Bomedemstat clinical trials
Bomedemstat is named as an intervention in 4 current clinical trials in our USA, UK, Italy, Canada, Australia, Israel, China, Germany, France, Spain, Sweden, Poland, Turkey, Japan, Taiwan, Netherlands, Belgium, Portugal, South Korea, Denmark, Austria and Mexico registers. 2 are recruiting patients now. The most common phase is Phase 3. The lead sponsor is Merck Sharp & Dohme LLC. The most-studied condition is Essential Thrombocythemia.
How Bomedemstat works
All drug targets →- Lysine-specific histone demethylase 1 inhibitor InhibitorTarget: KDM1A lysine demethylase 1AChEMBL only
- Essential thrombocythemiaPhase 3
- Acquired polycythemia veraPhase 2
- Acute myeloid leukemia by FAB classificationPhase 2
- Myelodysplastic syndromePhase 2
- MyelofibrosisPhase 2
- Myeloproliferative disorderPhase 2
- Acute myeloid leukemiaPhase 1/2
- Small cell lung carcinomaPhase 1/2
Mechanisms and diseases from ChEMBL via the Open Targets Platform (release 26.09), ChEMBL record CHEMBL4297289, CC BY-SA 3.0. The Guide to Pharmacology has no record of this medicine, so its targets rest on ChEMBL alone. Trial phases are not approvals: approved uses are shown from the regulators' own records where we hold them.
Patient leaflets for Bomedemstat
The package leaflet is the official guide for patients that comes with every medicine. These links go to the regulators that publish it.
- UKUnited Kingdom: Search MHRA ProductsPatient information leaflets and SmPCs for UK-licensed products.
- USUnited States: Search DailyMedFDA-approved labels, including patient and medication guides.
Leaflets differ between brands and countries; always read the one that comes with your own medicine. This is regulatory information, not medical advice.
Reference identifiers for Bomedemstat
- ChEMBL
- CHEMBL4297289
- DrugBank
- DB17234
- PubChem CID
- 122460381
- CAS number
- 1990504-34-1
- FDA UNII
- Y2T4ALDEAT
- Wikidata
- Q118727468
- Wikipedia
- Bomedemstat
Codes that identify this medicine in other databases, from Wikidata (CC0), matched by its ChEMBL ID. The ATC code is the WHO classification of what the medicine is used for.
Trials by status
Trials by phase
Clinical trials of Bomedemstat
4 trialsRegisters list studies that are recruiting, about to open, active but closed to enrolment, or enrolling by invitation. The UK and USA registers cover industry-sponsored studies only. Trial titles and statuses are copied from the registry as published.
Conditions studied with Bomedemstat
6 conditionsSponsors
lead sponsor per trial| Lead sponsor | Trials |
|---|---|
| Merck Sharp & Dohme LLC | 4 |
By country register
A trial with sites in more than one country appears in each of those registers.
Related compounds
Questions about Bomedemstat trials
How many clinical trials are testing Bomedemstat?
4 current trials in our USA, UK, Italy, Canada, Australia, Israel, China, Germany, France, Spain, Sweden, Poland, Turkey, Japan, Taiwan, Netherlands, Belgium, Portugal, South Korea, Denmark, Austria and Mexico registers name Bomedemstat (also registered as MK-3543) as a drug or biological intervention, as of the registry sync on 9 November 2026. Completed and withdrawn studies are not counted.
Are Bomedemstat trials recruiting patients?
Yes. 2 of the 4 trials are recruiting: 2 with sites in USA, 1 with sites in UK, 1 with sites in Italy, 1 with sites in Canada, 1 with sites in Australia and 1 with sites in Israel. Eligibility and site contacts are on each trial's record. Only the study team can confirm whether a patient is eligible.
Who sponsors Bomedemstat clinical trials?
The lead sponsor is Merck Sharp & Dohme LLC. The number in brackets is how many trials each organisation leads.
Where does this information come from?
Every trial, status, phase and sponsor on this page is copied from public ClinicalTrials.gov records by a daily sync. Nothing here describes how Bomedemstat works or whether it is effective, and it is not medical advice.
How this page is built
Everything on this page is copied from public ClinicalTrials.gov registry records — it is not written from memory, and nothing here describes how Bomedemstat works or whether it is effective. Each trial links to its own record so you can check it yourself.
- ClinicalTrials.gov (U.S. National Library of Medicine) ↗ Trial IDs, titles, intervention names and synonyms, phase, overall status, lead sponsor and conditions for every trial on this page
This page is built automatically: a daily sync job reads the registry records behind our country trial registers, collects every trial that lists Bomedemstat (or a registered synonym) as a drug or biological intervention, and tabulates the registry fields directly. Placebos and generic comparators are excluded. There is no AI drafting and no per-compound editorial pass, and the page has not been clinically reviewed. The “last verified” date above is the timestamp of that sync, not a review date. Our general editorial approach is described in our editorial standards and corrections policy. The ClinicalTrials.gov data on this page was last retrieved on 9 Nov 2026. How every register is built: methodology · fixes we have made: corrections log.