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Priya Life Science Compound trial record
Compound · clinical trials

Vepugratinib clinical trials

Also listed in trial records as LY3866288, LOXO-435
Source: ClinicalTrials.gov, U.S. National Library of Medicine — the 3 trials in our USA, UK, China, Germany, France, Spain, Italy, Netherlands, Canada, Japan, South Korea, Australia, Denmark, Poland, Czechia, Turkey, Brazil, Taiwan, Norway and Israel registers that name Vepugratinib as an intervention. Synced 9 Nov 2026
3Current trials
2Recruiting now
1Lead sponsor
20Country registers
At a glance

Vepugratinib is named as an intervention in 3 current clinical trials in our USA, UK, China, Germany, France, Spain, Italy, Netherlands, Canada, Japan, South Korea, Australia, Denmark, Poland, Czechia, Turkey, Brazil, Taiwan, Norway and Israel registers. 2 are recruiting patients now. The most common phase is Phase 3. The lead sponsor is Eli Lilly and Company. The most-studied condition is Urinary Bladder Neoplasms.

Patient leaflets for Vepugratinib

The package leaflet is the official guide for patients that comes with every medicine. These links go to the regulators that publish it.

  • UK
    United Kingdom: Search MHRA Products
    Patient information leaflets and SmPCs for UK-licensed products.
  • US
    United States: Search DailyMed
    FDA-approved labels, including patient and medication guides.

Leaflets differ between brands and countries; always read the one that comes with your own medicine. This is regulatory information, not medical advice.

Trials by status

  • Recruiting267%
  • Not yet open133%

Trials by phase

  • Phase 3133%
  • Phase 1133%
  • Phase 2133%
01

Clinical trials of Vepugratinib

3 trials
StudyPhaseStatusLead sponsorRegisters
A Study of Vepugratinib (LY3866288) in Participants With Cancer in the Urinary Tract
NCT07218380 · Carcinoma, Transitional Cell, Urinary Bladder Neoplasms, Neoplasm Metastasis
Phase 3 Recruiting Eli Lilly and Company UK, USA, China, Germany, France, Spain, Italy, Netherlands, Denmark, Poland, Czechia, Turkey, Canada, Brazil, Japan, South Korea, Taiwan, Australia
FORAGER-1: A Study of Vepugratinib (LY3866288; LOXO-435) in Participants With Cancer With a Change in a Gene Called FGFR3
NCT05614739 · Urinary Bladder Neoplasms, Neoplasm Metastasis, Ureteral Neoplasms
Phase 1 Recruiting Eli Lilly and Company UK, USA, China, Germany, France, Spain, Italy, Netherlands, Norway, Canada, Japan, South Korea, Australia, Israel
A Study of Vepugratinib (LY3866288) in Adults With Non-Muscle Invasive Bladder Cancer and Upper Tract Urothelial Cancer
NCT07827612 · Urinary Bladder Neoplasms, Urologic Neoplasms, Receptor, Fibroblast Growth Factor, Type 3
Phase 2 Not yet open Eli Lilly and Company USA

Registers list studies that are recruiting, about to open, active but closed to enrolment, or enrolling by invitation. The UK and USA registers cover industry-sponsored studies only. Trial titles and statuses are copied from the registry as published.

02

Conditions studied with Vepugratinib

6 conditions
Urinary Bladder Neoplasms3Neoplasm Metastasis2Carcinoma, Transitional Cell1Ureteral Neoplasms1Urologic Neoplasms1Receptor, Fibroblast Growth Factor, Type 31
05

Related compounds

06

Questions about Vepugratinib trials

How many clinical trials are testing Vepugratinib?

3 current trials in our USA, UK, China, Germany, France, Spain, Italy, Netherlands, Canada, Japan, South Korea, Australia, Denmark, Poland, Czechia, Turkey, Brazil, Taiwan, Norway and Israel registers name Vepugratinib (also registered as LY3866288) as a drug or biological intervention, as of the registry sync on 9 November 2026. Completed and withdrawn studies are not counted.

Are Vepugratinib trials recruiting patients?

Yes. 2 of the 3 trials are recruiting: 2 with sites in USA, 2 with sites in UK, 2 with sites in China, 2 with sites in Germany, 2 with sites in France, 2 with sites in Spain, 2 with sites in Italy, 2 with sites in Netherlands, 2 with sites in Canada, 2 with sites in Japan, 2 with sites in South Korea, 2 with sites in Australia, 1 with sites in Denmark, 1 with sites in Poland, 1 with sites in Czechia, 1 with sites in Turkey, 1 with sites in Brazil, 1 with sites in Taiwan, 1 with sites in Norway and 1 with sites in Israel. Eligibility and site contacts are on each trial's record. Only the study team can confirm whether a patient is eligible.

Who sponsors Vepugratinib clinical trials?

The lead sponsor is Eli Lilly and Company. The number in brackets is how many trials each organisation leads.

Where does this information come from?

Every trial, status, phase and sponsor on this page is copied from public ClinicalTrials.gov records by a daily sync. Nothing here describes how Vepugratinib works or whether it is effective, and it is not medical advice.

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How this page is built

Everything on this page is copied from public ClinicalTrials.gov registry records — it is not written from memory, and nothing here describes how Vepugratinib works or whether it is effective. Each trial links to its own record so you can check it yourself.

This page is built automatically: a daily sync job reads the registry records behind our country trial registers, collects every trial that lists Vepugratinib (or a registered synonym) as a drug or biological intervention, and tabulates the registry fields directly. Placebos and generic comparators are excluded. There is no AI drafting and no per-compound editorial pass, and the page has not been clinically reviewed. The “last verified” date above is the timestamp of that sync, not a review date. Our general editorial approach is described in our editorial standards and corrections policy. The ClinicalTrials.gov data on this page was last retrieved on 9 Nov 2026. How every register is built: methodology · fixes we have made: corrections log.

Please verify before you rely on this. This page is general information for life-science and pharmaceutical professionals. It is not medical advice, and it has not been reviewed by a clinician — our editorial team holds life-science qualifications, not clinical ones. It is not exhaustive and may not reflect the most recent label change. Always check the official prescribing information (US Prescribing Information or EU SmPC) and speak to your doctor or pharmacist before acting on anything here. Drugs in the same class are not automatically interchangeable, and approvals, brand names and indications differ between the US, the EU/Ireland (EMA/HPRA) and other regions. Spotted an error? Tell us — we correct promptly and log it.