Amoxicillin clinical trials
Amoxicillin is named as an intervention in 29 current clinical trials in our China, Canada, France, Switzerland, Mexico, Brazil, Egypt, Japan, Germany, Spain, Italy, Netherlands, Denmark, South Korea and Taiwan registers. 20 are recruiting patients now. The most common phase is Phase 4. The sponsor with the most trials is First People's Hospital of Hangzhou (2). The most-studied condition is HELICOBACTER PYLORI INFECTIONS. The EU clinical trials register (CTIS) separately lists 7 authorised or ongoing trials.
Where Amoxicillin is approved
All regulators →Of the three regulators tracked here, the first to approve Amoxicillin was the US, on 18 Jan 1974. It is approved in 2 of the 3 regulators tracked here.
From the regulators' own registers: FDA Drugs@FDA, the EMA medicines list and Health Canada's Notice of Compliance database. Dates are the first listed approval of a product containing only this substance; combination products and nationally authorised EU medicines are not counted.
What health systems spend on Amoxicillin
All medicines →From NHSBSA Prescription Cost Analysis (Open Government Licence v3.0) and CMS State Drug Utilization Data. Both are gross amounts: neither system publishes its discounts or rebates per drug. Products combining several substances are not counted here.
How Amoxicillin works
All drug targets →- Bacterial penicillin-binding protein inhibitor InhibitorChEMBL only
- Acute otitis mediaPhase 3
- COVID-19Phase 3
- FeverPhase 3
- Helicobacter pylori infectious diseasePhase 3
- Intraventricular hemorrhagePhase 3
- Low back painPhase 3
- Parkinson diseasePhase 3
- SepsisPhase 3
- TachypneaPhase 3
- WheezingPhase 3
Mechanisms and diseases from ChEMBL via the Open Targets Platform (release 26.09), ChEMBL record CHEMBL1082, CC BY-SA 3.0. Targets checked against the IUPHAR/BPS Guide to PHARMACOLOGY (2026.3.1), ligand 10895, CC BY-SA 4.0. Trial phases are not approvals: approved uses are shown from the regulators' own records where we hold them.
Patient leaflets for Amoxicillin
The package leaflet is the official guide for patients that comes with every medicine. These links go to the regulators that publish it.
- IEIreland: 13 products on the HPRA listEach product record links to the HPRA, which publishes the leaflet and SmPC.
- UKUnited Kingdom: Search MHRA ProductsPatient information leaflets and SmPCs for UK-licensed products.
- USUnited States: Search DailyMedFDA-approved labels, including patient and medication guides.
Leaflets differ between brands and countries; always read the one that comes with your own medicine. This is regulatory information, not medical advice.
Reference identifiers for Amoxicillin
- ATC code
- J01CA04
- ChEMBL
- CHEMBL1082
- DrugBank
- DB01060
- PubChem CID
- 40467057
- CAS number
- 26787-78-0
- FDA UNII
- 9EM05410Q9
- Wikidata
- Q201928
- Wikipedia
- Amoxicillin
Codes that identify this medicine in other databases, from Wikidata (CC0), matched by its ChEMBL ID. The ATC code is the WHO classification of what the medicine is used for.
Trials by status
Trials by phase
Clinical trials of Amoxicillin
29 trialsRegisters list studies that are recruiting, about to open, active but closed to enrolment, or enrolling by invitation. The UK and USA registers cover industry-sponsored studies only. Trial titles and statuses are copied from the registry as published.
Amoxicillin in the EU trials register (CTIS)
7 trialsAuthorised or ongoing trials in the EU Clinical Trials Information System that list a product containing Amoxicillin. Many trials are registered in both CTIS and ClinicalTrials.gov, so these are shown separately rather than added to the count above. Trials with a site in Ireland are listed first.
Amoxicillin across our data
Ireland · EU · USThe same active substance in our other registers, matched by its exact name. Each entry links to the register record it comes from.
Licensed in Ireland (HPRA)
13 single-substance products containing Amoxicillin on the HPRA medicines list.
