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Compound · clinical trials

DOAC clinical trials

Source: ClinicalTrials.gov, U.S. National Library of Medicine — the 6 trials in our Germany, Spain, Italy, France, South Korea, Canada, Belgium, Switzerland, UK, USA, China, Brazil, Japan, Israel, Australia, Netherlands and Poland registers that name DOAC as an intervention. Synced 26 Sep 2026
6Current trials
5Recruiting now
5Lead sponsors
17Country registers
Maintained by Sreepriya Prasannan
MSc Digital Transformation of Life Sciences (Innopharma Education / Griffith College); MSc & BSc Botany HSE Spark Ignite 2026 โ€” Top 14 finalist
Compiled from ClinicalTrials.gov registry records ยท Last verified ยท Editorial standards
At a glance

DOAC is named as an intervention in 6 current clinical trials in our Germany, Spain, Italy, France, South Korea, Canada, Belgium, Switzerland, UK, USA, China, Brazil, Japan, Israel, Australia, Netherlands and Poland registers. 5 are recruiting patients now. The most common phase is Phase 3. The sponsor with the most trials is Insel Gruppe AG, University Hospital Bern (2). The most-studied condition is Carcinoma, Non-small-Cell Lung.

Trials by status

  • Recruiting583%
  • Not yet open117%

Trials by phase

  • Phase 3233%
  • Not applicable233%
  • Phase 2117%
  • Phase 4117%
01

Clinical trials of DOAC

6 trials
StudyPhaseStatusLead sponsorRegisters
Monotherapy With P2Y12 Inhibitors in Patients With Atrial fIbrillation Undergoing Supraflex Stent Implantation
NCT05955365 · ClinicalTrials.gov ↗ · Percutaneous Coronary Intervention (PCI), Atrial Fibrillation (AF), Oral Anticoagulation
Phase 4 Recruiting Insel Gruppe AG, University Hospital Bern Germany, France, Spain, Italy, Netherlands, Belgium, Poland, Switzerland
The Direct Oral Anticoagulation Versus Vitamin K Antagonist After Cardiac Surgery Trial
NCT04284839 · ClinicalTrials.gov ↗ · Bleeding Post Cardiac Surgery, Indication for Anticoagulation
Phase 3 Recruiting Population Health Research Institute Germany, Canada, Australia
A Study of Amivantamab in Participants With Advanced or Metastatic Solid Tumors Including Epidermal Growth Factor Receptor (EGFR)-Mutated Non-Small Cell Lung Cancer
NCT05498428 · Carcinoma, Non-small-Cell Lung
Phase 2 Recruiting Janssen Research & Development, LLC UK, USA, China, Germany, France, Spain, Italy, Brazil, Japan, South Korea, Israel
Early Closure of Left Atrial Appendage for Patients With Atrial Fibrillation and Ischemic Stroke Despite Anticoagulation Therapy
NCT05976685 · ClinicalTrials.gov ↗ · Ischemic Stroke, Atrial Fibrillation
Not applicable Recruiting Insel Gruppe AG, University Hospital Bern Germany, Spain, Belgium, Switzerland
Abbreviated Antithrombotic Therapy After PCI in Patients With AF and AMI
NCT07583784 · ClinicalTrials.gov ↗ · Myocardial Infarction (MI), ST-Segment Elevation Myocardial Infarction(STEMI), NSTEMI - Non-ST-Segment Elevation Myocardial Infarction
Not applicable Recruiting Chonnam National University Hospital South Korea
Hip Fracture Surgery Arterial and Venous Thrombotic Events Prevention
NCT07228663 · ClinicalTrials.gov ↗ · Hip Fracture Surgery, Cardiovascular Prevention, Venous Thromboembolism (VTE)
Phase 3 Not yet open McMaster University Italy, Canada

Registers list studies that are recruiting, about to open, active but closed to enrolment, or enrolling by invitation. The UK and USA registers cover industry-sponsored studies only. Trial titles and statuses are copied from the registry as published.

