Ireland
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Priya Life Science Compound trial record
Compound · clinical trials

Efruxifermin clinical trials

Source: ClinicalTrials.gov, U.S. National Library of Medicine — the 3 trials in our UK, USA, India, Switzerland, Turkey, Canada, Mexico, South Korea, Australia, Israel, Germany, France, Spain, Italy, Poland, Taiwan, Denmark, Brazil and Japan registers that name Efruxifermin as an intervention. Synced 10 Nov 2026
3Current trials
2Recruiting now
1Lead sponsor
19Country registers
At a glance

Efruxifermin is named as an intervention in 3 current clinical trials in our UK, USA, India, Switzerland, Turkey, Canada, Mexico, South Korea, Australia, Israel, Germany, France, Spain, Italy, Poland, Taiwan, Denmark, Brazil and Japan registers. 2 are recruiting patients now. All registered phases are Phase 3. The lead sponsor is Akero Therapeutics, Inc. The most-studied condition is NASH With Fibrosis.

How Efruxifermin works

All drug targets →
Diseases it has been tested for in clinical trials, by furthest phase
  • Cirrhosis of liverPhase 3
  • FibrosisPhase 3
  • Metabolic dysfunction-associated steatohepatitisPhase 3
  • Non-alcoholic fatty liverPhase 3
  • Type 2 diabetes mellitusPhase 1

Mechanisms and diseases from ChEMBL via the Open Targets Platform (release 26.09), ChEMBL record CHEMBL4594389, CC BY-SA 3.0. The Guide to Pharmacology has no record of this medicine, so its targets rest on ChEMBL alone. Trial phases are not approvals: approved uses are shown from the regulators' own records where we hold them.

Patient leaflets for Efruxifermin

The package leaflet is the official guide for patients that comes with every medicine. These links go to the regulators that publish it.

  • UK
    United Kingdom: Search MHRA Products
    Patient information leaflets and SmPCs for UK-licensed products.
  • US
    United States: Search DailyMed
    FDA-approved labels, including patient and medication guides.

Leaflets differ between brands and countries; always read the one that comes with your own medicine. This is regulatory information, not medical advice.

Trials by status

  • Recruiting267%
  • Active, closed133%

Trials by phase

  • Phase 33100%
01

Clinical trials of Efruxifermin

3 trials
StudyPhaseStatusLead sponsorRegisters
A Study Evaluating Efruxifermin in Subjects With Non-Cirrhotic Nonalcoholic Steatohepatitis (NASH)/Metabolic Dysfunction-Associated Steatohepatitis (MASH) and Fibrosis
NCT06215716 · NASH With Fibrosis, MASH With Fibrosis
Phase 3 Recruiting Akero Therapeutics, Inc UK, USA, India, Germany, France, Spain, Italy, Poland, Switzerland, Turkey, Canada, Mexico, South Korea, Taiwan, Australia, Israel
A Study Evaluating Efruxifermin in Subjects With Compensated Cirrhosis Due to NASH/MASH
NCT06528314 · NASH - Nonalcoholic Steatohepatitis, MASH - Metabolic Dysfunction-Associated Steatohepatitis
Phase 3 Recruiting Akero Therapeutics, Inc UK, USA, India, Germany, France, Spain, Italy, Denmark, Poland, Switzerland, Turkey, Canada, Brazil, Mexico, Japan, South Korea, Australia, Israel
A Study Evaluating Efruxifermin in Subjects With Non-invasively Diagnosed Nonalcoholic Steatohepatitis (NASH)/Metabolic Dysfunction-Associated Steatohepatitis (MASH) and Nonalcoholic Fatty Liver Disease (NAFLD)/Metabolic Dysfunction-Associated Steatotic Liver Disease (MASLD)
NCT06161571 · NASH/MASH, NAFLD/MASLD
Phase 3 Active, closed Akero Therapeutics, Inc UK, USA, India, Switzerland, Turkey, Canada, Mexico, South Korea, Taiwan, Australia, Israel

Registers list studies that are recruiting, about to open, active but closed to enrolment, or enrolling by invitation. The UK and USA registers cover industry-sponsored studies only. Trial titles and statuses are copied from the registry as published.

02

Conditions studied with Efruxifermin

6 conditions
NASH With Fibrosis1MASH With Fibrosis1NASH - Nonalcoholic Steatohepatitis1MASH - Metabolic Dysfunction-Associated Steatohepatitis1NASH/MASH1NAFLD/MASLD1
05

Questions about Efruxifermin trials

How many clinical trials are testing Efruxifermin?

3 current trials in our UK, USA, India, Switzerland, Turkey, Canada, Mexico, South Korea, Australia, Israel, Germany, France, Spain, Italy, Poland, Taiwan, Denmark, Brazil and Japan registers name Efruxifermin as a drug or biological intervention, as of the registry sync on 10 November 2026. Completed and withdrawn studies are not counted.

Are Efruxifermin trials recruiting patients?

Yes. 2 of the 3 trials are recruiting: 2 with sites in UK, 2 with sites in USA, 2 with sites in India, 2 with sites in Switzerland, 2 with sites in Turkey, 2 with sites in Canada, 2 with sites in Mexico, 2 with sites in South Korea, 2 with sites in Australia, 2 with sites in Israel, 2 with sites in Germany, 2 with sites in France, 2 with sites in Spain, 2 with sites in Italy, 2 with sites in Poland, 1 with sites in Taiwan, 1 with sites in Denmark, 1 with sites in Brazil and 1 with sites in Japan. Eligibility and site contacts are on each trial's record. Only the study team can confirm whether a patient is eligible.

Who sponsors Efruxifermin clinical trials?

The lead sponsor is Akero Therapeutics, Inc. The number in brackets is how many trials each organisation leads.

Where does this information come from?

Every trial, status, phase and sponsor on this page is copied from public ClinicalTrials.gov records by a daily sync. Nothing here describes how Efruxifermin works or whether it is effective, and it is not medical advice.

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How this page is built

Everything on this page is copied from public ClinicalTrials.gov registry records — it is not written from memory, and nothing here describes how Efruxifermin works or whether it is effective. Each trial links to its own record so you can check it yourself.

This page is built automatically: a daily sync job reads the registry records behind our country trial registers, collects every trial that lists Efruxifermin (or a registered synonym) as a drug or biological intervention, and tabulates the registry fields directly. Placebos and generic comparators are excluded. There is no AI drafting and no per-compound editorial pass, and the page has not been clinically reviewed. The “last verified” date above is the timestamp of that sync, not a review date. Our general editorial approach is described in our editorial standards and corrections policy. The ClinicalTrials.gov data on this page was last retrieved on 10 Nov 2026. How every register is built: methodology · fixes we have made: corrections log.

Please verify before you rely on this. This page is general information for life-science and pharmaceutical professionals. It is not medical advice, and it has not been reviewed by a clinician — our editorial team holds life-science qualifications, not clinical ones. It is not exhaustive and may not reflect the most recent label change. Always check the official prescribing information (US Prescribing Information or EU SmPC) and speak to your doctor or pharmacist before acting on anything here. Drugs in the same class are not automatically interchangeable, and approvals, brand names and indications differ between the US, the EU/Ireland (EMA/HPRA) and other regions. Spotted an error? Tell us — we correct promptly and log it.