CTIS) separately lists 5 authorised or ongoing trials.

Patient leaflets for Cenvacibart

The package leaflet is the official guide for patients that comes with every medicine. These links go to the regulators that publish it.

  • UK
    United Kingdom: Search MHRA Products
    Patient information leaflets and SmPCs for UK-licensed products.
  • US
    United States: Search DailyMed
    FDA-approved labels, including patient and medication guides.

Leaflets differ between brands and countries; always read the one that comes with your own medicine. This is regulatory information, not medical advice.

Trials by status

  • Recruiting9100%

Trials by phase

  • Phase 3778%
  • Phase 2111%
  • Phase 1111%
01

Clinical trials of Cenvacibart

9 trials
StudyPhaseStatusLead sponsorRegisters
REGN7508 Versus Apixaban and Enoxaparin for Thromboprophylaxis After Total Knee Arthroplasty in Adults
NCT07015905 · Venous Thromboembolism (VTE)
Phase 3 Recruiting Regeneron Pharmaceuticals USA, Poland, Japan
REGN7508 Versus Acetylsalicylic Acid (ASA) for Venous Thromboprophylaxis After Total Knee Arthroplasty in Adult Participants
NCT07213778 · Symptomatic Venous Thromboembolism (VTE)
Phase 3 Recruiting Regeneron Pharmaceuticals USA, Spain
Reducing Adverse Vascular Outcomes With Factor XI Inhibition in Adult Participants With Peripheral Artery Disease
NCT07318610 · Peripheral Artery Disease (PAD)
Phase 3 Recruiting Regeneron Pharmaceuticals UK, USA
REGN7508 in Adult Participants for Prevention of Cancer-Associated Thrombosis
NCT07410117 · Cancer-Associated Thrombosis (CAT)
Phase 3 Recruiting Regeneron Pharmaceuticals USA, Japan, Israel
Stroke and Systemic Embolism Prevention in Adult Participants With Atrial Fibrillation for Whom Oral Anticoagulation is Unsuitable
NCT07430956 · ClinicalTrials.gov ↗ · Atrial Fibrillation (AF)
Phase 3 Recruiting Regeneron Pharmaceuticals USA, Canada
Treatment and Secondary Prevention of Venous Thromboembolism (VTE) in Adult Participants With Solid and Hematologic Cancers
NCT07493304 · Venous Thromboembolism (VTE)
Phase 3 Recruiting Regeneron Pharmaceuticals USA, Japan, South Korea
Stroke and Systemic Embolism Prevention in Adult Participants With Atrial Fibrillation
NCT07626411 · Atrial Fibrillation (AF)
Phase 3 Recruiting Regeneron Pharmaceuticals USA, Canada, Japan
Safety in Adult Participants With Atrial Fibrillation Who Are Treated With Anticoagulation
NCT07175428 · Atrial Fibrillation (AF)
Phase 2 Recruiting Regeneron Pharmaceuticals USA, Canada, Brazil, Israel
Study of 3 Monoclonal Antibodies (REGN9933, REGN7508, and REGN9533) in Adult Participants With End-Stage Kidney Disease on Hemodialysis
NCT07759167 · ClinicalTrials.gov ↗ · End-Stage Kidney Disease (ESKD)
Phase 1 Recruiting Regeneron Pharmaceuticals Belgium

Registers list studies that are recruiting, about to open, active but closed to enrolment, or enrolling by invitation. The UK and USA registers cover industry-sponsored studies only. Trial titles and statuses are copied from the registry as published.

02

Cenvacibart in the EU trials register (CTIS)

5 trials

Authorised or ongoing trials in the EU Clinical Trials Information System that list a product containing Cenvacibart. Many trials are registered in both CTIS and ClinicalTrials.gov, so these are shown separately rather than added to the count above. Trials with a site in Ireland are listed first.

