Differential Absorption Kinetics of Grape Seed Extract Polyphenols

Inclusion Criteria: * Men or women, 18-45 years of age * Willing to maintain their usual dietary habits with low (poly)phenol intake and physical activity patterns 3 days before the study visits. Willing and able to comply with all study requirements, including: * Consumption of standardized low-(poly)phenol meals and study treatments. * Completion of all scheduled clinic visits and biological sample collections. * Compliance with dietary restrictions and study instructions. * Able to provide informed consent * Able to comply with and perform the procedures requested by the protocol, specifically eat all the meals and snacks provided by the study; able to come to the clinic up to 5 times during the study * Able to maintain usual physical activity pattern * Able to avoid/abstain from alcohol/and vigorous physical activity for 24 hours prior to and during the study visit Exclusion Criteria: * Men and women with known or suspected intolerance, allergies or hypersensitivity to study foods or interventions * Fasting blood sugar \>125 mg/dL * Men and women with blood pressure \>160 mmHg (systolic) / 100 mmHg (diastolic) at the screening visit * Men and women with history of diabetes cardiovascular events, respiratory, renal, gastrointestinal, hepatic or eye disease or surgery- within a year * Men and women who have or had cancer other than non-melanoma skin cancer in the past 5 years * Men and women taking over the counter or prescription medications or dietary supplements that may interfere with study procedures or endpoints * Men and women who are on a specialized diet (vegan, vegetarian, keto, etc.) * Men and women who are not weight stable (+/-10lbs in previous 2 months) * Men and women who have excessive use of drugs or alcohol (i.e.., addictions) within the past 2 years * Men and women with documented physical or mental disease/condition, which might limit participation in or completion of the study or, that, in the opinion of the investigator, could interfere with the interpretation of the study results. * Women who are known to be pregnant or who are intending to become pregnant over the course of the study * Women who are lactating * Major trauma or a surgical event within 2 months (or longer depending on trauma or event) and after consultation with PI. * Has used antibiotics within the previous 2 months * History of an eating disorder (e.g., anorexia nervosa, bulimia nervosa, or binge eating) diagnosed by a health professional * Excessive coffee and tea consumers (\> 4 cups/d) * Donated blood within the last 3 months * Women who are taking an unstable dose and brand of hormonal contraceptives and/or a stable dose and brand for less than 6 months * Unusual working hours i.e., working overnight (e.g., 3rd shift) * Participant who is a current smoker and unable to be smoke-free for 24 h.