Clinical Trials in the USA / NCT07887425
Recruiting
Not applicable
Corneal Trauma Diagnostic Study
NCT07887425 · tracked via the Priya Life Science USA tracker
Condition(s) studied
Ocular Trauma
Investigational drug(s) / intervention(s)
Tear fluid collection with mass spec analysis.
Tear fluid collection with mass spec analysis.: Tear fluid collection with mass spec analysis.
Study summary
Tear fluid will be collected from patients diagnosed with ocular trauma at the University of Pittsburgh Medical Center to evaluate biomarkers.
Eligibility
Inclusion Criteria:
* Minimum age of 18 years.
* Diagnosis of visually significant cataract and scheduled for routine cataract surgery at UPMC with a clear corneal incision or
* scheduled for clinical repair of a full-thickness corneal laceration.
Exclusion Criteria:
* Prior history of full-thickness corneal laceration from trauma or from a surgical procedure
* Current diagnosis of glaucoma or use of ocular hypotensive drops or oral aqueous suppressants.
* Actively being treated for the diagnosis of dry eyes with a topical drop other than artificial tears.
* Actively taking oral or topical supplementation of Vitamin C.
* Scheduled for additional eye surgeries, combined with the routine cataract surgery.
* Surgical plan that would include incisions in the clear for cataract extraction.
* Inability to provide informed consent due to suspected head trauma, altered mental status, or other factors impairing decision-making capacity.
Primary outcome measure(s)
- Primary Outcome - Ascorbic Acid — One year.
Measurement of ascorbic acid using mass spec
Trial sites (1)
| Facility | City | Region | Status |
|---|---|---|---|
| UPMC Vision Insititute - Mercy Pavilion | Pittsburgh | Pennsylvania | Recruiting |
Official registry record
This page summarises publicly available registry data for informational purposes — not medical advice. Eligibility is determined by each study team; patients should discuss participation with their clinician.
View NCT07887425 on ClinicalTrials.gov ↗ ← All trials in the USA