StudyPhaseStatusSponsorCountries
A Phase 3, Randomized, Multicenter, Double-blind Study to Assess Stroke and Systemic Embolism Prevention with REGN7508, a Monoclonal Antibody Against Factor XI, Versus Apixaban in Participants with Atrial Fibrillation (ROXI-EVEREST)
2025-521617-97-00 · Cardiovascular Diseases
Phase 3 Authorised Regeneron Pharmaceuticals Inc Portugal, Germany, Italy + 12 more
A Master Protocol for a Phase 3, Randomized, Multicenter, Double-blind Study to Assess Stroke and Systemic Embolism Prevention with REGN7508 and REGN9933, Monoclonal Antibodies Against Factor XI, versus Placebo in Participants with Atrial Fibrillation for Whom Oral Anticoagulation is Unsuitable (ROXI-INCLINE)
2025-521618-25-00 · Cardiovascular Diseases
Phase 3 Authorised Regeneron Pharmaceuticals Inc Spain, Bulgaria, Hungary + 8 more
A Master Protocol for a Phase 3, Multicenter, Randomized Study to Evaluate the Efficacy and Safety of REGN7508 and REGN9933, Monoclonal Antibodies Against Factor XI, in Participants with Recent Lower Extremity Revascularization for Symptomatic Peripheral Artery Disease (ROXI-PALISADE)
2025-522954-37-00 · Hemic and Lymphatic Diseases
Phase 3 Authorised Regeneron Pharmaceuticals Inc Spain, Slovakia, Hungary + 16 more
A Phase 3, Multicenter, Randomized, Double-Blind, Placebo-Controlled Study to Assess Efficacy and Safety of REGN7508, a Monoclonal Antibody Against FXI, for Primary Prophylaxis of Cancer-Associated Thrombosis for Participants with Solid Tumors Undergoing Cancer Treatment (ROXI-CAT-I)
2024-519298-21-00 · CTIS ↗ · Cardiovascular Diseases
Phase 3 Authorised Regeneron Pharmaceuticals Inc Belgium, Czechia, France + 5 more
A Phase 3, Multicenter, Double-Blinded, Randomized Study to Evaluate REGN7508, a Factor XI Monoclonal Antibody, Versus Acetylsalicylic Acid for Prophylaxis of Symptomatic Venous Thromboembolism After Elective Total Knee Arthroplasty (ROXI-ASPEN)
2025-520479-25-00 · CTIS ↗ · Hemic and Lymphatic Diseases
Phase 3 Authorised Regeneron Pharmaceuticals Inc Greece, Italy, Spain
03

Conditions studied with Cenvacibart

6 conditions
Atrial Fibrillation (AF)3Venous Thromboembolism (VTE)2Peripheral Artery Disease (PAD)1Symptomatic Venous Thromboembolism (VTE)1Cancer-Associated Thrombosis (CAT)1End-Stage Kidney Disease (ESKD)1
04

Sponsors

lead sponsor per trial
Lead sponsorTrials
Regeneron Pharmaceuticals9
05

By country register

RegisterTrialsRecruiting
Clinical trials in USA88
Clinical trials in Japan44
Clinical trials in Canada33
Clinical trials in Israel22
Clinical trials in UK11
Clinical trials in Spain11
Clinical trials in Poland11
Clinical trials in Brazil11
Clinical trials in South Korea11
Clinical trials in Belgium11
EU register (CTIS)5—

A trial with sites in more than one country appears in each of those registers. CTIS does not publish a recruiting flag; its trials may also appear in the registers above.

06

Related compounds

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Questions about Cenvacibart trials

How many clinical trials are testing Cenvacibart?

9 current trials in our USA, Japan, Canada, Israel, UK, Spain, Poland, Brazil, South Korea and Belgium registers name Cenvacibart (also registered as REGN7508) as a drug or biological intervention, as of the registry sync on 10 November 2026. Completed and withdrawn studies are not counted.

Are Cenvacibart trials recruiting patients?

Yes. 9 of the 9 trials are recruiting: 8 with sites in USA, 4 with sites in Japan, 3 with sites in Canada, 2 with sites in Israel, 1 with sites in UK, 1 with sites in Spain, 1 with sites in Poland, 1 with sites in Brazil, 1 with sites in South Korea and 1 with sites in Belgium. Eligibility and site contacts are on each trial's record. Only the study team can confirm whether a patient is eligible.

Who sponsors Cenvacibart clinical trials?

The lead sponsor is Regeneron Pharmaceuticals. The number in brackets is how many trials each organisation leads.

Where does this information come from?

Every trial, status, phase and sponsor on this page is copied from public ClinicalTrials.gov records by a daily sync. Nothing here describes how Cenvacibart works or whether it is effective, and it is not medical advice.

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How this page is built

Everything on this page is copied from public ClinicalTrials.gov registry records — it is not written from memory, and nothing here describes how Cenvacibart works or whether it is effective. Each trial links to its own record so you can check it yourself.

This page is built automatically: a daily sync job reads the registry records behind our country trial registers, collects every trial that lists Cenvacibart (or a registered synonym) as a drug or biological intervention, and tabulates the registry fields directly. Placebos and generic comparators are excluded. There is no AI drafting and no per-compound editorial pass, and the page has not been clinically reviewed. The “last verified” date above is the timestamp of that sync, not a review date. Our general editorial approach is described in our editorial standards and corrections policy. The ClinicalTrials.gov data on this page was last retrieved on 10 Nov 2026. How every register is built: methodology · fixes we have made: corrections log.

Please verify before you rely on this. This page is general information for life-science and pharmaceutical professionals. It is not medical advice, and it has not been reviewed by a clinician — our editorial team holds life-science qualifications, not clinical ones. It is not exhaustive and may not reflect the most recent label change. Always check the official prescribing information (US Prescribing Information or EU SmPC) and speak to your doctor or pharmacist before acting on anything here. Drugs in the same class are not automatically interchangeable, and approvals, brand names and indications differ between the US, the EU/Ireland (EMA/HPRA) and other regions. Spotted an error? Tell us — we correct promptly and log it.