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Compound · clinical trials

Daromun clinical trials

Also listed in trial records as L19IL2/L19TNF
Source: ClinicalTrials.gov, U.S. National Library of Medicine — the 5 trials in our USA, Germany, Italy, Spain and Switzerland registers that name Daromun as an intervention. Synced 28 Sep 2026
5Current trials
5Recruiting now
1Lead sponsor
5Country registers
Maintained by Sreepriya Prasannan
MSc Digital Transformation of Life Sciences (Innopharma Education / Griffith College); MSc & BSc Botany HSE Spark Ignite 2026 โ€” Top 14 finalist
Compiled from ClinicalTrials.gov registry records ยท Last verified ยท Editorial standards
At a glance

Daromun is named as an intervention in 5 current clinical trials in our USA, Germany, Italy, Spain and Switzerland registers. 5 are recruiting patients now. The most common phase is Phase 2. The lead sponsor is Philogen S.p.A. The most-studied condition is Locally Advanced Basal Cell Carcinoma.

Trials by status

  • Recruiting5100%

Trials by phase

  • Phase 2480%
  • Phase 3120%
01

Clinical trials of Daromun

5 trials
StudyPhaseStatusLead sponsorRegisters
Efficacy of Daromun Neoadjuvant Intratumoral Treatment in Clinical Stage IIIB/C/D Melanoma Patients
NCT03567889 · ClinicalTrials.gov ↗ · Melanoma Stage IIIB, Melanoma Stage IIIC, Melanoma Stage IIID
Phase 3 Recruiting Philogen S.p.A USA, Spain, Switzerland
Study of the Efficacy of Intratumoral L19IL2 or L19TNF or L19IL2/L19TNF, in Combination With Pembrolizumab, in Unresectable Melanoma Patients
NCT06284590 · Melanoma Stage III, Melanoma Stage IV
Phase 2 Recruiting Philogen S.p.A USA, Germany, Italy
L19IL2 or L19TNF or L19IL2/TNF in Patients With Basal Cell Carcinoma (BCC)
NCT07227350 · ClinicalTrials.gov ↗ · Locally Advanced Basal Cell Carcinoma
Phase 2 Recruiting Philogen S.p.A USA, Germany, Spain, Italy
L19IL2/TNF in Patients With Basal Cell Carcinoma
NCT07227870 · ClinicalTrials.gov ↗ · Locally Advanced Basal Cell Carcinoma
Phase 2 Recruiting Philogen S.p.A USA, Germany, Spain, Italy
L19IL2/L19TNF in Patients With Cutaneous Squamous Cell Carcinoma
NCT07228442 · ClinicalTrials.gov ↗ · Locally Advanced Cutaneous Squamous Cell Carcinoma
Phase 2 Recruiting Philogen S.p.A USA, Germany, Spain, Italy

Registers list studies that are recruiting, about to open, active but closed to enrolment, or enrolling by invitation. The UK and USA registers cover industry-sponsored studies only. Trial titles and statuses are copied from the registry as published.

02

Conditions studied with Daromun

7 conditions
Locally Advanced Basal Cell Carcinoma2Melanoma Stage III1Melanoma Stage IV1Locally Advanced Cutaneous Squamous Cell Carcinoma1Melanoma Stage IIIB1Melanoma Stage IIIC1Melanoma Stage IIID1
03

Sponsors

lead sponsor per trial
Lead sponsorTrials
Philogen S.p.A5
04

By country register

RegisterTrialsRecruiting
Clinical trials in USA55
Clinical trials in Germany44
Clinical trials in Italy44
Clinical trials in Spain44
Clinical trials in Switzerland11

A trial with sites in more than one country appears in each of those registers.

05

Related compounds

06

Questions about Daromun trials

How many clinical trials are testing Daromun?

5 current trials in our USA, Germany, Italy, Spain and Switzerland registers name Daromun (also registered as L19IL2/L19TNF) as a drug or biological intervention, as of the registry sync on 28 September 2026. Completed and withdrawn studies are not counted.

Are Daromun trials recruiting patients?

Yes. 5 of the 5 trials are recruiting: 5 with sites in USA, 4 with sites in Germany, 4 with sites in Italy, 4 with sites in Spain and 1 with sites in Switzerland. Eligibility and site contacts are on each trial's record. Only the study team can confirm whether a patient is eligible.

Who sponsors Daromun clinical trials?

The lead sponsor is Philogen S.p.A. The number in brackets is how many trials each organisation leads.

Where does this information come from?

Every trial, status, phase and sponsor on this page is copied from public ClinicalTrials.gov records by a daily sync. Nothing here describes how Daromun works or whether it is effective, and it is not medical advice.

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How this page is built

Everything on this page is copied from public ClinicalTrials.gov registry records โ€” it is not written from memory, and nothing here describes how Daromun works or whether it is effective. Each trial links to its own record so you can check it yourself.

This page is built automatically: a daily sync job reads the registry records behind our country trial registers, collects every trial that lists Daromun (or a registered synonym) as a drug or biological intervention, and tabulates the registry fields directly. Placebos and generic comparators are excluded. There is no AI drafting and no per-compound editorial pass, and the page has not been clinically reviewed. The “last verified” date above is the timestamp of that sync, not a review date. Our general editorial approach is described in our editorial standards and corrections policy. The ClinicalTrials.gov data on this page was last retrieved on 28 Sep 2026.

Please verify before you rely on this. This page is general information for life-science and pharmaceutical professionals. It is not medical advice, and it has not been reviewed by a clinician โ€” our editorial team holds life-science qualifications, not clinical ones. It is not exhaustive and may not reflect the most recent label change. Always check the official prescribing information (US Prescribing Information or EU SmPC) and speak to your doctor or pharmacist before acting on anything here. Drugs in the same class are not automatically interchangeable, and approvals, brand names and indications differ between the US, the EU/Ireland (EMA/HPRA) and other regions. Spotted an error? Tell us โ€” we correct promptly and log it.