02

Conditions studied with DOAC

16 conditions
Carcinoma, Non-small-Cell Lung1Bleeding Post Cardiac Surgery1Indication for Anticoagulation1Percutaneous Coronary Intervention (PCI)1Atrial Fibrillation (AF)1Oral Anticoagulation1P2Y12 Inhibitor1Ischemic Stroke1Atrial Fibrillation1Hip Fracture Surgery1Cardiovascular Prevention1Venous Thromboembolism (VTE)1
All 16 conditions
Condition (as registered)Trials
Carcinoma, Non-small-Cell Lung1
Bleeding Post Cardiac Surgery1
Indication for Anticoagulation1
Percutaneous Coronary Intervention (PCI)1
Atrial Fibrillation (AF)1
Oral Anticoagulation1
P2Y12 Inhibitor1
Ischemic Stroke1
Atrial Fibrillation1
Hip Fracture Surgery1
Cardiovascular Prevention1
Venous Thromboembolism (VTE)1
Myocardial Infarction (MI)1
ST-Segment Elevation Myocardial Infarction(STEMI)1
NSTEMI - Non-ST-Segment Elevation Myocardial Infarction1
AF - Atrial Fibrillation1
03

Sponsors

lead sponsor per trial
Lead sponsorTrials
Insel Gruppe AG, University Hospital Bern2
Janssen Research & Development, LLC1
Population Health Research Institute1
McMaster University1
Chonnam National University Hospital1
04

By country register

RegisterTrialsRecruiting
Clinical trials in Germany44
Clinical trials in Spain33
Clinical trials in Italy32
Clinical trials in France22
Clinical trials in South Korea22
Clinical trials in Canada21
Clinical trials in Belgium22
Clinical trials in Switzerland22
Clinical trials in UK11
Clinical trials in USA11
Clinical trials in China11
Clinical trials in Brazil11
Clinical trials in Japan11
Clinical trials in Israel11
Clinical trials in Australia11
Clinical trials in Netherlands11
Clinical trials in Poland11

A trial with sites in more than one country appears in each of those registers.

05

Related compounds

06

Questions about DOAC trials

How many clinical trials are testing DOAC?

6 current trials in our Germany, Spain, Italy, France, South Korea, Canada, Belgium, Switzerland, UK, USA, China, Brazil, Japan, Israel, Australia, Netherlands and Poland registers name DOAC as a drug or biological intervention, as of the registry sync on 26 September 2026. Completed and withdrawn studies are not counted.

Are DOAC trials recruiting patients?

Yes. 5 of the 6 trials are recruiting: 4 with sites in Germany, 3 with sites in Spain, 2 with sites in Italy, 2 with sites in France, 2 with sites in South Korea, 1 with sites in Canada, 2 with sites in Belgium, 2 with sites in Switzerland, 1 with sites in UK, 1 with sites in USA, 1 with sites in China, 1 with sites in Brazil, 1 with sites in Japan, 1 with sites in Israel, 1 with sites in Australia, 1 with sites in Netherlands and 1 with sites in Poland. Eligibility and site contacts are on each trial's record. Only the study team can confirm whether a patient is eligible.

Who sponsors DOAC clinical trials?

Insel Gruppe AG, University Hospital Bern (2), Janssen Research & Development, LLC (1), Population Health Research Institute (1) and McMaster University (1), among 5 lead sponsors in total. The number in brackets is how many trials each organisation leads.

Where does this information come from?

Every trial, status, phase and sponsor on this page is copied from public ClinicalTrials.gov records by a daily sync. Nothing here describes how DOAC works or whether it is effective, and it is not medical advice.

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How this page is built

Everything on this page is copied from public ClinicalTrials.gov registry records โ€” it is not written from memory, and nothing here describes how DOAC works or whether it is effective. Each trial links to its own record so you can check it yourself.

This page is built automatically: a daily sync job reads the registry records behind our country trial registers, collects every trial that lists DOAC (or a registered synonym) as a drug or biological intervention, and tabulates the registry fields directly. Placebos and generic comparators are excluded. There is no AI drafting and no per-compound editorial pass, and the page has not been clinically reviewed. The “last verified” date above is the timestamp of that sync, not a review date. Our general editorial approach is described in our editorial standards and corrections policy. The ClinicalTrials.gov data on this page was last retrieved on 26 Sep 2026.

Please verify before you rely on this. This page is general information for life-science and pharmaceutical professionals. It is not medical advice, and it has not been reviewed by a clinician โ€” our editorial team holds life-science qualifications, not clinical ones. It is not exhaustive and may not reflect the most recent label change. Always check the official prescribing information (US Prescribing Information or EU SmPC) and speak to your doctor or pharmacist before acting on anything here. Drugs in the same class are not automatically interchangeable, and approvals, brand names and indications differ between the US, the EU/Ireland (EMA/HPRA) and other regions. Spotted an error? Tell us โ€” we correct promptly and log it.