- Amoxicillin 250 mg hard capsulesClonmel Healthcare Ltd · PA0126/282/001 · Marketed
- Amoxicillin 250 mg/5 ml powder for oral suspensionClonmel Healthcare Ltd · PA0126/282/004 · Marketed
- Amoxicillin 500 mg hard capsulesClonmel Healthcare Ltd · PA0126/282/002 · Marketed
- Amoxicillin Delbert 500 mg powder for solution for injection or infusionLaboratoires DELBERT · PA23217/001/001 · Marketed
- Oramox 125 mg/5 ml powder for oral suspensionAthlone Pharmaceuticals Limited · PA1418/013/001 · Marketed
Supply shortages
- Amoxicillin and amoxicillin/clavulanic acidEU (EMA) · Shortage resolved · first published 27 Jan 2023
- Amoxicillin AL TSGermany (BfArM) · Other reason · 1 May 2024 to 1 Dec 2026
- Amoxicillin AL TSGermany (BfArM) · Other reason · 1 May 2024 to 1 Dec 2026
- Amoxicillin AL TSGermany (BfArM) · Other reason · 1 May 2024 to 1 Dec 2026
Conditions studied with Amoxicillin
36 conditionsAll 36 conditions
| Condition (as registered) | Trials |
|---|---|
| HELICOBACTER PYLORI INFECTIONS | 6 |
| Helicobacter Pylori Infection | 3 |
| Antibiotic Prophylaxis | 3 |
| Helicobacter Infection | 2 |
| Community-acquired Pneumonia | 2 |
| Acute Coronary Syndrome | 1 |
| Helicobacter Pylori | 1 |
| Gastritis, Indigestion, Helicobacter Pylori Infection, Gastric Cancer, Peptic Ulcer | 1 |
| Helicobacter Pylori Eradication Rate | 1 |
| Helicobacter Pylori Infection Chronic Gastrit | 1 |
| Chronic Subdural Hematomas | 1 |
| Infections Joint Prosthetic | 1 |
| Endocarditis Infective | 1 |
| Antibiotic Side Effect | 1 |
| MSK Conditions | 1 |
| Chronic Low Back Pain (CLBP) | 1 |
| Modic Changes | 1 |
| Cystectomy | 1 |
| Bladder Cancer Requiring Cystectomy | 1 |
| Postoperative Infections | 1 |
| Metastatic Castration-Resistant Prostate Cancer (mCRPC) | 1 |
| Allergy Amoxicillin | 1 |
| Beta-lactam Allergy Labels | 1 |
| Lactating Women on Select DOI | 1 |
| Breastfed Infants of Mothers on Select DOI | 1 |
| Autoimmune Rheumatic Diseases | 1 |
| Tooth Extraction | 1 |
| Infection Prevention | 1 |
| Alveolar Ridge Augmentation | 1 |
| Bone Grafting | 1 |
| Syphilis, Congenital | 1 |
| Helicobacter Pylori Gastrointestinal Tract Infection | 1 |
| Helicobacter Pylori Infected Patients | 1 |
| Myeloma | 1 |
| Lymphoma | 1 |
| Leukemia | 1 |
Sponsors
lead sponsor per trial+ 12 more sponsors in the trial list above.
By country register
A trial with sites in more than one country appears in each of those registers. CTIS does not publish a recruiting flag; its trials may also appear in the registers above.
Related compounds
Questions about Amoxicillin trials
How many clinical trials are testing Amoxicillin?
29 current trials in our China, Canada, France, Switzerland, Mexico, Brazil, Egypt, Japan, Germany, Spain, Italy, Netherlands, Denmark, South Korea and Taiwan registers name Amoxicillin as a drug or biological intervention, as of the registry sync on 10 November 2026. Completed and withdrawn studies are not counted.
Are Amoxicillin trials recruiting patients?
Yes. 20 of the 29 trials are recruiting: 7 with sites in China, 2 with sites in Canada, 2 with sites in France, 2 with sites in Switzerland, 1 with sites in Mexico, 1 with sites in Brazil, 2 with sites in Egypt, 1 with sites in Japan, 1 with sites in Germany, 1 with sites in Spain, 1 with sites in Denmark and 1 with sites in Taiwan. Eligibility and site contacts are on each trial's record. Only the study team can confirm whether a patient is eligible.
Who sponsors Amoxicillin clinical trials?
First People's Hospital of Hangzhou (2), Tanta University (2), Qilu Hospital of Shandong University (1) and Second Affiliated Hospital, Zhejiang University, School of Medicine (1), among 27 lead sponsors in total. The number in brackets is how many trials each organisation leads.
Is Amoxicillin licensed in Ireland?
Yes. The HPRA medicines list includes 13 single-substance products containing Amoxicillin, for example Amoxicillin 250 mg hard capsules (Clonmel Healthcare Ltd). A licence does not mean a product is currently marketed or reimbursed; see each product's record.
Is there a Amoxicillin shortage?
The registers we track list 4 entries for Amoxicillin: Amoxicillin and amoxicillin/clavulanic acid (EU: shortage resolved); 3 German notices. Shortages are product- and country-specific; check with a pharmacist.
Where does this information come from?
Every trial, status, phase and sponsor on this page is copied from public ClinicalTrials.gov records by a daily sync. Nothing here describes how Amoxicillin works or whether it is effective, and it is not medical advice.
How this page is built
Everything on this page is copied from public ClinicalTrials.gov registry records — it is not written from memory, and nothing here describes how Amoxicillin works or whether it is effective. Each trial links to its own record so you can check it yourself.
- ClinicalTrials.gov (U.S. National Library of Medicine) ↗ Trial IDs, titles, intervention names and synonyms, phase, overall status, lead sponsor and conditions for every trial on this page
This page is built automatically: a daily sync job reads the registry records behind our country trial registers, collects every trial that lists Amoxicillin (or a registered synonym) as a drug or biological intervention, and tabulates the registry fields directly. Placebos and generic comparators are excluded. There is no AI drafting and no per-compound editorial pass, and the page has not been clinically reviewed. The “last verified” date above is the timestamp of that sync, not a review date. Our general editorial approach is described in our editorial standards and corrections policy. The ClinicalTrials.gov data on this page was last retrieved on 10 Nov 2026. How every register is built: methodology · fixes we have made: corrections log.