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Clinical Trials in the USA / NCT07625046
Active, not recruiting Not applicable

How Fig Polyphenols Affect Blood Sugar and Insulin Levels After Eating in Adults at Risk for Diabetes

NCT07625046 · tracked via the Priya Life Science USA tracker
Sponsor
Clinical Nutrition Research Center, Illinois Institute of Technology
Phase
Not applicable
Started
2026-03-12
Last updated
2026-08-31

Condition(s) studied

Pre Diabetic

Investigational drug(s) / intervention(s)

FigControl

Fig: 40g of fig

Control: Calorie matched control breakfast

Study summary

The study purpose is to understand how the body absorbs and metabolizes nutrient-like components in dried figs called polyphenols over 24 hours. The study is also done to know if polyphenols will help a hormone called insulin work better in the body, so to look further into the possibility of figs being a functional food for the pre-diabetic population.

Eligibility

Sex
FEMALE
Min age
30 Years
Max age
50 Years
Healthy volunteers
No
Inclusion Criteria: * Be between 30-50 years old. * Have a BMI of 25-35 kg/m². * Have fasting blood glucose between 100-125 mg/dL or Glycated hemoglobin (HbA1c) between 5.7-6.4%. * Be non-smokers for at least 12 months. * Be generally healthy, with no major organ-related diseases. * Not take medications or supplements that could interfere with the study. * Be able to follow study procedures, including dietary restrictions and scheduled visits Exclusion Criteria: * Smoker * Vegetarian * Taking over the counter supplements (e.g. fiber supplements, probiotics and/or prebiotics, antioxidants, anti-inflammation) and/or taking prescription medications that may interfere with study procedures or endpoints (e.g. Gastrointestinal medications, antibiotics) within the last 30 days * Have cancer other than non-melanoma skin cancer in previous 5 years * Taking unstable dose of hormonal contraceptive and/or stable dose less than 6 months * Planning to become pregnant * Pregnant and/or breast-feeding * Excessive exercisers or trained athletes * Excessive coffee/tea drinker * Donated blood within last 3 months * Have allergies/intolerances to foods consumed in the study * Regular consumption of dried fruits exceeds \> 2 servings per day * Actively losing weight/ trying to lose weight (unstable body weight fluctuations of \> 5 lbs in 3 months) * Addicted to drugs or alcohol or have significant psychiatric or neurological disturbances * Past smokers may be allowed in the study if stopped \>2 years

Primary outcome measure(s)

  • Blood glucose levels — From enrollment to the end of treatment at 2 weeks
    Blood glucose levels with and without dried figs.
  • Blood Insulin levels — From enrollment to the end of treatment at 2 weeks
    Blood insulin levels with and without dried figs.

Trial sites (1)

FacilityCityRegionStatus
Illinois Tech Chicago Illinois

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Official registry record

This page summarises publicly available registry data for informational purposes — not medical advice. Eligibility is determined by each study team; patients should discuss participation with their clinician.

View NCT07625046 on ClinicalTrials.gov ↗ ← All trials in the USA