VX-581 clinical trials
VX-581 is named as an intervention in 2 current clinical trials in our USA register. 2 are recruiting patients now. All registered phases are Phase 1. The lead sponsor is Vertex Pharmaceuticals Incorporated. The most-studied condition is Cystic Fibrosis.
Patient leaflets for VX-581
The package leaflet is the official guide for patients that comes with every medicine. These links go to the regulators that publish it.
- UKUnited Kingdom: Search MHRA ProductsPatient information leaflets and SmPCs for UK-licensed products.
- USUnited States: Search DailyMedFDA-approved labels, including patient and medication guides.
Leaflets differ between brands and countries; always read the one that comes with your own medicine. This is regulatory information, not medical advice.
Trials by status
Trials by phase
Clinical trials of VX-581
2 trials| Study | Phase | Status | Lead sponsor | Registers |
|---|---|---|---|---|
|
Evaluation of VX-581 in Healthy Participants and in Participants With Cystic Fibrosis
NCT07283770 · Cystic Fibrosis
|
Phase 1 | Recruiting | Vertex Pharmaceuticals Incorporated | USA |
|
A Phase 1 Relative Bioavailability Study of a VX-581 Tablet Formulation
NCT07813039 · ClinicalTrials.gov ↗ · Cystic Fibrosis
|
Phase 1 | Recruiting | Vertex Pharmaceuticals Incorporated | USA |
Registers list studies that are recruiting, about to open, active but closed to enrolment, or enrolling by invitation. The UK and USA registers cover industry-sponsored studies only. Trial titles and statuses are copied from the registry as published.
Conditions studied with VX-581
1 conditionSponsors
lead sponsor per trial| Lead sponsor | Trials |
|---|---|
| Vertex Pharmaceuticals Incorporated | 2 |
By country register
| Register | Trials | Recruiting |
|---|---|---|
| Clinical trials in USA | 2 | 2 |
A trial with sites in more than one country appears in each of those registers.
Related compounds
Questions about VX-581 trials
How many clinical trials are testing VX-581?
2 current trials in our USA register name VX-581 as a drug or biological intervention, as of the registry sync on 20 October 2026. Completed and withdrawn studies are not counted.
Are VX-581 trials recruiting patients?
Yes. 2 of the 2 trials are recruiting: 2 with sites in USA. Eligibility and site contacts are on each trial's record. Only the study team can confirm whether a patient is eligible.
Who sponsors VX-581 clinical trials?
The lead sponsor is Vertex Pharmaceuticals Incorporated. The number in brackets is how many trials each organisation leads.
Where does this information come from?
Every trial, status, phase and sponsor on this page is copied from public ClinicalTrials.gov records by a daily sync. Nothing here describes how VX-581 works or whether it is effective, and it is not medical advice.
How this page is built
Everything on this page is copied from public ClinicalTrials.gov registry records — it is not written from memory, and nothing here describes how VX-581 works or whether it is effective. Each trial links to its own record so you can check it yourself.
- ClinicalTrials.gov (U.S. National Library of Medicine) ↗ Trial IDs, titles, intervention names and synonyms, phase, overall status, lead sponsor and conditions for every trial on this page
This page is built automatically: a daily sync job reads the registry records behind our country trial registers, collects every trial that lists VX-581 (or a registered synonym) as a drug or biological intervention, and tabulates the registry fields directly. Placebos and generic comparators are excluded. There is no AI drafting and no per-compound editorial pass, and the page has not been clinically reviewed. The “last verified” date above is the timestamp of that sync, not a review date. Our general editorial approach is described in our editorial standards and corrections policy. The ClinicalTrials.gov data on this page was last retrieved on 20 Oct 2026. How every register is built: methodology · fixes we have made: corrections log.